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NO994931L - Chelateringsmidler - Google Patents

Chelateringsmidler

Info

Publication number
NO994931L
NO994931L NO994931A NO994931A NO994931L NO 994931 L NO994931 L NO 994931L NO 994931 A NO994931 A NO 994931A NO 994931 A NO994931 A NO 994931A NO 994931 L NO994931 L NO 994931L
Authority
NO
Norway
Prior art keywords
different
same
moiety
optionally substituted
hydrogen
Prior art date
Application number
NO994931A
Other languages
English (en)
Other versions
NO994931D0 (no
Inventor
Shi-Bao Yu
Jasbir Singh
Louise Golding
Original Assignee
Nycomed Imaging As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Imaging As filed Critical Nycomed Imaging As
Publication of NO994931D0 publication Critical patent/NO994931D0/no
Publication of NO994931L publication Critical patent/NO994931L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/103—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being acyclic, e.g. DTPA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Radiology & Medical Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Det er beskrevet en kompleksanvendende forbindelse med formel (I): RS(CR)N(R),(CR)X(CR)N(R)i(CR)SR, (hvor hver n, som kan være lik eller forskjellig, er et tall 2, 3 eller 4 (fortrinnsvis 2); hver i, som kan være lik eller forskjellig, er 0 eller 1; hver R, som kan være lik eller forskjellig, er H eller en tiol beskyttelses ruppe, fortrinnsvis en bekyttelsesgruppe; X er = O, S, N, NReller en substituert fosforgruppe (f.eks. oksosubstituert fosfor), fortrinnsvis S eller N; hver R, som kan være lik eller forskjellig, er hydrogen eller en eventuelt substituert organisk gn.ppe; hver R, som kan være lik eller forskjellig, er hydrogen eller en eventuelt substituert organisk gruppe; hver R, som kan være lik eller forskjellig, er hydrogen eller en eventuelt substituert organisk gruppe, eller en del CRkan være en karbonylgruppe eller to, tre eller fire RS på to forskjellige karboner sammen med disse karbonene, og hvilke som helst mellomliggende atomer kan representere en eventuelt subsituert mettet eller umettet homocyklisk eller heterocyklisk ring; og fortrinnsvis, minst en CRgruppe er forskjellig fra CHeller CH(CH)) eller et salt eller kompleks derav, hvor eventuelt minst en av R, R, R3 og Rgruppene er koblet direkte eller indirekte til en vektor gruppe.
NO994931A 1997-04-11 1999-10-08 Chelateringsmidler NO994931L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/833,995 US6004529A (en) 1997-04-11 1997-04-11 Chelating agents
PCT/GB1998/001078 WO1998046276A1 (en) 1997-04-11 1998-04-14 Chelating agents

Publications (2)

Publication Number Publication Date
NO994931D0 NO994931D0 (no) 1999-10-08
NO994931L true NO994931L (no) 1999-12-08

Family

ID=25265829

Family Applications (1)

Application Number Title Priority Date Filing Date
NO994931A NO994931L (no) 1997-04-11 1999-10-08 Chelateringsmidler

Country Status (12)

Country Link
US (2) US6004529A (no)
EP (1) EP0973554B1 (no)
JP (1) JP2001521515A (no)
KR (1) KR20010006210A (no)
AT (1) ATE298254T1 (no)
AU (1) AU740759B2 (no)
BR (1) BR9808672A (no)
CA (1) CA2286790A1 (no)
DE (1) DE69830653T2 (no)
IL (1) IL132225A0 (no)
NO (1) NO994931L (no)
WO (1) WO1998046276A1 (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6004529A (en) 1997-04-11 1999-12-21 Nycomed Imaging As Chelating agents
US7405320B2 (en) * 1998-06-22 2008-07-29 Immunomedics, Inc. Therapeutic and diagnostic conjugates for use with multispecific antibodies
US6248222B1 (en) * 1998-09-08 2001-06-19 Acm Research, Inc. Methods and apparatus for holding and positioning semiconductor workpieces during electropolishing and/or electroplating of the workpieces
US6623655B1 (en) 2000-04-24 2003-09-23 Sigma-Aldrich Co. Metal chelating compositions
AU2000246082A1 (en) 2000-05-21 2001-12-03 Transscan Medical Ltd. Apparatus for impedance imaging coupled with another modality
CN115028561B (zh) * 2022-06-16 2023-12-22 江西省科学院应用化学研究所 硫代二甘酰胺酸类萃取剂及其制备方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2122431C1 (ru) * 1992-05-07 1998-11-27 Никомед Имеджинг Ас Радиоактивный иммунореагент направленного действия, композиция для получения изображения злокачественного новообразования в организме, способ получения изображения и комплексообразующий агент
AU5019193A (en) * 1992-08-19 1994-03-15 Mallinckrodt Medical, Inc. Ligands for ga-68 pet heart applications
US5608110A (en) * 1993-06-15 1997-03-04 Bracco International B.V. Heteroatom-bearing ligands and metal complexes thereof
US5443953A (en) * 1993-12-08 1995-08-22 Immunomedics, Inc. Preparation and use of immunoconjugates
US5632969A (en) * 1994-10-13 1997-05-27 Merck & Co., Inc. N3 S2 chelating ligands optionally radiolabelled with Tc or Re, useful for diagnostic or therapeutic applications
US6004529A (en) 1997-04-11 1999-12-21 Nycomed Imaging As Chelating agents

Also Published As

Publication number Publication date
CA2286790A1 (en) 1998-10-22
EP0973554A1 (en) 2000-01-26
DE69830653D1 (en) 2005-07-28
ATE298254T1 (de) 2005-07-15
KR20010006210A (ko) 2001-01-26
NO994931D0 (no) 1999-10-08
WO1998046276A1 (en) 1998-10-22
WO1998046276A8 (en) 1999-07-22
BR9808672A (pt) 2000-07-11
US6004529A (en) 1999-12-21
IL132225A0 (en) 2001-03-19
AU7059798A (en) 1998-11-11
US6280706B1 (en) 2001-08-28
DE69830653T2 (de) 2006-05-04
AU740759B2 (en) 2001-11-15
JP2001521515A (ja) 2001-11-06
EP0973554B1 (en) 2005-06-22

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application