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AR000555A1 - Uso de composiciones anabolicas para la masa osea en base a cantidades efectivas no toxicas del ácido Ä3-(n,n-dimetilamino)-1-hidroxipropilidenoÜbisfosfonico o la sal monosodica u otra sal farmacéuticamente aceptable del mismo - Google Patents

Uso de composiciones anabolicas para la masa osea en base a cantidades efectivas no toxicas del ácido Ä3-(n,n-dimetilamino)-1-hidroxipropilidenoÜbisfosfonico o la sal monosodica u otra sal farmacéuticamente aceptable del mismo

Info

Publication number
AR000555A1
AR000555A1 AR33481795A AR33481795A AR000555A1 AR 000555 A1 AR000555 A1 AR 000555A1 AR 33481795 A AR33481795 A AR 33481795A AR 33481795 A AR33481795 A AR 33481795A AR 000555 A1 AR000555 A1 AR 000555A1
Authority
AR
Argentina
Prior art keywords
hydroxypropylidene
dimethylamino
bone mass
pharmaceutically acceptable
anabolic
Prior art date
Application number
AR33481795A
Other languages
English (en)
Inventor
S Papapoulos
J L Ferretti
R Labriola
N Mondelo
E Roldan
Original Assignee
Gador Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gador Sa filed Critical Gador Sa
Publication of AR000555A1 publication Critical patent/AR000555A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Uso de una cantidad efectiva y no-tóxica del ácido [3-(N,N-dimetilamino)-1-hidroxipropilideno]-bis-fosfónico o de la sal monosódica u otra salfarmacéuticamente aceptable para la preparación de un medicamento para la preservación y aumentoanabó lico de la masa ósea y para el mejoramiento de laspropiedades biomecánicas del hueso en humanos u otros animales afectados de pérdida de masa ósea.
AR33481795A 1994-12-28 1995-12-27 Uso de composiciones anabolicas para la masa osea en base a cantidades efectivas no toxicas del ácido Ä3-(n,n-dimetilamino)-1-hidroxipropilidenoÜbisfosfonico o la sal monosodica u otra sal farmacéuticamente aceptable del mismo AR000555A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP94120799 1994-12-28

Publications (1)

Publication Number Publication Date
AR000555A1 true AR000555A1 (es) 1997-07-10

Family

ID=8216571

Family Applications (1)

Application Number Title Priority Date Filing Date
AR33481795A AR000555A1 (es) 1994-12-28 1995-12-27 Uso de composiciones anabolicas para la masa osea en base a cantidades efectivas no toxicas del ácido Ä3-(n,n-dimetilamino)-1-hidroxipropilidenoÜbisfosfonico o la sal monosodica u otra sal farmacéuticamente aceptable del mismo

Country Status (11)

Country Link
EP (1) EP0800397B1 (es)
JP (1) JP3796693B2 (es)
KR (1) KR100385697B1 (es)
AR (1) AR000555A1 (es)
AU (1) AU701258B2 (es)
BR (1) BR9510123A (es)
CA (1) CA2208714C (es)
DE (1) DE69534923T2 (es)
ES (1) ES2262145T3 (es)
WO (1) WO1996019998A1 (es)
ZA (1) ZA9510995B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0753523A1 (en) * 1995-07-10 1997-01-15 Gador S.A. Amino-substituted bisphosphonic acids
DE19719680A1 (de) 1997-05-09 1998-11-19 Boehringer Mannheim Gmbh Verwendung von Diphosphonsäuren zur präventiven Behandlung von Spätfolgen bei Harnblasenerweiterung oder Harnblasenersatz
ES2231919T3 (es) * 1997-07-15 2005-05-16 Gador S.A. Forma cristalina de sal monosodica monohidrato del acido n,n-dimetil-3-amino-1-hidroxipropano-1,1-difosfonico.
AR013994A1 (es) * 1998-10-30 2001-01-31 Gador Sa Procedimiento y preparaciones que modulan selectivamente la funcion del osteoblasto para la prevencion y tratamiento de las osteopatias fragilizantes.
US6416737B1 (en) * 1998-11-19 2002-07-09 Board Of Trustees Of The University Of Arkansas Increasing bone strength with selected bisphosphonates
WO2002058708A1 (en) 2001-01-23 2002-08-01 Gador S.A. Composition comprising bisphosphonates for prevention and/or treatment of metabolic diseases of bones, process for preparing such composition and use thereof
RU2387451C2 (ru) 2002-05-10 2010-04-27 Ф.Хоффманн-Ля Рош Аг Бисфосфоновые кислоты, предназначенные для лечения и профилактики остеопороза
WO2008157050A1 (en) * 2007-06-19 2008-12-24 Albemarle Corporation Processes for manufacturing bisphosphonic acids

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0381296B1 (en) * 1984-04-30 1994-11-30 THE PROCTER & GAMBLE COMPANY Kit for use in the treatment of osteoporosis
RU2113848C1 (ru) * 1991-02-26 1998-06-27 Норвич Итон Фармасьютикалз, Инк. Способ лечения остеопороза, композиция для лечения остеопороза, применение активно действующего на кости фосфоната и эстрогенного гормона для лечения остеопороза
NZ246456A (en) * 1991-12-17 1997-03-24 Procter & Gamble Pharma Use of bone active phosphonate and a parathyroid hormone to prepare medicaments for a thirty day treatment regimen for osteoporosis
ATE161423T1 (de) * 1992-06-30 1998-01-15 Procter & Gamble Pharma Verwendung von phosphinate zur behandlung der osteoporose
EP0600834A1 (en) * 1992-11-30 1994-06-08 Ciba-Geigy Ag Use of methanebisphosphonic acid derivatives for the manufacture of a medicament for fracture healing
US5366965A (en) * 1993-01-29 1994-11-22 Boehringer Mannheim Gmbh Regimen for treatment or prophylaxis of osteoporosis

Also Published As

Publication number Publication date
KR100385697B1 (ko) 2003-08-21
ES2262145T3 (es) 2006-11-16
AU701258B2 (en) 1999-01-21
DE69534923D1 (de) 2006-05-18
JP3796693B2 (ja) 2006-07-12
EP0800397A1 (en) 1997-10-15
BR9510123A (pt) 1997-12-30
WO1996019998A1 (en) 1996-07-04
CA2208714A1 (en) 1996-07-04
EP0800397B1 (en) 2006-04-05
AU4434796A (en) 1996-07-19
ZA9510995B (en) 1997-06-30
DE69534923T2 (de) 2006-11-23
CA2208714C (en) 2003-10-21
JPH11502506A (ja) 1999-03-02

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