NO973342L - Anvendelse av 3,4-difenylkromaner til fremstilling av et farmasöytisk preparat for behandling eller profylakse av cerebrale degenerative sykdommer - Google Patents
Anvendelse av 3,4-difenylkromaner til fremstilling av et farmasöytisk preparat for behandling eller profylakse av cerebrale degenerative sykdommerInfo
- Publication number
- NO973342L NO973342L NO973342A NO973342A NO973342L NO 973342 L NO973342 L NO 973342L NO 973342 A NO973342 A NO 973342A NO 973342 A NO973342 A NO 973342A NO 973342 L NO973342 L NO 973342L
- Authority
- NO
- Norway
- Prior art keywords
- prophylaxis
- preparation
- treatment
- pharmaceutical composition
- diphenylchromanes
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 238000011321 prophylaxis Methods 0.000 title abstract 2
- 238000011282 treatment Methods 0.000 title abstract 2
- FNIBSWRSKVEZDZ-UHFFFAOYSA-N 3,4-diphenyl-3,4-dihydro-2h-chromene Chemical class C1OC2=CC=CC=C2C(C=2C=CC=CC=2)C1C1=CC=CC=C1 FNIBSWRSKVEZDZ-UHFFFAOYSA-N 0.000 title 1
- 230000002490 cerebral effect Effects 0.000 title 1
- 208000015122 neurodegenerative disease Diseases 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 210000004556 brain Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000003412 degenerative effect Effects 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001302 tertiary amino group Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
Abstract
Foreliggende oppfinnelse til- veiebringer nye anvendelser av forbin- delser med den generelle formel (I) (I) hvor R\ r* og R^ hver for seg er hydro- gen, hydroksy, halogen, trifluormetyl, lavere alkyl, lavere alkoksy eller (tertiært amino)(lavere alkoksy), og R^ og R-" hver for seg er hydrogen eller lavere alkyl, eller som et farmasøytisk akseptabelt salt derav, i kombinasjon med en farmasøytisk akseptabel bærer til fremstilling av et farmasøytisk preparat for behandling eller profyl- akse av hjernedegenerative forstyrrel- ser.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK6895 | 1995-01-20 | ||
| DK77695 | 1995-06-30 | ||
| PCT/DK1996/000010 WO1996022091A1 (en) | 1995-01-20 | 1996-01-10 | Use of 3,4-diphenyl chromans for the manufacture of a pharmaceutical composition for the treatment or prophylaxis of cerebral degenerative disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO973342D0 NO973342D0 (no) | 1997-07-18 |
| NO973342L true NO973342L (no) | 1997-07-18 |
Family
ID=26063233
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO973342A NO973342L (no) | 1995-01-20 | 1997-07-18 | Anvendelse av 3,4-difenylkromaner til fremstilling av et farmasöytisk preparat for behandling eller profylakse av cerebrale degenerative sykdommer |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US5696149A (no) |
| EP (1) | EP0809495A1 (no) |
| JP (1) | JPH10512269A (no) |
| KR (1) | KR19980701549A (no) |
| CN (1) | CN1168101A (no) |
| AU (1) | AU4328896A (no) |
| BR (1) | BR9606766A (no) |
| CA (1) | CA2208856A1 (no) |
| CZ (1) | CZ212097A3 (no) |
| HU (1) | HUP9702246A3 (no) |
| IL (1) | IL116828A (no) |
| NO (1) | NO973342L (no) |
| WO (1) | WO1996022091A1 (no) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2233888A1 (en) | 1995-10-06 | 1997-04-10 | Ligand Pharmaceuticals Incorporated | Dimer-selective rxr modulators and methods for their use |
| US5756539A (en) * | 1996-07-11 | 1998-05-26 | Novo Nordis A/S | 3, 4-diphenyl chromans for inhibiting one or more psychiatric disorders |
| US5958967A (en) * | 1996-10-28 | 1999-09-28 | Novo Nordisk A/S | Cis-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes |
| WO1998032437A1 (en) * | 1997-01-29 | 1998-07-30 | Novo Nordisk A/S | Use of 3,4-diphenyl chromans for the manufacture of a pharmaceutical composition for inhibiting one or more psychiatric disorders |
| US8080675B2 (en) | 2004-09-21 | 2011-12-20 | Marshall Edwards, Inc. | Chroman derivatives, medicaments and use in therapy |
| EP1794141B1 (en) | 2004-09-21 | 2011-11-09 | Marshall Edwards, Inc. | Substituted chroman derivatives, medicaments and use in therapy |
| EP2120925A4 (en) * | 2007-03-16 | 2010-04-07 | Novogen Res Pty Ltd | METHOD FOR INTRODUCING AUTOPHAGIA |
| KR20110101135A (ko) * | 2008-10-22 | 2011-09-15 | 노보겐 리서치 피티와이 리미티드 | 예정 세포 사멸을 유도하는 방법 |
| US9708283B2 (en) | 2010-11-01 | 2017-07-18 | Mei Pharma, Inc. | Isoflavonoid compositions and methods for the treatment of cancer |
| SI2953938T1 (en) | 2014-02-07 | 2018-01-31 | Novogen Ltd. | Functionalized benzopyran compounds and their use |
| CN116139125A (zh) | 2015-02-02 | 2023-05-23 | 梅制药公司 | 联合治疗 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3822287A (en) * | 1969-04-17 | 1974-07-02 | Rexall Drug Chemical | Process for preparation of substituted 3,4-(diphenyl)chromans |
| US4447622A (en) * | 1981-09-22 | 1984-05-08 | Council Of Scientific And Industrial Research Rafi Marg | Preparation of l- and d-isomers of dl-3,4-trans-2,2-disubstituted-3,4-diarylchromans and derivatives thereof |
| US5280040A (en) * | 1993-03-11 | 1994-01-18 | Zymogenetics, Inc. | Methods for reducing bone loss using centchroman derivatives |
| US5451603A (en) * | 1993-03-11 | 1995-09-19 | Zymogenetics, Inc. | 3,4-diarylchromans for treatment of dermatitis |
| DE4311870C2 (de) * | 1993-04-10 | 1998-07-30 | Altramed Holdings Ltd | Verwendung eines Anti-Östrigens zur Therapie und Prophylaxe von Demenz-Erkrankungen |
| DE4320896A1 (de) * | 1993-06-24 | 1995-01-05 | Denecke Rainer Dr Med Vet | Präparat zur Therapie und Prophylaxe von Demenz-Erkrankungen |
| US5554601A (en) * | 1993-11-05 | 1996-09-10 | University Of Florida | Methods for neuroprotection |
-
1996
- 1996-01-10 AU AU43288/96A patent/AU4328896A/en not_active Abandoned
- 1996-01-10 BR BR9606766A patent/BR9606766A/pt not_active Application Discontinuation
- 1996-01-10 CN CN96191516A patent/CN1168101A/zh active Pending
- 1996-01-10 CA CA002208856A patent/CA2208856A1/en not_active Abandoned
- 1996-01-10 JP JP8521976A patent/JPH10512269A/ja active Pending
- 1996-01-10 KR KR1019970704940A patent/KR19980701549A/ko not_active Withdrawn
- 1996-01-10 EP EP96900091A patent/EP0809495A1/en not_active Withdrawn
- 1996-01-10 HU HU9702246A patent/HUP9702246A3/hu unknown
- 1996-01-10 WO PCT/DK1996/000010 patent/WO1996022091A1/en not_active Ceased
- 1996-01-10 CZ CZ972120A patent/CZ212097A3/cs unknown
- 1996-01-11 US US08/585,012 patent/US5696149A/en not_active Expired - Fee Related
- 1996-01-19 IL IL11682896A patent/IL116828A/xx active IP Right Grant
-
1997
- 1997-01-10 US US08/783,420 patent/US5827873A/en not_active Expired - Fee Related
- 1997-07-18 NO NO973342A patent/NO973342L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US5827873A (en) | 1998-10-27 |
| CZ212097A3 (en) | 1997-11-12 |
| WO1996022091A1 (en) | 1996-07-25 |
| IL116828A0 (en) | 1996-05-14 |
| EP0809495A1 (en) | 1997-12-03 |
| HUP9702246A2 (hu) | 1998-12-28 |
| NO973342D0 (no) | 1997-07-18 |
| MX9705390A (es) | 1997-10-31 |
| US5696149A (en) | 1997-12-09 |
| JPH10512269A (ja) | 1998-11-24 |
| IL116828A (en) | 1999-11-30 |
| CN1168101A (zh) | 1997-12-17 |
| HUP9702246A3 (en) | 1999-12-28 |
| CA2208856A1 (en) | 1996-07-25 |
| KR19980701549A (ko) | 1998-05-15 |
| AU4328896A (en) | 1996-08-07 |
| BR9606766A (pt) | 1997-12-30 |
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