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AR025962A1 - Imidazo-3-il-aminas biciclicas, procedimiento para su preparacion y medicamentos que los contienen - Google Patents

Imidazo-3-il-aminas biciclicas, procedimiento para su preparacion y medicamentos que los contienen

Info

Publication number
AR025962A1
AR025962A1 ARP000105254A ARP000105254A AR025962A1 AR 025962 A1 AR025962 A1 AR 025962A1 AR P000105254 A ARP000105254 A AR P000105254A AR P000105254 A ARP000105254 A AR P000105254A AR 025962 A1 AR025962 A1 AR 025962A1
Authority
AR
Argentina
Prior art keywords
amines
preparation
imidazo
bicycle
procedure
Prior art date
Application number
ARP000105254A
Other languages
English (en)
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE1999148438 external-priority patent/DE19948438B4/de
Priority claimed from DE19948434A external-priority patent/DE19948434A1/de
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of AR025962A1 publication Critical patent/AR025962A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Imidazo-3-il-aminas bicíclicas de la formula general (1) en forma de sus bases o sus sales farmacéuticamente aceptables, procedimiento para su preparaciony medicamentos que contienen como sustancia activa al menos una imidazo-3-il-amina bicíclica dela formula general (1) en forma de su base o una salfarmacéuticamente aceptable.
ARP000105254A 1999-10-08 2000-10-05 Imidazo-3-il-aminas biciclicas, procedimiento para su preparacion y medicamentos que los contienen AR025962A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE1999148438 DE19948438B4 (de) 1999-10-08 1999-10-08 Bicyclische Imidazo-3-aminderivate
DE19948434A DE19948434A1 (de) 1999-10-08 1999-10-08 Substanzbibliothek enthaltend bicyclische Imidazo-5-amine und/oder bicyclische Imidazo-3-amine

Publications (1)

Publication Number Publication Date
AR025962A1 true AR025962A1 (es) 2002-12-26

Family

ID=26055218

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000105254A AR025962A1 (es) 1999-10-08 2000-10-05 Imidazo-3-il-aminas biciclicas, procedimiento para su preparacion y medicamentos que los contienen

Country Status (26)

Country Link
US (1) US6638933B2 (es)
EP (1) EP1218382B1 (es)
JP (1) JP2003511451A (es)
KR (1) KR100756592B1 (es)
CN (1) CN1257169C (es)
AR (1) AR025962A1 (es)
AT (1) ATE258554T1 (es)
AU (1) AU779197B2 (es)
BR (1) BR0014818A (es)
CA (1) CA2382919C (es)
CO (1) CO5251378A1 (es)
CZ (1) CZ20021210A3 (es)
DE (1) DE50005155D1 (es)
DK (1) DK1218382T3 (es)
ES (1) ES2213611T3 (es)
HK (1) HK1047747B (es)
HU (1) HUP0203052A3 (es)
NO (1) NO322754B1 (es)
NZ (2) NZ518390A (es)
PE (1) PE20010634A1 (es)
PL (1) PL355206A1 (es)
PT (1) PT1218382E (es)
RU (1) RU2264402C2 (es)
SK (1) SK286788B6 (es)
UY (1) UY26372A1 (es)
WO (1) WO2001027111A2 (es)

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US20040077605A1 (en) * 2001-06-20 2004-04-22 Salvati Mark E. Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
DE10043845A1 (de) * 2000-09-06 2002-03-14 Gruenenthal Gmbh Verfahren zur Messung der Aktivität der NO-Synthase
EP1854798A3 (en) 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
WO2002048146A2 (de) * 2000-12-13 2002-06-20 Basf Aktiengesellschaft Verwendung von substituierten imidazoazinen, neue imidazoazine, verfahren zu deren herstellung, sowie sie enthaltende mittel
US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
AU2002364082A1 (en) 2001-12-19 2003-07-09 Bristol-Myers Squibb Company Fused heterocyclic compounds and analogs thereof: modulators of nuclear hormone receptor function
DE102004021716A1 (de) * 2004-04-30 2005-12-01 Grünenthal GmbH Substituierte Imidazo[1,2-a]pyridin-Verbindungen und Arzneimittel enthaltend substituierte Imidazo[1,2-a]pyridin-Verbindungen
WO2006131003A1 (en) * 2005-06-09 2006-12-14 Oncalis Ag Angiogenesis inhibitors
DE602005013085D1 (de) * 2004-06-09 2009-04-16 Oncalis Ag Proteinkinaseinhibitoren
US7923041B2 (en) * 2005-02-03 2011-04-12 Signum Biosciences, Inc. Compositions and methods for enhancing cognitive function
KR100973609B1 (ko) * 2005-03-23 2010-08-03 에프. 호프만-라 로슈 아게 ｍＧｌｕＲ2 길항제로서 아세틸렌일-피라졸로-피리미딘유도체
CN101263142A (zh) * 2005-05-20 2008-09-10 阿雷生物药品公司 Raf抑制剂化合物及其使用方法
US7709468B2 (en) 2005-09-02 2010-05-04 Abbott Laboratories Imidazo based heterocycles
BRPI0620760A2 (pt) * 2005-12-27 2011-11-22 Hoffmann La Roche derivados de aril-isoxazol-4-il-imidazo[1,5]piridina
BRPI0706560A2 (pt) * 2006-01-17 2011-03-29 Hoffmann La Roche derivados de aril-isoxazol-4-il-imidazo [1,2-a] piridina úteis para o tratamento de doença de alzheimer por intermédio de receptores gaba
EP1845098A1 (en) * 2006-03-29 2007-10-17 Ferrer Internacional, S.A. Imidazo[1,2-b]pyridazines, their processes of preparation and their use as GABA receptor ligands
KR20090026288A (ko) * 2006-05-31 2009-03-12 갈라파고스 엔.브이. 퇴행성 및 염증성 질환의 치료에 유용한 트리아졸로피라진 화합물
US8227603B2 (en) * 2006-08-01 2012-07-24 Cytokinetics, Inc. Modulating skeletal muscle
WO2008016648A2 (en) * 2006-08-01 2008-02-07 Cytokinetics, Incorporated Certain chemical entities, compositions and methods
JP5249217B2 (ja) * 2006-08-02 2013-07-31 サイトキネティクス・インコーポレーテッド 特定の化学物質、組成物及び方法
US8299248B2 (en) 2006-08-02 2012-10-30 Cytokinetics, Incorporated Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols and methods for their use
EP1974729A1 (en) * 2007-03-28 2008-10-01 Santhera Pharmaceuticals (Schweiz) AG Substituted imidazopyridine derivates as melanocortin- 4 receptor antagonists
WO2008121333A1 (en) * 2007-03-30 2008-10-09 Cytokinetics, Incorporated Certain chemical entities, compositions and methods
GB0708188D0 (en) * 2007-04-27 2007-06-06 Merck Sharp & Dohme Therapeutic compounds
PL2266990T3 (pl) * 2008-04-15 2013-03-29 Eisai R&D Man Co Ltd ZWIĄZEK 3-FENYLOPIRAZOLO[5,1-b] TIAZOLOWY
AU2009268406A1 (en) * 2008-07-10 2010-01-14 Southern Research Institute 5-Quinolinone and Imidazopyridine compounds and use thereof
EP2334675B1 (en) * 2008-09-16 2014-03-26 Csir Imidazopyridines and imidazopyrimidines as hiv-i reverse transcriptase inhibitors
CN105219734B (zh) 2008-12-05 2020-03-03 武田疫苗公司 用于诱导病毒生长的组合物、方法和用途
AR078521A1 (es) * 2009-10-08 2011-11-16 Eisai R&D Man Co Ltd Compuesto pirazolotiazol
EP2731611B1 (en) 2011-07-13 2019-09-18 Cytokinetics, Inc. Combination therapie for als
BR112015010469A2 (pt) * 2012-11-14 2017-07-11 Hoffmann La Roche derivados de imidazopiridina
SG11201507224RA (en) * 2013-03-14 2015-10-29 Galapagos Nv Compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders
WO2017160922A1 (en) 2016-03-16 2017-09-21 Kalyra Pharmaceuticals, Inc. Analgesic compounds
EP3615532A4 (en) * 2017-04-28 2020-11-18 Dana Farber Cancer Institute, Inc. TRIM33 INHIBITORS AND METHODS OF USE
WO2019070943A1 (en) * 2017-10-04 2019-04-11 Dana-Farber Cancer Institute, Inc. SMALL MOLECULE INHIBITION OF SALL4 TRANSCRIPTION FACTOR AND USES THEREOF

Family Cites Families (8)

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Publication number Priority date Publication date Assignee Title
EP0068378B1 (en) 1981-06-26 1986-03-05 Schering Corporation Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
NZ221996A (en) * 1986-10-07 1989-08-29 Yamanouchi Pharma Co Ltd Imidazo-pyridine derivatives and pharmaceutical compositions
RU2043716C1 (ru) * 1989-06-23 1995-09-20 Такеда Кемикал Индастриз Лтд. Амидное производное и фунгицидный состав на его основе
NZ238863A (en) * 1990-07-19 1993-03-26 Janssen Pharmaceutica Nv Substituted thiazolyl and pyridinyl derivatives
TW274551B (es) * 1991-04-16 1996-04-21 Takeda Pharm Industry Co Ltd
DE4327027A1 (de) * 1993-02-15 1994-08-18 Bayer Ag Imidazoazine
KR19990007836A (ko) * 1995-04-21 1999-01-25 다나까 테츠오 융합된 이미다조[1, 2-a]피리딘
AU2001270297A1 (en) * 2000-06-30 2002-01-14 Neurogen Corporation 2-phenylimidazo(1,2-a)pyridine derivatives: a new class of gaba brain receptor ligands

Also Published As

Publication number Publication date
SK4362002A3 (en) 2002-08-06
ATE258554T1 (de) 2004-02-15
PE20010634A1 (es) 2001-07-07
WO2001027111A3 (de) 2001-06-14
ES2213611T3 (es) 2004-09-01
CO5251378A1 (es) 2003-02-28
CN1391573A (zh) 2003-01-15
KR100756592B1 (ko) 2007-09-10
AU779197B2 (en) 2005-01-13
NO20021565L (no) 2002-05-27
JP2003511451A (ja) 2003-03-25
NZ518439A (en) 2003-10-31
SK286788B6 (sk) 2009-05-07
CA2382919A1 (en) 2001-04-19
BR0014818A (pt) 2002-06-18
UY26372A1 (es) 2000-12-29
CN1257169C (zh) 2006-05-24
EP1218382B1 (de) 2004-01-28
US20030018032A1 (en) 2003-01-23
HUP0203052A2 (hu) 2003-01-28
HUP0203052A3 (en) 2004-06-28
DE50005155D1 (de) 2004-03-04
US6638933B2 (en) 2003-10-28
PL355206A1 (en) 2004-04-05
CZ20021210A3 (cs) 2002-08-14
HK1047747B (zh) 2004-12-03
NO322754B1 (no) 2006-12-04
NZ518390A (en) 2003-10-31
NO20021565D0 (no) 2002-04-03
EP1218382A2 (de) 2002-07-03
PT1218382E (pt) 2004-06-30
HK1047747A1 (zh) 2003-03-07
DK1218382T3 (da) 2004-03-22
CA2382919C (en) 2008-12-09
RU2264402C2 (ru) 2005-11-20
KR20020038805A (ko) 2002-05-23
WO2001027111A2 (de) 2001-04-19
AU7777100A (en) 2001-04-23

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