AR002914A1 - A CHEMICALLY INDUCTIBLE GENE EXPRESSION CASSSETTE FOR VEGETABLES THAT INCLUDES A SEQUENCE THAT CODES AN INSECTICIDE PROTEIN, A VEGETABLE CELL, A PLANTS AND SEEDS TRANSFORMED WITH THE CASSETTE, A METHOD OF CONTROLLING INSECTS. - Google Patents
A CHEMICALLY INDUCTIBLE GENE EXPRESSION CASSSETTE FOR VEGETABLES THAT INCLUDES A SEQUENCE THAT CODES AN INSECTICIDE PROTEIN, A VEGETABLE CELL, A PLANTS AND SEEDS TRANSFORMED WITH THE CASSETTE, A METHOD OF CONTROLLING INSECTS.Info
- Publication number
- AR002914A1 AR002914A1 ARP960103689A AR10368996A AR002914A1 AR 002914 A1 AR002914 A1 AR 002914A1 AR P960103689 A ARP960103689 A AR P960103689A AR 10368996 A AR10368996 A AR 10368996A AR 002914 A1 AR002914 A1 AR 002914A1
- Authority
- AR
- Argentina
- Prior art keywords
- cassette
- plant
- gene
- chemically
- gene expression
- Prior art date
Links
- 241000238631 Hexapoda Species 0.000 title abstract 4
- 230000014509 gene expression Effects 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 235000013311 vegetables Nutrition 0.000 title 2
- 239000002917 insecticide Substances 0.000 title 1
- 230000001939 inductive effect Effects 0.000 abstract 3
- 102000034356 gene-regulatory proteins Human genes 0.000 abstract 2
- 108091006104 gene-regulatory proteins Proteins 0.000 abstract 2
- 239000000411 inducer Substances 0.000 abstract 2
- 108700001094 Plant Genes Proteins 0.000 abstract 1
- 101150053489 alcR gene Proteins 0.000 abstract 1
- 230000001276 controlling effect Effects 0.000 abstract 1
- 230000037353 metabolic pathway Effects 0.000 abstract 1
- 239000002207 metabolite Substances 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 230000009466 transformation Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8237—Externally regulated expression systems
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8237—Externally regulated expression systems
- C12N15/8238—Externally regulated expression systems chemically inducible, e.g. tetracycline
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
- Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
Landscapes
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Insects & Arthropods (AREA)
- Pest Control & Pesticides (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Peptides Or Proteins (AREA)
Abstract
Un cassette de expresión génica para vegetales inducible químicamente que comprende un primer promotor ligado operativamente a una secuencia reguladoraderivada del gen alcR y que codifica una proteína reguladora, y un promotor inducible ligadooperativamente a un gen de interés que codifica una proteinadanina para insectos o cuya expresión induce una vía metabólica productora de un metabolito danino para insectos, con dicho promotor inducible activado porla proteina reguladora en presencia de un inductor exógeno efectivo por medio del cual la aplicación del inductor provoca la expresión del gen de interés. Lainvención también se refiere a una célula vegetal que contiene dicho cassette; un tejido vegetal y una planta que comprendela célula vegetal; una semilla quederiva de la planta y un método para controlar insectos que comprende la transformación de una célula vegetal.A chemically inducible plant gene expression cassette comprising a first promoter operably linked to a regulatory sequence derived from the alcR gene and encoding a regulatory protein, and an inducible promoter operatively linked to a gene of interest that encodes a protein proteinadanine for insects or whose expression induces a metabolic pathway producing a harmful metabolite for insects, with said inducible promoter activated by the regulatory protein in the presence of an effective exogenous inducer by means of which the application of the inducer causes the expression of the gene of interest. The invention also refers to a plant cell containing said cassette; a plant tissue and a plant comprising the plant cell; a seed derived from the plant and a method for controlling insects that involves the transformation of a plant cell.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9516241.8A GB9516241D0 (en) | 1995-08-08 | 1995-08-08 | Dna constructs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR002914A1 true AR002914A1 (en) | 1998-04-29 |
Family
ID=10778942
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP960103689A AR002914A1 (en) | 1995-08-08 | 1996-07-22 | A CHEMICALLY INDUCTIBLE GENE EXPRESSION CASSSETTE FOR VEGETABLES THAT INCLUDES A SEQUENCE THAT CODES AN INSECTICIDE PROTEIN, A VEGETABLE CELL, A PLANTS AND SEEDS TRANSFORMED WITH THE CASSETTE, A METHOD OF CONTROLLING INSECTS. |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0846179A2 (en) |
| JP (1) | JPH11510694A (en) |
| KR (1) | KR19990036251A (en) |
| CN (1) | CN1199425A (en) |
| AP (1) | AP863A (en) |
| AR (1) | AR002914A1 (en) |
| AU (1) | AU704172B2 (en) |
| BR (1) | BR9609873A (en) |
| CA (1) | CA2227445A1 (en) |
| CZ (1) | CZ36998A3 (en) |
| GB (1) | GB9516241D0 (en) |
| HU (1) | HUP9900057A3 (en) |
| IL (1) | IL123172A0 (en) |
| MX (1) | MX9801008A (en) |
| NZ (1) | NZ313724A (en) |
| PL (1) | PL324880A1 (en) |
| SK (1) | SK16998A3 (en) |
| TR (1) | TR199800177T1 (en) |
| WO (1) | WO1997006268A2 (en) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9606062D0 (en) | 1996-03-22 | 1996-05-22 | Zeneca Ltd | Promoters |
| GB9817704D0 (en) * | 1998-08-13 | 1998-10-07 | Zeneca Ltd | Gene switch |
| GB9902236D0 (en) * | 1999-02-01 | 1999-03-24 | Zeneca Ltd | Formulation |
| GB9902234D0 (en) * | 1999-02-01 | 1999-03-24 | Zeneca Ltd | Expression system |
| GB9918154D0 (en) * | 1999-08-02 | 1999-10-06 | Zeneca Ltd | Expression system |
| EP1925672A1 (en) | 2001-06-22 | 2008-05-28 | Syngeta Participations AG | Abiotic stress responsive polynucleotides and polypeptides |
| DE10212158A1 (en) | 2002-03-19 | 2003-10-02 | Metanomics Gmbh & Co Kgaa | Population of transgenic plants, derived biological material, corresponding plasmid collection and population of transformed host organisms, as well as their use and methods for their production |
| EP1578975A2 (en) | 2002-12-20 | 2005-09-28 | Metanomics GmbH & Co. KGaA | Method for producing aminoacids |
| BRPI0407514A (en) | 2003-02-17 | 2006-02-14 | Metanomics Gmbh | method for preparing a non-human organism, polynucleotide, method for preparing a vector, vector, host cell, polypeptide, antibody, antisense polynucleic acid, method for preparing a plant, plant cell, transgenic plant tissue, useful animal cell , useful animal or a transgenic microorganism non-human organism, transgenic microorganism, yield or a propagating material of a useful plant or animal, biomass of a microorganism, method for preparing fine chemicals, and, use of polypeptide |
| WO2005014828A2 (en) | 2003-08-01 | 2005-02-17 | Basf Plant Science Gmbh | Process for the production of fine chemicals in plants |
| WO2008015263A2 (en) | 2006-08-02 | 2008-02-07 | Cropdesign N.V. | Plants having improved characteristics and a method for making the same |
| AU2005321630A1 (en) | 2004-07-02 | 2006-07-06 | Metanomics Gmbh | Process for the production of fine chemicals |
| CA2575127A1 (en) | 2004-07-31 | 2006-02-09 | Metanomics Gmbh | Preparation of organisms with faster growth and/or higher yield |
| MX2007007040A (en) | 2004-12-17 | 2008-10-24 | Metanomics Gmbh | Process for the control of production of fine chemicals. |
| EP2573188A2 (en) | 2005-03-02 | 2013-03-27 | Metanomics GmbH | Process for the production of fine chemicals |
| WO2006092449A2 (en) | 2005-03-02 | 2006-09-08 | Metanomics Gmbh | Process for the production of fine chemicals |
| WO2006094976A2 (en) | 2005-03-08 | 2006-09-14 | Basf Plant Science Gmbh | Expression enhancing intron sequences |
| AR054161A1 (en) | 2005-07-06 | 2007-06-06 | Cropdesign Nv | PLANTS WITH INCREASED PERFORMANCE AND A METHOD FOR PREPARING THEM |
| EP2573179A1 (en) | 2005-09-15 | 2013-03-27 | CropDesign N.V. | Plants having increased yield and method for making the same |
| CA2638978A1 (en) | 2006-03-31 | 2007-10-11 | Basf Plant Science Gmbh | Plants having enhanced yield-related traits and a method for making the same |
| CA2644273A1 (en) | 2006-04-05 | 2008-03-27 | Metanomics Gmbh | Process for the production of a fine chemical |
| CN101460517B (en) | 2006-05-31 | 2013-11-06 | 梅坦诺米克斯有限公司 | Manipulation of nitrogen metabolism using ammonium transporters or glucose-6-phosphate dehydrogenase or farnesyl phosphate synthase (FPP) |
| WO2007141189A2 (en) | 2006-06-08 | 2007-12-13 | Basf Plant Science Gmbh | Plants having improved growth characteristics and method for making the same |
| ITUD20060280A1 (en) | 2006-12-29 | 2008-06-30 | Univ Degli Studi Udine | ARTIFICIAL SEQUENCE OF DNA EVENT FUNCTION OF LEADER IN 5 '(5'-UTR) OPTIMIZED FOR THE OVEREXPRESSION OF HETEROLOGICAL PLANT PROTEINS |
| EP2152888A2 (en) | 2007-05-04 | 2010-02-17 | BASF Plant Science GmbH | Enhancement of seed oil / amino acid content by combinations of pyruvate kinase subunits |
| CN101765660B (en) | 2007-05-22 | 2013-10-23 | 巴斯夫植物科学有限公司 | Plant cells and plants with increased tolerance and/or resistance to environmental stress and increased biomass production |
| DK2219469T3 (en) | 2007-12-03 | 2017-11-20 | Syngenta Participations Ag | MODIFICATION OF ENZYMATICALLY DISPOSED PROTEINS |
| WO2009080743A2 (en) | 2007-12-21 | 2009-07-02 | Basf Plant Science Gmbh | Plants with increased yield (ko nue) |
| WO2011074959A1 (en) | 2009-12-15 | 2011-06-23 | Edwin Henricus Antonius Holman | Transgenic ozone-resistant plants |
| AR083029A1 (en) | 2010-12-09 | 2013-01-23 | Syngenta Participations Ag | METHODS AND COMPOSITIONS THAT USE SMALL INTERFERENT ARN (ARNIP) FOR THE CONTROL OF NEMATODES IN PLANTS |
| CA2825388A1 (en) | 2011-01-18 | 2012-07-26 | Syngenta Participations Ag | Methods and compositions for modified ethanol inducible promoter systems |
| EP2768950B1 (en) | 2011-10-20 | 2018-03-07 | University of Iowa Research Foundation | N-demethyase genes and uses thereof |
| ES2670505T3 (en) | 2012-02-16 | 2018-05-30 | Syngenta Participations Ag | Modified Pesticide Proteins |
| WO2013187957A1 (en) | 2012-06-15 | 2013-12-19 | University Of Iowa Research Foundation | Caffeine responsive promoters and regulatory genes |
| MX370669B (en) | 2012-06-22 | 2019-12-19 | Syngenta Participations Ag | Biological control of coleopteran pests. |
| US9816102B2 (en) | 2012-09-13 | 2017-11-14 | Indiana University Research And Technology Corporation | Compositions and systems for conferring disease resistance in plants and methods of use thereof |
| CA2948369C (en) | 2014-04-17 | 2023-09-26 | Boehringer Ingelheim Rcv Gmbh & Co Kg | Recombinant host cell engineered to overexpress helper proteins |
| AU2015248807B2 (en) | 2014-04-17 | 2021-07-22 | Boehringer Ingelheim Rcv Gmbh & Co Kg | Recombinant host cell for expressing proteins of interest |
| EP2952584A1 (en) | 2014-06-04 | 2015-12-09 | Boehringer Ingelheim RCV GmbH & Co KG | Improved protein production |
| WO2016100333A1 (en) | 2014-12-15 | 2016-06-23 | Syngenta Participations Ag | Pesticidal microrna carriers and use thereof |
| CA2969105A1 (en) | 2014-12-23 | 2016-06-30 | Syngenta Participations Ag | Biological control of coleopteran pests |
| JP6937699B2 (en) | 2015-04-10 | 2021-09-22 | シンジェンタ パーティシペーションズ アーゲー | Animal feed composition and usage |
| WO2018076335A1 (en) | 2016-10-31 | 2018-05-03 | Institute Of Genetics And Developmental Biology, Chinese Academy Of Sciences | Compositions and methods for enhancing abiotic stress tolerance |
| US11479798B2 (en) | 2017-03-29 | 2022-10-25 | Boehringer Ingelheim Rcv Gmbh & Co Kg | Recombinant host cell with altered membrane lipid composition |
| KR20250002850A (en) | 2017-05-01 | 2025-01-07 | 신젠타 크롭 프로텍션 아게 | Animal feed compositions and methods of use |
| WO2018213771A1 (en) | 2017-05-18 | 2018-11-22 | Cargill, Incorporated | Genome editing system |
| CN111148432B (en) | 2017-10-02 | 2021-11-23 | 先正达参股股份有限公司 | Engineered pesticidal proteins and methods of controlling plant pests |
| US11905518B2 (en) | 2018-02-12 | 2024-02-20 | Curators Of The University Of Missouri | Small auxin upregulated (SAUR) gene for the improvement of root system architecture, waterlogging tolerance, drought resistance and yield in plants and methods of uses |
| AU2020226376A1 (en) | 2019-02-20 | 2021-08-05 | Syngenta Crop Protection Ag | Engineered pesticidal proteins and methods of controlling plant pests |
| AU2022220827A1 (en) | 2021-02-12 | 2023-09-21 | Boehringer Ingelheim Rcv Gmbh & Co Kg | Signal peptides for increased protein secretion |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5447858A (en) * | 1984-04-13 | 1995-09-05 | Mycogen Plant Sciences, Inc. | Heat shock promoter and gene |
| UA48104C2 (en) * | 1991-10-04 | 2002-08-15 | Новартіс Аг | Dna fragment including sequence that codes an insecticide protein with optimization for corn, dna fragment providing directed preferable for the stem core expression of the structural gene of the plant related to it, dna fragment providing specific for the pollen expression of related to it structural gene in the plant, recombinant dna molecule, method for obtaining a coding sequence of the insecticide protein optimized for corn, method of corn plants protection at least against one pest insect |
| DK0637339T3 (en) * | 1992-04-13 | 2001-12-03 | Syngenta Ltd | DNA constructs and plants in which they are incorporated |
| DE69434624T2 (en) * | 1993-11-19 | 2006-12-14 | Biotechnology Research And Development Corp., Peoria | CHIMERIC REGULATORY REGIONS AND GENE CASSETTES FOR GENE EXPRESSION IN PLANTS |
-
1995
- 1995-08-08 GB GBGB9516241.8A patent/GB9516241D0/en active Pending
-
1996
- 1996-07-22 AR ARP960103689A patent/AR002914A1/en unknown
- 1996-07-29 KR KR1019980700919A patent/KR19990036251A/en not_active Ceased
- 1996-07-29 PL PL96324880A patent/PL324880A1/en unknown
- 1996-07-29 BR BR9609873A patent/BR9609873A/en not_active Application Discontinuation
- 1996-07-29 JP JP9508208A patent/JPH11510694A/en active Pending
- 1996-07-29 MX MX9801008A patent/MX9801008A/en unknown
- 1996-07-29 CZ CZ98369A patent/CZ36998A3/en unknown
- 1996-07-29 AP APAP/P/1998/001194A patent/AP863A/en active
- 1996-07-29 AU AU66252/96A patent/AU704172B2/en not_active Ceased
- 1996-07-29 IL IL12317296A patent/IL123172A0/en unknown
- 1996-07-29 NZ NZ313724A patent/NZ313724A/en unknown
- 1996-07-29 WO PCT/GB1996/001846 patent/WO1997006268A2/en not_active Ceased
- 1996-07-29 CA CA002227445A patent/CA2227445A1/en not_active Abandoned
- 1996-07-29 HU HU9900057A patent/HUP9900057A3/en unknown
- 1996-07-29 CN CN96197496A patent/CN1199425A/en active Pending
- 1996-07-29 SK SK169-98A patent/SK16998A3/en unknown
- 1996-07-29 EP EP96925889A patent/EP0846179A2/en not_active Withdrawn
- 1996-07-29 TR TR1998/00177T patent/TR199800177T1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR19990036251A (en) | 1999-05-25 |
| HUP9900057A2 (en) | 1999-04-28 |
| AP863A (en) | 2000-08-04 |
| AU6625296A (en) | 1997-03-05 |
| AP9801194A0 (en) | 1998-03-31 |
| GB9516241D0 (en) | 1995-10-11 |
| SK16998A3 (en) | 1998-09-09 |
| TR199800177T1 (en) | 1998-05-21 |
| AU704172B2 (en) | 1999-04-15 |
| WO1997006268A2 (en) | 1997-02-20 |
| JPH11510694A (en) | 1999-09-21 |
| WO1997006268A3 (en) | 1997-03-13 |
| EP0846179A2 (en) | 1998-06-10 |
| CN1199425A (en) | 1998-11-18 |
| HUP9900057A3 (en) | 2001-06-28 |
| NZ313724A (en) | 1999-04-29 |
| BR9609873A (en) | 1999-03-23 |
| CA2227445A1 (en) | 1997-02-20 |
| MX9801008A (en) | 1998-04-30 |
| CZ36998A3 (en) | 1998-06-17 |
| IL123172A0 (en) | 1998-09-24 |
| PL324880A1 (en) | 1998-06-22 |
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