AR026105A1 - HETEROARILO, HETEROCICLICO AND ILO COMPUTERS THAT - Google Patents
HETEROARILO, HETEROCICLICO AND ILO COMPUTERS THATInfo
- Publication number
- AR026105A1 AR026105A1 ARP000100287A ARP000100287A AR026105A1 AR 026105 A1 AR026105 A1 AR 026105A1 AR P000100287 A ARP000100287 A AR P000100287A AR P000100287 A ARP000100287 A AR P000100287A AR 026105 A1 AR026105 A1 AR 026105A1
- Authority
- AR
- Argentina
- Prior art keywords
- compounds
- disease
- heterociclico
- heteroarilo
- ilo
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se describen compuestos que se adhieren a VLA-4. Algunos de estos compuestos inhiben también la adhesion de leucocitos, y un particular, la adhesion deleucocitos intermedia por VLA-4 de los compuestos utiles para el tratamiento de enfermedades inflam atorias en un paciente mamífero, por ejemplo en un serhumano, tales como asma, enfermedad de Alzheimer, ateroes-clerosis, demencia causada por SIDA, diabetes, enfermedad inflamatoria del intestino, artritisreumatoide, transplante de tejidos, metástas is de tumores e isquemia de miocardio. Los compuestos pueden suministrarse también para el tratamiento deenfermedades cerebrales inflamatorias tales como esclerosis multiple.Compounds that adhere to VLA-4 are described. Some of these compounds also inhibit the adhesion of leukocytes, and in particular, the adhesion deleucocytes intermediate by VLA-4 of the compounds useful for the treatment of inflammatory diseases in a mammalian patient, for example in a human being, such as asthma, disease Alzheimer's disease, atherosclerosis, dementia caused by AIDS, diabetes, inflammatory bowel disease, rheumatoid arthritis, tissue transplantation, tumor metastases and myocardial ischemia. The compounds can also be supplied for the treatment of inflammatory brain diseases such as multiple sclerosis.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1199996A | 1996-04-09 | 1996-04-09 | |
| US11692399P | 1999-01-22 | 1999-01-22 | |
| US16099999P | 1999-10-21 | 1999-10-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR026105A1 true AR026105A1 (en) | 2003-01-29 |
Family
ID=37515090
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP000100287A AR026105A1 (en) | 1996-04-09 | 2000-01-24 | HETEROARILO, HETEROCICLICO AND ILO COMPUTERS THAT |
Country Status (1)
| Country | Link |
|---|---|
| AR (1) | AR026105A1 (en) |
-
2000
- 2000-01-24 AR ARP000100287A patent/AR026105A1/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |