NO994160L - Basic aluminum magnesium carbonate, process for its preparation and its use as a pharmaceutical preparation for the treatment of gastric acidity - Google Patents
Basic aluminum magnesium carbonate, process for its preparation and its use as a pharmaceutical preparation for the treatment of gastric acidityInfo
- Publication number
- NO994160L NO994160L NO994160A NO994160A NO994160L NO 994160 L NO994160 L NO 994160L NO 994160 A NO994160 A NO 994160A NO 994160 A NO994160 A NO 994160A NO 994160 L NO994160 L NO 994160L
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- magnesium carbonate
- whose
- aluminum magnesium
- basic aluminum
- Prior art date
Links
- UJOHNXQDVUADCG-UHFFFAOYSA-L aluminum;magnesium;carbonate Chemical compound [Mg+2].[Al+3].[O-]C([O-])=O UJOHNXQDVUADCG-UHFFFAOYSA-L 0.000 title abstract 2
- 230000002496 gastric effect Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical class [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 abstract 1
- 238000002441 X-ray diffraction Methods 0.000 abstract 1
- 229940069428 antacid Drugs 0.000 abstract 1
- 239000003159 antacid agent Substances 0.000 abstract 1
- 230000001458 anti-acid effect Effects 0.000 abstract 1
- 238000007707 calorimetry Methods 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000002425 crystallisation Methods 0.000 abstract 1
- 230000008025 crystallization Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000002178 gastroprotective effect Effects 0.000 abstract 1
- 238000002329 infrared spectrum Methods 0.000 abstract 1
- 238000001228 spectrum Methods 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01F—COMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM, CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THE RARE-EARTH METALS
- C01F7/00—Compounds of aluminium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/10—Carbonates; Bicarbonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01F—COMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM, CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THE RARE-EARTH METALS
- C01F7/00—Compounds of aluminium
- C01F7/78—Compounds containing aluminium, with or without oxygen or hydrogen, and containing two or more other elements
- C01F7/784—Layered double hydroxide, e.g. comprising nitrate, sulfate or carbonate ions as intercalating anions
- C01F7/785—Hydrotalcite
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
- C01P2002/00—Crystal-structural characteristics
- C01P2002/70—Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data
- C01P2002/72—Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data by d-values or two theta-values, e.g. as X-ray diagram
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
- C01P2002/00—Crystal-structural characteristics
- C01P2002/70—Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data
- C01P2002/77—Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data by unit-cell parameters, atom positions or structure diagrams
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
- C01P2002/00—Crystal-structural characteristics
- C01P2002/80—Crystal-structural characteristics defined by measured data other than those specified in group C01P2002/70
- C01P2002/82—Crystal-structural characteristics defined by measured data other than those specified in group C01P2002/70 by IR- or Raman-data
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
- C01P2002/00—Crystal-structural characteristics
- C01P2002/80—Crystal-structural characteristics defined by measured data other than those specified in group C01P2002/70
- C01P2002/88—Crystal-structural characteristics defined by measured data other than those specified in group C01P2002/70 by thermal analysis data, e.g. TGA, DTA, DSC
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
- C01P2004/00—Particle morphology
- C01P2004/50—Agglomerated particles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Inorganic Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Geology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
Abstract
Det er beskrevet et nytt basisk aluminium-magnesiumkarbonat av formelen (I) og med rhombohedrisk krystallisasjon, hvis nettparametre er a=b=3,046 Å, c-22,79 Å, a=B=90°; y=120° og cellevolum = 183 Å3, hvis røntgendiffraksjonsspektrum viser følgende d(Å) verdier: 7,597; 3,798; 2,6202; 2,5698; 2,5322; 2,2830, 1,93545, 1,72447; l 623930; 1,52289; 1,49318; 1,46002; 1,41351; 1,38528 og 1,31011; hvis infrarøde spektrum viser karakteristiske bånd ved 1361, 785 og 449 cm'1 (figur 1) og hvis differensielle sveipkalorimetri (DSC) er vist i figur 2. Denne forbindelsen anvendes som terapeutisk middel som et antacid og gastro- beskyttende middel.There is disclosed a new basic aluminum magnesium carbonate of formula (I) and with rhombohedric crystallization, whose mesh parameters are a = b = 3.046 Å, c-22.79 Å, a = B = 90 °; y = 120 ° and cell volume = 183 Å3, whose X-ray diffraction spectrum shows the following d (Å) values: 7.597; 3798; 2.6202; 2.5698; 2.5322; 2.2830, 1.93545, 1.72447; l 623930; 1.52289; 1.49318; 1.46002; 1.41351; 1.38528 and 1.31011; whose infrared spectrum shows characteristic bands at 1361, 785 and 449 cm -1 (Figure 1) and whose differential sweep calorimetry (DSC) is shown in Figure 2. This compound is used as a therapeutic agent as an antacid and gastroprotective agent.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES009702717A ES2133136B1 (en) | 1997-12-30 | 1997-12-30 | NEW BASIC ALBUMINUM AND MAGNESIUM CARBONATE. |
| PCT/EP1998/008498 WO1999035088A1 (en) | 1997-12-30 | 1998-12-29 | Basic aluminum magnesium carbonate, method for the preparation thereof and its use as a pharmaceutical composition for treating stomach acidity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO994160D0 NO994160D0 (en) | 1999-08-27 |
| NO994160L true NO994160L (en) | 1999-08-27 |
Family
ID=8301660
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO994160A NO994160L (en) | 1997-12-30 | 1999-08-27 | Basic aluminum magnesium carbonate, process for its preparation and its use as a pharmaceutical preparation for the treatment of gastric acidity |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0968133A1 (en) |
| JP (1) | JP2001516328A (en) |
| KR (1) | KR20000075839A (en) |
| AR (1) | AR007232A1 (en) |
| AU (1) | AU742544B2 (en) |
| BR (1) | BR9807275A (en) |
| CA (1) | CA2282361A1 (en) |
| ES (1) | ES2133136B1 (en) |
| IL (1) | IL131573A0 (en) |
| NO (1) | NO994160L (en) |
| PA (1) | PA8464401A1 (en) |
| PL (1) | PL335464A1 (en) |
| RU (1) | RU2168464C1 (en) |
| WO (1) | WO1999035088A1 (en) |
| ZA (1) | ZA9811216B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4338470B2 (en) * | 2003-08-12 | 2009-10-07 | 日鉄鉱業株式会社 | Hydrotalcite particles and method for producing the same |
| CN101039875B (en) * | 2004-10-20 | 2012-03-07 | 堺化学工业株式会社 | Hydrotalcite and synthetic resin composition |
| RU2540635C2 (en) * | 2012-11-22 | 2015-02-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Национальный минерально-сырьевой университет "Горный" | Production of alkaline metal hydrocarboaluminate from natural magnesium-bearing stock |
| CN108159072A (en) * | 2017-12-04 | 2018-06-15 | 上海裕英生物医药科技有限公司 | The preparation process of almagate |
| RU2678007C1 (en) * | 2017-12-05 | 2019-01-22 | Федеральное государственное бюджетное учреждение науки Федеральный исследовательский центр "Кольский научный центр Российской академии наук" (ФИЦ КНЦ РАН) | Method of obtaining layered hydroxide of magnesium and aluminum |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3539306A (en) * | 1966-07-25 | 1970-11-10 | Kyowa Chem Ind Co Ltd | Process for the preparation of hydrotalcite |
| US4904457A (en) * | 1974-03-30 | 1990-02-27 | Aluminum Company Of America | Synthetic hydrotalcite |
| GB1598375A (en) * | 1978-02-17 | 1981-09-16 | Anphar Sa | Aluminium magnesium carbonate |
| DE3306822C2 (en) * | 1983-02-26 | 1985-01-03 | Giulini Chemie Gmbh, 6700 Ludwigshafen | Crystalline, basic aluminum-magnesium carbonate |
| DK167146B1 (en) * | 1990-09-11 | 1993-09-06 | Topsoe Haldor As | METHOD AND CATALYST FOR PRODUCING AROMATIC COMPOUNDS |
| US5364828A (en) * | 1992-10-21 | 1994-11-15 | Minerals Technologies | Spheroidal aggregate of platy synthetic hydrotalcite |
| CZ293606B6 (en) * | 1994-08-15 | 2004-06-16 | Aluminum Company Of America | Process for preparing a layered double hydroxide and hydrotalcite and hydrotalcite-like compounds in the form of a powder |
| DE19503522A1 (en) * | 1995-02-03 | 1996-08-08 | Rwe Dea Ag | Production of mixed layered metal hydroxides and their metal oxides |
-
1997
- 1997-12-30 ES ES009702717A patent/ES2133136B1/en not_active Expired - Lifetime
-
1998
- 1998-12-08 ZA ZA9811216A patent/ZA9811216B/en unknown
- 1998-12-10 PA PA19988464401A patent/PA8464401A1/en unknown
- 1998-12-29 PL PL98335464A patent/PL335464A1/en unknown
- 1998-12-29 EP EP98966416A patent/EP0968133A1/en not_active Withdrawn
- 1998-12-29 RU RU99120777/12A patent/RU2168464C1/en active
- 1998-12-29 BR BR9807275-7A patent/BR9807275A/en unknown
- 1998-12-29 KR KR1019997007914A patent/KR20000075839A/en not_active Ceased
- 1998-12-29 IL IL13157398A patent/IL131573A0/en unknown
- 1998-12-29 JP JP53563199A patent/JP2001516328A/en active Pending
- 1998-12-29 CA CA002282361A patent/CA2282361A1/en not_active Abandoned
- 1998-12-29 AR ARP980106727A patent/AR007232A1/en unknown
- 1998-12-29 WO PCT/EP1998/008498 patent/WO1999035088A1/en not_active Ceased
- 1998-12-29 AU AU22767/99A patent/AU742544B2/en not_active Ceased
-
1999
- 1999-08-27 NO NO994160A patent/NO994160L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO994160D0 (en) | 1999-08-27 |
| AU742544B2 (en) | 2002-01-03 |
| IL131573A0 (en) | 2001-01-28 |
| PA8464401A1 (en) | 2000-09-29 |
| RU2168464C1 (en) | 2001-06-10 |
| WO1999035088A1 (en) | 1999-07-15 |
| KR20000075839A (en) | 2000-12-26 |
| ES2133136A1 (en) | 1999-08-16 |
| PL335464A1 (en) | 2000-04-25 |
| ES2133136B1 (en) | 2000-04-01 |
| AU2276799A (en) | 1999-07-26 |
| JP2001516328A (en) | 2001-09-25 |
| EP0968133A1 (en) | 2000-01-05 |
| ZA9811216B (en) | 1999-07-14 |
| AR007232A1 (en) | 1999-10-27 |
| BR9807275A (en) | 2000-05-02 |
| CA2282361A1 (en) | 1999-07-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |