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NO995075L - Steroid-sulfataseinhibitorer - Google Patents

Steroid-sulfataseinhibitorer

Info

Publication number
NO995075L
NO995075L NO995075A NO995075A NO995075L NO 995075 L NO995075 L NO 995075L NO 995075 A NO995075 A NO 995075A NO 995075 A NO995075 A NO 995075A NO 995075 L NO995075 L NO 995075L
Authority
NO
Norway
Prior art keywords
sub
compound
enzyme
sulphate
steroid sulphatase
Prior art date
Application number
NO995075A
Other languages
English (en)
Other versions
NO995075D0 (no
NO308903B1 (no
Inventor
Michael John Reed
Barry Victor Lloyd Potter
Original Assignee
Sterix Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of NO995075L publication Critical patent/NO995075L/no
Application filed by Sterix Ltd filed Critical Sterix Ltd
Publication of NO995075D0 publication Critical patent/NO995075D0/no
Publication of NO308903B1 publication Critical patent/NO308903B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30Oestrogens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32Antioestrogens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36Antigestagens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0072Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Surgical Instruments (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO995075A 1991-08-29 1999-10-18 Steroid-sulfataseinhibitorer NO308903B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919118478A GB9118478D0 (en) 1991-08-29 1991-08-29 Steroid sulphatase inhibitors
PCT/GB1992/001587 WO1993005064A1 (en) 1991-08-29 1992-08-28 Steroid sulphatase inhibitors

Publications (3)

Publication Number Publication Date
NO995075L true NO995075L (no) 1994-04-29
NO995075D0 NO995075D0 (no) 1999-10-18
NO308903B1 NO308903B1 (no) 2000-11-13

Family

ID=10700604

Family Applications (6)

Application Number Title Priority Date Filing Date
NO940635A NO307301B1 (no) 1991-08-29 1994-02-24 Anvendelse av en forbindelse for fremstilling av et medikament for å inhibere steroidsulfataseaktivitet
NO995075A NO308903B1 (no) 1991-08-29 1999-10-18 Steroid-sulfataseinhibitorer
NO995076A NO308774B1 (no) 1991-08-29 1999-10-18 Farmasøytisk preparat
NO20002595A NO314287B1 (no) 1991-08-29 2000-05-19 Anvendelse av en ringsystemforbindelse for fremstilling av et medikament
NO20025725A NO318009B1 (no) 1991-08-29 2002-11-28 Forbindelse, farmasoytisk preparat inneholdende den samme samt anvendelse derav
NO20044458A NO20044458L (no) 1991-08-29 2004-10-20 Anvendelse av en ringsystemforbindelse for fremstilling av et medikament

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO940635A NO307301B1 (no) 1991-08-29 1994-02-24 Anvendelse av en forbindelse for fremstilling av et medikament for å inhibere steroidsulfataseaktivitet

Family Applications After (4)

Application Number Title Priority Date Filing Date
NO995076A NO308774B1 (no) 1991-08-29 1999-10-18 Farmasøytisk preparat
NO20002595A NO314287B1 (no) 1991-08-29 2000-05-19 Anvendelse av en ringsystemforbindelse for fremstilling av et medikament
NO20025725A NO318009B1 (no) 1991-08-29 2002-11-28 Forbindelse, farmasoytisk preparat inneholdende den samme samt anvendelse derav
NO20044458A NO20044458L (no) 1991-08-29 2004-10-20 Anvendelse av en ringsystemforbindelse for fremstilling av et medikament

Country Status (25)

Country Link
US (3) US5616574A (no)
EP (6) EP1522543A1 (no)
JP (6) JP3219408B2 (no)
KR (4) KR100258396B1 (no)
AT (5) ATE237333T1 (no)
AU (2) AU689043B2 (no)
BR (1) BR9206434A (no)
CA (4) CA2114630C (no)
CY (4) CY2253B1 (no)
CZ (1) CZ295939B6 (no)
DE (5) DE69231280T2 (no)
DK (4) DK0982032T3 (no)
ES (4) ES2204059T3 (no)
FI (5) FI940903A7 (no)
GB (1) GB9118478D0 (no)
GE (6) GEP20022766B (no)
GR (1) GR3034579T3 (no)
HU (1) HUT66097A (no)
LV (1) LV12618B (no)
NO (6) NO307301B1 (no)
RU (4) RU2182152C2 (no)
SG (7) SG106116A1 (no)
SK (4) SK282187B6 (no)
UA (4) UA41875C2 (no)
WO (1) WO1993005064A1 (no)

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US6903084B2 (en) * 1991-08-28 2005-06-07 Sterix Limited Steroid sulphatase inhibitors
GB9603325D0 (en) 1996-02-16 1996-04-17 Imperial College A compound
US6476011B1 (en) 1991-08-28 2002-11-05 Sterix Limited Methods for introducing an estrogenic compound
AU2112995A (en) * 1994-04-05 1995-10-23 Celltech Therapeutics Limited Use of estrone derivatives as steroid sulphatase inhibitors
DE4429398C2 (de) * 1994-08-09 1997-09-11 Jenapharm Gmbh Verwendung von Estra-1,3,5(10)-trien-Derivaten zur hormonalen Kontrazeption
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US6921776B1 (en) 1996-02-16 2005-07-26 Sterix Limited Compound
US6506792B1 (en) 1997-03-04 2003-01-14 Sterix Limited Compounds that inhibit oestrone sulphatase and/or aromatase and methods for making and using
ATE286038T1 (de) * 1996-03-05 2005-01-15 Sterix Ltd Verbindungen mit sulfonsäure-amidgruppe
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US6642220B1 (en) 1996-12-05 2003-11-04 Sterix Limited Compounds that inhibit oestrone sulphatase; compositions thereof; and methods employing the same
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US6376687B1 (en) 1997-07-18 2002-04-23 Duquesne University Of The Holy Ghost Steroid sulfatase inhibitors and methods for making and using the same
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US6248780B1 (en) 1998-10-01 2001-06-19 Duquesne University Of The Holy Ghost Compounds for the treatment of estrogen-dependent illnesses and methods for making and using the same
US6667299B1 (en) 2000-03-16 2003-12-23 Hollis-Eden Pharmaceuticals, Inc. Pharmaceutical compositions and treatment methods
WO2000053620A1 (en) * 1999-03-10 2000-09-14 Nippon Organon K. K. Novel estradiol derivatives
JP2000309599A (ja) 1999-04-13 2000-11-07 Kyowa Hakko Kogyo Co Ltd エストラ−1,3,5(10),16−テトラエン誘導体
US7078395B1 (en) 1999-06-16 2006-07-18 Sterix Limited Methods for treating or preventing cancer by preventing, inhibiting or arresting cell cycling
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US6583130B1 (en) 1999-09-13 2003-06-24 Schering Ag C13-substituted estra-1,3,5,(10)-trien-3-yl sulfamates, methods of preparing same, and pharmaceutical compositions containing these compounds
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US7335650B2 (en) 2000-01-14 2008-02-26 Sterix Limited Composition
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EP1406634A1 (en) 2001-07-13 2004-04-14 Schering Aktiengesellschaft Combination of drospirenone and an estrogen sulphamate for hrt
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GB0624105D0 (en) * 2006-12-01 2007-01-10 Sterix Ltd Use
GB0706072D0 (en) 2007-03-28 2007-05-09 Sterix Ltd Compound
JP5543920B2 (ja) 2007-09-17 2014-07-09 プレグレム エスアー 閉経前の女性におけるエストロゲン依存症状の治療
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Also Published As

Publication number Publication date
US6159960A (en) 2000-12-12
ATE237333T1 (de) 2003-05-15
KR100321018B1 (ko) 2002-03-20
KR100322650B1 (ko) 2002-03-20
JP3581821B2 (ja) 2004-10-27
RU2182152C2 (ru) 2002-05-10
DE69231280D1 (de) 2000-08-24
FI20050991L (fi) 2005-10-03
GEP20022802B (en) 2002-09-25
CA2305749A1 (en) 1993-03-18
US5830886A (en) 1998-11-03
DE69233149T2 (de) 2004-06-24
ES2204059T3 (es) 2004-04-16
NO20025725D0 (no) 2002-11-28
FI20002260A7 (fi) 2000-10-13
DK0921130T3 (da) 2003-07-21
GR3034579T3 (en) 2001-01-31
EP1522543A1 (en) 2005-04-13
GEP20063773B (en) 2006-03-27
NO940635D0 (no) 1994-02-24
NO20044458L (no) 1994-04-29
US5616574A (en) 1997-04-01
NO940635L (no) 1994-04-29
SK282186B6 (sk) 2001-12-03
FI20002259A7 (fi) 2000-10-13
CZ44094A3 (en) 1995-01-18
CY2397B1 (en) 2004-09-10
DE69233020T2 (de) 2003-11-06
GEP20022766B (en) 2002-08-26
HK1020672A1 (en) 2000-05-19
JP2003176297A (ja) 2003-06-24
FI940903A0 (fi) 1994-02-25
EP0641355B1 (en) 2000-07-19
LV12618B (en) 2001-07-20
JP3581820B2 (ja) 2004-10-27
NO995075D0 (no) 1999-10-18
NO2595A (no) 1994-04-29
DE69233431T2 (de) 2006-02-23
EP0928609A2 (en) 1999-07-14
GEP20022637B (en) 2002-02-25
SG88782A1 (en) 2002-05-21
UA70957C2 (uk) 2004-11-15
DK0982032T3 (da) 2003-11-03
EP0982032A3 (en) 2002-03-20
FI20002260L (fi) 2000-10-13
RU2207134C2 (ru) 2003-06-27
SG88783A1 (en) 2002-05-21
CA2114630C (en) 2003-09-30
AU689043B2 (en) 1998-03-19
ATE246706T1 (de) 2003-08-15
AU717116B2 (en) 2000-03-16
FI20002261L (fi) 2000-10-13
HK1025051A1 (en) 2000-11-03
DE69233053D1 (de) 2003-06-12
HK1019753A1 (en) 2000-02-25
ES2148178T3 (es) 2000-10-16
SG103820A1 (en) 2004-05-26
NO20002595D0 (no) 2000-05-19
KR100258396B1 (ko) 2000-08-01
CA2114630A1 (en) 1993-03-18
SG103374A1 (en) 2004-04-29
EP1099706A2 (en) 2001-05-16
SK282187B6 (sk) 2001-12-03
NO308774B1 (no) 2000-10-30
JP2002255993A (ja) 2002-09-11
JP3219408B2 (ja) 2001-10-15
EP0982032B1 (en) 2003-08-06
GEP20033094B (en) 2003-10-27
FI20050991A7 (fi) 2005-10-03
EP0928609A3 (en) 2001-11-07
FI940903A7 (fi) 1994-04-20
NO995076L (no) 1994-04-29
CA2305758A1 (en) 1993-03-18
ES2196483T3 (es) 2003-12-16
BR9206434A (pt) 1994-09-27
ES2193475T3 (es) 2003-11-01
CZ295939B6 (cs) 2005-12-14
AU1007799A (en) 1999-03-04
SK282189B6 (sk) 2001-12-03
UA41875C2 (uk) 2001-10-15
NO307301B1 (no) 2000-03-13
SG115508A1 (en) 2005-10-28
SG106116A1 (en) 2004-09-30
NO308903B1 (no) 2000-11-13
RU94019334A (ru) 1996-10-20
UA70958C2 (uk) 2004-11-15
JP2000355598A (ja) 2000-12-26
EP0921130B1 (en) 2003-05-07
NO20025725L (no) 1994-04-29
CY2253B1 (en) 2003-07-04
GEP20022803B (en) 2002-09-25
DE69233053T2 (de) 2003-11-20
NO318009B1 (no) 2005-01-17
GB9118478D0 (en) 1991-10-16
SK282188B6 (sk) 2001-12-03
EP0921130A3 (en) 2001-09-05
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