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NO961333L - Nye pyrazolderivater som angiotensin-II-antagonister - Google Patents

Nye pyrazolderivater som angiotensin-II-antagonister

Info

Publication number
NO961333L
NO961333L NO961333A NO961333A NO961333L NO 961333 L NO961333 L NO 961333L NO 961333 A NO961333 A NO 961333A NO 961333 A NO961333 A NO 961333A NO 961333 L NO961333 L NO 961333L
Authority
NO
Norway
Prior art keywords
angiotensin
antagonists
pyrazole derivatives
novel pyrazole
compounds
Prior art date
Application number
NO961333A
Other languages
English (en)
Other versions
NO961333D0 (no
Inventor
Carmen Almansa
Concepcion Gonzalez
Maria Carmen Torres
Elena Carceller
Javier Bartroli
Original Assignee
Uriach & Cia Sa J
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uriach & Cia Sa J filed Critical Uriach & Cia Sa J
Publication of NO961333D0 publication Critical patent/NO961333D0/no
Publication of NO961333L publication Critical patent/NO961333L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)

Abstract

Forbindelser med generell formel I og deres salter og solvater er angiotensin II receptorantagonister og kan som sådan brukes ved behandling av hypertensjon, kongestiv hjertesvikt og forhøyet øyetrykk. Oppfinnelsen tilveiebringer også farmasøytiske blandinger som inneholder disse forbindelser foruten fremgangsmåter for deres fremstilling.
NO961333A 1994-08-02 1996-04-01 Nye pyrazolderivater som angiotensin-II-antagonister NO961333L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES09401711A ES2105939B1 (es) 1994-08-02 1994-08-02 Nuevos pirazoles con actividad antagonista de la angiotensina ii.
PCT/EP1995/003086 WO1996004273A1 (en) 1994-08-02 1995-08-02 New pyrazole derivatives as angiotensin ii antagonist

Publications (2)

Publication Number Publication Date
NO961333D0 NO961333D0 (no) 1996-04-01
NO961333L true NO961333L (no) 1996-04-01

Family

ID=8287143

Family Applications (1)

Application Number Title Priority Date Filing Date
NO961333A NO961333L (no) 1994-08-02 1996-04-01 Nye pyrazolderivater som angiotensin-II-antagonister

Country Status (8)

Country Link
US (1) US5827863A (no)
EP (1) EP0721454A1 (no)
JP (1) JPH09504804A (no)
AU (1) AU3256395A (no)
CA (1) CA2173258A1 (no)
ES (1) ES2105939B1 (no)
NO (1) NO961333L (no)
WO (1) WO1996004273A1 (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4432860A1 (de) * 1994-09-15 1996-03-21 Merck Patent Gmbh Imidazopyridine
DE19645313A1 (de) 1996-11-04 1998-05-07 Basf Ag Substituierte 3-Benzylpyrazole
SE9903028D0 (sv) * 1999-08-27 1999-08-27 Astra Ab New use
DK1216038T3 (da) * 1999-08-30 2005-12-27 Sanofi Aventis Deutschland Anvendelse af inhibitorer af reninangiotensinsystemet ved forebyggelsen af cardiovaskulære hændelser
HU222773B1 (hu) * 2000-04-21 2003-10-28 Richter Gedeon Vegyészeti Gyár Rt. Eljárás egy ismert tetrazolszármazék előállítására
DE10105916A1 (de) * 2001-02-09 2002-08-22 Siemens Ag Amorphe organische 1,3,2-Dioxaborinluminophore, Verfahren zu deren Herstellung und Verwendung davon
US7107198B2 (en) * 2001-11-02 2006-09-12 Sun Microsystems, Inc. Automatic generation of reduced-size circuit models including inductive interaction
WO2008093639A1 (ja) 2007-01-29 2008-08-07 Takeda Pharmaceutical Company Limited ピラゾール化合物
JP5833000B2 (ja) * 2009-07-07 2015-12-16 セラヴァンス バイオファーマ アール＆ディー アイピー， エルエルシー 二重に作用するピラゾール抗高血圧症薬
CN103772282B (zh) * 2014-02-26 2015-09-23 上海毕得医药科技有限公司 一种3-叔丁基-1h-吡唑-4-甲醛的制备方法
WO2016035328A1 (ja) * 2014-09-01 2016-03-10 キヤノン株式会社 化合物、分散剤及びトナー
AR134016A1 (es) * 2023-10-06 2025-11-26 Sumitomo Chemical Co Compuestos de biarilo y método para controlar enfermedades vegetales

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5189048A (en) * 1988-01-07 1993-02-23 E. I. Du Pont De Nemours And Company Substituted 1,2,3 triazole angiotensin II antagonists
GB9005354D0 (en) * 1990-03-09 1990-05-02 Glaxo Group Ltd Chemical compounds
WO1993005025A1 (en) * 1991-09-06 1993-03-18 Glaxo Group Limited C-linked pyrazole derivatives
AT398202B (de) * 1991-10-04 1994-10-25 Chem Pharm Forsch Gmbh Neue imidazolderivate, verfahren zu ihrer herstellung und ihre verwendung

Also Published As

Publication number Publication date
US5827863A (en) 1998-10-27
EP0721454A1 (en) 1996-07-17
WO1996004273A1 (en) 1996-02-15
CA2173258A1 (en) 1996-02-15
JPH09504804A (ja) 1997-05-13
NO961333D0 (no) 1996-04-01
ES2105939A1 (es) 1997-10-16
AU3256395A (en) 1996-03-04
ES2105939B1 (es) 1998-07-01

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