[go: up one dir, main page]

AR027291A1 - Atenuacion recombinante de prrsv - Google Patents

Atenuacion recombinante de prrsv

Info

Publication number
AR027291A1
AR027291A1 ARP010100333A ARP010100333A AR027291A1 AR 027291 A1 AR027291 A1 AR 027291A1 AR P010100333 A ARP010100333 A AR P010100333A AR P010100333 A ARP010100333 A AR P010100333A AR 027291 A1 AR027291 A1 AR 027291A1
Authority
AR
Argentina
Prior art keywords
orf
viruses
prrsv
recombinating
attention
Prior art date
Application number
ARP010100333A
Other languages
English (en)
Original Assignee
Boehringer Ingelheim Vetmed
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2000103373 external-priority patent/DE10003373A1/de
Priority claimed from DE2000103371 external-priority patent/DE10003371A1/de
Priority claimed from DE2000103372 external-priority patent/DE10003372A1/de
Application filed by Boehringer Ingelheim Vetmed filed Critical Boehringer Ingelheim Vetmed
Publication of AR027291A1 publication Critical patent/AR027291A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04—Inactivation or attenuation; Producing viral sub-units
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10061—Methods of inactivation or attenuation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Surface Acoustic Wave Elements And Circuit Networks Thereof (AREA)

Abstract

Virus de PRRS vivos que están atenuados por mutaciones de aminoácidos en un sitio específico de la proteína viral codificada por el marco de lecturaabierto (ORF), seleccionado del grupo de ORF 1a, ORF 1b, y/u ORF 2. La presente también pertenece a se cuencias de nucleotidos que codifican dichos virus, amétodos para generar tales virus y a su uso para la preparacion de una composicion farmacéutica para la profilaxis y el tratamiento de infecciones de PRRS.
ARP010100333A 2000-01-26 2001-01-26 Atenuacion recombinante de prrsv AR027291A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE2000103373 DE10003373A1 (de) 2000-01-26 2000-01-26 Rekombinante Attenuation von PRRSV
DE2000103371 DE10003371A1 (de) 2000-01-26 2000-01-26 Rekombinante Attenuation von PRRSV
DE2000103372 DE10003372A1 (de) 2000-01-26 2000-01-26 Rekombinante Attenuation von PRRSV

Publications (1)

Publication Number Publication Date
AR027291A1 true AR027291A1 (es) 2003-03-19

Family

ID=27213605

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP010100333A AR027291A1 (es) 2000-01-26 2001-01-26 Atenuacion recombinante de prrsv

Country Status (15)

Country Link
EP (1) EP1254213A2 (es)
JP (1) JP2003520601A (es)
KR (1) KR20030032910A (es)
CN (1) CN1406277A (es)
AR (1) AR027291A1 (es)
AU (1) AU2001228502A1 (es)
BR (1) BR0107827A (es)
CA (1) CA2396454A1 (es)
CZ (1) CZ20022554A3 (es)
EA (1) EA200200743A1 (es)
HU (1) HUP0204176A3 (es)
MX (1) MXPA02007198A (es)
PL (1) PL356274A1 (es)
SK (1) SK10932002A3 (es)
WO (1) WO2001055353A2 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2003129068A (ru) * 2001-03-09 2005-04-10 Бёрингер Ингельхайм Ветмедика Гмбх (De) Штаммы вируса репродуктивного и респираторного синдрома свиней (prrs) с ослабленной жизнеспособностью
US6841364B2 (en) 2002-01-22 2005-01-11 Protatek International, Inc. Infectious cDNA clones of porcine reproductive and respiratory syndrome virus and expression vectors thereof
JP2007524363A (ja) 2003-03-27 2007-08-30 オタワ ヘルス リサーチ インスティチュート 変異体水疱性口内炎ウイルスおよびそれらの使用
BRPI0606189A2 (pt) * 2005-02-25 2009-06-09 Pfizer Prod Inc composição, vacina e método para proteger um animal porcino de infecção por um vìrus de prrs, célula hospedeira transfectada, método para fazer um vìrus de prrs geneticamente modificado e atenuado
CN100439494C (zh) * 2007-03-14 2008-12-03 中国动物疫病预防控制中心 猪繁殖与呼吸综合征疫苗、制备方法及应用
US7666585B2 (en) 2007-06-15 2010-02-23 Protatek International, Inc. Construction of chimera PRRSV, compositions and vaccine preparations
CN101307305B (zh) * 2008-04-30 2010-06-16 中国动物疫病预防控制中心 一种猪繁殖与呼吸综合征病毒弱毒株及免疫原性物质和疫苗
UA108902C2 (uk) * 2010-11-10 2015-06-25 Вірус північноамериканського репродуктивного та респіраторного синдрому свиней (prrs) та його застосування
EP3119429A4 (en) * 2014-03-21 2018-04-04 Nutech Ventures A non-naturally occuring porcine reproductive and respiratory syndrome virus (prrsv) and methods of using

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6251397B1 (en) * 1992-10-30 2001-06-26 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus and immunogenic compositions containing the same
CA2196555C (en) * 1994-08-05 2012-07-03 Michael P. Murtaugh Vr-2332 viral nucleotide sequence and methods of use
EP0839912A1 (en) * 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof

Also Published As

Publication number Publication date
CZ20022554A3 (cs) 2002-10-16
WO2001055353A3 (en) 2001-12-27
HUP0204176A2 (hu) 2003-04-28
AU2001228502A1 (en) 2001-08-07
BR0107827A (pt) 2002-11-05
CA2396454A1 (en) 2001-08-02
HUP0204176A3 (en) 2003-12-29
WO2001055353A2 (en) 2001-08-02
MXPA02007198A (es) 2002-12-09
JP2003520601A (ja) 2003-07-08
SK10932002A3 (sk) 2002-11-06
EP1254213A2 (en) 2002-11-06
KR20030032910A (ko) 2003-04-26
PL356274A1 (en) 2004-06-28
CN1406277A (zh) 2003-03-26
EA200200743A1 (ru) 2002-12-26

Similar Documents

Publication Publication Date Title
BR0207988A (pt) Cepas atenuadas vivas de vìrus de prrs
UY26724A1 (es) Métodos y composiciones para tratar el virus de la hepatitis c
DE60119968D1 (en) Hepatitis c tripeptid inhibitoren
ATE295180T1 (de) Zubereitung zur immunisierung gegen den aids- virus
BR9912178A (pt) Vacinas de peptìdeo sintéticas para febre aftosa
AR107020A2 (es) Vacuna de pcsk9 (proteína convertasa subtilisina-kexina tipo 9)
SG146648A1 (en) Pharmaceutical compositions for treating premature ejaculation by pulmonary inhalation
PE20020474A1 (es) Compuestos peptidomimeticos como inhibidores de la serina proteasa ns3 del virus de hepatitis c
BR0012919A (pt) Vacina para uso na profilaxia e/ou no tratamento da sìndrome de ponto branco (white spot syndrome) em crustáceos, proteìna estrutural derivada do vìrus da sìndrome de ponto branco, sequência de ácido nucléico, uso de uma proteìna estrutural, composição farmacêutica, anticorpos, vacina ou formulação farmacêutica, e, kit diagnóstico para detecção de wssv
AR027291A1 (es) Atenuacion recombinante de prrsv
AR057695A1 (es) Procedimientos de administracion de vacunas contra calcivirus felinos, y tratamientos para inmunizar animales contra parvovirus felino y herpes virus felino
PE20020287A1 (es) Procedimiento para la purificacion de un antigeno del virus de la hepatitis b
AR004464A1 (es) Un metodo para producir una proteina de capside de papilomavirus
DK1149910T3 (da) Farmaceutisk præparat til behandling af papillomavirustumorer og -infektion
HUP9901958A2 (hu) Sertés reproduktív és respirációs szindróma vakcina
DE60136563D1 (de) Salmonella vakzine
EA200400530A1 (ru) Перекрестно-сшитые антибиотики "гликопептид-цефалоспорин"
JP2006512078A5 (es)
CL2009000791A1 (es) Compuestos derivados de labirintopeptina; procedimiento para prepararlos que comprende fermentar la cepa actinomadura namibiensis (dsm 6313); uso de los compuestos para tratar infecciones bacterianas, infecciones viricas y/o dolor; composicion farmaceutica que los comprenden; dna que codifica la preprolabirintopeptina a2.
RU2008144180A (ru) Вакцина против микоплазмы и prrsv
BR0014666A (pt) Vacina
UY26563A1 (es) Atenuación recombinante de prrsv
AR085800A1 (es) Vacuna de rinitis equina
ES2153284B1 (es) Nuevo virus recombinante de mixoma atenuado y su uso en la preparacion de vacunas mixtas contra la mixomatosis y la enfermedad hemorragica de los conejos.
CR20240374A (es) Antígenos tumorales, compuestos que comprenden los antígenos tumorales kras, tpx2 o aurka y usos de los mismos

Legal Events

Date Code Title Description
FB Suspension of granting procedure