[go: up one dir, main page]

NO991563D0 - N-substituerte azaheterosykliske forbindelser - Google Patents

N-substituerte azaheterosykliske forbindelser

Info

Publication number
NO991563D0
NO991563D0 NO991563A NO991563A NO991563D0 NO 991563 D0 NO991563 D0 NO 991563D0 NO 991563 A NO991563 A NO 991563A NO 991563 A NO991563 A NO 991563A NO 991563 D0 NO991563 D0 NO 991563D0
Authority
NO
Norway
Prior art keywords
substituted azaheterocyclic
azaheterocyclic compounds
compounds
substituted
azaheterocyclic
Prior art date
Application number
NO991563A
Other languages
English (en)
Other versions
NO991563L (no
Inventor
Tine Krogh Jorgensen
Rolf Hohlweg
Peter Madsen
Knud Erik Andersen
Svend Treppendahl
Uffe Bang Olsen
Zdenek Polivka
Alexandra Silhankova
Karel Sindelar
Vladimir Valenta
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of NO991563D0 publication Critical patent/NO991563D0/no
Publication of NO991563L publication Critical patent/NO991563L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Hydrogenated Pyridines (AREA)
NO991563A 1996-10-04 1999-03-30 N-substituerte, azaheterosykliske forbindelser NO991563L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK108996 1996-10-04
PCT/DK1997/000421 WO1998015546A1 (en) 1996-10-04 1997-10-02 N-substituted azaheterocyclic compounds

Publications (2)

Publication Number Publication Date
NO991563D0 true NO991563D0 (no) 1999-03-30
NO991563L NO991563L (no) 1999-06-03

Family

ID=8100875

Family Applications (1)

Application Number Title Priority Date Filing Date
NO991563A NO991563L (no) 1996-10-04 1999-03-30 N-substituerte, azaheterosykliske forbindelser

Country Status (14)

Country Link
US (1) US6569849B1 (no)
EP (1) EP0934306A1 (no)
JP (1) JP2001501629A (no)
KR (1) KR20000048909A (no)
CN (1) CN1234797A (no)
AU (1) AU741839B2 (no)
BR (1) BR9712202A (no)
CA (1) CA2267500A1 (no)
CZ (1) CZ114199A3 (no)
HU (1) HUP0000088A3 (no)
IL (1) IL129122A0 (no)
NO (1) NO991563L (no)
PL (1) PL332593A1 (no)
WO (1) WO1998015546A1 (no)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6509346B2 (en) 1998-01-21 2003-01-21 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
AU2335699A (en) * 1998-01-21 1999-08-09 Kyowa Hakko Kogyo Co. Ltd. Chemokine receptor antagonists and methods of use therefor
US6613905B1 (en) 1998-01-21 2003-09-02 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
EP1049700B9 (en) 1998-01-21 2006-05-10 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US7271176B2 (en) 1998-09-04 2007-09-18 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use thereof
US7355042B2 (en) * 2001-10-16 2008-04-08 Hypnion, Inc. Treatment of CNS disorders using CNS target modulators
US7541365B2 (en) 2001-11-21 2009-06-02 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
TW200301698A (en) 2001-12-21 2003-07-16 Bristol Myers Squibb Co Acridone inhibitors of IMPDH enzyme
TWI291467B (en) 2002-11-13 2007-12-21 Millennium Pharm Inc CCR1 antagonists and methods of use therefor
WO2004112705A2 (en) * 2003-06-16 2004-12-29 Hypnion, Inc. Methods for treating sleep disorders
WO2005020913A2 (en) * 2003-08-25 2005-03-10 Combinatorx, Incorporated Formulations, conjugates, and combinations of drugs for the treatment of neoplasms
RS53277B (sr) * 2006-06-28 2014-08-29 Amgen Inc. Inhibitori transportera-1 glicina
US8034940B2 (en) 2006-08-09 2011-10-11 Bristol-Myers Squibb Company Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
SE531698C2 (sv) 2007-07-12 2009-07-07 Respiratorius Ab Nya bronkdilaterande a,b-omättade amider
US20090215643A1 (en) 2007-07-26 2009-08-27 Cellay, Llc Highly Visible Chromosome-Specific Probes and Related Methods
US9162980B2 (en) 2009-01-09 2015-10-20 Board Of Regents Of The University Of Texas System Anti-depression compounds
US8362277B2 (en) 2009-01-09 2013-01-29 Board Of Regents Of The University Of Texas System Pro-neurogenic compounds
BRPI1006825A2 (pt) 2009-01-09 2019-04-24 Univ Texas compostos pró-neurogênicos
US20130203055A1 (en) 2010-06-03 2013-08-08 Joan Aurich-Costa Methods and kits for in situ detection of nucleotide sequences
JP6126528B2 (ja) 2010-07-07 2017-05-10 ザ・ボード・オブ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・テキサス・システムThe Board Of Regents Of The University Of Texas System 神経新生促進化合物
WO2013026455A1 (en) * 2011-08-24 2013-02-28 Aarhus Universitet Permanently positively charged antidepressants
WO2013090386A2 (en) 2011-12-12 2013-06-20 Cellay, Inc. Methods and kits for room temperature in situ detection of a target nucleic acid in a biological sample
CA2882826A1 (en) * 2012-08-24 2014-02-27 Board Of Regents Of The University Of Texas System Pro-neurogenic compounds
JP2015536651A (ja) 2012-10-31 2015-12-24 セレー,インコーポレイテッド インサイチュハイブリダイゼーションを行うための方法およびキット
CA2929932A1 (en) 2013-11-07 2015-05-14 Cellay, Inc. Methods and kits for detecting a prostate carcinoma and predicting disease outcomes for prostate cancers
WO2015070234A2 (en) 2013-11-11 2015-05-14 Board Of Regents Of The University Of Texas System Neuroprotective compounds and use thereof
WO2015070237A1 (en) 2013-11-11 2015-05-14 Board Of Regents Of The University Of Texas System Neuroprotective chemicals and methods for identifying and using same
CN111171006B (zh) * 2020-01-29 2023-05-12 成都睿智化学研究有限公司 一种3-取代亚氨基二苄氨基类化合物的工艺方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3123610A (en) * 1964-03-03 Alkanoylpiperidinoalkyl
US3058979A (en) * 1957-05-13 1962-10-16 Smith Kline French Lab New perfluoroalkylphenothiazine derivatives
FR1212031A (fr) * 1957-10-21 1960-03-21 Rhone Poulenc Sa Dérivés de la phénothiazine substitués à l'azote par une chaîne basique comportant un hétérocycle et leur préparation
BE566958A (no) * 1958-04-19
CH374682A (de) * 1959-08-28 1964-01-31 Geigy Ag J R Verfahren zur Herstellung von neuen N-heterocyclischen Verbindungen
FR1578748A (no) * 1967-12-28 1969-08-22
AT288414B (de) * 1968-04-20 1971-03-10 Egyt Gyogyszervegyeszeti Gyar Verfahren zur Herstellung von N-heterocyclischen Verbindungen und ihren Salzen
NO127151B (no) * 1969-03-28 1973-05-14 Ciba Geigy Ag
FR2005201B1 (no) * 1969-05-20 1973-03-16 Auguil Ste Civile
GB1323659A (en) * 1971-04-10 1973-07-18 Yoshitomi Pharmaceutical Piperazine derivatives methods for their production and pharmaceuticl compositions containing them
US3828034A (en) * 1972-05-25 1974-08-06 Syntex Inc Tricyclic pharmacological agents,intermediates and methods of making
FR2186249A1 (en) * 1972-05-31 1974-01-11 Synthelabo Phenyl piperazinoalkyl (dihydro)dibenzazepines - antidepressants having low toxicity
US3965181A (en) * 1973-07-06 1976-06-22 Syntex (U.S.A.) Inc. Tricyclic pharmacological agents, intermediates and methods of making
GB1480593A (en) * 1973-11-30 1977-07-20 Kefalas As Xanthene and thioxanthene derivatives having pharmaceutical activity
DE3444837A1 (de) * 1984-12-08 1986-06-12 Basf Ag, 6700 Ludwigshafen 10,11-dihydro-5h-dibenzo(a,d)cycloheptadien- derivate, ihre herstellung und verwendung
MY113463A (en) * 1994-01-04 2002-03-30 Novo Nordisk As Novel heterocyclic compounds
US5716949A (en) * 1995-04-07 1998-02-10 Novo Nordisk A/S Heterocyclic compounds
DE69720021T2 (de) * 1996-10-04 2004-02-05 Novo Nordisk A/S 1,4-disubstituierte piperazine
US6040318A (en) * 1997-06-25 2000-03-21 Novo Nordisk A/S Tricycle substituted with azaheterocyclic carboxylic acids

Also Published As

Publication number Publication date
WO1998015546A1 (en) 1998-04-16
CN1234797A (zh) 1999-11-10
NO991563L (no) 1999-06-03
KR20000048909A (ko) 2000-07-25
AU741839B2 (en) 2001-12-13
JP2001501629A (ja) 2001-02-06
HUP0000088A2 (hu) 2000-06-28
PL332593A1 (en) 1999-09-27
IL129122A0 (en) 2000-02-17
US6569849B1 (en) 2003-05-27
CZ114199A3 (cs) 1999-09-15
HUP0000088A3 (en) 2000-09-28
CA2267500A1 (en) 1998-04-16
EP0934306A1 (en) 1999-08-11
AU4377197A (en) 1998-05-05
BR9712202A (pt) 1999-08-31

Similar Documents

Publication Publication Date Title
NO991563D0 (no) N-substituerte azaheterosykliske forbindelser
DE69729947T2 (de) N-substituierte 2-cyanopyrrolidine
DE69927844D1 (de) N-substituierte 2-cyanopyrrolidine
BR9612465A (pt) Compostos heterocíclicos
EE200000031A (et) Uued spiroasabitsüklilised heterotsüklilised ühendid
FI962749L (fi) Uusia heterosyklisiä yhdisteitä
FI973207A7 (fi) Heterosyklisiä yhdisteitä
DK0820451T3 (da) Hidtil ukendte heterocykliske forbindelser
NO991564D0 (no) N-substituerte azaheterosykliske forbindelser
DE69531522D1 (de) Heterozyklische Verbindungen
FI961844L (fi) Fenyyli-indoliyhdisteitä
BR9503042A (pt) Composto de polialquilpiperidina
DE59811182D1 (de) Heterocyclische Verbindungen
DE50003014D1 (de) N-substituierte perhydrodiazine
AU4376997A (en) N-substituted azaheterocyclic compounds
DK0937040T3 (da) N-substituerede 2-cyanopyrrolidiner
SE9402122D0 (sv) Heterocyclic compounds
SE9400968D0 (sv) Heterocyclic compounds
DK0851865T3 (da) Hidtil ukendte heterocykliske forbindelser
FIU960481U0 (fi) Pakkaus joulukuusta varten

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application