AR010195A1 - Antagonistas de vasopresina de benzacepina triciclicos y procedimiento para su preparacion. - Google Patents
Antagonistas de vasopresina de benzacepina triciclicos y procedimiento para su preparacion.Info
- Publication number
- AR010195A1 AR010195A1 ARP960101028A AR10102896A AR010195A1 AR 010195 A1 AR010195 A1 AR 010195A1 AR P960101028 A ARP960101028 A AR P960101028A AR 10102896 A AR10102896 A AR 10102896A AR 010195 A1 AR010195 A1 AR 010195A1
- Authority
- AR
- Argentina
- Prior art keywords
- lower alkyl
- chnh
- alkyl
- unsaturated
- membered
- Prior art date
Links
- 229940116211 Vasopressin antagonist Drugs 0.000 title 1
- 239000003038 vasopressin antagonist Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 14
- 229910052760 oxygen Inorganic materials 0.000 abstract 4
- 229910052717 sulfur Inorganic materials 0.000 abstract 4
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000006615 aromatic heterocyclic group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- DQFQCHIDRBIESA-UHFFFAOYSA-N 1-benzazepine Chemical compound N1C=CC=CC2=CC=CC=C12 DQFQCHIDRBIESA-UHFFFAOYSA-N 0.000 abstract 1
- 125000002373 5 membered heterocyclic group Chemical group 0.000 abstract 1
- 125000004070 6 membered heterocyclic group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
- A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Reproductive Health (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Antagonistas de bvasopresina de benzacepina tricíclos que se seleccionan entre los de la formula I, donde E-Y se selecciono de las porciones -CH=CH-,-CH2-NR6-, -CH2-CH2- y cunado Y es -CH2-CH2- y cuando Y es -CH2-, Eestá seleccionado dela s porciones: >C=O alquilo inferior (C1-C6)-CHO, -CHOH,alquiloinferior (C1-C6)-CH-S, CHNH2, alquilo inferior (C1-C6)-CHN, C(N-alquilo inferior (C1-C6))2 o de formula II, -CHOCO- alquilo inferior C1-6, -CHNH (CH2)mNH2;-CHNH(CH2)m-NH-alquiloinf erior C1-6,-CHNH(CH2)m-N(alquilo inferior C1-6)2; -CHNH(CH2)m-S-alquilo inferior C1-6, -CHNH(CH2)m-O-alquilo inferior C1-6, -COHalquilo inferior C1-5,S,O,-NH,-N-alquilo inferior C1-6,-NCO-alquilo inferior C1-6;m es un entero de 1 a 6 y laporcion cíclica Z representa (1) un anilloaromático heterocílico insaturado, fusionado de 6 miembros que contiene dos átomos de nitrogeno,que está opcionalmente substituido con 1 o 2 substituyentesseleccionados de alquilo inferior C1-3,halogeno, amino, alcoxi inferior C1-3 o alquilamino inferior (C1-C3); (2) un anillo heterocíclico aromático(insaturado) fusionado de 5 miembros que tiene un heteroátomo que está seleccionado de O, N o S; (3) un anillo heterocíclicoaromático (insaturado) d e5 miembros que tiene dos átomos de nitrogeno; (4) un anillo heterocíclico aromático (insaturado) de 5 miembros que tiene un átomo de nitrogenoconjuntamente con un oxígeno o con un átomo de azufre, en el que losanillos heterocíclicos de 5 o 6 miembros están opcionalmente substituidos con alquiloinferior (C1-C3), halogeno o alcoxi inferior (C1-C3); R3 es -COAr, donde Ar es una porcion que está seleccionada del grupo que consiste en formula III, dondeXestá seleccionad de O, S, -NH, -NC H3 y -NCOCH3; R4 está seleccionado de Hidrogeno, alquilo inferior (C1-C3)-CO-alquilo inferior (C1-C3), o de Formula
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/373,839 US5696112A (en) | 1995-01-17 | 1995-01-17 | Fused heterocyclic azepines as vasopressin antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR010195A1 true AR010195A1 (es) | 2000-06-07 |
Family
ID=23474102
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP960101028A AR010195A1 (es) | 1995-01-17 | 1996-01-15 | Antagonistas de vasopresina de benzacepina triciclicos y procedimiento para su preparacion. |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US5696112A (es) |
| EP (1) | EP0811008B1 (es) |
| JP (1) | JPH10512572A (es) |
| KR (1) | KR19980703098A (es) |
| CN (1) | CN1177356A (es) |
| AR (1) | AR010195A1 (es) |
| AT (1) | ATE251166T1 (es) |
| AU (1) | AU716008B2 (es) |
| BR (1) | BR9607153A (es) |
| CA (1) | CA2210571A1 (es) |
| CZ (1) | CZ224697A3 (es) |
| DE (1) | DE69630209T2 (es) |
| DK (1) | DK0811008T3 (es) |
| EA (1) | EA001427B1 (es) |
| ES (1) | ES2207672T3 (es) |
| HU (1) | HUP9800466A3 (es) |
| IL (1) | IL116776A (es) |
| MX (1) | MX9705312A (es) |
| NZ (1) | NZ302119A (es) |
| PT (1) | PT811008E (es) |
| TW (1) | TW342385B (es) |
| WO (1) | WO1996022294A1 (es) |
| ZA (1) | ZA96298B (es) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU7338796A (en) * | 1995-11-09 | 1997-05-29 | Japan Tobacco Inc. | Five-membered fused heterocyclic azepine derivatives and pharmaceutical use thereof |
| US6297234B1 (en) | 1999-02-04 | 2001-10-02 | American Home Products Corporation | Arylthiophene vasopressin agonists |
| US6235900B1 (en) | 1999-02-04 | 2001-05-22 | American Home Products Corporation | Tricyclic pyridine N-oxides vasopressin agonists |
| US6437006B1 (en) | 1999-09-27 | 2002-08-20 | American Cyanamid Company | Pharmaceutical carrier formulation |
| US7022699B2 (en) | 2001-04-12 | 2006-04-04 | Wyeth | Cyclohexenyl phenyl diazepines vasopressin and oxytocin receptor modulators |
| US7326700B2 (en) * | 2001-04-12 | 2008-02-05 | Wyeth | Cyclohexenyl phenyl carboxamides tocolytic oxytocin receptor antagonists |
| US6903091B2 (en) * | 2001-04-12 | 2005-06-07 | Wyeth | Biphenyl vasopressin agonists |
| US7202239B2 (en) * | 2001-04-12 | 2007-04-10 | Wyeth | Cyclohexylphenyl carboxamides tocolytic oxytocin receptor antagonists |
| JP2004526771A (ja) | 2001-04-12 | 2004-09-02 | ワイス | シクロヘキシルフェニルバソプレッシンアゴニスト |
| US6977254B2 (en) * | 2001-04-12 | 2005-12-20 | Wyeth | Hydroxy cyclohexenyl phenyl carboxamides tocolytic oxytocin receptor antagonists |
| US7109193B2 (en) | 2001-04-12 | 2006-09-19 | Wyeth | Tricyclic diazepines tocolytic oxytocin receptor antagonists |
| US7064120B2 (en) * | 2001-04-12 | 2006-06-20 | Wyeth | Tricyclic pyridyl carboxamides and derivatives thereof tocolytic oxytocin receptor antagonists |
| US6900200B2 (en) | 2001-04-12 | 2005-05-31 | Wyeth | Tricyclic hydroxy carboxamides and derivatives thereof tocolytic oxytocin receptor antagonists |
| SE0102299D0 (sv) | 2001-06-26 | 2001-06-26 | Astrazeneca Ab | Compounds |
| SE0102764D0 (sv) | 2001-08-17 | 2001-08-17 | Astrazeneca Ab | Compounds |
| EP1632494A1 (en) * | 2004-08-24 | 2006-03-08 | Ferring B.V. | Vasopressin v1a antagonists |
| JP4651714B2 (ja) | 2005-07-09 | 2011-03-16 | アストラゼネカ アクチボラグ | 糖尿病の治療においてｇｌｋ活性化剤として使用するためのヘテロアリールベンズアミド誘導体 |
| EP1979335A2 (en) * | 2006-01-18 | 2008-10-15 | F.Hoffmann-La Roche Ag | Thiazoles as 11 beta-hsd1 inhibitors |
| EP2403860B1 (en) * | 2009-03-04 | 2015-11-04 | IDENIX Pharmaceuticals, Inc. | Phosphothiophene and phosphothiazole as hcv polymerase inhibitors |
| AR076221A1 (es) | 2009-04-09 | 2011-05-26 | Astrazeneca Ab | Derivado de pirazol [4,5-e] pirimidina y su uso para tratar diabetes y obesidad |
| WO2017175000A1 (en) | 2016-04-08 | 2017-10-12 | Pulmocide Limited | Compounds |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA821020B (en) * | 1981-02-18 | 1983-10-26 | Thomae Gmbh Dr K | Azepine derivatives, process for their preparation and pharmaceutical compositions thereof |
| US4766108A (en) * | 1986-12-04 | 1988-08-23 | Smith Kline Beckman Corporation | Tyr-Arg-vasopressin antagonists |
| US5055448A (en) * | 1987-06-25 | 1991-10-08 | Medical College Of Ohio | Linear derivatives of arginine vasopressin antagonists |
| DK0382185T3 (da) * | 1989-02-10 | 1994-07-04 | Otsuka Pharma Co Ltd | Carbostyrilderivater |
| KR0167349B1 (ko) * | 1989-10-20 | 1999-02-18 | 오스카 아끼히꼬 | 벤조헤테로 고리 화합물 |
| US5258510A (en) * | 1989-10-20 | 1993-11-02 | Otsuka Pharma Co Ltd | Benzoheterocyclic compounds |
| US5070187A (en) * | 1989-11-03 | 1991-12-03 | Trustees Of Boston University | Pharmacologically effective antagonists of arginine-vasopressin |
| TW199153B (es) * | 1990-08-07 | 1993-02-01 | Dtsuka Seiyaku Kk | |
| CA2066104C (en) * | 1991-04-19 | 2003-05-27 | Hidenori Ogawa | Benzazepine derivatives as vasopressin antagonists |
| DE69223573D1 (de) * | 1991-09-16 | 1998-01-29 | Merck & Co Inc | Hydantoin und Succinimid-substituierte Spiroindanylcamphorsulfonyl als Oxytocin-Antagonisten |
| EP0533240A3 (en) * | 1991-09-16 | 1993-09-29 | Merck & Co. Inc. | Substituted amine derivatives of piperazinylcamphorsulfonyl oxytocin antagonists |
| EP0533242A3 (en) * | 1991-09-16 | 1993-09-15 | Merck & Co. Inc. | Substituted derivatives of piperazinylcamphorsulfonyl oxytocin antagonists |
| US5204349A (en) * | 1991-09-16 | 1993-04-20 | Merck & Co., Inc. | Amide-substituted derivatives of spiroindanylcamphorsulfonyl oxytocin antagonists |
| WO1994004525A1 (en) * | 1992-08-20 | 1994-03-03 | Otsuka Pharmaceutical Company, Limited | Benzoheterocyclic compounds as oxytocin and vasopressin antagonists |
| TW270927B (es) * | 1992-10-16 | 1996-02-21 | Otsuka Pharma Co Ltd | |
| WO1994012476A1 (fr) * | 1992-11-25 | 1994-06-09 | Yamanouchi Pharmaceutical Co., Ltd. | Derive de benzanilide |
| WO1994014796A1 (fr) * | 1992-12-21 | 1994-07-07 | Yamanouchi Pharmaceutical Co., Ltd. | Nouveau derive de n-(pyridylcarbonyl)benzazepine et son intermediaire |
| WO1994020473A1 (fr) * | 1993-03-11 | 1994-09-15 | Yamanouchi Pharmaceutical Co., Ltd. | Compose avec action antagoniste de la vasopressine |
| GB9307527D0 (en) * | 1993-04-13 | 1993-06-02 | Fujisawa Pharmaceutical Co | New venzamide derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same |
-
1995
- 1995-01-17 US US08/373,839 patent/US5696112A/en not_active Expired - Lifetime
- 1995-06-02 US US08/460,418 patent/US5654297A/en not_active Expired - Lifetime
-
1996
- 1996-01-15 AR ARP960101028A patent/AR010195A1/es not_active Application Discontinuation
- 1996-01-15 ZA ZA96298A patent/ZA96298B/xx unknown
- 1996-01-16 JP JP8522453A patent/JPH10512572A/ja not_active Ceased
- 1996-01-16 MX MX9705312A patent/MX9705312A/es not_active IP Right Cessation
- 1996-01-16 WO PCT/US1996/001096 patent/WO1996022294A1/en not_active Ceased
- 1996-01-16 CN CN96192356A patent/CN1177356A/zh active Pending
- 1996-01-16 EP EP96903711A patent/EP0811008B1/en not_active Expired - Lifetime
- 1996-01-16 CA CA002210571A patent/CA2210571A1/en not_active Abandoned
- 1996-01-16 NZ NZ302119A patent/NZ302119A/en unknown
- 1996-01-16 AU AU47706/96A patent/AU716008B2/en not_active Ceased
- 1996-01-16 EA EA199700115A patent/EA001427B1/ru not_active IP Right Cessation
- 1996-01-16 BR BR9607153A patent/BR9607153A/pt unknown
- 1996-01-16 DE DE69630209T patent/DE69630209T2/de not_active Expired - Fee Related
- 1996-01-16 KR KR1019970704946A patent/KR19980703098A/ko not_active Ceased
- 1996-01-16 ES ES96903711T patent/ES2207672T3/es not_active Expired - Lifetime
- 1996-01-16 PT PT96903711T patent/PT811008E/pt unknown
- 1996-01-16 IL IL11677696A patent/IL116776A/xx not_active IP Right Cessation
- 1996-01-16 CZ CZ972246A patent/CZ224697A3/cs unknown
- 1996-01-16 TW TW085100460A patent/TW342385B/zh active
- 1996-01-16 DK DK96903711T patent/DK0811008T3/da active
- 1996-01-16 HU HU9800466A patent/HUP9800466A3/hu unknown
- 1996-01-16 AT AT96903711T patent/ATE251166T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CZ224697A3 (cs) | 1998-01-14 |
| AU4770696A (en) | 1996-08-07 |
| DE69630209T2 (de) | 2004-08-19 |
| MX9705312A (es) | 1997-10-31 |
| BR9607153A (pt) | 1997-11-11 |
| TW342385B (en) | 1998-10-11 |
| EP0811008A1 (en) | 1997-12-10 |
| KR19980703098A (ko) | 1998-10-15 |
| EA199700115A1 (ru) | 1997-12-30 |
| NZ302119A (en) | 2000-02-28 |
| HUP9800466A2 (hu) | 1998-07-28 |
| ZA96298B (en) | 1997-07-15 |
| EA001427B1 (ru) | 2001-02-26 |
| HUP9800466A3 (en) | 1998-12-28 |
| WO1996022294A1 (en) | 1996-07-25 |
| IL116776A (en) | 2000-10-31 |
| US5696112A (en) | 1997-12-09 |
| PT811008E (pt) | 2004-02-27 |
| DE69630209D1 (de) | 2003-11-06 |
| AU716008B2 (en) | 2000-02-17 |
| CN1177356A (zh) | 1998-03-25 |
| ATE251166T1 (de) | 2003-10-15 |
| ES2207672T3 (es) | 2004-06-01 |
| US5654297A (en) | 1997-08-05 |
| JPH10512572A (ja) | 1998-12-02 |
| CA2210571A1 (en) | 1996-07-25 |
| IL116776A0 (en) | 1996-05-14 |
| DK0811008T3 (da) | 2004-01-26 |
| EP0811008B1 (en) | 2003-10-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |