NO961900L - Metylenblått for behandling eller profylakse av encefalopati forårsaket av ifosfamid - Google Patents
Metylenblått for behandling eller profylakse av encefalopati forårsaket av ifosfamidInfo
- Publication number
- NO961900L NO961900L NO961900A NO961900A NO961900L NO 961900 L NO961900 L NO 961900L NO 961900 A NO961900 A NO 961900A NO 961900 A NO961900 A NO 961900A NO 961900 L NO961900 L NO 961900L
- Authority
- NO
- Norway
- Prior art keywords
- ifosfamide
- methylene blue
- prophylaxis
- treatment
- encephalopathy caused
- Prior art date
Links
- HOMGKSMUEGBAAB-UHFFFAOYSA-N ifosfamide Chemical compound ClCCNP1(=O)OCCCN1CCCl HOMGKSMUEGBAAB-UHFFFAOYSA-N 0.000 title abstract 3
- 229960001101 ifosfamide Drugs 0.000 title abstract 3
- RBTBFTRPCNLSDE-UHFFFAOYSA-N 3,7-bis(dimethylamino)phenothiazin-5-ium Chemical compound C1=CC(N(C)C)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 RBTBFTRPCNLSDE-UHFFFAOYSA-N 0.000 title abstract 2
- 208000014644 Brain disease Diseases 0.000 title abstract 2
- 208000032274 Encephalopathy Diseases 0.000 title abstract 2
- 229960000907 methylthioninium chloride Drugs 0.000 title abstract 2
- 238000011321 prophylaxis Methods 0.000 title 1
- 238000011282 treatment Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004072 flavinyl group Chemical group 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- SIXLXDIJGIWWFU-UHFFFAOYSA-N pyritinol Chemical compound OCC1=C(O)C(C)=NC=C1CSSCC1=CN=C(C)C(O)=C1CO SIXLXDIJGIWWFU-UHFFFAOYSA-N 0.000 abstract 1
- 229960004986 pyritinol Drugs 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Den encefalopati som forår- sakes av ifosfamid og lignende virkende forbindelser, kan forhindres eller be- handles ved administrering av metylen- blått eller en annen forbindelse som er i stand til å oksidere en redusert flavinrest. Pyritinol er i stand til å redusere andre aspekter av ifosfamid- toksisitet.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939323399A GB9323399D0 (en) | 1993-11-12 | 1993-11-12 | Pharmaceutical formulations |
| PCT/GB1994/002494 WO1995013079A1 (en) | 1993-11-12 | 1994-11-14 | Methylene blue for the treatment or prophylaxis of ancephalopathy caused by ifosfamide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO961900L true NO961900L (no) | 1996-05-10 |
| NO961900D0 NO961900D0 (no) | 1996-05-10 |
Family
ID=10745089
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO961900A NO961900D0 (no) | 1993-11-12 | 1996-05-10 | Metylenblått for behandling eller profylakse av encefalopati forårsaket av ifosfamid |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5854240A (no) |
| EP (1) | EP0728005A1 (no) |
| JP (1) | JPH09505042A (no) |
| CN (1) | CN1134670A (no) |
| AU (1) | AU8149594A (no) |
| CA (1) | CA2176386A1 (no) |
| GB (1) | GB9323399D0 (no) |
| NO (1) | NO961900D0 (no) |
| WO (1) | WO1995013079A1 (no) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0017060D0 (en) * | 2000-07-11 | 2000-08-30 | Hunter Fleming Ltd | Production, stabilisation and use of reduced forms of pharmaceutical compounds |
| US7176192B2 (en) * | 2001-10-26 | 2007-02-13 | Bionumerik Pharmaceuticals, Inc. | Method for treating patients for radiation exposure |
| CA2379211A1 (fr) * | 2002-03-28 | 2003-09-28 | Institut De Cardiologie De Montreal | Utilisation du bleu de methylene pour renverser la reaction hemodynamique exageree induite par la combinaison d'un derive nitre et du sildenafil ou d'une molecule de meme classe (inhibiteur de la phosphodiesterase) |
| US20060188866A1 (en) * | 2005-02-18 | 2006-08-24 | Children's Hospital Oakland Research Institute | Diaminophenothiazine compositions and uses thereof |
| GR1006794B (el) * | 2009-02-26 | 2010-06-04 | Αλεξανδρος Βαμβακιδης | Προσδετες των σιγμα υποδοχεων, αντι-αποπτωτικες και προ-αποπτωτικες ιδιοτητες επι των κυτταρικων μηχανισμων, και με πρωτοτυπη κυτταρο-προστατευτικη αλλα και αντικαρκινικη δραση |
| JP2010184936A (ja) * | 2010-06-01 | 2010-08-26 | Bionumerik Pharmaceuticals Inc | 放射線被爆患者の処置方法 |
| JPWO2021095696A1 (no) * | 2019-11-11 | 2021-05-20 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1645921C3 (de) * | 1966-07-11 | 1978-10-12 | Asta-Werke Ag Chemische Fabrik, 4800 Bielefeld | 2-Oxo-13,2-osazaphosphorinane, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate |
| US4548927A (en) * | 1983-05-25 | 1985-10-22 | Eaton John W | Method and agents for raising animal tolerance to oxidant stress-inducing antibiotics |
| EP0248803A4 (en) * | 1985-02-12 | 1988-01-21 | Commw Scient Ind Res Org | VOLTAMETRIC CELL. |
-
1993
- 1993-11-12 GB GB939323399A patent/GB9323399D0/en active Pending
-
1994
- 1994-11-14 CA CA002176386A patent/CA2176386A1/en not_active Abandoned
- 1994-11-14 AU AU81495/94A patent/AU8149594A/en not_active Abandoned
- 1994-11-14 JP JP7513703A patent/JPH09505042A/ja active Pending
- 1994-11-14 EP EP95900837A patent/EP0728005A1/en not_active Withdrawn
- 1994-11-14 CN CN94194079A patent/CN1134670A/zh active Pending
- 1994-11-14 WO PCT/GB1994/002494 patent/WO1995013079A1/en not_active Ceased
- 1994-11-14 US US08/646,292 patent/US5854240A/en not_active Expired - Fee Related
-
1996
- 1996-05-10 NO NO961900A patent/NO961900D0/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US5854240A (en) | 1998-12-29 |
| CA2176386A1 (en) | 1995-05-18 |
| CN1134670A (zh) | 1996-10-30 |
| EP0728005A1 (en) | 1996-08-28 |
| GB9323399D0 (en) | 1994-01-05 |
| WO1995013079A1 (en) | 1995-05-18 |
| AU8149594A (en) | 1995-05-29 |
| JPH09505042A (ja) | 1997-05-20 |
| NO961900D0 (no) | 1996-05-10 |
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