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AR004669A1 - Nuevos derivados de la n[(1,4-diazabiciclo[2.2.2]oct-2-il)metil]benzamida, procedimiento para prepararlos y los medicamentos y las composicionesfarmaceuticas que los contienen. - Google Patents

Nuevos derivados de la n[(1,4-diazabiciclo[2.2.2]oct-2-il)metil]benzamida, procedimiento para prepararlos y los medicamentos y las composicionesfarmaceuticas que los contienen.

Info

Publication number
AR004669A1
AR004669A1 ARP960103118A AR10311896A AR004669A1 AR 004669 A1 AR004669 A1 AR 004669A1 AR P960103118 A ARP960103118 A AR P960103118A AR 10311896 A AR10311896 A AR 10311896A AR 004669 A1 AR004669 A1 AR 004669A1
Authority
AR
Argentina
Prior art keywords
benzamide
oct
drugs
preparing
pharmaceutical compositions
Prior art date
Application number
ARP960103118A
Other languages
English (en)
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of AR004669A1 publication Critical patent/AR004669A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D245/00—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms
    • C07D245/02—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Se describen nuevos derivados de la N-[(1,4-diazabiciclo[2.2.2]oct-2-il] benzamida de la fórmula general (I), en donde R1 es un grupo metoxi ociclopropimetoxi, R2 es un átomo de hidrógeno, de cloro o de bromo, o bien también R1 y R2 forman juntos, un grupo de la fórmula -O-CH2-O-,-O-(CH2)2-,-O-(CH2)2-O-ú -O-(CH2)3-O-, R3 es un átomo de hidrógeno o un grupo amino, y R4 es un átomo de hidrógeno, de cloro o de bromo. También se describen elprocedimiento para preparar dichos derivados y losmedicamentos y composiciones farmacéuticas que las contienen.
ARP960103118A 1995-06-13 1996-06-12 Nuevos derivados de la n[(1,4-diazabiciclo[2.2.2]oct-2-il)metil]benzamida, procedimiento para prepararlos y los medicamentos y las composicionesfarmaceuticas que los contienen. AR004669A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9506951A FR2735475B1 (fr) 1995-06-13 1995-06-13 Derives de n-((1,4-diazabicyclo(2.2.2)oct-2-yl)methyl) benzamide, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
AR004669A1 true AR004669A1 (es) 1999-03-10

Family

ID=9479885

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP960103118A AR004669A1 (es) 1995-06-13 1996-06-12 Nuevos derivados de la n[(1,4-diazabiciclo[2.2.2]oct-2-il)metil]benzamida, procedimiento para prepararlos y los medicamentos y las composicionesfarmaceuticas que los contienen.

Country Status (19)

Country Link
US (1) US5663173A (es)
EP (1) EP0748807A1 (es)
JP (1) JPH09118680A (es)
KR (1) KR970001335A (es)
CN (1) CN1143644A (es)
AR (1) AR004669A1 (es)
AU (1) AU704388B2 (es)
CA (1) CA2178849A1 (es)
CO (1) CO4700470A1 (es)
CZ (1) CZ171696A3 (es)
FR (1) FR2735475B1 (es)
HU (1) HUP9601620A3 (es)
IL (1) IL118644A (es)
NO (1) NO305251B1 (es)
NZ (1) NZ286805A (es)
PL (1) PL314745A1 (es)
SK (1) SK75296A3 (es)
TW (1) TW372238B (es)
ZA (1) ZA964985B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2756563B1 (fr) * 1996-12-04 1998-12-24 Synthelabo Derives de benzoate de 1,4-diazabicyclo[2.2.2]oct-2-yl- methyle, leur preparation et leur application en therapeutique
FR2756564B1 (fr) * 1996-12-04 2004-05-14 Synthelabo Derives d'acide quinoleine-8-carboxylique, leur preparation et leur application en therapeutique
KR100619639B1 (ko) 1997-11-07 2006-09-06 파마시아 앤드 업존 캄파니 엘엘씨 옥사졸리디논의 제조 방법
TR200103760T2 (tr) * 1998-06-15 2002-06-21 Sepracor Inc. Apne, bulimi ve başka bozuklukların tedavi edilmesi için optik açıdan saf (-) norsisapridin kullanımı
EP1464333A3 (en) * 1998-06-15 2004-12-15 Sepracor Inc. Use of optically pure (-) norcisapride in the treatment of apnea, bulimia, and other disorders
JP2002518352A (ja) * 1998-06-15 2002-06-25 セプラコア インコーポレーテッド 無呼吸、過食症およびその他の障害を治療するための光学的に純粋な（＋）−ノルシスアプリドの使用
EP1468685A3 (en) * 1998-06-15 2004-12-15 Sepracor Inc. Use of optically pure (+)-norcisapride for treating apnea, bulimia and other disorders
US6353005B1 (en) 1999-03-02 2002-03-05 Sepracor, Inc. Method and compositions using (+) norcisapride in combination with proton pump inhibitors or H2 receptor antagonist
US6362202B1 (en) 1999-03-02 2002-03-26 Sepracor Inc. Methods and compositions using (−) norcisapride in combination with proton pump inhibitors or H2 receptor antagonists
US20090312344A1 (en) * 2004-05-31 2009-12-17 Mohammad Salman Arylpiperazine derivatives as adrenergic receptor antagonists
US8071605B2 (en) 2008-12-12 2011-12-06 Astrazeneca Ab Piperidine compounds for use in the treatment of bacterial infections
JP5549847B2 (ja) * 2009-11-16 2014-07-16 東ソー株式会社 Ｎ−（２−アルコキシメチル）トリエチレンジアミン類の製造法
GB201219820D0 (en) * 2012-11-05 2012-12-19 Isis Innovation Compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4888353A (en) * 1986-02-28 1989-12-19 Erbamont, Inc. Carboxamides useful as antiemetic or antipsychotic agents
SG49153A1 (en) * 1991-09-12 1998-05-18 Smithkline Beecham Plc 5-HT4 receptor antagonists
TW282460B (es) * 1993-12-28 1996-08-01 Yamanouchi Pharma Co Ltd

Also Published As

Publication number Publication date
NO305251B1 (no) 1999-04-26
FR2735475B1 (fr) 1997-07-11
NO962477D0 (no) 1996-06-12
KR970001335A (ko) 1997-01-24
EP0748807A1 (fr) 1996-12-18
HUP9601620A3 (en) 1998-07-28
ZA964985B (en) 1997-01-23
AU704388B2 (en) 1999-04-22
JPH09118680A (ja) 1997-05-06
HUP9601620A2 (en) 1997-01-28
IL118644A (en) 2000-02-17
NZ286805A (en) 1998-03-25
HU9601620D0 (en) 1996-08-28
CN1143644A (zh) 1997-02-26
CA2178849A1 (en) 1996-12-14
US5663173A (en) 1997-09-02
NO962477L (no) 1996-12-16
IL118644A0 (en) 1996-10-16
AU5591296A (en) 1997-01-02
SK75296A3 (en) 1997-05-07
MX9602306A (es) 1997-10-31
CZ171696A3 (en) 1997-01-15
TW372238B (en) 1999-10-21
CO4700470A1 (es) 1998-12-29
PL314745A1 (en) 1996-12-23
FR2735475A1 (fr) 1996-12-20

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