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NO975600L - Early diagnostic test - Google Patents

Early diagnostic test

Info

Publication number
NO975600L
NO975600L NO975600A NO975600A NO975600L NO 975600 L NO975600 L NO 975600L NO 975600 A NO975600 A NO 975600A NO 975600 A NO975600 A NO 975600A NO 975600 L NO975600 L NO 975600L
Authority
NO
Norway
Prior art keywords
naturally occurring
cultured
early
disease
course
Prior art date
Application number
NO975600A
Other languages
Norwegian (no)
Other versions
NO975600D0 (en
Inventor
Hallie M Krider
Sandra Lee Bushmich
Original Assignee
Connaught Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/659,369 external-priority patent/US5985595A/en
Application filed by Connaught Lab filed Critical Connaught Lab
Publication of NO975600D0 publication Critical patent/NO975600D0/en
Publication of NO975600L publication Critical patent/NO975600L/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

En fremgangsmåte for å screene Lyme borreliosis og andre infeksjonssykdommer tidlig i sykdomsforløpet er vist. Det har blitt funnet at det er en dramatisk forskjell i overflatebinding i dyrkede infeksjonsmidler til naturlig forekommende polymorfonukleære- leukocyttet (PMNs) (feks nøytrofile) mellom infiserte og ikke-infiserte dyr, som kan være tilstede tidlig i sykdomsforløpet, før målbar antistoff respons. Denne bindingsresponsen kan raskt og nøyaktig bli skilt og kvatifisert ved å bruke forskjellige deteksjonsteknikker. Fremgangsmåten involverer visualisering av overflatebindingen av det dyrkede infeksjons- rnidlet til naturlig forekommende PMN for å detek- tere infeksjonen.A method for screening Lyme borreliosis and other infectious diseases early in the course of the disease is shown. It has been found that there is a dramatic difference in surface binding in cultured infectious agents to naturally occurring polymorphonuclear leukocytes (PMNs) (e.g., neutrophils) between infected and uninfected animals, which may be present early in the disease course, before measurable antibody response. This binding response can be quickly and accurately separated and quantified using different detection techniques. The method involves visualizing the surface binding of the cultured infection agent to naturally occurring PMN to detect the infection.

NO975600A 1995-06-07 1997-12-03 Early diagnostic test NO975600L (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US48718895A 1995-06-07 1995-06-07
US08/659,369 US5985595A (en) 1995-06-07 1996-06-06 Early detection of Borrelia infection
PCT/US1996/010040 WO1996040869A1 (en) 1995-06-07 1996-06-07 Early diagnostic test

Publications (2)

Publication Number Publication Date
NO975600D0 NO975600D0 (en) 1997-12-03
NO975600L true NO975600L (en) 1998-02-05

Family

ID=27048917

Family Applications (1)

Application Number Title Priority Date Filing Date
NO975600A NO975600L (en) 1995-06-07 1997-12-03 Early diagnostic test

Country Status (7)

Country Link
EP (1) EP0830449A1 (en)
JP (1) JP2001517921A (en)
AU (1) AU6272796A (en)
CA (1) CA2222886A1 (en)
FI (1) FI974424A7 (en)
NO (1) NO975600L (en)
WO (1) WO1996040869A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6093809A (en) * 1996-10-01 2000-07-25 University Technology Corporation Telomerase
HU220169B (en) * 1999-02-17 2001-11-28 Béla Pál Bózsik Reagent and process for microscopical detecting of microorganisms, first of all spirochetae in body liquors
RU2239191C2 (en) * 2002-04-24 2004-10-27 Касимова Нина Борисовна Method for evaluating indirect antigen-specific rosette-formation in neutrophils at astrakhan fever and viral hepatitis b
GB0315512D0 (en) * 2003-07-02 2003-08-06 Aeon Biotech Ltd Diagnostic test
US7682619B2 (en) 2006-04-06 2010-03-23 Cornell Research Foundation, Inc. Canine influenza virus
US9395365B2 (en) * 2009-04-02 2016-07-19 Abbott Point Of Care, Inc. Detection of infectious disease in a human or animal by measuring specific phagocytosis in a thin film sample of their anticoagulated blood
EP2657238A4 (en) 2010-12-24 2014-06-18 Univ Tohoku MACROLIDE HAVING AN ANTICANCER EFFECT

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4652521A (en) * 1985-03-04 1987-03-24 Regents Of The University Of Minnesota Method for the early diagnosis of bordetella diseases and kit therefor
US4888276A (en) * 1986-06-26 1989-12-19 Minnesota Mining And Manufacturing Company Method and composition for the diagnosis of Lyme disease

Also Published As

Publication number Publication date
WO1996040869A1 (en) 1996-12-19
EP0830449A1 (en) 1998-03-25
FI974424L (en) 1998-02-04
AU6272796A (en) 1996-12-30
FI974424A0 (en) 1997-12-05
JP2001517921A (en) 2001-10-09
FI974424A7 (en) 1998-02-04
CA2222886A1 (en) 1996-12-19
NO975600D0 (en) 1997-12-03

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application