NO973242L - Anvendelse av 3,4-difenylkromaner til fremstilling av et farmasöytisk preparat for behandling eller profylakse av idiopatisk eller fysiologisk gynekomasti - Google Patents
Anvendelse av 3,4-difenylkromaner til fremstilling av et farmasöytisk preparat for behandling eller profylakse av idiopatisk eller fysiologisk gynekomastiInfo
- Publication number
- NO973242L NO973242L NO973242A NO973242A NO973242L NO 973242 L NO973242 L NO 973242L NO 973242 A NO973242 A NO 973242A NO 973242 A NO973242 A NO 973242A NO 973242 L NO973242 L NO 973242L
- Authority
- NO
- Norway
- Prior art keywords
- gynecomastia
- prophylaxis
- physiological
- preparation
- treatment
- Prior art date
Links
- 201000000079 gynecomastia Diseases 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 238000011321 prophylaxis Methods 0.000 title abstract 2
- 238000011282 treatment Methods 0.000 title abstract 2
- FNIBSWRSKVEZDZ-UHFFFAOYSA-N 3,4-diphenyl-3,4-dihydro-2h-chromene Chemical class C1OC2=CC=CC=C2C(C=2C=CC=CC=2)C1C1=CC=CC=C1 FNIBSWRSKVEZDZ-UHFFFAOYSA-N 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001302 tertiary amino group Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Foreliggende oppfinnelse til- veiebringer nye anvendelser av forbin- delser med den generelle formel (I) a) hvor R\ R^ og R' uavhengig av hverandre er hydrogen, hydroksy, halogen,'tri- fluormetyl, lavere alkyl, lavere alk- oksy eller (tertiært amino)(lavere alk- oksy); og R^ og R^ uavhengig av hver- andre er hydrogen eller lavere alkyl, eller som et farmasøytisk akseptabelt salt derav, i kombinasjon med en farma- søytisk akseptabel bærer, til fremstil- ling av et farmasøytisk preparat for behandling eller profylakse av idio- patisk eller fysiologisk gynekomasti.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK4295 | 1995-01-13 | ||
| DK77395 | 1995-06-30 | ||
| PCT/DK1996/000012 WO1996021442A1 (en) | 1995-01-13 | 1996-01-10 | Use of 3,4-diphenyl chromans for the manufacture of a pharmaceutical composition for the treatment of prophylaxis of idiopathic or physiologic gynaecomastia |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO973242D0 NO973242D0 (no) | 1997-07-11 |
| NO973242L true NO973242L (no) | 1997-07-11 |
Family
ID=26063181
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO973242A NO973242L (no) | 1995-01-13 | 1997-07-11 | Anvendelse av 3,4-difenylkromaner til fremstilling av et farmasöytisk preparat for behandling eller profylakse av idiopatisk eller fysiologisk gynekomasti |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5919812A (no) |
| EP (1) | EP0809496A1 (no) |
| JP (1) | JPH10511960A (no) |
| CN (1) | CN1168097A (no) |
| AU (1) | AU702407B2 (no) |
| BR (1) | BR9606754A (no) |
| CA (1) | CA2208868A1 (no) |
| CZ (1) | CZ212497A3 (no) |
| HU (1) | HUP9800133A3 (no) |
| IL (1) | IL116747A (no) |
| NO (1) | NO973242L (no) |
| WO (1) | WO1996021442A1 (no) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6117911A (en) | 1997-04-11 | 2000-09-12 | Neorx Corporation | Compounds and therapies for the prevention of vascular and non-vascular pathologies |
| US6613083B2 (en) | 2001-05-02 | 2003-09-02 | Eckhard Alt | Stent device and method |
| US8080675B2 (en) | 2004-09-21 | 2011-12-20 | Marshall Edwards, Inc. | Chroman derivatives, medicaments and use in therapy |
| EP1794141B1 (en) | 2004-09-21 | 2011-11-09 | Marshall Edwards, Inc. | Substituted chroman derivatives, medicaments and use in therapy |
| US9708283B2 (en) | 2010-11-01 | 2017-07-18 | Mei Pharma, Inc. | Isoflavonoid compositions and methods for the treatment of cancer |
| SI2953938T1 (en) | 2014-02-07 | 2018-01-31 | Novogen Ltd. | Functionalized benzopyran compounds and their use |
| CN116139125A (zh) | 2015-02-02 | 2023-05-23 | 梅制药公司 | 联合治疗 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3822287A (en) * | 1969-04-17 | 1974-07-02 | Rexall Drug Chemical | Process for preparation of substituted 3,4-(diphenyl)chromans |
| US4447622A (en) * | 1981-09-22 | 1984-05-08 | Council Of Scientific And Industrial Research Rafi Marg | Preparation of l- and d-isomers of dl-3,4-trans-2,2-disubstituted-3,4-diarylchromans and derivatives thereof |
| US4895715A (en) * | 1988-04-14 | 1990-01-23 | Schering Corporation | Method of treating gynecomastia |
| US5364847A (en) * | 1989-03-10 | 1994-11-15 | Endorecherche | Inhibitors of sex steroid biosynthesis and methods for their production and use |
| US5280040A (en) * | 1993-03-11 | 1994-01-18 | Zymogenetics, Inc. | Methods for reducing bone loss using centchroman derivatives |
-
1996
- 1996-01-10 BR BR9606754A patent/BR9606754A/pt not_active Application Discontinuation
- 1996-01-10 CA CA002208868A patent/CA2208868A1/en not_active Abandoned
- 1996-01-10 CZ CZ972124A patent/CZ212497A3/cs unknown
- 1996-01-10 EP EP96900093A patent/EP0809496A1/en not_active Withdrawn
- 1996-01-10 HU HU9800133A patent/HUP9800133A3/hu unknown
- 1996-01-10 JP JP8521376A patent/JPH10511960A/ja active Pending
- 1996-01-10 AU AU43290/96A patent/AU702407B2/en not_active Ceased
- 1996-01-10 CN CN96191416A patent/CN1168097A/zh active Pending
- 1996-01-10 WO PCT/DK1996/000012 patent/WO1996021442A1/en not_active Ceased
- 1996-01-12 IL IL11674796A patent/IL116747A/xx active IP Right Grant
-
1997
- 1997-03-04 US US08/811,154 patent/US5919812A/en not_active Expired - Fee Related
- 1997-07-11 NO NO973242A patent/NO973242L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR9606754A (pt) | 1998-01-06 |
| US5919812A (en) | 1999-07-06 |
| JPH10511960A (ja) | 1998-11-17 |
| CA2208868A1 (en) | 1996-07-18 |
| MX9705218A (es) | 1997-10-31 |
| WO1996021442A1 (en) | 1996-07-18 |
| HUP9800133A3 (en) | 1999-12-28 |
| IL116747A0 (en) | 1996-05-14 |
| AU4329096A (en) | 1996-07-31 |
| HUP9800133A2 (hu) | 1998-12-28 |
| EP0809496A1 (en) | 1997-12-03 |
| CZ212497A3 (en) | 1997-11-12 |
| AU702407B2 (en) | 1999-02-18 |
| NO973242D0 (no) | 1997-07-11 |
| IL116747A (en) | 1999-11-30 |
| CN1168097A (zh) | 1997-12-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO20025821L (no) | 2-aminokarbonyl-9H-purinderivater | |
| BR0109703A (pt) | Derivados de piperazina | |
| DE60204452D1 (de) | Pyrazolo[1,5]pyridinderivate | |
| TR200102042T2 (tr) | Spiro fropiridinlerin, tedavide faydalı yeni aralkil aminleri. | |
| SE9903760D0 (sv) | New compounds | |
| SE9904505D0 (sv) | Novel compounds | |
| AP9701041A0 (en) | Pyridylpyrrole compounds. | |
| NO996108L (no) | 9-oksinerytromycinderivater | |
| MXPA03008215A (es) | Inhibidores de integrina alfa v beta 6. | |
| AU2002239348A1 (en) | Pyrazolopyridine derivatives | |
| NO973243L (no) | Anvendelse av 3,4-difenylkromaner til fremstilling av et farmasöytisk preparat for behandling eller profylakse av gynekologiske sykdommer | |
| NO984470L (no) | Pyrrolopyrrolon-derivater som inhibitorer for neutrofil elastase | |
| NO20050664L (no) | 2,4 substituerte indoler og anvendelse derav som 5-HT6 modulatorer | |
| NO983178L (no) | Anvendelse av 3,4-difenylkromaner til fremstilling av et farmasaytisk preparat for behandling eller profylakse av menopausesymptomer | |
| NO971625L (no) | Nye peptider med immunomodulatoriske effekter | |
| NO20050666L (no) | 2,7-substituerte indoler og deres anvendelse som 5-HT6 modulatorer | |
| AU2001290480A1 (en) | Cyclized benzamide neurokinin antagonists for use in therapy | |
| NO991230L (no) | Trisykliske forbindelser for inhibering av G-proteinfunksjon og for behandling av proliferative sykdommer | |
| NO973342L (no) | Anvendelse av 3,4-difenylkromaner til fremstilling av et farmasöytisk preparat for behandling eller profylakse av cerebrale degenerative sykdommer | |
| PL326554A1 (en) | Derivatives of amine and thiourea and inhibitors of nitrogen oxide synthase | |
| NO973242L (no) | Anvendelse av 3,4-difenylkromaner til fremstilling av et farmasöytisk preparat for behandling eller profylakse av idiopatisk eller fysiologisk gynekomasti | |
| NO973340L (no) | Anvendelse av 3,4-difenylkromaner til fremstilling av et farmasöytisk preparat for behandling eller profylakse av fedme | |
| DE69330601D1 (de) | Serotoninergische ergolin derivate | |
| AU2001261707A1 (en) | Pirazino '1$m(1)2$m(1) :1, 6! pyrido '3,4-b! indole derivatives | |
| NO973241L (no) | Anvendelse av 3,4-difenylkromaner til fremstilling av et farmasöytisk preparat for behandling eller profylakse av hyperlipoproteinemi, hypertriglyceridemi, hyperlipidemi eller hyperkolesterolemi, eller arteriosklerose, eller for antikoagulativ b |