[go: up one dir, main page]

NO984920D0 - Sammensetninger omfattende en nitroneforbindelse for anvendelse ved behandling av okulµr inflammasjon - Google Patents

Sammensetninger omfattende en nitroneforbindelse for anvendelse ved behandling av okulµr inflammasjon

Info

Publication number
NO984920D0
NO984920D0 NO984920A NO984920A NO984920D0 NO 984920 D0 NO984920 D0 NO 984920D0 NO 984920 A NO984920 A NO 984920A NO 984920 A NO984920 A NO 984920A NO 984920 D0 NO984920 D0 NO 984920D0
Authority
NO
Norway
Prior art keywords
compositions
treatment
ocular inflammation
nitron compound
compound
Prior art date
Application number
NO984920A
Other languages
English (en)
Other versions
NO984920L (no
Inventor
Kenneth W Narducy
Efraim Duzman
John Michael Carney
Allan Lee Wilcox
Original Assignee
Centaur Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centaur Pharmaceuticals Inc filed Critical Centaur Pharmaceuticals Inc
Publication of NO984920D0 publication Critical patent/NO984920D0/no
Publication of NO984920L publication Critical patent/NO984920L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C291/00—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00
    • C07C291/02—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00 containing nitrogen-oxide bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/24—Oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Pyridine Compounds (AREA)
NO984920A 1996-04-23 1998-10-22 Preparater omfattende en nitronforbindelse for anvendelse ved behandling av okulµr inflammasjon NO984920L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1627696P 1996-04-23 1996-04-23
PCT/US1997/006604 WO1997039751A1 (en) 1996-04-23 1997-04-23 Compositions comprising a nitrone compound for use in treating ocular inflammation

Publications (2)

Publication Number Publication Date
NO984920D0 true NO984920D0 (no) 1998-10-22
NO984920L NO984920L (no) 1998-12-23

Family

ID=21776304

Family Applications (1)

Application Number Title Priority Date Filing Date
NO984920A NO984920L (no) 1996-04-23 1998-10-22 Preparater omfattende en nitronforbindelse for anvendelse ved behandling av okulµr inflammasjon

Country Status (13)

Country Link
US (2) US5972977A (no)
EP (1) EP0910370B1 (no)
JP (1) JP2000509375A (no)
CN (1) CN1219130A (no)
AT (1) ATE263559T1 (no)
AU (1) AU721531B2 (no)
CA (1) CA2252494A1 (no)
DE (1) DE69728536T2 (no)
IL (1) IL126725A0 (no)
NO (1) NO984920L (no)
NZ (1) NZ332561A (no)
TW (1) TW450952B (no)
WO (1) WO1997039751A1 (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050107366A1 (en) * 1991-06-18 2005-05-19 Carney John M. Spin trapping pharmaceutical compositions and methods for use thereof
CA2323490A1 (en) * 1998-03-13 1999-09-16 Lowell D. Waterbury Inhibition of angiogenesis
WO1999059576A1 (en) * 1998-05-19 1999-11-25 Centaur Pharmaceuticals, Inc. Aryl nitrone therapeutics for the treatment of inflammatory bowel disease
US6083989A (en) * 1999-05-18 2000-07-04 Centaur Pharmaceuticals, Inc. Aryl nitrone therapeutics for the treatment of inflammatory bowel disease
CA2332398A1 (en) 1998-05-19 1999-11-25 Ian Irwin Benzamide therapeutics for the treatment of inflammatory bowel disease
WO2000003977A1 (en) * 1998-07-17 2000-01-27 Centaur Pharmaceuticals, Inc. Alpha-(2-hydroxyphenyl) nitrone compounds, pharmaceutical compositions containing the same and their use for treating inflammation
US6730700B2 (en) * 1998-12-02 2004-05-04 Renovis, Inc. 3,4,5,-trisubstituted aryl nitrone compounds and pharmaceutical compositions containing the same
UA66401C2 (en) * 1998-12-02 2004-05-17 Sentor Pharmaceuticals Inc 3,4,5-trisubstituted aryl nitrone compounds and pharmaceutical composition containing the same
AU5601300A (en) * 1999-06-09 2000-12-28 Department Of The Army, U.S. Government Method and compositions for treating and preventing retinal damage
FR2846968B1 (fr) * 2002-11-08 2005-02-04 Salles Jean Pierre Nouveaux derives amphiphiles de l'alpha-c-phenyl-n-tert- butyl nitrone
US20050059638A1 (en) * 2003-08-04 2005-03-17 Kelly Michael G. Aryl, heteroaromatic and bicyclic aryl nitrone compounds, prodrugs and pharmaceutical compositions of the same to treat human disorders
US20050182060A1 (en) * 2004-02-13 2005-08-18 Kelly Michael G. 2-Substituted and 4-substituted aryl nitrone compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4153722A (en) * 1977-10-06 1979-05-08 William H. Rorer, Inc. Method of treatment
DK0496796T3 (da) * 1989-10-17 1994-10-03 Oklahoma Med Res Found Fremgangsmåde og præparater til inhibering af sygdomme i forbindelse med oxidativ beskadigelse
US5025032A (en) * 1989-10-17 1991-06-18 Oklahoma Medical Research Foundation Phenyl butyl nitrone compositions and methods for treatment of oxidative tissue damage
US5036097A (en) * 1989-10-17 1991-07-30 Oklahoma Medical Research Foundation Phenylbutyl nitrone compositions and methods for prevention of gastric ulceration
CA2111836C (en) * 1991-06-18 2006-08-29 John M. Carney Spin-trapping pharmaceutical compositions and methods for use thereof
US5455272A (en) * 1993-10-22 1995-10-03 Oklahoma Medical Research Foundation Spin trap nitronyl hindered phenols

Also Published As

Publication number Publication date
AU2736697A (en) 1997-11-12
AU721531B2 (en) 2000-07-06
JP2000509375A (ja) 2000-07-25
US6140356A (en) 2000-10-31
ATE263559T1 (de) 2004-04-15
DE69728536D1 (de) 2004-05-13
EP0910370B1 (en) 2004-04-07
TW450952B (en) 2001-08-21
WO1997039751A1 (en) 1997-10-30
CN1219130A (zh) 1999-06-09
NZ332561A (en) 2001-01-26
EP0910370A1 (en) 1999-04-28
IL126725A0 (en) 1999-08-17
CA2252494A1 (en) 1997-10-30
NO984920L (no) 1998-12-23
DE69728536T2 (de) 2005-02-24
US5972977A (en) 1999-10-26

Similar Documents

Publication Publication Date Title
NO973516D0 (no) Behandling av urininkontinens ved anvendelse av (S)-oksybutenin og (S)-desetyloksybutenin
CA2264901A1 (fr) Association inhibiteurs de no synthase et piegeurs des formes reactives de l'oxygene
WO1999013862A3 (en) A pharmaceutical composition for treating dysmenorrhea and premature labor
CA2223514A1 (en) Film-forming compositions of antihyperalgesic opiates and method of treating hyperalgesic conditions therewith
MX9702380A (es) Nuevas carboxamidas con actividad antifungica.
ATE202706T1 (de) Verwendung von 9-deoxyprostaglandinderivaten zur behandlung von glaukom
DE69429524D1 (de) Aminocyclohexylester und ihre anwendung
NO984920D0 (no) Sammensetninger omfattende en nitroneforbindelse for anvendelse ved behandling av okulµr inflammasjon
MY119375A (en) Treatment of tinnitus using neuroprotective agents
MX9710252A (es) Utilizacion de al menos un peptido en una composicion cosmetica o para la preparacion de un medicamento.
WO2000018316A3 (en) Sustained release, and comfortable ophthalmic composition and method for ocular therapy
TW324662B (en) Benzamide-containing pharmaceutical composition
AU2162700A (en) Supramolecular complexes containing therapeutic agents
DE60040616D1 (de) Verfahren zur behandlung maligner zellen eines patienten und pharmazeutische zusammensetzung zu dessen anwendung
CA2198580A1 (en) Combination therapy to treat osteoporosis
IL141515A0 (en) Optically active pyridyl-4h-1,2,4-oxadiazine derivative and its use in the treatment of vascular diseases
BR9508021A (pt) Composição farmacêutica para o tratamento de distúrbios esquizofrênicos, uso de um agente imunossupressor, e, processo de tratamento de um paciente esquizofrênico
TR199801184T2 (xx) Analjezik tesirli yeni bile�ikler.
US5798392C1 (en) Sulfonyl fluorides for the treatment of alzheimer's disease
CA2192965A1 (en) Anandamide analogue compositions and method of treating intraocular hypertension using same
GEP20032975B (en) Echinocandin Derivatives, Preparation Method and Pharmaceutical Composition
MX9701606A (es) Terapia de combinacion para evitar la perdida osea-progesterona y agonistas de estrogeno.
NZ328198A (en) a pharmaceutical composition containing hydroxyzine and a serotonin uptake inhibitor
WO1996021670A3 (en) Antifungal fusacandins
MX9604692A (es) Derivados de quinoxalina para el tratamiento de tinnitus.

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application