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NO985335D0 - 2,4-Diaminopyrimidinderivater - Google Patents

2,4-Diaminopyrimidinderivater

Info

Publication number
NO985335D0
NO985335D0 NO985335A NO985335A NO985335D0 NO 985335 D0 NO985335 D0 NO 985335D0 NO 985335 A NO985335 A NO 985335A NO 985335 A NO985335 A NO 985335A NO 985335 D0 NO985335 D0 NO 985335D0
Authority
NO
Norway
Prior art keywords
diaminopyrimidine
Prior art date
Application number
NO985335A
Other languages
English (en)
Other versions
NO985335L (no
Inventor
Philippe Guerry
Henri Stalder
Pierre-Charles Wyss
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO985335D0 publication Critical patent/NO985335D0/no
Publication of NO985335L publication Critical patent/NO985335L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/06Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO985335A 1996-05-15 1998-11-16 2,4-Diaminopyrimidinderivater NO985335L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96107739 1996-05-15
PCT/EP1997/002355 WO1997043277A1 (en) 1996-05-15 1997-05-07 2,4-diaminopyrimidine derivatives

Publications (2)

Publication Number Publication Date
NO985335D0 true NO985335D0 (no) 1998-11-16
NO985335L NO985335L (no) 1999-01-15

Family

ID=8222784

Family Applications (1)

Application Number Title Priority Date Filing Date
NO985335A NO985335L (no) 1996-05-15 1998-11-16 2,4-Diaminopyrimidinderivater

Country Status (29)

Country Link
US (1) US5866583A (no)
EP (1) EP0901488B1 (no)
JP (1) JP3098259B2 (no)
KR (1) KR100295509B1 (no)
CN (1) CN1098260C (no)
AR (1) AR007088A1 (no)
AT (1) ATE227282T1 (no)
AU (1) AU726416B2 (no)
BR (1) BR9709251A (no)
CA (1) CA2254117C (no)
CO (1) CO4840509A1 (no)
CY (1) CY2425B1 (no)
CZ (1) CZ364698A3 (no)
DE (1) DE69716901T2 (no)
DK (1) DK0901488T3 (no)
ES (1) ES2184089T3 (no)
HR (1) HRP970260A2 (no)
IL (1) IL126702A0 (no)
MA (1) MA24182A1 (no)
NO (1) NO985335L (no)
NZ (1) NZ332481A (no)
PE (1) PE78898A1 (no)
PL (1) PL330277A1 (no)
PT (1) PT901488E (no)
TR (1) TR199802331T2 (no)
TW (1) TW438796B (no)
WO (1) WO1997043277A1 (no)
YU (1) YU51498A (no)
ZA (1) ZA973984B (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2281642C (en) * 1997-03-03 2008-02-05 F. Hoffmann-La Roche Ag Substituted 2,4-diaminopyrimidines
EP0966464B1 (en) * 1997-03-03 2003-05-28 Basilea Pharmaceutica AG Substituted 2,4-diaminopyrimidines
US6277860B1 (en) * 1999-10-29 2001-08-21 Pfizer Inc Furopyridine antibacterials
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
US6541014B2 (en) 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof
US20020068078A1 (en) 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
WO2005011677A1 (en) * 2003-06-13 2005-02-10 Arena Pharmaceuticals, Inc. 5-substituted 2h-pyrazole-3-carboxylic acid derivatives as agonists for the nicotinic acid receptor rup25 for the treatment of dyslipidemia and related diseases
WO2005016877A2 (en) * 2003-08-07 2005-02-24 Merck & Co., Inc. Pyrazole carboxamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1
WO2005016278A2 (en) 2003-08-12 2005-02-24 Advancis Pharmaceuticals Corporation Antibiotic product, use and formulation thereof
DE102005062987A1 (de) * 2005-12-28 2007-07-05 Grünenthal GmbH Substituierte Propiolsäureamide und ihre Verwendung zur Herstellung von Arzneimitteln
CA2695331A1 (en) * 2007-08-03 2009-02-12 F. Hoffmann-La Roche Ag Pyridinecarboxamide and benzamide derivatives as taar1 ligands
US8252790B2 (en) * 2008-11-21 2012-08-28 Raqualia Pharma Inc. Pyrazole-3-carboxamide derivative having 5-HT2B receptor antagonist activity
CA2750047A1 (en) * 2009-01-21 2010-07-29 Basilea Pharmaceutica Ag Novel bicyclic antibiotics
BR112012014683B1 (pt) * 2009-12-15 2017-11-07 Bayer Cropscience Ag Process for the production of 5-pyrazolcarboxylic acid derivatives 1-alkyl- / 1-aryl-substituted and compound acid
MA35024B1 (fr) 2011-04-05 2014-04-03 Pfizer Ltd Dérivés de pyrrolo-[2,3-d]pyrimidine servant d'inhibiteurs des kinases apparentés à la tropomyosine
DE102013208484B4 (de) 2013-05-08 2018-04-26 Wirtgen Gmbh Vorrichtung zum Bearbeiten von Straßen- oder Bodenoberflächen, sowie Verfahren zum Lenken einer Straßenfräsmaschine
WO2020041556A1 (en) * 2018-08-22 2020-02-27 The Regents Of The University Of Colorado, A Body Corporate N-substituted-1h-1,2,4-triazole-3-carboxamides, analogues thereof, and methods of treatment using same
AR117169A1 (es) * 2018-11-28 2021-07-14 Bayer Ag (tio)amidas de piridazina como compuestos fungicidas
EP4153566A1 (en) * 2020-05-19 2023-03-29 Bayer CropScience Aktiengesellschaft Azabicyclic(thio)amides as fungicidal compounds

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3485840A (en) * 1964-11-12 1969-12-23 Hoffmann La Roche 2,4-diamino - 5 - (2',4',5'-substituted benzyl) pyrimidines,intermediates and processes
US4515948A (en) * 1973-09-12 1985-05-07 Hoffmann-La Roche Inc. 2,4-Diamino-5-(4-amino and 4-dimethylamino-3,5-dimethoxy benzyl)pyrimidines
US4013644A (en) * 1976-03-15 1977-03-22 G. D. Searle & Co. [8 α(E), 13aβ]-5,8,13,13a-tetrahydro-2,3,10,11-tetramethoxy-8-(2-phenylethenyl)-6H-dibenzo[a,g]quinolizines and intermediates thereto
US4444770A (en) * 1980-05-29 1984-04-24 Bayer Aktiengesellschaft New imidazoazole-alkenoic acid amide compounds, intermediate products for their production, their production, and their medicinal use
US4594199A (en) * 1983-09-19 1986-06-10 E. R. Squibb & Sons, Inc. Method for making phosphinic acid intermediates
JPH07509215A (ja) * 1990-11-14 1995-10-12 カイロン コーポレイション ジヒドロ葉酸還元酵素の特異的阻害およびそのための化合物
JP3117721B2 (ja) * 1994-11-24 2000-12-18 エフ・ホフマン−ラ ロシュ アーゲー 新規なベンジルピリミジン類
WO1996040640A1 (en) * 1995-06-07 1996-12-19 Pfizer Inc. BIPHENYL-2-CARBOXYLIC ACID-TETRAHYDRO-ISOQUINOLIN-6-YL AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND/OR APOLIPOPROTEIN B (Apo B) SECRETION
DK0866791T3 (da) * 1995-12-04 2002-04-22 Arpida Ag Diaminopyrimidiner, farmaceutiske præparater indeholdende disse og deres anvendelse som antibakterielle midler

Also Published As

Publication number Publication date
CN1218465A (zh) 1999-06-02
ATE227282T1 (de) 2002-11-15
CO4840509A1 (es) 1999-09-27
CY2425B1 (en) 2004-11-12
PT901488E (pt) 2003-03-31
YU51498A (en) 1999-11-22
DE69716901D1 (de) 2002-12-12
BR9709251A (pt) 1999-08-10
IL126702A0 (en) 1999-08-17
HRP970260A2 (en) 1998-04-30
CZ364698A3 (cs) 1999-02-17
MA24182A1 (fr) 1997-12-31
TR199802331T2 (xx) 1999-04-21
CA2254117A1 (en) 1997-11-20
WO1997043277A1 (en) 1997-11-20
EP0901488A1 (en) 1999-03-17
PE78898A1 (es) 1998-11-13
JPH11511749A (ja) 1999-10-12
TW438796B (en) 2001-06-07
DK0901488T3 (da) 2003-03-03
DE69716901T2 (de) 2003-09-18
KR100295509B1 (ko) 2001-09-17
AR007088A1 (es) 1999-10-13
EP0901488B1 (en) 2002-11-06
AU726416B2 (en) 2000-11-09
JP3098259B2 (ja) 2000-10-16
CA2254117C (en) 2003-03-11
ZA973984B (en) 1997-11-17
US5866583A (en) 1999-02-02
ES2184089T3 (es) 2003-04-01
CN1098260C (zh) 2003-01-08
PL330277A1 (en) 1999-05-10
KR20000011053A (ko) 2000-02-25
AU2894297A (en) 1997-12-05
NO985335L (no) 1999-01-15
NZ332481A (en) 2000-04-28

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Legal Events

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