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NO981394L - Faste legemiddelformer som kan oppnÕs ved ekstrudering av en isomaltholdig polymersmelte som inneholder virkestoff - Google Patents

Faste legemiddelformer som kan oppnÕs ved ekstrudering av en isomaltholdig polymersmelte som inneholder virkestoff

Info

Publication number
NO981394L
NO981394L NO981394A NO981394A NO981394L NO 981394 L NO981394 L NO 981394L NO 981394 A NO981394 A NO 981394A NO 981394 A NO981394 A NO 981394A NO 981394 L NO981394 L NO 981394L
Authority
NO
Norway
Prior art keywords
extrusion
isomalt
active ingredient
polymer melt
solid pharmaceutical
Prior art date
Application number
NO981394A
Other languages
English (en)
Other versions
NO981394D0 (no
Inventor
Juergen Zeidler
Joerg Rosenberg
Jaerg Neumann
Jaerg Breitenbach
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of NO981394L publication Critical patent/NO981394L/no
Publication of NO981394D0 publication Critical patent/NO981394D0/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Oppfinnelsen angår legemiddelformer som kan oppnås ved ekstrudering og påfølgende formgivning av en løsemiddelfri smelte, og som i tillegg til ett eller flere virkestoffer inneholder A) 10 til 90 vekt% av en termoplastisk bearbeidbar, vannløselig polymer, B) 5 til 85 vekt% isomalt, og C) O til 5 vekt% lecitin, idet summen av alle innholdsstoffer skal være 100%.
NO981394A 1995-09-29 1998-03-27 Faste legemiddelformer som kan oppnås ved ekstrudering av en isomaltholdig polymersmelte som inneholder virkestoff NO981394D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19536394A DE19536394A1 (de) 1995-09-29 1995-09-29 Feste Arzneiformen, erhältlich durch Extrusion einer Isomalt enthaltenden Polymer-Wirkstoff-Schmelze
PCT/EP1996/004262 WO1997012603A1 (de) 1995-09-29 1996-09-30 Feste arzneiformen, erhältlich durch extrusion einer isomalt enthaltenden polymer-wirkstoff-schmelze

Publications (2)

Publication Number Publication Date
NO981394L true NO981394L (no) 1998-03-27
NO981394D0 NO981394D0 (no) 1998-03-27

Family

ID=7773633

Family Applications (1)

Application Number Title Priority Date Filing Date
NO981394A NO981394D0 (no) 1995-09-29 1998-03-27 Faste legemiddelformer som kan oppnås ved ekstrudering av en isomaltholdig polymersmelte som inneholder virkestoff

Country Status (22)

Country Link
US (1) US6187342B1 (no)
EP (1) EP0854707B1 (no)
JP (1) JP4041163B2 (no)
KR (1) KR19990063853A (no)
CN (1) CN1200694C (no)
AT (1) ATE228355T1 (no)
AU (1) AU7282896A (no)
BG (1) BG102346A (no)
BR (1) BR9610799A (no)
CA (1) CA2230950C (no)
CZ (1) CZ95998A3 (no)
DE (2) DE19536394A1 (no)
DK (1) DK0854707T3 (no)
ES (1) ES2187678T3 (no)
HU (1) HUP9903384A3 (no)
IL (1) IL123250A (no)
MX (1) MX9801988A (no)
NO (1) NO981394D0 (no)
RU (1) RU2197228C2 (no)
TW (1) TW438599B (no)
WO (1) WO1997012603A1 (no)
ZA (1) ZA968130B (no)

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DE19809242A1 (de) * 1998-03-05 1999-09-09 Basf Ag Verfahren zur Herstellung von festen, sphärischen Formkörpern, enthaltend pharmazeutische Wirkstoffe in einer Bindemittelmatrix
US6465009B1 (en) 1998-03-18 2002-10-15 Yamanouchi Pharmaceutical Co., Ltd. Water soluble polymer-based rapidly dissolving tablets and production processes thereof
DE60028754T2 (de) * 1999-11-12 2007-05-31 Abbott Laboratories, Abbott Park Feste dispersion mit ritonavir, fenofibrat oder griseofulvin
US7364752B1 (en) 1999-11-12 2008-04-29 Abbott Laboratories Solid dispersion pharamaceutical formulations
US20070141107A1 (en) * 2000-03-15 2007-06-21 Orbusneich Medical, Inc. Progenitor Endothelial Cell Capturing with a Drug Eluting Implantable Medical Device
US9522217B2 (en) 2000-03-15 2016-12-20 Orbusneich Medical, Inc. Medical device with coating for capturing genetically-altered cells and methods for using same
US8088060B2 (en) * 2000-03-15 2012-01-03 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
DE10026698A1 (de) * 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
KR20040100835A (ko) * 2001-02-15 2004-12-02 킹 파머슈티칼스 리서치 앤드 디벨로프먼트 아이엔씨 안정된 제약및 갑상선 내분비 호르몬 구성물 및 그제조방법
US20030224047A1 (en) * 2001-02-15 2003-12-04 Franz G. Andrew Levothyroxine compositions and methods
US6555581B1 (en) 2001-02-15 2003-04-29 Jones Pharma, Inc. Levothyroxine compositions and methods
US20030032675A1 (en) * 2001-02-15 2003-02-13 Franz G. Andrew Manufacture of thyroid hormone tablets having consistent active moiety amounts
AR033444A1 (es) * 2001-03-26 2003-12-17 Smithkline Beecham Corp Forma solida de dosificacion util para la administracion oral de un compuesto activo de nicotina, a traves de la mucosa y uso de un compuesto activo de nicotina para prepararla
FR2823974B1 (fr) * 2001-04-25 2004-10-15 Pf Medicament Pastille medicamenteuse a liberation lente du principe actif
US20030190349A1 (en) * 2001-08-10 2003-10-09 Franz G. Andrew Methods of stabilizing pharmaceutical compositions
US20030198671A1 (en) * 2001-08-10 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique plasma AUC properties
US20030180353A1 (en) * 2001-08-10 2003-09-25 Franz G. Andrew Stabilized pharmaceutical compositions
US20030198667A1 (en) * 2001-08-10 2003-10-23 Franz Andrew G. Methods of producing dispersible pharmaceutical compositions
US20030195253A1 (en) * 2001-08-14 2003-10-16 Franz G. Andrew Unadsorbed levothyroxine pharmaceutical compositions, methods of making and methods of administration
US20030199587A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique Cmax properties
US20030198672A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique triidothyronine plasma AUC properties
US7101569B2 (en) 2001-08-14 2006-09-05 Franz G Andrew Methods of administering levothyroxine pharmaceutical compositions
US20030199586A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Unique levothyroxine aqueous materials
US20030203967A1 (en) * 2001-08-14 2003-10-30 Franz G. Andrew Levothyroxine compositions having unique Tmax properties
US20030175337A1 (en) * 2001-10-29 2003-09-18 Franz G. Andrew Levothyroxine compositions having unique triiodothyronine Tmax properties
KR100514590B1 (ko) * 2001-12-18 2005-09-14 주식회사 대웅 프라바스타틴나트륨 및 안정화제로서의 코폴리비돈을함유하는 약제 조성물
US20040101543A1 (en) * 2002-03-22 2004-05-27 John Liu Nicotine-containing oral dosage form
US20080051411A1 (en) * 2002-12-17 2008-02-28 Cink Russell D Salts of Fenofibric Acid and Pharmaceutical Formulations Thereof
WO2004054568A1 (en) * 2002-12-17 2004-07-01 Abbott Gmbh & Co. Kg Formulation comprising fenofibric acid, a physiologically acceptable salt or derivative thereof
BRPI0407181A (pt) * 2003-02-03 2006-02-07 Novartis Ag Formulação farmacêutica
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
US8377952B2 (en) * 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
GB2418854B (en) * 2004-08-31 2009-12-23 Euro Celtique Sa Multiparticulates
RU2276985C1 (ru) * 2004-10-07 2006-05-27 Открытое акционерное общество "Щелковский витаминный завод" Фармацевтическая композиция для лечения заболеваний поджелудочной железы и расстройств пищеварения, связанных с заболеванием печени
US20080292702A1 (en) * 2005-12-16 2008-11-27 Hanmi Pharm. Co. Ltd. Solid Dispersion Comprising An Active Ingredient Having A Low Melting Point And Tablet For Oral Administration Comprising Same
EP2140861A1 (en) * 2008-06-30 2010-01-06 Abbott GmbH & Co. KG Pharmaceutical dosage form comprising polymeric carrier composition
CA2813510A1 (en) * 2010-10-14 2012-04-19 Abbott Gmbh & Co. Kg Curcuminoid solid dispersion formulation
MX358650B (es) 2011-03-21 2018-08-30 Boehringer Ingelheim Int Preparacion solida con contenido de ambroxol.
US9375033B2 (en) 2014-02-14 2016-06-28 R.J. Reynolds Tobacco Company Tobacco-containing gel composition
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SU1440327A3 (ru) * 1980-07-03 1988-11-23 Тейт Энд Лайл Паблик Лимитед Компани (Фирма) Способ получени таблетированной формы препарата
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DE3612211A1 (de) 1986-04-11 1987-10-15 Basf Ag Kontinuierliches verfahren zum tablettieren
DE3826946C1 (no) * 1988-08-09 1990-03-15 A. Nattermann & Cie Gmbh, 5000 Koeln, De
BR9508034A (pt) * 1994-06-14 1997-09-16 Fuisz Technologies Ltd Processo e aparelhagem para a preparação de uma unidade comestível que se dissolve rapidamente a referida unidade composição para liberar um ingrediente ativo processo para administração de um ingrediente ativo a um hospedeiro humano e produto provisório para fabricação da unidade comestível

Also Published As

Publication number Publication date
RU2197228C2 (ru) 2003-01-27
HUP9903384A3 (en) 2001-04-28
CN1198094A (zh) 1998-11-04
BG102346A (bg) 1998-10-30
JP4041163B2 (ja) 2008-01-30
ATE228355T1 (de) 2002-12-15
HUP9903384A2 (hu) 2000-10-28
IL123250A (en) 2000-08-31
US6187342B1 (en) 2001-02-13
JPH11512729A (ja) 1999-11-02
EP0854707B1 (de) 2002-11-27
MX9801988A (es) 1998-08-30
DK0854707T3 (da) 2002-12-16
ZA968130B (en) 1998-03-27
EP0854707A1 (de) 1998-07-29
BR9610799A (pt) 1999-07-13
IL123250A0 (en) 1998-09-24
DE19536394A1 (de) 1997-04-03
DE59609923D1 (de) 2003-01-09
CA2230950A1 (en) 1997-04-10
NO981394D0 (no) 1998-03-27
WO1997012603A1 (de) 1997-04-10
CN1200694C (zh) 2005-05-11
ES2187678T3 (es) 2003-06-16
CZ95998A3 (cs) 1998-08-12
TW438599B (en) 2001-06-07
KR19990063853A (ko) 1999-07-26
CA2230950C (en) 2007-12-04
AU7282896A (en) 1997-04-28

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