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AR002270A1 - Clorhidrato de valaciclovir 2-[(2-amino-1,6-dihidro-6-oxo-9h-purin-9-il)metoxi]etil-l-valinato, uso para preparar un medicamento y proceso para obtener dicha forma cristalina - Google Patents

Clorhidrato de valaciclovir 2-[(2-amino-1,6-dihidro-6-oxo-9h-purin-9-il)metoxi]etil-l-valinato, uso para preparar un medicamento y proceso para obtener dicha forma cristalina

Info

Publication number
AR002270A1
AR002270A1 ARP960101082A AR10108296A AR002270A1 AR 002270 A1 AR002270 A1 AR 002270A1 AR P960101082 A ARP960101082 A AR P960101082A AR 10108296 A AR10108296 A AR 10108296A AR 002270 A1 AR002270 A1 AR 002270A1
Authority
AR
Argentina
Prior art keywords
purin
dihydro
oxo
ethyl
amino
Prior art date
Application number
ARP960101082A
Other languages
English (en)
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10768347&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR002270(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of AR002270A1 publication Critical patent/AR002270A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención se refiere a una forma cristalina anhidra de clorhidrato 2[-(2-amino-1,6-dihidro-6-oxo-purin-9-il)metoxi]etil L-valinato(conocido como clorhidrato de valaciclovir) y a un proceso para la elaboración del mismo.
ARP960101082A 1995-01-20 1996-01-19 Clorhidrato de valaciclovir 2-[(2-amino-1,6-dihidro-6-oxo-9h-purin-9-il)metoxi]etil-l-valinato, uso para preparar un medicamento y proceso para obtener dicha forma cristalina AR002270A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9501178.9A GB9501178D0 (en) 1995-01-20 1995-01-20 Guanine derivative

Publications (1)

Publication Number Publication Date
AR002270A1 true AR002270A1 (es) 1998-03-11

Family

ID=10768347

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP960101082A AR002270A1 (es) 1995-01-20 1996-01-19 Clorhidrato de valaciclovir 2-[(2-amino-1,6-dihidro-6-oxo-9h-purin-9-il)metoxi]etil-l-valinato, uso para preparar un medicamento y proceso para obtener dicha forma cristalina

Country Status (40)

Country Link
US (1) US6107302A (es)
EP (1) EP0804436B1 (es)
JP (1) JP3176633B2 (es)
KR (1) KR100376074B1 (es)
CN (1) CN1049893C (es)
AP (1) AP662A (es)
AR (1) AR002270A1 (es)
AT (1) ATE302777T1 (es)
AU (1) AU702794B2 (es)
BG (1) BG63393B1 (es)
BR (1) BR9606768A (es)
CA (1) CA2210799C (es)
CY (1) CY2531B1 (es)
CZ (1) CZ297065B6 (es)
DE (1) DE69635106T2 (es)
DK (1) DK0804436T3 (es)
EA (1) EA000364B1 (es)
EE (1) EE03528B1 (es)
ES (1) ES2248806T3 (es)
FI (1) FI973063L (es)
GB (1) GB9501178D0 (es)
GE (1) GEP20001940B (es)
HR (1) HRP960024B1 (es)
HU (1) HU222993B1 (es)
IL (1) IL116831A (es)
IN (1) IN182468B (es)
IS (1) IS2268B (es)
NO (1) NO315558B1 (es)
NZ (1) NZ298851A (es)
OA (1) OA10499A (es)
PL (1) PL182175B1 (es)
RO (1) RO118693B1 (es)
RS (1) RS49518B (es)
SI (1) SI0804436T1 (es)
SK (1) SK285329B6 (es)
TR (1) TR199700656T1 (es)
UA (1) UA46001C2 (es)
UY (1) UY25779A1 (es)
WO (1) WO1996022291A1 (es)
ZA (1) ZA96449B (es)

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US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
US20050043329A1 (en) * 2002-09-06 2005-02-24 Shlomit Wizel Crystalline forms of valacyclovir hydrochloride
US20050059684A1 (en) * 2002-10-16 2005-03-17 Ben-Zion Dolitzky Method for reducing residual alcohols in crystalline valacyclovir hydrochloride
WO2004035583A1 (en) * 2002-10-16 2004-04-29 Teva Pharmaceutical Industries Ltd. Method for reducing residual alcohols in crystalline valacyclovir hydrochloride
EP1575953A1 (en) * 2002-12-09 2005-09-21 Texcontor Etablissement Anhydrous crystalline form of valacyclovir hydrochloride
AU2003232719A1 (en) * 2003-05-30 2005-01-21 Eos Eczacibasi Ozgun Kimyasal Urunler Sanayi Ve Ticaret A.S. Novel crystalline forms of valacyclovir hydrochloride
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DE102004054054A1 (de) 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
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US20070112193A1 (en) * 2005-11-14 2007-05-17 Khunt Mayur D Valacyclovir process
PE20080251A1 (es) * 2006-05-04 2008-04-25 Boehringer Ingelheim Int Usos de inhibidores de dpp iv
MX2008014024A (es) 2006-05-04 2008-11-14 Boehringer Ingelheim Int Formas poliformas.
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GB9501178D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Guanine derivative

Also Published As

Publication number Publication date
SK285329B6 (sk) 2006-11-03
EA199700124A1 (ru) 1997-12-30
JPH11503718A (ja) 1999-03-30
ES2248806T3 (es) 2006-03-16
MX9705462A (es) 1997-10-31
IL116831A0 (en) 1996-05-14
NO315558B1 (no) 2003-09-22
IL116831A (en) 1998-10-30
EP0804436B1 (en) 2005-08-24
AP662A (en) 1998-08-19
CA2210799A1 (en) 1996-07-25
RS49518B (sr) 2006-10-27
JP3176633B2 (ja) 2001-06-18
YU3396A (sh) 1998-12-23
FI973063A7 (fi) 1997-09-18
AU4453996A (en) 1996-08-07
RO118693B1 (ro) 2003-09-30
DE69635106D1 (de) 2005-09-29
KR100376074B1 (ko) 2003-06-02
AP9701058A0 (en) 1997-10-31
DE69635106T2 (de) 2006-06-08
NO973326D0 (no) 1997-07-18
GEP20001940B (en) 2000-02-05
EA000364B1 (ru) 1999-06-24
IN182468B (es) 1999-04-17
US6107302A (en) 2000-08-22
EE9700175A (et) 1998-02-16
EE03528B1 (et) 2001-10-15
AU702794B2 (en) 1999-03-04
NZ298851A (en) 1999-01-28
HUP9801836A3 (en) 1999-06-28
SI0804436T1 (sl) 2006-02-28
BR9606768A (pt) 1997-12-30
CA2210799C (en) 2008-06-10
OA10499A (en) 2002-04-10
SK96597A3 (en) 1998-02-04
UA46001C2 (uk) 2002-05-15
NO973326L (no) 1997-09-16
GB9501178D0 (en) 1995-03-08
IS4527A (is) 1997-07-15
ATE302777T1 (de) 2005-09-15
KR19980701525A (ko) 1998-05-15
HU222993B1 (hu) 2004-01-28
PL182175B1 (pl) 2001-11-30
DK0804436T3 (da) 2005-12-27
BG101833A (bg) 1998-04-30
UY25779A1 (es) 2000-08-21
BG63393B1 (bg) 2001-12-29
CN1049893C (zh) 2000-03-01
FI973063L (fi) 1997-09-18
ZA96449B (en) 1996-08-07
IS2268B (is) 2007-07-15
TR199700656T1 (xx) 1998-03-21
CN1179159A (zh) 1998-04-15
EP0804436A1 (en) 1997-11-05
HRP960024B1 (en) 2005-08-31
CY2531B1 (en) 2006-04-12
CZ229497A3 (en) 1997-12-17
CZ297065B6 (cs) 2006-08-16
PL321326A1 (en) 1997-12-08
FI973063A0 (fi) 1997-07-18
WO1996022291A1 (en) 1996-07-25
HRP960024A2 (en) 1997-10-31
HUP9801836A2 (hu) 1999-05-28

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