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NO982100L - Peptid-derivater av Dolastatin 15 og deres anvendelse - Google Patents

Peptid-derivater av Dolastatin 15 og deres anvendelse

Info

Publication number
NO982100L
NO982100L NO982100A NO982100A NO982100L NO 982100 L NO982100 L NO 982100L NO 982100 A NO982100 A NO 982100A NO 982100 A NO982100 A NO 982100A NO 982100 L NO982100 L NO 982100L
Authority
NO
Norway
Prior art keywords
dolastatin
peptide derivatives
new
formula
preparation
Prior art date
Application number
NO982100A
Other languages
English (en)
Other versions
NO982100D0 (no
Inventor
Andreas Kling
Bernd Janssen
Wilhelm Amberg
Andreas Haupt
Kurt Ritter
Ernst Buschmann
Harald Bernard
Stefan Mueller
Thomas Zierke
Teresa Barlozzari
Monika De Arruda
Simon Robinson
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of NO982100D0 publication Critical patent/NO982100D0/no
Publication of NO982100L publication Critical patent/NO982100L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Nye peptider med formelen A-B-D-E-F-L hvori A, B, D, E, F og L har betydningene som er angitt i beskrivelsen, og deres fremstilling er beskrevet. De nye forbindelser er egnet for kontrollering av sykdommer.
NO982100A 1995-11-09 1998-05-08 Peptid-derivater av Dolastatin 15 og deres anvendelse NO982100L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/554,897 US5807984A (en) 1995-11-09 1995-11-09 Oligopeptides, the preparation and use thereof
PCT/EP1996/004709 WO1997017364A1 (en) 1995-11-09 1996-10-30 Peptide derivatives of dolastatin 15 and their use

Publications (2)

Publication Number Publication Date
NO982100D0 NO982100D0 (no) 1998-05-08
NO982100L true NO982100L (no) 1998-05-08

Family

ID=24215159

Family Applications (1)

Application Number Title Priority Date Filing Date
NO982100A NO982100L (no) 1995-11-09 1998-05-08 Peptid-derivater av Dolastatin 15 og deres anvendelse

Country Status (12)

Country Link
US (1) US5807984A (no)
EP (1) EP0859786A1 (no)
JP (1) JPH11515032A (no)
KR (1) KR19990067460A (no)
AU (1) AU729333B2 (no)
BR (1) BR9611383A (no)
CZ (1) CZ139198A3 (no)
HU (1) HUP9900089A3 (no)
MX (1) MX9803662A (no)
NO (1) NO982100L (no)
WO (1) WO1997017364A1 (no)
ZA (1) ZA969402B (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010009901A1 (en) 1996-12-11 2001-07-26 Basf Aktiengesellschaft Germany Antineoplastic peptides
TW474946B (en) * 1995-12-15 2002-02-01 Basf Ag Novel compounds, the preparation and use thereof
US5965537A (en) * 1997-03-10 1999-10-12 Basf Aktiengesellschaft Dolastatin 15 derivatives with carbonyl and heterocyclic functionalities at the C-terminus
US6143721A (en) * 1997-07-18 2000-11-07 Basf Aktiengesellschaft Dolastatin 15 derivatives
WO1999015130A2 (en) * 1997-09-24 1999-04-01 ARIZONA BOARD OF REGENTS, actingon behalf of ARIZ ONA STATE UNIVERSITY Synthetic antineoplastic agents derived from dolastatin 15 and methods of making same
US6686445B1 (en) 1997-09-24 2004-02-03 Arizona Board Of Regents, Acting For And On Behalf Of Arizona State University Synthetic antineoplastic agents derived from dolastatin 15 and methods of making same
FR2774989B1 (fr) * 1998-02-18 2000-03-17 Adir Nouveaux cytotoxiques derives de l'oestradiol
US5985837A (en) * 1998-07-08 1999-11-16 Basf Aktiengesellschaft Dolastatin 15 derivatives
EP1229934B1 (en) 1999-10-01 2014-03-05 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
US20250281630A1 (en) 2021-09-03 2025-09-11 Toray Industries, Inc. Pharmaceutical composition for cancer treatment and/or prevention

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816444A (en) * 1987-07-10 1989-03-28 Arizona Board Of Regents, Arizona State University Cell growth inhibitory substance
US4879278A (en) * 1989-05-16 1989-11-07 Arizona Board Of Regents Isolation and structural elucidation of the cytostatic linear depsipeptide dolastatin 15
EP0934950B1 (en) * 1991-08-09 2002-04-10 Teikoku Hormone Mfg. Co., Ltd. Tetrapeptide derivative
JP3523253B2 (ja) * 1992-05-20 2004-04-26 アボット ゲーエムベーハー ウント カンパニー カーゲー ドラスタチン誘導体
US5831002A (en) * 1992-05-20 1998-11-03 Basf Aktiengesellschaft Antitumor peptides
PL178766B1 (pl) * 1992-12-16 2000-06-30 Basf Ag Nowe peptydy
US5530097A (en) * 1994-08-01 1996-06-25 Arizona Board Of Regents Acting On Behalf Of Arizona State University Human cancer inhibitory peptide amides
US5504191A (en) * 1994-08-01 1996-04-02 Arizona Board Of Regents Acting On Behalf Of Arizona State University Human cancer inhibitory pentapeptide methyl esters

Also Published As

Publication number Publication date
KR19990067460A (ko) 1999-08-16
WO1997017364A1 (en) 1997-05-15
BR9611383A (pt) 1999-01-26
HUP9900089A3 (en) 1999-11-29
US5807984A (en) 1998-09-15
HUP9900089A2 (hu) 1999-05-28
CZ139198A3 (cs) 1998-09-16
ZA969402B (en) 1998-05-08
EP0859786A1 (en) 1998-08-26
JPH11515032A (ja) 1999-12-21
NO982100D0 (no) 1998-05-08
MX9803662A (es) 1998-09-30
AU7495796A (en) 1997-05-29
AU729333B2 (en) 2001-02-01

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application