NO980422L - Endotelinreseptorantagonister - Google Patents

Endotelinreseptorantagonister

Info

Publication number: NO980422L
Authority: NO; Norway
Prior art keywords: endothelin
Prior art date: 1995-08-02

Application number

NO980422A

Other languages

English (en)

Norwegian (no)

Other versions

NO980422D0 (no

Inventor

Juan Ignacio Luengo

John Duncan Elliott

Original Assignee

Smithkline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-08-02

Filing date

1998-01-30

Publication date

1998-03-24

1998-01-30 Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp

1998-01-30 Publication of NO980422D0 publication Critical patent/NO980422D0/no

1998-03-24 Publication of NO980422L publication Critical patent/NO980422L/no

Links

102000002045 Endothelin Human genes 0.000 title 1
108050009340 Endothelin Proteins 0.000 title 1
ZUBDGKVDJUIMQQ-UBFCDGJISA-N endothelin-1 Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(O)=O)NC(=O)[C@H]1NC(=O)[C@H](CC=2C=CC=CC=2)NC(=O)[C@@H](CC=2C=CC(O)=CC=2)NC(=O)[C@H](C(C)C)NC(=O)[C@H]2CSSC[C@@H](C(N[C@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N2)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](N)CSSC1)C1=CNC=N1 ZUBDGKVDJUIMQQ-UBFCDGJISA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrrole Compounds (AREA)

NO980422A 1995-08-02 1998-01-30 Endotelinreseptorantagonister NO980422L (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US179295P	1995-08-02	1995-08-02
US1098296P	1996-02-01	1996-02-01
PCT/US1996/012581 WO1997004772A1 (en)	1995-08-02	1996-08-02	Endothelin receptor antagonists

Publications (2)

Publication Number	Publication Date
NO980422D0 NO980422D0 (no)	1998-01-30
NO980422L true NO980422L (no)	1998-03-24

Family

ID=26669471

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO980422A NO980422L (no)	1995-08-02	1998-01-30	Endotelinreseptorantagonister

Country Status (25)

Country	Link
US (5)	US5969151A (de)
EP (2)	EP0841925B1 (de)
JP (2)	JP2001517195A (de)
KR (1)	KR19990036032A (de)
CN (1)	CN1196680A (de)
AP (1)	AP9801182A0 (de)
AT (1)	ATE341324T1 (de)
AU (2)	AU717172B2 (de)
BG (1)	BG102229A (de)
BR (1)	BR9609914A (de)
CA (2)	CA2228293A1 (de)
CZ (1)	CZ30498A3 (de)
DE (2)	DE69619116T2 (de)
EA (1)	EA000952B1 (de)
ES (2)	ES2171697T3 (de)
HU (1)	HU220776B1 (de)
MX (1)	MX9800975A (de)
NO (1)	NO980422L (de)
NZ (1)	NZ315846A (de)
OA (1)	OA10755A (de)
PL (1)	PL184272B1 (de)
RO (1)	RO115802B1 (de)
SK (1)	SK282584B6 (de)
TR (1)	TR199800152T1 (de)
WO (2)	WO1997004772A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR017426A1 (es)	1997-12-08	2001-09-05	Smithkline Beecham Corp	Sal de monoargininilo del acido (e)-3-[1-n-butil-5-[2-(2-carboxifenil)metoxi-4-clorofenil]-1h-pirazol-4-il]-2-[(5-metoxi-2,3-dihidrobenzofuran-6-il)metil]-prop-2-enoico, composicion farmaceutica que la contiene, su uso para la manufactura de un medicamento y procedimiento para su preparacion
DE10155076A1 (de) *	2001-11-09	2003-05-22	Merck Patent Gmbh	Verwendung von Endothelin-Rezeptor-Antagonisten zur Behandlung von Tumorerkrankungen
WO2004002409A2 (en) *	2002-06-27	2004-01-08	Nitromed, Inc.	Cyclooxygenase-2 selective inhibitors, compositions and methods of use
WO2006075955A1 (en) *	2005-01-13	2006-07-20	Astrazeneca Ab	Pyrazolyl acylsulfonamide derivatives as endothelin converting enzyme inhibitors and useful in the treatment of chronic obstructive pulmonary disease
US7521435B2 (en) *	2005-02-18	2009-04-21	Pharma Diagnostics, N.V.	Silicon containing compounds having selective COX-2 inhibitory activity and methods of making and using the same
US8012038B1 (en)	2008-12-11	2011-09-06	Taylor Made Golf Company, Inc.	Golf club head
US10086240B1 (en)	2015-08-14	2018-10-02	Taylor Made Golf Company, Inc.	Golf club head
EP3380970B1 (de)	2015-11-24	2023-01-04	Sanford Burnham Prebys Medical Discovery Institute	Neuartige azolderivate als apelin-rezeptoragonisten
US10773135B1 (en)	2019-08-28	2020-09-15	Taylor Made Golf Company, Inc.	Golf club head

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1937241A1 (de) *	1968-08-02	1970-02-19	Sumitomo Chemical Co	3,5-Dioxopyrazolidinderivate und Verfahren zu ihrer Herstellung
JPH01211582A (ja) *	1988-02-16	1989-08-24	Tanabe Seiyaku Co Ltd	ベンゾジオキソール誘導体
EP0403158A3 (de) *	1989-06-14	1991-12-18	Smithkline Beecham Corporation	Imidazolyl-Alkensäuren
AU9137791A (en) *	1990-12-14	1992-07-08	Smithkline Beecham Corporation	Imidazolyl-alkenoic acids
FR2682379B1 (fr) *	1991-10-09	1994-02-11	Rhone Poulenc Agrochimie	Nouveaux phenylpyrazoles fongicides.
WO1994022830A1 (en) *	1993-03-31	1994-10-13	Smithkline Beecham Corporation	Chemical compounds
JP2847969B2 (ja) *	1993-08-18	1999-01-20	萬有製薬株式会社	エンドセリン拮抗活性を有する複素芳香環縮合シクロペンテン誘導体
IL111613A0 (en) *	1993-11-12	1995-01-24	Rhone Poulenc Rorer Ltd	Substituted phenyl compounds, their preparation and pharmaceutical compositions containing them
AU3416995A (en) *	1994-09-02	1996-03-27	Smithkline Beecham Corporation	Endothelin receptor antagonists

1996
- 1996-08-02 JP JP50788797A patent/JP2001517195A/ja not_active Ceased
- 1996-08-02 AT AT96928036T patent/ATE341324T1/de not_active IP Right Cessation
- 1996-08-02 WO PCT/US1996/012581 patent/WO1997004772A1/en not_active Ceased
- 1996-08-02 PL PL96324745A patent/PL184272B1/pl not_active IP Right Cessation
- 1996-08-02 ES ES96926243T patent/ES2171697T3/es not_active Expired - Lifetime
- 1996-08-02 AU AU67645/96A patent/AU717172B2/en not_active Ceased
- 1996-08-02 HU HU9902817A patent/HU220776B1/hu not_active IP Right Cessation
- 1996-08-02 AP APAP/P/1998/001182A patent/AP9801182A0/en unknown
- 1996-08-02 SK SK113-98A patent/SK282584B6/sk unknown
- 1996-08-02 CN CN96197111A patent/CN1196680A/zh active Pending
- 1996-08-02 KR KR1019980700697A patent/KR19990036032A/ko not_active Ceased
- 1996-08-02 EP EP96928036A patent/EP0841925B1/de not_active Expired - Lifetime
- 1996-08-02 EA EA199800185A patent/EA000952B1/ru not_active IP Right Cessation
- 1996-08-02 AU AU66463/96A patent/AU6646396A/en not_active Abandoned
- 1996-08-02 NZ NZ315846A patent/NZ315846A/xx unknown
- 1996-08-02 BR BR9609914A patent/BR9609914A/pt not_active Application Discontinuation
- 1996-08-02 WO PCT/US1996/012661 patent/WO1997004773A1/en not_active Ceased
- 1996-08-02 JP JP9507907A patent/JPH11511133A/ja not_active Ceased
- 1996-08-02 RO RO98-00135A patent/RO115802B1/ro unknown
- 1996-08-02 MX MX9800975A patent/MX9800975A/es not_active IP Right Cessation
- 1996-08-02 CZ CZ98304A patent/CZ30498A3/cs unknown
- 1996-08-02 DE DE69619116T patent/DE69619116T2/de not_active Expired - Fee Related
- 1996-08-02 CA CA002228293A patent/CA2228293A1/en not_active Abandoned
- 1996-08-02 TR TR1998/00152T patent/TR199800152T1/xx unknown
- 1996-08-02 CA CA002228296A patent/CA2228296A1/en not_active Abandoned
- 1996-08-02 DE DE69636597T patent/DE69636597T2/de not_active Expired - Fee Related
- 1996-08-02 ES ES96928036T patent/ES2273350T3/es not_active Expired - Lifetime
- 1996-08-02 EP EP96926243A patent/EP0843551B1/de not_active Expired - Lifetime
1998
- 1998-01-28 OA OA9800014A patent/OA10755A/en unknown
- 1998-01-30 NO NO980422A patent/NO980422L/no not_active Application Discontinuation
- 1998-02-02 BG BG102229A patent/BG102229A/xx unknown
- 1998-07-23 US US09/121,545 patent/US5969151A/en not_active Expired - Fee Related
1999
- 1999-01-08 US US09/227,361 patent/US5958968A/en not_active Expired - Fee Related
- 1999-06-29 US US09/342,989 patent/US6096897A/en not_active Expired - Fee Related
- 1999-12-14 US US09/460,487 patent/US6353116B1/en not_active Expired - Fee Related
2001
- 2001-11-30 US US10/021,461 patent/US6482956B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0841925B1 (de)	2006-10-04
US6096897A (en)	2000-08-01
ES2171697T3 (es)	2002-09-16
EP0843551A4 (de)	1998-08-12
US5969151A (en)	1999-10-19
DE69619116D1 (de)	2002-03-21
KR19990036032A (ko)	1999-05-25
WO1997004772A1 (en)	1997-02-13
EP0843551A1 (de)	1998-05-27
MX9800975A (es)	1998-04-30
ES2273350T3 (es)	2007-05-01
PL184272B1 (pl)	2002-09-30
EA000952B1 (ru)	2000-08-28
US6353116B1 (en)	2002-03-05
WO1997004773A1 (en)	1997-02-13
EA199800185A1 (ru)	1998-10-29
SK282584B6 (sk)	2002-10-08
ATE341324T1 (de)	2006-10-15
HUP9902817A3 (en)	2001-03-28
DE69636597T2 (de)	2007-08-16
CN1196680A (zh)	1998-10-21
US6482956B2 (en)	2002-11-19
SK11398A3 (en)	1998-07-08
DE69619116T2 (de)	2002-09-19
EP0841925A4 (de)	2001-10-17
RO115802B1 (ro)	2000-06-30
EP0843551B1 (de)	2002-02-06
AP9801182A0 (en)	1998-01-31
AU717172B2 (en)	2000-03-16
CZ30498A3 (cs)	1998-07-15
DE69636597D1 (de)	2006-11-16
BG102229A (en)	1998-09-30
BR9609914A (pt)	1999-07-06
NZ315846A (en)	1999-01-28
NO980422D0 (no)	1998-01-30
OA10755A (en)	2002-12-13
JPH11511133A (ja)	1999-09-28
US5958968A (en)	1999-09-28
JP2001517195A (ja)	2001-10-02
CA2228293A1 (en)	1997-02-13
TR199800152T1 (xx)	1998-05-21
HUP9902817A2 (hu)	1999-12-28
HU220776B1 (hu)	2002-05-28
CA2228296A1 (en)	1997-02-13
AU6764596A (en)	1997-02-26
AU6646396A (en)	1997-02-26
EP0841925A1 (de)	1998-05-20
PL324745A1 (en)	1998-06-08
US20020072614A1 (en)	2002-06-13

Publication	Publication Date	Title
NO961072L (no)	1996-09-19	Endotelinreseptorantagonister
ATA135896A (de)	2001-02-15	Skibob
DE69619116D1 (de)	2002-03-21	Endothelinrezeptorantagonisten
NO963131D0 (no)	1996-07-26	Endotelinreseptorantagonister
DE69626986D1 (de)	2003-04-30	Endothelinrezeptorantagonist
NO963213D0 (no)	1996-08-01	Endotelinreseptorantagonister
ATE198470T1 (de)	2001-01-15	Alkenyl-benzoylguanidine
DE69628924D1 (de)	2003-08-07	Endothelinrezeptorantagonisten
FI964165A0 (fi)	1996-10-17	Kopplingsklo foer skjutarm
ATE240972T1 (de)	2003-06-15	Cyclopeptolide
BR9501643A (pt)	1997-09-16	Helistato
BR9503866A (pt)	1997-10-14	Autolabor
FIU950271U0 (fi)	1995-05-24	Musunderlag
SE9501165D0 (sv)	1995-03-31	Hållaranordning
FI2161U1 (fi)	1995-10-31	Skyddshattsarrangemang
KR960030307U (ko)	1996-10-22	다시
FI964542A0 (fi)	1996-11-13	Gripharvester
BR9501962A (pt)	1997-08-26	Lotofone
FIU950165U0 (fi)	1995-03-30	Skyddsknapp foer moebler
FIU950097U0 (fi)	1995-02-17	Belysningsapparat
FIU950227U0 (fi)	1995-05-05	WC-pappersdispenser
KR970011857U (ko)	1997-04-25	밸트스타킹
FI952099A0 (fi)	1995-05-03	Takarbetsanordning
BR7500040U (pt)	1997-03-25	Raquet mastit
BR7502714U (pt)	1998-05-19	Impresscard

Legal Events

Date	Code	Title	Description
2005-10-17	FC2A	Withdrawal, rejection or dismissal of laid open patent application