[go: up one dir, main page]

NO993901D0 - Bicyclic amino acids - Google Patents

Bicyclic amino acids

Info

Publication number
NO993901D0
NO993901D0 NO993901A NO993901A NO993901D0 NO 993901 D0 NO993901 D0 NO 993901D0 NO 993901 A NO993901 A NO 993901A NO 993901 A NO993901 A NO 993901A NO 993901 D0 NO993901 D0 NO 993901D0
Authority
NO
Norway
Prior art keywords
amino acids
bicyclic amino
bicyclic
acids
amino
Prior art date
Application number
NO993901A
Other languages
Norwegian (no)
Other versions
NO313289B1 (en
NO993901L (en
Inventor
Beate Diefenbach
Simon Goodman
Joachim Morz
Peter Raddatz
Friedrich Rippmann
Matthias Wiesner
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of NO993901D0 publication Critical patent/NO993901D0/en
Publication of NO993901L publication Critical patent/NO993901L/en
Publication of NO313289B1 publication Critical patent/NO313289B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/281,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/341,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/361,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/101,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/141,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/161,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/201,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO19993901A 1997-02-13 1999-08-12 Bisyclic amino acids, process for their preparation, pharmaceutical composition, process for their preparation, use of the compounds for the preparation of a drug use as <alfa> v-integrin inhibitor NO313289B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19705450A DE19705450A1 (en) 1997-02-13 1997-02-13 Bicyclic aromatic amino acids
PCT/EP1998/000636 WO1998035949A1 (en) 1997-02-13 1998-02-06 Bicyclic amino acids

Publications (3)

Publication Number Publication Date
NO993901D0 true NO993901D0 (en) 1999-08-12
NO993901L NO993901L (en) 1999-10-12
NO313289B1 NO313289B1 (en) 2002-09-09

Family

ID=7820093

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19993901A NO313289B1 (en) 1997-02-13 1999-08-12 Bisyclic amino acids, process for their preparation, pharmaceutical composition, process for their preparation, use of the compounds for the preparation of a drug use as <alfa> v-integrin inhibitor

Country Status (25)

Country Link
EP (1) EP0964856B1 (en)
JP (1) JP4327257B2 (en)
KR (1) KR20000071030A (en)
CN (1) CN1085205C (en)
AR (1) AR010894A1 (en)
AT (1) ATE225776T1 (en)
AU (1) AU735313B2 (en)
BR (1) BR9807345A (en)
CA (1) CA2280727C (en)
CY (1) CY2341B1 (en)
CZ (1) CZ297366B6 (en)
DE (2) DE19705450A1 (en)
DK (1) DK0964856T3 (en)
ES (1) ES2183332T3 (en)
HU (1) HUP0001138A3 (en)
ID (1) ID22533A (en)
NO (1) NO313289B1 (en)
PL (1) PL335101A1 (en)
PT (1) PT964856E (en)
RU (1) RU2187506C2 (en)
SI (1) SI0964856T1 (en)
SK (1) SK284646B6 (en)
TR (1) TR199901962T2 (en)
WO (1) WO1998035949A1 (en)
ZA (1) ZA981178B (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040063790A1 (en) * 1996-05-31 2004-04-01 The Scripps Research Institute Methods for inhibition of angiogenesis
ATE542797T1 (en) 1998-04-09 2012-02-15 Meiji Seika Pharma Co Ltd AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS
PL351279A1 (en) 1999-04-13 2003-04-07 Abbott Gmbh & Co Kg Integrin receptor ligands
AU6316900A (en) 1999-08-05 2001-03-05 Meiji Seika Kaisha Ltd. Omega-amino-alpha-hydroxycarboxylic acid derivatives having integrin alphavbeta3antagonism
EP1244616A1 (en) * 1999-12-24 2002-10-02 SmithKline Beecham plc (hetero)bicyclylmethanesulfonylamino-substituted hydroxamic acid derivatives
DE60101351T2 (en) * 2000-01-25 2004-10-07 Kaneka Corp METHOD FOR PRODUCING OPTICALLY ACTIVE, N-SUBSTITUTED AZETIDINE-2-CARBONIC ACIDS
CN100571772C (en) * 2000-11-01 2009-12-23 默克专利有限公司 Use of antagonists of the integrin receptors α v β 3 and/or α v β 5 for the production of medicaments for the treatment of eye diseases
ATE415163T1 (en) * 2000-11-01 2008-12-15 Merck Patent Gmbh METHODS AND COMPOSITIONS FOR TREATING EYE DISEASES
EP1404860B8 (en) 2001-05-30 2013-12-25 The Scripps Research Institute Delivery system for nucleic acids
HUP0401605A3 (en) 2001-08-01 2012-09-28 Merck Patent Gmbh Integrin inhibitors for the treatment of eye diseases
RU2004127577A (en) * 2002-02-14 2005-05-27 Мерк Патент ГмбХ (DE) METHODS AND COMPOSITIONS FOR TREATING EYE DISEASES
FR2847254B1 (en) * 2002-11-19 2005-01-28 Aventis Pharma Sa NOVEL VITRONECTIN RECEPTOR ANTAGONIST DERIVATIVES, PROCESS FOR PREPARING THEM, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS REFLECTING THEM
DE10305784A1 (en) * 2003-02-12 2004-08-26 Merck Patent Gmbh 3-Oxo-3,4-dihydro-2H-benz-(1,4)-oxazin-6-yl)-propionic acid derivative preparation, for use as integrin inhibitors with e.g. antitumor action, by multi-stage process giving diastereomerically pure product
DE10337863A1 (en) 2003-08-18 2005-03-17 Merck Patent Gmbh Use of chromene-4-one derivatives
EP2484364B1 (en) * 2004-06-04 2014-02-19 The Scripps Research Institute Compositions for treatment of neovascular diseases
UA87854C2 (en) 2004-06-07 2009-08-25 Мерк Энд Ко., Инк. N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators
PL2380881T3 (en) * 2008-12-26 2017-07-31 Sumitomo Dainippon Pharma Co., Ltd. Novel bicyclic heterocyclic compound
WO2011024987A1 (en) * 2009-08-31 2011-03-03 塩野義製薬株式会社 Aromatic fused heterocyclic derivative and pharmaceutical composition containing same
AR090259A1 (en) 2012-03-06 2014-10-29 Boehringer Ingelheim Int BENZODIOXAN INHIBITORS OF LEUCOTRENE PRODUCTION FOR COMBINATION THERAPY
TW201416354A (en) 2012-07-17 2014-05-01 Boehringer Ingelheim Int Inhibitors of leukotriene production
EP3022194B1 (en) 2013-07-15 2017-05-17 Boehringer Ingelheim International GmbH Inhibitors of leukotriene production
WO2015009609A1 (en) 2013-07-15 2015-01-22 Boehringer Ingelheim International Gmbh Inhibitors of leukotriene production
MX2016015467A (en) 2014-05-30 2017-03-23 Pfizer Carbonitrile derivatives as selective androgen receptor modulators.
WO2023275715A1 (en) 2021-06-30 2023-01-05 Pfizer Inc. Metabolites of selective androgen receptor modulators
CA3221177A1 (en) 2021-11-01 2023-05-04 Meghan Kerrisk Campbell Benzodioxane modulators of leukotriene a4 hydrolase (lta4h) for prevention and treatment of aging-associated diseases

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3151690A1 (en) * 1981-12-29 1983-07-07 Hoechst Ag, 6230 Frankfurt Novel derivatives of bicyclic amino acids, process for their preparation, compositions containing them and their use, and also novel bicyclic amino acids as intermediates and process for their preparation
FR2674854B1 (en) * 1991-04-04 1995-03-03 Bouchara NEW QUINOLONES THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS THEREOF.
US5648368A (en) * 1992-12-01 1997-07-15 Merck & Co., Inc. Fibrinogen receptor antagonists
DE69528829T2 (en) * 1994-05-27 2003-08-07 Merck & Co., Inc. PREPARATIONS FOR INHIBITING BONE RESORPTION BROUGHT BY OSTEOCLASTIC
DE19548709A1 (en) * 1995-12-23 1997-07-03 Merck Patent Gmbh Tyrosine derivatives
DE19654483A1 (en) * 1996-06-28 1998-01-02 Merck Patent Gmbh Phenylalanine derivatives
EP0907637A1 (en) * 1996-06-28 1999-04-14 MERCK PATENT GmbH Phenylalamine derivatives as integrin inhibitors

Also Published As

Publication number Publication date
CN1085205C (en) 2002-05-22
SI0964856T1 (en) 2003-04-30
HUP0001138A3 (en) 2002-10-28
DE19705450A1 (en) 1998-08-20
ID22533A (en) 1999-10-28
AU735313B2 (en) 2001-07-05
WO1998035949A1 (en) 1998-08-20
RU2187506C2 (en) 2002-08-20
SK284646B6 (en) 2005-08-04
EP0964856B1 (en) 2002-10-09
PL335101A1 (en) 2000-04-10
NO313289B1 (en) 2002-09-09
NO993901L (en) 1999-10-12
HUP0001138A2 (en) 2001-05-28
JP2001511789A (en) 2001-08-14
DK0964856T3 (en) 2003-02-10
ES2183332T3 (en) 2003-03-16
ATE225776T1 (en) 2002-10-15
PT964856E (en) 2003-02-28
CY2341B1 (en) 2004-02-06
CA2280727C (en) 2008-05-06
AU6620698A (en) 1998-09-08
DE59805895D1 (en) 2002-11-14
AR010894A1 (en) 2000-07-12
JP4327257B2 (en) 2009-09-09
SK107199A3 (en) 2000-05-16
CN1252064A (en) 2000-05-03
BR9807345A (en) 2000-03-21
CZ297366B6 (en) 2006-11-15
EP0964856A1 (en) 1999-12-22
CA2280727A1 (en) 1998-08-20
TR199901962T2 (en) 1999-12-21
KR20000071030A (en) 2000-11-25
ZA981178B (en) 1999-05-21
CZ287599A3 (en) 1999-11-17

Similar Documents

Publication Publication Date Title
NO993901L (en) Bicyclic amino acids
DK0877018T3 (en) Sulfonylaminocarboxylic acids
NO20002990L (en) New surface protein
DE69839603D1 (en) ORNAMENTAL PROTEINS
FI953837A0 (en) Synthetic activating amino acids
IS5375A (en) KAY-Innovative Immune Protein
NO2010013I2 (en) Recombinant FSH-CTP
DE69832623D1 (en) MICRO-MADE CIRCLES
NO985680D0 (en) peptide
DE69815952D1 (en) polisher
DE69830139D1 (en) ULTRASONIC LOCKENWICKELGERÄT
NO994548D0 (en) Railing
NO983849D0 (en) peptide
DE69816146D1 (en) polisher
BR9609671A (en) Amino uracilas substituted
DE69838161D1 (en) polisher
TR199701666A3 (en) Proteins
DK0862850T3 (en) combine
DE69808762D1 (en) CONNECTION PART
DE69834398D1 (en) PENDANT
DE59806788D1 (en) Lights Set
DK1017798T3 (en) lunasin peptides
NO20000976D0 (en) peptides
ATA188297A (en) FITTING
ATE204219T1 (en) BOND HEAD

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees