NO984740D0 - Isatinderivater som acetylcholinesteraseinhibitorer og analgetiske midler - Google Patents
Isatinderivater som acetylcholinesteraseinhibitorer og analgetiske midlerInfo
- Publication number
- NO984740D0 NO984740D0 NO984740A NO984740A NO984740D0 NO 984740 D0 NO984740 D0 NO 984740D0 NO 984740 A NO984740 A NO 984740A NO 984740 A NO984740 A NO 984740A NO 984740 D0 NO984740 D0 NO 984740D0
- Authority
- NO
- Norway
- Prior art keywords
- analgesics
- acetylcholinesterase inhibitors
- isatin derivatives
- isatin
- derivatives
- Prior art date
Links
- 229940035676 analgesics Drugs 0.000 title 1
- 239000000730 antalgic agent Substances 0.000 title 1
- 239000000544 cholinesterase inhibitor Substances 0.000 title 1
- JXDYKVIHCLTXOP-UHFFFAOYSA-N isatin Chemical class C1=CC=C2C(=O)C(=O)NC2=C1 JXDYKVIHCLTXOP-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63187096A | 1996-04-12 | 1996-04-12 | |
| PCT/US1997/003598 WO1997038993A1 (en) | 1996-04-12 | 1997-03-07 | Isatin derivatives as acetylcholinesterase inhibitors and analgesics |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO984740L NO984740L (no) | 1998-10-09 |
| NO984740D0 true NO984740D0 (no) | 1998-10-09 |
Family
ID=24533114
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO984740A NO984740D0 (no) | 1996-04-12 | 1998-10-09 | Isatinderivater som acetylcholinesteraseinhibitorer og analgetiske midler |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0892796B1 (no) |
| JP (1) | JP4109718B2 (no) |
| KR (1) | KR20000005379A (no) |
| CN (1) | CN1215399A (no) |
| AR (1) | AR006606A1 (no) |
| AT (1) | ATE207483T1 (no) |
| BR (1) | BR9708655A (no) |
| CA (1) | CA2252039C (no) |
| DE (1) | DE69707659T2 (no) |
| DK (1) | DK0892796T3 (no) |
| ES (1) | ES2165586T3 (no) |
| GR (1) | GR3037006T3 (no) |
| HU (1) | HUP9903473A3 (no) |
| IL (1) | IL126308A0 (no) |
| NO (1) | NO984740D0 (no) |
| PT (1) | PT892796E (no) |
| TW (1) | TW426678B (no) |
| WO (1) | WO1997038993A1 (no) |
| ZA (1) | ZA972990B (no) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6218383B1 (en) | 1998-08-07 | 2001-04-17 | Targacept, Inc. | Pharmaceutical compositions for the prevention and treatment of central nervous system disorders |
| JP5379692B2 (ja) | 2006-11-09 | 2013-12-25 | プロビオドルグ エージー | 潰瘍、癌及び他の疾患の治療のためのグルタミニルシクラーゼの阻害薬としての３−ヒドロキシ−１，５−ジヒドロ−ピロール−２−オン誘導体 |
| US9126987B2 (en) | 2006-11-30 | 2015-09-08 | Probiodrug Ag | Inhibitors of glutaminyl cyclase |
| AU2008220785B2 (en) | 2007-03-01 | 2013-02-21 | Vivoryon Therapeutics N.V. | New use of glutaminyl cyclase inhibitors |
| JP5667440B2 (ja) | 2007-04-18 | 2015-02-12 | プロビオドルグ エージー | グルタミニルシクラーゼ阻害剤としてのチオ尿素誘導体 |
| NZ598685A (en) | 2009-09-11 | 2013-05-31 | Probiodrug Ag | Heterocylcic derivatives as inhibitors of glutaminyl cyclase |
| CN102905532A (zh) | 2010-02-09 | 2013-01-30 | 约翰斯.霍普金斯大学 | 用于改善认知功能的方法和组合物 |
| CA2788656A1 (en) | 2010-02-16 | 2011-08-25 | Pfizer Inc. | (r)-4-((4-((4-(tetrahydrofuran-3-yloxy)benzo[d]isoxazol-3-yloxy)methyl)piperidin-1-yl)methyl)tetrahydro-2h-pyran-4-ol, a partial agonist of 5-ht4 receptors |
| JP6026284B2 (ja) | 2010-03-03 | 2016-11-16 | プロビオドルグ エージー | グルタミニルシクラーゼの阻害剤 |
| DK2545047T3 (da) | 2010-03-10 | 2014-07-28 | Probiodrug Ag | Heterocycliske inhibitorer af glutaminylcyclase (QC, EC 2.3.2.5) |
| EP2560953B1 (en) | 2010-04-21 | 2016-01-06 | Probiodrug AG | Inhibitors of glutaminyl cyclase |
| US8530670B2 (en) | 2011-03-16 | 2013-09-10 | Probiodrug Ag | Inhibitors |
| HK1215170A1 (zh) | 2012-11-14 | 2016-08-19 | The Johns Hopkins University | 治療精神分裂症的方法和組合物 |
| CA2893468C (en) | 2012-12-13 | 2021-01-12 | H. Lundbeck A/S | Use of vortioxetine and donepezil in the treatment of cognitive impairment |
| CA2904767C (en) | 2013-03-15 | 2022-06-21 | Agenebio, Inc. | Methods and compositions for improving cognitive function |
| WO2014144663A1 (en) | 2013-03-15 | 2014-09-18 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| US10537552B2 (en) | 2015-05-05 | 2020-01-21 | Carafe Drug Innovation, Llc | Substituted 5-hydroxyoxindoles and their use as analgesics and fever reducers |
| EA034167B8 (ru) | 2015-05-22 | 2021-04-27 | Эйджинбайо, Инк. | Фармацевтические композиции леветирацетама пролонгированного высвобождения |
| EP3461819B1 (en) | 2017-09-29 | 2020-05-27 | Probiodrug AG | Inhibitors of glutaminyl cyclase |
| CA3237487A1 (en) * | 2021-11-05 | 2023-05-11 | The Regents Of The University Of California | Alpha-2a adrenergic receptor modulators and uses thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5296488A (en) * | 1989-08-02 | 1994-03-22 | Hoechst-Roussel Pharmaceuticals Inc. | Method of using 2,3-dihydro-1-(pyridinylamino)-indoles as anticonvulsants and for the enhancement of memory |
| US5006537A (en) * | 1989-08-02 | 1991-04-09 | Hoechst-Roussel Pharmaceuticals, Inc. | 1,3-dihydro-1-(pyridinylamino)-2H-indol-2-ones |
| US4994472A (en) * | 1989-08-02 | 1991-02-19 | Hoechst-Roussel Pharmaceuticals Incorporated | 1-(pyridinylamino)-2-pyrrolidinones as pain relievers |
-
1997
- 1997-03-07 AT AT97908942T patent/ATE207483T1/de not_active IP Right Cessation
- 1997-03-07 DK DK97908942T patent/DK0892796T3/da active
- 1997-03-07 IL IL12630897A patent/IL126308A0/xx unknown
- 1997-03-07 ES ES97908942T patent/ES2165586T3/es not_active Expired - Lifetime
- 1997-03-07 CA CA002252039A patent/CA2252039C/en not_active Expired - Fee Related
- 1997-03-07 DE DE69707659T patent/DE69707659T2/de not_active Expired - Fee Related
- 1997-03-07 PT PT97908942T patent/PT892796E/pt unknown
- 1997-03-07 WO PCT/US1997/003598 patent/WO1997038993A1/en not_active Ceased
- 1997-03-07 CN CN97193728A patent/CN1215399A/zh active Pending
- 1997-03-07 EP EP97908942A patent/EP0892796B1/en not_active Expired - Lifetime
- 1997-03-07 JP JP53708497A patent/JP4109718B2/ja not_active Expired - Fee Related
- 1997-03-07 HU HU9903473A patent/HUP9903473A3/hu unknown
- 1997-03-07 BR BR9708655A patent/BR9708655A/pt not_active Application Discontinuation
- 1997-04-07 TW TW086104363A patent/TW426678B/zh active
- 1997-04-08 ZA ZA9702990A patent/ZA972990B/xx unknown
- 1997-04-11 AR ARP970101447A patent/AR006606A1/es unknown
-
1998
- 1998-10-09 NO NO984740A patent/NO984740D0/no unknown
- 1998-10-12 KR KR1019980708105A patent/KR20000005379A/ko not_active Abandoned
-
2001
- 2001-10-25 GR GR20010401584T patent/GR3037006T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2072597A (en) | 1997-11-07 |
| TW426678B (en) | 2001-03-21 |
| CN1215399A (zh) | 1999-04-28 |
| BR9708655A (pt) | 1999-08-03 |
| EP0892796A1 (en) | 1999-01-27 |
| DE69707659D1 (de) | 2001-11-29 |
| WO1997038993A1 (en) | 1997-10-23 |
| NO984740L (no) | 1998-10-09 |
| DE69707659T2 (de) | 2002-05-08 |
| ATE207483T1 (de) | 2001-11-15 |
| JP2001508400A (ja) | 2001-06-26 |
| EP0892796B1 (en) | 2001-10-24 |
| ZA972990B (en) | 1997-11-03 |
| AU716997B2 (en) | 2000-03-16 |
| IL126308A0 (en) | 1999-05-09 |
| ES2165586T3 (es) | 2002-03-16 |
| JP4109718B2 (ja) | 2008-07-02 |
| PT892796E (pt) | 2002-03-28 |
| AR006606A1 (es) | 1999-09-08 |
| CA2252039C (en) | 2002-12-24 |
| HUP9903473A2 (hu) | 2000-05-28 |
| CA2252039A1 (en) | 1997-10-23 |
| DK0892796T3 (da) | 2001-11-19 |
| HUP9903473A3 (en) | 2000-09-28 |
| KR20000005379A (en) | 2000-01-25 |
| GR3037006T3 (en) | 2002-01-31 |
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