AR002359A1 - Procedimiento para la hidrogenacion de iminas. - Google Patents
Procedimiento para la hidrogenacion de iminas.Info
- Publication number
- AR002359A1 AR002359A1 ARP960102994A AR10299496A AR002359A1 AR 002359 A1 AR002359 A1 AR 002359A1 AR P960102994 A ARP960102994 A AR P960102994A AR 10299496 A AR10299496 A AR 10299496A AR 002359 A1 AR002359 A1 AR 002359A1
- Authority
- AR
- Argentina
- Prior art keywords
- hydrogenation
- iminas
- procedure
- imines
- hydrogen
- Prior art date
Links
- 238000005984 hydrogenation reaction Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 abstract 1
- 150000002466 imines Chemical class 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 229910052741 iridium Inorganic materials 0.000 abstract 1
- GKOZUEZYRPOHIO-UHFFFAOYSA-N iridium atom Chemical compound [Ir] GKOZUEZYRPOHIO-UHFFFAOYSA-N 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/44—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers
- C07C209/52—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of imines or imino-ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/08—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/88—Carboxylic acid amides having nitrogen atoms of carboxamide groups bound to an acyclic carbon atom and to a carbon atom of a six-membered aromatic ring wherein at least one ortho-hydrogen atom has been replaced
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/36—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
Abstract
Procedimiento para la hidrogenación de iminas con hidrógeno a presión elevada en presencia de catalizadores de iridio y con o sin agente disolventeinerte, caracterizado porque la mezcla de reacción contiene hidruro de iodo.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH168595 | 1995-06-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR002359A1 true AR002359A1 (es) | 1998-03-11 |
Family
ID=4216210
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP960102994A AR002359A1 (es) | 1995-06-08 | 1996-06-06 | Procedimiento para la hidrogenacion de iminas. |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US5886225A (es) |
| EP (1) | EP0830337B1 (es) |
| JP (1) | JP4128623B2 (es) |
| KR (1) | KR100470884B1 (es) |
| CN (1) | CN1176900C (es) |
| AR (1) | AR002359A1 (es) |
| AT (1) | ATE187957T1 (es) |
| AU (1) | AU710870B2 (es) |
| BR (1) | BR9609159A (es) |
| CA (1) | CA2220999C (es) |
| CZ (1) | CZ287315B6 (es) |
| DE (1) | DE69605794T2 (es) |
| DK (1) | DK0830337T3 (es) |
| EA (1) | EA000498B1 (es) |
| ES (1) | ES2141512T3 (es) |
| GR (1) | GR3032521T3 (es) |
| HR (1) | HRP960253B1 (es) |
| HU (1) | HU229337B1 (es) |
| IL (1) | IL122184A (es) |
| PL (1) | PL183317B1 (es) |
| PT (1) | PT830337E (es) |
| SK (1) | SK281568B6 (es) |
| TW (1) | TW346482B (es) |
| UA (1) | UA51652C2 (es) |
| WO (1) | WO1996041793A1 (es) |
| ZA (1) | ZA964832B (es) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0691949B1 (en) * | 1994-02-02 | 1998-10-14 | Novartis AG | Process for the hydrogenation of imines |
| US6228971B1 (en) * | 1999-06-21 | 2001-05-08 | Ppg Industries Ohio, Inc. | Polymeric imine functional compositions and their use in film-forming compositions |
| US20070213540A1 (en) * | 2006-03-09 | 2007-09-13 | Degussa Ag | Process for the hydrogenation of imines |
| US8268872B2 (en) | 2008-02-22 | 2012-09-18 | Radius Health, Inc. | Selective androgen receptor modulators |
| US8067448B2 (en) | 2008-02-22 | 2011-11-29 | Radius Health, Inc. | Selective androgen receptor modulators |
| WO2011097496A1 (en) | 2010-02-04 | 2011-08-11 | Radius Health, Inc. | Selective androgen receptor modulators |
| MX342898B (es) | 2010-05-12 | 2016-10-18 | Radius Health Inc * | Regimen terapéutico de la sal de diclorhidrato del (r) -6-(2-(etil (4-2(etilamino) etil) bencil) amino)-4-metoxifenil)-5, 6,7,8-tetrahidronaftaleno-2-ol. |
| US8642632B2 (en) | 2010-07-02 | 2014-02-04 | Radius Health, Inc. | Selective androgen receptor modulators |
| ES2550319T3 (es) | 2010-09-28 | 2015-11-06 | Radius Health, Inc | Moduladores selectivos del receptor de andrógenos |
| CN102153589B (zh) | 2011-02-28 | 2013-01-02 | 大连多相触媒有限公司 | 一种亚胺的不对称加氢催化剂及其合成方法和应用 |
| WO2014037962A1 (en) | 2012-09-06 | 2014-03-13 | Council Of Scientific And Industrial Research | Process for the preparation of (s)-2-ethyl-n-(1-methoxypropan -2-yl)-6-methyl aniline |
| SI3122426T1 (sl) | 2014-03-28 | 2023-04-28 | Duke University | Zdravljenje raka dojk z uporabo selektivnih modulatorjev estrogenskih receptorjev |
| US9421264B2 (en) | 2014-03-28 | 2016-08-23 | Duke University | Method of treating cancer using selective estrogen receptor modulators |
| CA3027563C (en) | 2016-06-22 | 2024-07-02 | Ellipses Pharma Ltd | AR+ METHODS FOR BREAST CANCER TREATMENT |
| ES2981967T3 (es) | 2017-01-05 | 2024-10-14 | Radius Pharmaceuticals Inc | Formas polimórficas de RAD1901-2HCl |
| WO2020010216A1 (en) | 2018-07-04 | 2020-01-09 | Radius Pharmaceuticals, Inc. | Polymorphic forms of rad 1901-2hcl |
| PH12021551950A1 (en) | 2019-02-12 | 2022-05-23 | Radius Pharmaceuticals Inc | Processes and compounds |
| CN110305025B (zh) * | 2019-07-23 | 2022-05-06 | 衢州学院 | 一种由亚胺催化氢化合成苄胺类化合物的方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0256982B1 (de) * | 1986-08-04 | 1991-08-28 | Ciba-Geigy Ag | Verfahren zur Herstellung von optisch aktiven sekundären Arylaminen |
| US5011995A (en) * | 1987-07-28 | 1991-04-30 | Ciba-Geigy Corporation | Process for the preparation of optically active secondary amines |
| EP0419409B1 (de) * | 1989-09-18 | 1995-11-02 | Ciba-Geigy Ag | Iridiumkomplexe, Verfahren zu deren Herstellung und deren Verwendung |
| EP0564406B1 (de) * | 1992-04-02 | 1999-05-06 | Novartis AG | Ferrocenyldiphosphine als Liganden für homogene Katalysatoren |
| DE69512765T2 (de) * | 1994-02-02 | 2000-06-29 | Novartis Ag, Basel | Hydrierungskatalysator, verfahren zu seiner herstellung und hydrierungsverfahren |
-
1996
- 1996-04-06 UA UA97125857A patent/UA51652C2/uk unknown
- 1996-05-22 TW TW085106030A patent/TW346482B/zh not_active IP Right Cessation
- 1996-06-04 IL IL12218496A patent/IL122184A/xx not_active IP Right Cessation
- 1996-06-04 CN CNB96194661XA patent/CN1176900C/zh not_active Expired - Lifetime
- 1996-06-04 HU HU9802307A patent/HU229337B1/hu unknown
- 1996-06-04 ES ES96920786T patent/ES2141512T3/es not_active Expired - Lifetime
- 1996-06-04 AU AU62218/96A patent/AU710870B2/en not_active Expired
- 1996-06-04 CZ CZ19973919A patent/CZ287315B6/cs not_active IP Right Cessation
- 1996-06-04 CA CA002220999A patent/CA2220999C/en not_active Expired - Lifetime
- 1996-06-04 PT PT96920786T patent/PT830337E/pt unknown
- 1996-06-04 EA EA199700424A patent/EA000498B1/ru not_active IP Right Cessation
- 1996-06-04 WO PCT/EP1996/002419 patent/WO1996041793A1/en not_active Ceased
- 1996-06-04 EP EP96920786A patent/EP0830337B1/en not_active Expired - Lifetime
- 1996-06-04 KR KR1019970708383A patent/KR100470884B1/ko not_active Expired - Lifetime
- 1996-06-04 US US08/973,575 patent/US5886225A/en not_active Expired - Lifetime
- 1996-06-04 BR BR9609159A patent/BR9609159A/pt active IP Right Grant
- 1996-06-04 SK SK1681-97A patent/SK281568B6/sk not_active IP Right Cessation
- 1996-06-04 DE DE69605794T patent/DE69605794T2/de not_active Expired - Lifetime
- 1996-06-04 AT AT96920786T patent/ATE187957T1/de active
- 1996-06-04 PL PL96323946A patent/PL183317B1/pl unknown
- 1996-06-04 DK DK96920786T patent/DK0830337T3/da active
- 1996-06-04 JP JP50257997A patent/JP4128623B2/ja not_active Expired - Lifetime
- 1996-06-05 HR HR960253A patent/HRP960253B1/xx not_active IP Right Cessation
- 1996-06-06 AR ARP960102994A patent/AR002359A1/es active IP Right Grant
- 1996-06-07 ZA ZA964832A patent/ZA964832B/xx unknown
-
2000
- 2000-01-31 GR GR20000400217T patent/GR3032521T3/el unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |