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AR004364A1 - Compuesto derivado de pirazol, procedimiento para su preparacion y composicion farmaceutica que lo contiene. - Google Patents

Compuesto derivado de pirazol, procedimiento para su preparacion y composicion farmaceutica que lo contiene.

Info

Publication number
AR004364A1
AR004364A1 ARP960105525A ARP960105525A AR004364A1 AR 004364 A1 AR004364 A1 AR 004364A1 AR P960105525 A ARP960105525 A AR P960105525A AR P960105525 A ARP960105525 A AR P960105525A AR 004364 A1 AR004364 A1 AR 004364A1
Authority
AR
Argentina
Prior art keywords
alkyl
hydrogen
substituents
alkoxy
group
Prior art date
Application number
ARP960105525A
Other languages
English (en)
Original Assignee
Dupuis Laurent
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dupuis Laurent filed Critical Dupuis Laurent
Publication of AR004364A1 publication Critical patent/AR004364A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Compuesto de fórmula (I), en donde: X1 representa un grupo -NR1R2, o un grupo -OR2; G2, G3, G4, G5, G6 y W2, W3, W4, W5, W6 son idénticos o diferentes,y representan cada uno independientemente hidrógeno, un átomo de halógeno, un (C1-C4)-alquilo, un (C1-C4)-alcoxi, un trifluormetilo, un nitro, un (C1-C4)-alquiltio; con la condición de que por lo menos uno de los substituyentes G2, G3, G4, G5, G6 y por lo menos uno de los substituyentes W2, W3, W4, W5, W6 seandiferentes de hidrógeno; R1re presenta hidrógeno o un (C1-C4)-alquilo; R2 representa un radical carbocíclico no aromático en (C3-C15) no substituido osubstituido una o varias veces por un substituyente elegido entre: un átomo de halógeno, un (C1-C4)-alquilo, un (C1-C4)- alcoxi; R3 representa hidrógeno o ungrupo -CH2-R6; R4 y R5 representan cada uno independientemente un hidrógeno, un (C1-C4)-alquilo o un trifluorometilo; o bien R4 representa hidrógeno y R5 y W4juntos constituyen un radical etileno o un radicaltrimetil eno; R6 representa hidrógeno, o cuando los substituyentes G2, G3, G4, G5 y/o G6 son distintos deun (C1-C4)-alquilo, R6 representa hidrógeno, un (C1-C4)-alquilo, un fluor, un hidroxi, un (C1-C5)-alcoxi, un (C1-C5)-alquiltio, unhidroxi(C1-C5)-alco xi, unciano, un (C1-C5)-alquil-sulfinilo, un (C1-C5)-alquilsulfonilo; así como sus sales.
ARP960105525A 1995-12-08 1996-12-06 Compuesto derivado de pirazol, procedimiento para su preparacion y composicion farmaceutica que lo contiene. AR004364A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9514547A FR2742148B1 (fr) 1995-12-08 1995-12-08 Nouveaux derives du pyrazole-3-carboxamide, procede pour leur preparation et compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
AR004364A1 true AR004364A1 (es) 1998-11-04

Family

ID=9485291

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP960105525A AR004364A1 (es) 1995-12-08 1996-12-06 Compuesto derivado de pirazol, procedimiento para su preparacion y composicion farmaceutica que lo contiene.

Country Status (34)

Country Link
US (1) US5925768A (es)
EP (2) EP0868420B1 (es)
JP (1) JP3510270B2 (es)
KR (1) KR100488610B1 (es)
CN (1) CN1101813C (es)
AR (1) AR004364A1 (es)
AT (1) ATE191211T1 (es)
AU (1) AU718763B2 (es)
BR (1) BR9611986A (es)
CA (1) CA2239489C (es)
CZ (1) CZ294307B6 (es)
DE (1) DE69607484T2 (es)
DK (1) DK0868420T3 (es)
EE (1) EE04674B1 (es)
ES (1) ES2148820T3 (es)
FR (1) FR2742148B1 (es)
GR (1) GR3033626T3 (es)
HU (1) HUP9901244A3 (es)
IL (1) IL124801A (es)
IS (1) IS4765A (es)
MX (1) MX9804565A (es)
MY (1) MY115228A (es)
NO (1) NO310683B1 (es)
NZ (1) NZ323962A (es)
PL (1) PL186466B1 (es)
PT (1) PT868420E (es)
RU (1) RU2170230C2 (es)
SI (1) SI0868420T1 (es)
SK (1) SK283706B6 (es)
TR (1) TR199801041T2 (es)
TW (1) TW402594B (es)
UA (1) UA44913C2 (es)
WO (1) WO1997021682A1 (es)
ZA (1) ZA9610299B (es)

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Also Published As

Publication number Publication date
CN1207731A (zh) 1999-02-10
WO1997021682A1 (fr) 1997-06-19
HUP9901244A2 (hu) 1999-08-30
PL186466B1 (pl) 2004-01-30
EP0868420B1 (fr) 2000-03-29
RU2170230C2 (ru) 2001-07-10
JP3510270B2 (ja) 2004-03-22
EE04674B1 (et) 2006-08-15
US5925768A (en) 1999-07-20
ES2148820T3 (es) 2000-10-16
EP0885889A3 (fr) 1999-01-27
MY115228A (en) 2003-04-30
SI0868420T1 (en) 2000-10-31
NZ323962A (en) 1999-05-28
FR2742148B1 (fr) 1999-10-22
PL327177A1 (en) 1998-11-23
TR199801041T2 (xx) 1998-08-21
CZ177598A3 (cs) 1998-10-14
ZA9610299B (en) 1997-06-18
MX9804565A (es) 1998-09-30
IL124801A0 (en) 1999-01-26
CA2239489C (en) 2006-05-09
NO982589D0 (no) 1998-06-05
PT868420E (pt) 2000-08-31
CA2239489A1 (en) 1997-06-19
AU1101097A (en) 1997-07-03
EP0885889A2 (fr) 1998-12-23
SK283706B6 (sk) 2003-12-02
HUP9901244A3 (en) 2000-12-28
JP2000502080A (ja) 2000-02-22
EP0868420A1 (fr) 1998-10-07
IL124801A (en) 2004-07-25
AU718763B2 (en) 2000-04-20
BR9611986A (pt) 1999-02-17
CZ294307B6 (cs) 2004-11-10
UA44913C2 (uk) 2002-03-15
DE69607484D1 (de) 2000-05-04
DE69607484T2 (de) 2000-10-26
GR3033626T3 (en) 2000-10-31
DK0868420T3 (da) 2000-08-21
KR100488610B1 (ko) 2005-09-26
NO982589L (no) 1998-08-03
EE9800171A (et) 1998-12-15
TW402594B (en) 2000-08-21
ATE191211T1 (de) 2000-04-15
NO310683B1 (no) 2001-08-13
SK75898A3 (en) 1999-01-11
CN1101813C (zh) 2003-02-19
KR19990072004A (ko) 1999-09-27
IS4765A (is) 1998-06-08
FR2742148A1 (fr) 1997-06-13

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