NO971624D0 - Intracellulær isoform av interleukin-1 reseptor antagonist - Google Patents

Intracellulær isoform av interleukin-1 reseptor antagonist

Info

Publication number: NO971624D0
Authority: NO; Norway
Prior art keywords: interleukin; antagonist; receptor antagonist; new; intracellular isoform
Prior art date: 1994-10-13

Application number

NO971624A

Other languages

English (en)

Other versions

NO320494B1 (no

NO971624L (no

Inventor

Francesco Colotta

Marta Muzio

Alberto Montovani

Original Assignee

Applied Research Systems

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-10-13

Filing date

1997-04-09

Publication date

1997-04-09

1997-04-09 Application filed by Applied Research Systems filed Critical Applied Research Systems

1997-04-09 Publication of NO971624D0 publication Critical patent/NO971624D0/no

1997-05-30 Publication of NO971624L publication Critical patent/NO971624L/no

2005-12-12 Publication of NO320494B1 publication Critical patent/NO320494B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Genetics & Genomics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Zoology (AREA)
Molecular Biology (AREA)
Immunology (AREA)
Biochemistry (AREA)
Biomedical Technology (AREA)
Wood Science & Technology (AREA)
Biotechnology (AREA)
Gastroenterology & Hepatology (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
General Engineering & Computer Science (AREA)
Toxicology (AREA)
Oncology (AREA)
Virology (AREA)
Microbiology (AREA)
Rheumatology (AREA)
Communicable Diseases (AREA)
Hematology (AREA)
Diabetes (AREA)
Epidemiology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physics & Mathematics (AREA)
Pain & Pain Management (AREA)
Tropical Medicine & Parasitology (AREA)

NO19971624A 1994-10-13 1997-04-09 Renset protein med antagonistisk aktivitet mot minst en av forbindelsene valgt fra gruppen bestaende av interleukin-1-a og interleikun-1-b, isolert DNA sekvens, vektor, vertscelle, og fremgangsmater og anvendelser derav. NO320494B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
ITMI942097A IT1270662B (it)	1994-10-13	1994-10-13	Antagonista della interleuchina-1
PCT/EP1995/004023 WO1996012022A1 (en)	1994-10-13	1995-10-12	Intracellular isoform of the interleukin-1 receptor antagonist

Publications (3)

Publication Number	Publication Date
NO971624D0 true NO971624D0 (no)	1997-04-09
NO971624L NO971624L (no)	1997-05-30
NO320494B1 NO320494B1 (no)	2005-12-12

Family

ID=11369705

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19971624A NO320494B1 (no)	1994-10-13	1997-04-09	Renset protein med antagonistisk aktivitet mot minst en av forbindelsene valgt fra gruppen bestaende av interleukin-1-a og interleikun-1-b, isolert DNA sekvens, vektor, vertscelle, og fremgangsmater og anvendelser derav.

Country Status (18)

Country	Link
US (1)	US5739282A (no)
EP (1)	EP0786002B1 (no)
JP (1)	JPH10509306A (no)
KR (1)	KR100237936B1 (no)
CN (2)	CN1224707C (no)
AT (1)	ATE303439T1 (no)
BR (1)	BR9509317A (no)
CA (1)	CA2202470C (no)
DE (1)	DE69534419T2 (no)
EE (1)	EE03697B1 (no)
ES (1)	ES2243942T3 (no)
IT (1)	IT1270662B (no)
MX (1)	MX9702616A (no)
NO (1)	NO320494B1 (no)
PT (1)	PT786002E (no)
RU (1)	RU2193064C2 (no)
UA (1)	UA65522C2 (no)
WO (1)	WO1996012022A1 (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5075222A (en) *	1988-05-27	1991-12-24	Synergen, Inc.	Interleukin-1 inhibitors
US5872095A (en) *	1990-05-01	1999-02-16	Chiron Corporation	IL-1 receptor antagonists medicaments
SI0938500T1 (en)	1996-10-31	2005-02-28	Applied Research Systems Ars Holding N.V.	INTERLEUKIN-1beta-CONVERTING ENZYME (ICE) INHIBITING PEPTIDES
WO1998024477A1 (en) *	1996-12-06	1998-06-11	Amgen Inc.	Combination therapy using an il-1 inhibitor for treating il-1 mediated diseases
US6294170B1 (en)	1997-08-08	2001-09-25	Amgen Inc.	Composition and method for treating inflammatory diseases
IL126562A0 (en) *	1998-10-14	1999-08-17	Interpharm Lab Ltd	Expression and secretion of icil-1 receptor antagonist type ii
US20020077276A1 (en) *	1999-04-27	2002-06-20	Fredeking Terry M.	Compositions and methods for treating hemorrhagic virus infections and other disorders
US7166712B2 (en) *	2000-07-12	2007-01-23	Philadelphia, Health And Education Corporation	Mammalian MDM2 binding proteins and uses thereof
ES2967485T3 (es) *	2003-12-23	2024-04-30	Genentech Inc	Nuevos anticuerpos anti-IL 13 y usos de los mismos
EP2327413A1 (en)	2004-07-06	2011-06-01	ZymoGenetics, Inc.	Pharmaceutical composition comprising FGF18 and IL-1 antagonist and method of use
RU2326947C2 (ru) *	2004-11-23	2008-06-20	Общество с ограниченной ответственностью "ЦИТОКИН"	Способ получения рекомбинантного антагониста рецептора интерлейкина-1 человека "арил"
AU2007235199B8 (en) *	2006-01-31	2010-10-28	Novartis Ag	IL-17 antagonistic antibodies for treating cancer
WO2009062339A1 (en)	2007-11-14	2009-05-22	General Regeneratives, Ltd.	Methods of using interleukin-1 receptor antagonist as a myeloprotective agent
CN101690801B (zh)	2009-10-26	2012-08-01	上海交通大学	白细胞介素-1受体拮抗剂的用途及其药物组合物
ES2600616T3 (es)	2011-03-14	2017-02-10	Phlogo Aps	Antagonistas del receptor de la interleucina-1
CA2869786A1 (en)	2012-06-08	2013-12-12	Alkermes, Inc.	Fusion polypeptides comprising mucin-domain polypeptide linkers
WO2015191783A2 (en)	2014-06-10	2015-12-17	Abbvie Inc.	Biomarkers for inflammatory disease and methods of using same
KR20210091244A (ko) *	2018-11-15	2021-07-21	얀센 바이오테크 인코포레이티드	염증성 장 질환의 요법에 대한 반응의 예측을 위한 방법 및 조성물

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR0148009B1 (ko) *	1988-05-27	1998-08-01	그래고리 비. 아보트	인터루킨-1 억제제
EP0502956B1 (en) *	1989-11-29	1997-04-23	Amgen Boulder Inc.	Production of recombinant human interleukin-1 inhibitor
AU649245B2 (en) *	1990-04-02	1994-05-19	Amgen, Inc.	Methods for treating interleukin-1 mediated diseases
WO1991017184A1 (en) *	1990-04-27	1991-11-14	The Upjohn Company	Modified interleukin-1 inhibitors
AU655766B2 (en) *	1990-05-01	1995-01-12	Chiron Corporation	Interleukin-1 antagonist and uses thereof

1994
- 1994-10-13 IT ITMI942097A patent/IT1270662B/it active IP Right Grant
1995
- 1995-06-07 US US08/476,860 patent/US5739282A/en not_active Expired - Fee Related
- 1995-10-12 EP EP95936482A patent/EP0786002B1/en not_active Expired - Lifetime
- 1995-10-12 CA CA002202470A patent/CA2202470C/en not_active Expired - Fee Related
- 1995-10-12 ES ES95936482T patent/ES2243942T3/es not_active Expired - Lifetime
- 1995-10-12 DE DE69534419T patent/DE69534419T2/de not_active Expired - Fee Related
- 1995-10-12 KR KR1019970701931A patent/KR100237936B1/ko not_active Expired - Fee Related
- 1995-10-12 CN CNB951956647A patent/CN1224707C/zh not_active Expired - Fee Related
- 1995-10-12 WO PCT/EP1995/004023 patent/WO1996012022A1/en not_active Ceased
- 1995-10-12 RU RU97107461/13A patent/RU2193064C2/ru not_active IP Right Cessation
- 1995-10-12 CN CNB200510053993XA patent/CN100363053C/zh not_active Expired - Fee Related
- 1995-10-12 PT PT95936482T patent/PT786002E/pt unknown
- 1995-10-12 EE EE9700090A patent/EE03697B1/xx not_active IP Right Cessation
- 1995-10-12 JP JP8512932A patent/JPH10509306A/ja active Pending
- 1995-10-12 MX MX9702616A patent/MX9702616A/es not_active IP Right Cessation
- 1995-10-12 AT AT95936482T patent/ATE303439T1/de not_active IP Right Cessation
- 1995-10-12 BR BR9509317A patent/BR9509317A/pt not_active Application Discontinuation
- 1995-12-10 UA UA97052129A patent/UA65522C2/uk unknown
1997
- 1997-04-09 NO NO19971624A patent/NO320494B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
BR9509317A (pt)	1997-10-14
CN100363053C (zh)	2008-01-23
CN1224707C (zh)	2005-10-26
US5739282A (en)	1998-04-14
CN1679919A (zh)	2005-10-12
CA2202470C (en)	2008-09-16
PT786002E (pt)	2005-11-30
UA65522C2 (en)	2004-04-15
CN1161058A (zh)	1997-10-01
EE9700090A (et)	1997-10-15
ITMI942097A1 (it)	1996-04-13
HK1081124A1 (zh)	2006-05-12
AU701471B2 (en)	1999-01-28
DE69534419T2 (de)	2006-06-14
AU3841795A (en)	1996-05-06
HK1002659A1 (en)	1998-09-11
NO320494B1 (no)	2005-12-12
DE69534419D1 (de)	2005-10-06
IT1270662B (it)	1997-05-07
RU2193064C2 (ru)	2002-11-20
KR100237936B1 (ko)	2000-01-15
MX9702616A (es)	1998-04-30
EP0786002B1 (en)	2005-08-31
CA2202470A1 (en)	1996-04-25
ES2243942T3 (es)	2005-12-01
NO971624L (no)	1997-05-30
JPH10509306A (ja)	1998-09-14
WO1996012022A1 (en)	1996-04-25
EE03697B1 (et)	2002-04-15
ATE303439T1 (de)	2005-09-15
EP0786002A1 (en)	1997-07-30
KR970706391A (ko)	1997-11-03
ITMI942097A0 (it)	1994-10-13

Publication	Publication Date	Title
NO971624D0 (no)	1997-04-09	Intracellulær isoform av interleukin-1 reseptor antagonist
FI960727A0 (fi)	1996-02-16	Neurokiniiniantagonisteina käyttökelpoiset heterosyklit
HUP9702458A2 (hu)	1998-04-28	Humán interleukin-1-receptor járulékos fehérje
PT735818E (pt)	2004-07-30	Proteinas inflamatorias de macrofagos pim-3 pim-4 e pim-1y
DK0669979T3 (da)	2006-03-06	C-C CKR-1, kemokinreceptor
NO963280L (no)	1996-10-04	Anvendelse av anti-TNF antistoffer som legemidler i behandling av sykdommer som involverer forhöyede interleukin-6 serumnivåer
DK0751992T3 (da)	2006-03-06	Karendotelvækstfaktor 2
NO900227D0 (no)	1990-01-16	Ekstruderbar elastisk gel for anvendelse som baerer for terapeutisk middel.
TR199900318T2 (xx)	1999-05-21	IL-8 resept�r antagonistleri.
DE69432951D1 (de)	2003-08-21	Regulierung der fruchtbarkeit mit transformierendem wachstumfaktor beta
TR199700956T1 (xx)	1998-02-21	Indazolkarboksamidler.
TR200103448T2 (tr)	2002-06-21	IL-8 reseptör antagonistleri.
IT8820705A0 (it)	1988-05-24	Procedimento di calibrazione numerica di installazione di radiologia e installazione di calibrazione numerica per la messa in opera del procedimento.
IT1294932B1 (it)	1999-04-23	Uso di 2-amminotetraline-6,7 sostituite per la preparazione di composizioni farmaceutiche atte al trattamento di patologie
IT8321118U1 (it)	1984-09-15	Struttura di dispositivo implantologico, particolarmente per protesi dentarie e simili.
IT8430791V0 (it)	1984-07-12	Dispositivo per la sincronizzazione dello schienale particolarmente per poltrone di dentisti.
IT8430790U1 (it)	1986-01-12	Dispositivo orientabile per i comandi di movimento delle poltrone particolarmente per dentisti.
KR970004062U (ko)	1997-02-19	상·하 높낮이 조정이 자유로운 등받이 의자의 베개
KR900020697U (ko)	1990-12-13	초음파 가습기의 진동자용 고무링
IT8934028V0 (it)	1989-05-24	Struttura di supporto dello schienale di poltrone, divani e simili, variamente posizionabile.

Legal Events

Date	Code	Title	Description
2008-01-14	CREP	Change of representative	Representative=s name: ONSAGERS AS, POSTBOKS 6963 ST OLAVS PLASS, 0130 OS
2008-02-04	CREP	Change of representative	Representative=s name: ZACCO NORWAY AS, POSTBOKS 2003 VIKA, 0125 OSLO, NO
2010-05-31	MM1K	Lapsed by not paying the annual fees