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NO992705L - 3-pyridylenantiomere og deres anvendelse som analgetika - Google Patents

3-pyridylenantiomere og deres anvendelse som analgetika

Info

Publication number
NO992705L
NO992705L NO992705A NO992705A NO992705L NO 992705 L NO992705 L NO 992705L NO 992705 A NO992705 A NO 992705A NO 992705 A NO992705 A NO 992705A NO 992705 L NO992705 L NO 992705L
Authority
NO
Norway
Prior art keywords
analgesics
pyridylene
enantiomers
formula
compounds
Prior art date
Application number
NO992705A
Other languages
English (en)
Other versions
NO992705D0 (no
Inventor
Mark W Holladay
Stephen P Arneric
Hao Bai
Michael J Dart
Nan-Horng Lin
John K Lynch
Yat Sun Or
Keith B Ryther
James P Sullivan
James T Wasicak
Paul P Ehrlich
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of NO992705D0 publication Critical patent/NO992705D0/no
Publication of NO992705L publication Critical patent/NO992705L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
NO992705A 1996-12-10 1999-06-03 3-pyridylenantiomere og deres anvendelse som analgetika NO992705L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3232196P 1996-12-10 1996-12-10
US76327896A 1996-12-10 1996-12-10
PCT/US1997/022811 WO1998025920A1 (en) 1996-12-10 1997-12-10 3-pyridyl enantiomers and their use as analgesics

Publications (2)

Publication Number Publication Date
NO992705D0 NO992705D0 (no) 1999-06-03
NO992705L true NO992705L (no) 1999-08-03

Family

ID=26708255

Family Applications (1)

Application Number Title Priority Date Filing Date
NO992705A NO992705L (no) 1996-12-10 1999-06-03 3-pyridylenantiomere og deres anvendelse som analgetika

Country Status (21)

Country Link
EP (1) EP0950057B1 (no)
JP (2) JP4272261B2 (no)
KR (2) KR100422995B1 (no)
CN (1) CN1125064C (no)
AT (1) ATE227717T1 (no)
AU (1) AU733881B2 (no)
BG (1) BG64196B1 (no)
BR (1) BR9714677A (no)
CA (2) CA2273917C (no)
DE (1) DE69717148T2 (no)
DK (1) DK0950057T3 (no)
ES (1) ES2189003T3 (no)
HU (1) HUP0001110A3 (no)
IL (1) IL130083A0 (no)
NO (1) NO992705L (no)
NZ (1) NZ335810A (no)
PL (1) PL333920A1 (no)
PT (1) PT950057E (no)
SK (1) SK75999A3 (no)
TR (1) TR199901904T2 (no)
WO (1) WO1998025920A1 (no)

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MXPA00009619A (es) 1998-04-02 2006-03-09 Targacept Inc Composiciones farmaceuticas y metodos de uso.
US6054451A (en) * 1998-04-21 2000-04-25 Algos Pharmaceutical Corporation Analgesic composition and method for alleviating pain
US6541669B1 (en) * 1998-06-08 2003-04-01 Theravance, Inc. β2-adrenergic receptor agonists
US20010031771A1 (en) 1999-05-24 2001-10-18 Gary Maurice Dull Pharmaceutical compositions and methods for use
US6103911A (en) * 1999-06-15 2000-08-15 Abbott Laboratories Process for reduction of (2R)-4-oxoazetidinone-2-carboxylic acid
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US6818787B2 (en) 2001-06-11 2004-11-16 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7232924B2 (en) 2001-06-11 2007-06-19 Xenoport, Inc. Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
JP2006504634A (ja) * 2002-05-15 2006-02-09 アボット・ラボラトリーズ 神経障害性疼痛の治療
EP1741709A1 (en) 2005-06-28 2007-01-10 Sanofi-Aventis Deutschland GmbH Heteroaryl-substituted amides comprising a saturated linker group, and their use as pharmaceuticals
AU2006324089A1 (en) 2005-12-09 2007-06-14 F. Hoffmann-La Roche Ag Tricyclic amide derivatives useful for treating obesity
TW200800020A (en) * 2006-01-26 2008-01-01 Basf Ag Methods to use 3-pyridyl derivatives as pesticides
WO2008028903A2 (en) 2006-09-04 2008-03-13 Neurosearch A/S Pharmaceutical combinations of a nicotine receptor modulator and a cognitive enhancer
DE102007058504A1 (de) 2007-12-05 2009-07-09 Acino Ag Transdermales therapeutisches System mit einem Gehalt an einem Modulator für nikotinische Acetylcholinrezeptoren (nAChR)
CA2738806A1 (en) 2008-10-14 2010-04-22 Psychogenics, Inc. Nicotinic acetylcholine receptor ligands and the uses thereof
AR075988A1 (es) 2009-04-09 2011-05-11 Lilly Co Eli Compuesto de piridiloxi - pirrolidina inhibidor de recaptacion de serotonina y norepinefrina, composicion farmaceutica que lo comprende y su uso para la manufactura de un medicamento util para el tratamiento de dolor cronico
US8474529B2 (en) * 2009-04-09 2013-07-02 Regency Technologies Llc Control of concentric tubing direction
KR20140027939A (ko) 2011-06-30 2014-03-07 도레이 카부시키가이샤 지양제
US9890137B2 (en) 2013-03-27 2018-02-13 Georgetown University 2-halo-5-alkynyl-pyridyl nicotinic ligands
CN110944689B (zh) 2017-06-07 2022-12-09 施菲姆德控股有限责任公司 血管内流体运动设备、系统和使用方法
US11511103B2 (en) 2017-11-13 2022-11-29 Shifamed Holdings, Llc Intravascular fluid movement devices, systems, and methods of use
EP4085965A1 (en) 2018-02-01 2022-11-09 Shifamed Holdings, LLC Intravascular blood pumps and methods of use and manufacture
WO2020028537A1 (en) 2018-07-31 2020-02-06 Shifamed Holdings, Llc Intravascaular blood pumps and methods of use
JP7470108B2 (ja) 2018-10-05 2024-04-17 シファメド・ホールディングス・エルエルシー 血管内血液ポンプおよび使用の方法
WO2021011473A1 (en) 2019-07-12 2021-01-21 Shifamed Holdings, Llc Intravascular blood pumps and methods of manufacture and use
WO2021016372A1 (en) 2019-07-22 2021-01-28 Shifamed Holdings, Llc Intravascular blood pumps with struts and methods of use and manufacture
US12465748B2 (en) 2019-08-07 2025-11-11 Supira Medical, Inc. Catheter blood pumps and collapsible pump housings
EP4034192B1 (en) 2019-09-25 2025-12-24 Supira Medical, Inc. Intravascular blood pump systems and methods of use and control thereof
US12102815B2 (en) 2019-09-25 2024-10-01 Shifamed Holdings, Llc Catheter blood pumps and collapsible pump housings
WO2021062260A1 (en) 2019-09-25 2021-04-01 Shifamed Holdings, Llc Catheter blood pumps and collapsible blood conduits
US12409310B2 (en) 2019-12-11 2025-09-09 Shifamed Holdings, Llc Descending aorta and vena cava blood pumps

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8301702D0 (en) * 1983-01-21 1983-02-23 Shell Int Research Azetidine compounds
US4902684A (en) * 1988-06-20 1990-02-20 E. R. Squibb & Sons, Inc. Benzazepine and benzothiazepine derivatives
US5068234A (en) * 1990-02-26 1991-11-26 Sterling Drug Inc. 3-arylcarbonyl-1-(c-attached-n-heteryl)-1h-indoles
IL107184A (en) * 1992-10-09 1997-08-14 Abbott Lab Heterocyclic ether compounds that enhance cognitive function
US5585388A (en) * 1995-04-07 1996-12-17 Sibia Neurosciences, Inc. Substituted pyridines useful as modulators of acetylcholine receptors
IL118279A (en) * 1995-06-07 2006-10-05 Abbott Lab Compounds 3 - Pyridyloxy (or Thio) Alkyl Heterocyclic Pharmaceutical Compositions Containing Them and Their Uses for Preparing Drugs to Control Synaptic Chemical Transmission
US5629325A (en) * 1996-06-06 1997-05-13 Abbott Laboratories 3-pyridyloxymethyl heterocyclic ether compounds useful in controlling chemical synaptic transmission

Also Published As

Publication number Publication date
JP2001504857A (ja) 2001-04-10
DK0950057T3 (da) 2003-03-10
KR20000069399A (ko) 2000-11-25
KR100422995B1 (ko) 2004-03-12
IL130083A0 (en) 2000-02-29
PL333920A1 (en) 2000-01-31
CA2698384A1 (en) 1998-06-18
BG103556A (en) 2000-06-30
CA2273917A1 (en) 1998-06-18
JP4272261B2 (ja) 2009-06-03
KR20040004476A (ko) 2004-01-13
TR199901904T2 (xx) 1999-10-21
CN1245496A (zh) 2000-02-23
ATE227717T1 (de) 2002-11-15
ES2189003T3 (es) 2003-07-01
NO992705D0 (no) 1999-06-03
JP2009143924A (ja) 2009-07-02
DE69717148D1 (de) 2002-12-19
HUP0001110A2 (hu) 2001-04-28
DE69717148T2 (de) 2003-10-02
EP0950057B1 (en) 2002-11-13
NZ335810A (en) 2001-03-30
BG64196B1 (bg) 2004-04-30
BR9714677A (pt) 2000-10-03
SK75999A3 (en) 2000-05-16
WO1998025920A1 (en) 1998-06-18
KR100472154B1 (ko) 2005-02-21
CA2273917C (en) 2010-05-25
JP5364872B2 (ja) 2013-12-11
AU733881B2 (en) 2001-05-31
AU5601098A (en) 1998-07-03
CN1125064C (zh) 2003-10-22
HUP0001110A3 (en) 2002-04-29
CA2698384C (en) 2012-05-01
EP0950057A1 (en) 1999-10-20
PT950057E (pt) 2003-04-30

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application