AR025111A1 - Metodos y composiciones para tratar trastornos de ansiedad generalizada - Google Patents
Metodos y composiciones para tratar trastornos de ansiedad generalizadaInfo
- Publication number
- AR025111A1 AR025111A1 ARP000104190A ARP000104190A AR025111A1 AR 025111 A1 AR025111 A1 AR 025111A1 AR P000104190 A ARP000104190 A AR P000104190A AR P000104190 A ARP000104190 A AR P000104190A AR 025111 A1 AR025111 A1 AR 025111A1
- Authority
- AR
- Argentina
- Prior art keywords
- compositions
- methods
- generalized anxiety
- anxiety disorders
- treat generalized
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 208000037870 generalized anxiety Diseases 0.000 title 1
- 208000011688 Generalised anxiety disease Diseases 0.000 abstract 2
- JURKNVYFZMSNLP-UHFFFAOYSA-N cyclobenzaprine Chemical compound C1=CC2=CC=CC=C2C(=CCCN(C)C)C2=CC=CC=C21 JURKNVYFZMSNLP-UHFFFAOYSA-N 0.000 abstract 2
- 229960003572 cyclobenzaprine Drugs 0.000 abstract 2
- 208000029364 generalized anxiety disease Diseases 0.000 abstract 2
- 239000002207 metabolite Substances 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Anesthesiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Métodos y composiciones que comprenden una dosis muy baja de ciclobenzaprina o metabolito de la misma para prevenir y tratar el trastorno de ansiedadgeneralizada. La presente se refiere además a métodos y composiciones para tratar y prevenirsíntomas asociados con el trastorno de ansiedad generalizada,usando una dosis muy baja de ciclobenzaprina.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14888199P | 1999-08-13 | 1999-08-13 | |
| US21192200P | 2000-06-16 | 2000-06-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR025111A1 true AR025111A1 (es) | 2002-11-06 |
Family
ID=26846257
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP000104190A AR025111A1 (es) | 1999-08-13 | 2000-08-11 | Metodos y composiciones para tratar trastornos de ansiedad generalizada |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6358944B1 (es) |
| EP (1) | EP1202721A1 (es) |
| JP (1) | JP2003506483A (es) |
| AR (1) | AR025111A1 (es) |
| AU (1) | AU6634000A (es) |
| BR (1) | BR0013122A (es) |
| CA (1) | CA2380373A1 (es) |
| ES (1) | ES2212737B1 (es) |
| GB (1) | GB2368283A (es) |
| HK (2) | HK1047693A1 (es) |
| IL (1) | IL147778A0 (es) |
| MX (1) | MXPA02001568A (es) |
| WO (1) | WO2001012174A1 (es) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6733789B1 (en) | 1999-01-21 | 2004-05-11 | Biovail Laboratories, Inc. | Multiparticulate bisoprolol formulation |
| CA2380432A1 (en) * | 1999-08-13 | 2001-02-22 | Iredell W. Iglehart, Iii | Uses compositions for treating or preventing sleep disturbances using very low doses of cyclobenzaprine |
| US20040185099A1 (en) * | 2000-01-20 | 2004-09-23 | Biovail Laboratories, Inc. | Multiparticulate bisoprolol formulation |
| CA2446904A1 (en) * | 2001-05-24 | 2003-04-03 | Alexza Molecular Delivery Corporation | Delivery of drug esters through an inhalation route |
| AU2002347906A2 (en) * | 2001-10-16 | 2003-04-28 | Hypnion, Inc. | Treatment of CNS disorders using CNS target modulators |
| US7189757B2 (en) * | 2001-10-16 | 2007-03-13 | Hypnion, Inc. | Treatment of sleep disorders using CNS target modulators |
| US20030091633A1 (en) * | 2001-11-15 | 2003-05-15 | John Kelly | Methods and compositions for use of (S)-bisoprolol |
| US20030118652A1 (en) * | 2001-11-15 | 2003-06-26 | John Kelly | Methods and compositions for use of (S)-bisoprolol |
| EP1499309A4 (en) * | 2002-04-24 | 2008-05-28 | Cypress Bioscience Inc | PREVENTION AND TREATMENT OF FUNCTIONAL SOMATIC DISEASES, INCLUDING STRESS-BASED DISEASES |
| EP1530476A1 (en) * | 2002-08-14 | 2005-05-18 | Pharmacia & Upjohn Company LLC | Use of reboxetine for the treatment of hot flashes |
| US20060217367A1 (en) * | 2004-07-01 | 2006-09-28 | Astrazeneca Ab | Method of treating anxiety disorders |
| NZ527142A (en) * | 2003-07-23 | 2006-03-31 | Douglas Pharmaceuticals Ltd | A stable suspension formulation |
| US7387793B2 (en) * | 2003-11-14 | 2008-06-17 | Eurand, Inc. | Modified release dosage forms of skeletal muscle relaxants |
| GB0400895D0 (en) * | 2004-01-15 | 2004-02-18 | Smithkline Beecham Corp | Chemical compounds |
| US7517908B2 (en) * | 2004-05-21 | 2009-04-14 | Duke University | Method for augmenting the effects of serotonin reuptake inhibitors |
| TW200616967A (en) * | 2004-06-24 | 2006-06-01 | Smithkline Beecham Corp | Novel indazole carboxamides and their use |
| NL1026634C2 (nl) * | 2004-07-12 | 2006-01-16 | Willem Jacob Van Der Burg | Psychofarmaceutisch preparaat en werkzame stof daarin. |
| US8063071B2 (en) * | 2007-10-31 | 2011-11-22 | GlaxoSmithKline, LLC | Chemical compounds |
| US20070087055A1 (en) * | 2005-10-14 | 2007-04-19 | David Jan | Directly compressible extended release alprazolam formulation |
| JP5415767B2 (ja) * | 2005-11-10 | 2014-02-12 | ボード オブ スーパーバイザーズ オブ ルイジアナ ステイト ユニバーシティー アンド アグリカルチュラル アンド メカニカル カレッジ | 依存症及び他の精神神経疾患の治療のための組成物及び方法 |
| JP2009516702A (ja) * | 2005-11-18 | 2009-04-23 | スミスクライン・ビーチャム・コーポレイション | 化合物 |
| US8357114B2 (en) | 2006-01-06 | 2013-01-22 | Acelrx Pharmaceuticals, Inc. | Drug dispensing device with flexible push rod |
| US8865743B2 (en) | 2006-01-06 | 2014-10-21 | Acelrx Pharmaceuticals, Inc. | Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain |
| US8252328B2 (en) | 2006-01-06 | 2012-08-28 | Acelrx Pharmaceuticals, Inc. | Bioadhesive drug formulations for oral transmucosal delivery |
| US9066847B2 (en) * | 2007-01-05 | 2015-06-30 | Aceirx Pharmaceuticals, Inc. | Storage and dispensing devices for administration of oral transmucosal dosage forms |
| US8535714B2 (en) | 2006-01-06 | 2013-09-17 | Acelrx Pharmaceuticals, Inc. | Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain |
| US8252329B2 (en) | 2007-01-05 | 2012-08-28 | Acelrx Pharmaceuticals, Inc. | Bioadhesive drug formulations for oral transmucosal delivery |
| US8202535B2 (en) | 2006-01-06 | 2012-06-19 | Acelrx Pharmaceuticals, Inc. | Small-volume oral transmucosal dosage forms |
| US8753308B2 (en) | 2006-01-06 | 2014-06-17 | Acelrx Pharmaceuticals, Inc. | Methods for administering small volume oral transmucosal dosage forms using a dispensing device |
| US9289583B2 (en) * | 2006-01-06 | 2016-03-22 | Acelrx Pharmaceuticals, Inc. | Methods for administering small volume oral transmucosal dosage forms using a dispensing device |
| US8513299B2 (en) * | 2006-05-19 | 2013-08-20 | Pernix Sleep, Inc. | Methods of using low-dose doxepin for the improvement of sleep |
| US7645750B2 (en) * | 2006-12-13 | 2010-01-12 | Yung Shin Pharmaceutical Ind. Co., Ltd. | Method of treating symptoms of hormonal variations |
| GB0701970D0 (en) | 2007-02-01 | 2007-03-14 | Wilson Stuart | Treatment of protein aggregation diseases |
| PE20081889A1 (es) * | 2007-03-23 | 2009-03-05 | Smithkline Beecham Corp | Indol carboxamidas como inhibidores de ikk2 |
| WO2008128166A1 (en) * | 2007-04-13 | 2008-10-23 | Concert Pharmaceuticals Inc. | Deuterated derivatives of 4-(6-fluoro-1, 2-benzisoxazol-3-yl) piperidine compounds |
| JP5632284B2 (ja) * | 2007-08-07 | 2014-11-26 | エーセルアールエックス ファーマシューティカルズ, インコーポレイテッド | 経口経粘膜剤形を使用する処置時の鎮静および無痛のための組成物および方法 |
| US8420624B2 (en) * | 2007-12-04 | 2013-04-16 | Yung Shin Pharm. Ind. Co., Ltd. | Methods for treating or preventing symptoms of hormonal variations |
| US20110092493A1 (en) * | 2008-09-24 | 2011-04-21 | Clark Levi | Dose-controlled transdermal promethazine compositions and methods of use |
| US8945592B2 (en) * | 2008-11-21 | 2015-02-03 | Acelrx Pharmaceuticals, Inc. | Sufentanil solid dosage forms comprising oxygen scavengers and methods of using the same |
| US9498440B2 (en) | 2009-05-22 | 2016-11-22 | Inventia Healthcare Private Limited | Extended release pharmaceutical compositions |
| US20110091544A1 (en) * | 2009-10-16 | 2011-04-21 | Acelrx Pharmaceuticals, Inc. | Compositions and Methods for Mild Sedation, Anxiolysis and Analgesia in the Procedural Setting |
| SMT201700578T1 (it) * | 2009-11-20 | 2018-01-11 | Tonix Pharma Holdings Ltd | Metodo e composizioni per trattare i sintomi associati al disturbo da stress post-traumatico usando ciclobenzaprina |
| US20110319389A1 (en) | 2010-06-24 | 2011-12-29 | Tonix Pharmaceuticals, Inc. | Methods and compositions for treating fatigue associated with disordered sleep using very low dose cyclobenzaprine |
| EP2629615B1 (en) | 2010-10-22 | 2018-10-10 | Duke University | Slow-release formulations of 5-hydroxytryptophan as an adjunct to pro-serotonergic therapies |
| US11998516B2 (en) | 2011-03-07 | 2024-06-04 | Tonix Pharma Holdings Limited | Methods and compositions for treating depression using cyclobenzaprine |
| HUE060175T2 (hu) | 2012-06-15 | 2023-02-28 | Tonix Pharma Holdings Ltd | Transzmukózális felszívódásra szolgáló készítmények és módszerek |
| RS65500B1 (sr) | 2013-03-15 | 2024-06-28 | Tonix Pharma Holdings Ltd | Eutektičke formulacije ciklobenzaprin hidrohlorida i manitola |
| MY186047A (en) | 2014-09-18 | 2021-06-17 | Tonix Pharma Holdings Ltd | Eutectic formulations of cyclobenzaprine hydrochloride |
| CA3069699A1 (en) | 2017-07-13 | 2019-01-17 | Tonix Pharmaceuticals Holding Corp. | Analogs of cyclobenzaprine and amitryptilene |
| JP2021505629A (ja) | 2017-12-11 | 2021-02-18 | トニックス ファーマ ホールディングス リミテッド | 認知症および神経変性状態における興奮、精神病および認知機能低下のためのシクロベンザプリン処置 |
| WO2020039256A1 (en) * | 2018-08-20 | 2020-02-27 | Tonix Pharma Holdings Limited | Methods of treating acute stress disorder and posttraumatic stress disorder |
| MX2023005899A (es) | 2020-11-20 | 2023-08-16 | TONIX Pharmaceuticals Holding Corp | Tratamiento con ciclobenzaprina para el trastorno por consumo de alcohol. |
| KR102397333B1 (ko) * | 2020-12-21 | 2022-05-13 | 주식회사 스탠다임 | 클레마스틴을 포함하는 강박장애, 틱 장애 또는 뚜렛 증후군 예방 또는 치료용 약학 조성물 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1339636A (en) * | 1917-02-23 | 1920-05-11 | Tulloch Thomas Gregorie | Fluid-tight joint for steam-pipes and the like |
| GB859187A (en) | 1958-11-25 | 1961-01-18 | United States Borax Chem | Method for preparing substituted tris amino boranes |
| CA958643A (en) | 1970-07-07 | 1974-12-03 | Frosst (Charles E.) And Co. | Pharmaceutical compositions containing cyclobenzaprine |
| FR2121529A1 (en) * | 1971-01-05 | 1972-08-25 | Merck & Co Inc | Compsns contg cyclobenzaprine and indomethacin - chlordiazepoxide, phenylbutazone oxyphenbutazone or corticosteroid |
| US3882246A (en) * | 1971-05-21 | 1975-05-06 | Merck & Co Inc | Treatment of skeletal muscle disorders with cyclobenzaprine |
-
2000
- 2000-08-11 GB GB0203286A patent/GB2368283A/en not_active Withdrawn
- 2000-08-11 US US09/638,058 patent/US6358944B1/en not_active Expired - Lifetime
- 2000-08-11 IL IL14777800A patent/IL147778A0/xx unknown
- 2000-08-11 BR BR0013122-9A patent/BR0013122A/pt not_active Application Discontinuation
- 2000-08-11 MX MXPA02001568A patent/MXPA02001568A/es unknown
- 2000-08-11 JP JP2001516520A patent/JP2003506483A/ja active Pending
- 2000-08-11 WO PCT/US2000/022026 patent/WO2001012174A1/en not_active Ceased
- 2000-08-11 EP EP00953980A patent/EP1202721A1/en not_active Withdrawn
- 2000-08-11 AU AU66340/00A patent/AU6634000A/en not_active Abandoned
- 2000-08-11 HK HK02107670.0A patent/HK1047693A1/zh unknown
- 2000-08-11 HK HK02107669.3A patent/HK1047692A1/zh unknown
- 2000-08-11 CA CA002380373A patent/CA2380373A1/en not_active Abandoned
- 2000-08-11 AR ARP000104190A patent/AR025111A1/es unknown
- 2000-08-11 ES ES200250017A patent/ES2212737B1/es not_active Withdrawn - After Issue
Also Published As
| Publication number | Publication date |
|---|---|
| ES2212737B1 (es) | 2005-10-01 |
| JP2003506483A (ja) | 2003-02-18 |
| MXPA02001568A (es) | 2002-07-02 |
| CA2380373A1 (en) | 2001-02-22 |
| WO2001012174A1 (en) | 2001-02-22 |
| IL147778A0 (en) | 2002-08-14 |
| ES2212737A1 (es) | 2004-07-16 |
| BR0013122A (pt) | 2002-04-30 |
| HK1047693A1 (zh) | 2003-03-07 |
| AU6634000A (en) | 2001-03-13 |
| HK1047692A1 (zh) | 2003-03-07 |
| GB0203286D0 (en) | 2002-03-27 |
| GB2368283A (en) | 2002-05-01 |
| US6358944B1 (en) | 2002-03-19 |
| EP1202721A1 (en) | 2002-05-08 |
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