NO964007L - Kombinasjoner av trombolytisk aktive proteiner og antikoagulanter samt anvendelse derav - Google Patents

Kombinasjoner av trombolytisk aktive proteiner og antikoagulanter samt anvendelse derav

Info

Publication number: NO964007L
Authority: NO; Norway
Prior art keywords: thrombolytically; thrombolytically active; anticoagulants; combinations; anticoagulant
Prior art date: 1994-03-25

Application number

NO964007A

Other languages

English (en)

Other versions

NO316584B1 (no

NO964007D0 (no

Inventor

Ulrich Martin

Stephan Fischer

Original Assignee

Boehringer Mannheim Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-03-25

Filing date

1996-09-24

Publication date

1996-11-25

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22811809&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO964007(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1996-09-24 Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh

1996-09-24 Publication of NO964007D0 publication Critical patent/NO964007D0/no

1996-11-25 Publication of NO964007L publication Critical patent/NO964007L/no

2004-03-01 Publication of NO316584B1 publication Critical patent/NO316584B1/no

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
- A61K38/58—Protease inhibitors from animals; from humans from leeches, e.g. hirudin, eglin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/49—Urokinase; Tissue plasminogen activator
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Epidemiology (AREA)
Gastroenterology & Hepatology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Biomedical Technology (AREA)
Zoology (AREA)
Tropical Medicine & Parasitology (AREA)
Urology & Nephrology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Vascular Medicine (AREA)
Diabetes (AREA)
Hematology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

NO19964007A 1994-03-25 1996-09-24 Kombinasjon av trombolytisk aktive proteiner og antikoagulanter samt anvendelse derav NO316584B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/217,618 US5510330A (en)	1994-03-25	1994-03-25	Combinations of thrombolytically active proteins and non-heparin anticoagulants, and uses thereof.
PCT/EP1995/001061 WO1995026202A1 (en)	1994-03-25	1995-03-22	Combinations of thrombolytically active proteins and anticoagulants, and uses thereof

Publications (3)

Publication Number	Publication Date
NO964007D0 NO964007D0 (no)	1996-09-24
NO964007L true NO964007L (no)	1996-11-25
NO316584B1 NO316584B1 (no)	2004-03-01

Family

ID=22811809

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19964007A NO316584B1 (no)	1994-03-25	1996-09-24	Kombinasjon av trombolytisk aktive proteiner og antikoagulanter samt anvendelse derav

Country Status (21)

Country	Link
US (1)	US5510330A (no)
EP (2)	EP0850648A3 (no)
JP (1)	JPH09510439A (no)
KR (1)	KR100366982B1 (no)
CN (1)	CN1090029C (no)
AT (1)	ATE167631T1 (no)
AU (1)	AU702470B2 (no)
BR (1)	BR9507189A (no)
CA (1)	CA2186390A1 (no)
CZ (1)	CZ279596A3 (no)
DE (1)	DE69503120T3 (no)
DK (1)	DK0751785T4 (no)
ES (1)	ES2119411T5 (no)
FI (1)	FI120182B (no)
MX (1)	MX9603925A (no)
NO (1)	NO316584B1 (no)
NZ (1)	NZ282417A (no)
PL (1)	PL182165B1 (no)
RU (1)	RU2166326C2 (no)
UA (1)	UA41398C2 (no)
WO (1)	WO1995026202A1 (no)

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US20070203520A1 (en) *	1995-06-07	2007-08-30	Dennis Griffin	Endovascular filter
US7846202B2 (en)	1995-06-07	2010-12-07	Cook Incorporated	Coated implantable medical device
US6774278B1 (en) *	1995-06-07	2004-08-10	Cook Incorporated	Coated implantable medical device
US7550005B2 (en)	1995-06-07	2009-06-23	Cook Incorporated	Coated implantable medical device
US7867275B2 (en) *	1995-06-07	2011-01-11	Cook Incorporated	Coated implantable medical device method
US7896914B2 (en) *	1995-06-07	2011-03-01	Cook Incorporated	Coated implantable medical device
US7611533B2 (en) *	1995-06-07	2009-11-03	Cook Incorporated	Coated implantable medical device
US5840733A (en) *	1996-07-01	1998-11-24	Redcell, Canada, Inc.	Methods and compositions for producing novel conjugates of thrombin inhibitors and endogenous carriers resulting in anti-thrombins with extended lifetimes
US6010911A (en) *	1997-04-30	2000-01-04	Medtronic, Inc.	Apparatus for performing a heparin-independent high sensitivity platelet function evaluation technique
US6750201B1 (en) *	1997-10-17	2004-06-15	The Trustees Of The University Of Pennsylvania	Compositions and methods for promoting internalization and degradation of urokinase-type plasminogen activator
US6517814B2 (en)	2001-01-09	2003-02-11	Bristol-Myers Squibb Pharma Company	Macrocyclic chelants useful for metallopharmaceuticals
DE10115740A1 (de) *	2001-03-26	2002-10-02	Ulrich Speck	Zubereitung für die Restenoseprophylaxe
DE10153601A1 (de) *	2001-11-02	2003-05-22	Paion Gmbh	DSPA zur Behandlung von Schlaganfall
FI20020197A0 (fi) *	2002-02-01	2002-02-01	Orion Corp	Yhdistelmä akuutin myokardiilisen infarktin hoitoon
US7084118B2 (en) *	2002-02-22	2006-08-01	Genentech, Inc.	Combination treatment with t-PA variant and low molecular weight heparin
DE60335801D1 (de) *	2002-07-12	2011-03-03	Cook William Europ	Beschichtete medizinische vorrichtung
DE10244847A1 (de) *	2002-09-20	2004-04-01	Ulrich Prof. Dr. Speck	Medizinische Vorrichtung zur Arzneimittelabgabe
ES2375064T3 (es) *	2004-05-17	2012-02-24	Medtronic, Inc.	Sistema de determinación de heparina en el lugar de atención al paciente.
US20060222640A1 (en) *	2005-03-29	2006-10-05	Boehringer Ingelheim International Gmbh	New pharmaceutical compositions for treatment of thrombosis
CN101522206B (zh) *	2006-10-06	2013-03-27	旭化成制药株式会社	弥散性血管内凝血综合征的治疗剂和/或改善剂
RU2371215C2 (ru) *	2007-08-13	2009-10-27	ГОУ ВПО "Саратовский ГМУ Росздрава"	Способ коррекции нарушенной функциональной активности гликопротеидных рецепторов тромбоцитов
AR068914A1 (es) *	2007-10-18	2009-12-16	Paion Deutschland Gmbh	Uso de un activador de plasminogeno para la preparacion de un medicamento para el tratamiento de apoplejia
EP2231702A1 (en) *	2007-12-21	2010-09-29	Ifxa A/s	Protease inhibitor
RU2394611C1 (ru) *	2009-06-05	2010-07-20	Алексей Николаевич Иванов	Способ коррекции нарушенной функциональной активности гликопротеидных рецепторов эритроцитов
MX383561B (es)	2014-11-03	2025-03-14	Thrombolytic Science Llc	Composiciones y kits para usarse en el tratamiento de un sujeto con síntomas de accidente cerebrovascular o infarto agudo de miocardio (iam).
KR101721068B1 (ko) *	2015-01-30	2017-03-29	고려대학교 산학협력단	베르베논 유도체 및 재관류 치료제를 포함하는 뇌혈관 질환, 동맥경화증 또는 심혈관 질환 치료 또는 예방용 병용 제제
RU2622006C2 (ru) *	2015-06-15	2017-06-08	Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Казанский (Приволжский) федеральный университет" (ФГАОУВПО КФУ)	Применение рекомбинантного штамма bacillus subtilis eo-11 вкпм в-11978 в качестве продуцента субтилизиноподобной протеиназы, вещества с тромболитическими и антикоагулянтными свойствами
CN105396127A (zh) *	2015-11-13	2016-03-16	中国人民解放军第四军医大学	一种用于急性心肌梗死的冠状动脉溶栓剂
WO2018232305A1 (en) *	2017-06-16	2018-12-20	Thrombolytic Science, Llc	Methods and compositions for thrombolysis
CN114292765B (zh) *	2021-09-24	2023-04-07	江西康之康中药科技有限公司	枯草芽孢杆菌纳豆亚种r3及其在发酵水蛭低温干燥品中的应用

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GB8508717D0 (en) *	1985-04-03	1985-05-09	Beecham Group Plc	Composition
DK43387A (da) †	1986-01-29	1987-07-30	Beecham Group Plc	Fibrinolytisk enzym
US5084274A (en) *	1987-11-17	1992-01-28	Scripps Clinic And Research Foundation	Inhibition of arterial thrombotic occlusion or thromboembolism
DE3804600A1 (de) *	1988-02-13	1989-08-24	Basf Ag	Mischung aus einer thrombolytisch wirkenden und einer antithrombotischen substanz
GB8822147D0 (en) *	1988-09-21	1988-10-26	Ciba Geigy Ag	Pharmaceutically active combination
US5204323B1 (en) *	1988-10-06	1995-07-18	Ciba Geigy Corp	Hirudin antidotal compositions and methods
GB8826428D0 (en) *	1988-11-11	1988-12-14	Biopharm Ltd	Antithrombin
US4980165A (en) *	1989-01-27	1990-12-25	Genetics Institute, Inc.	Pharmaceutical formulations of plasminogen activator proteins
DE3903581A1 (de) *	1989-02-07	1990-08-16	Boehringer Mannheim Gmbh	Gewebs-plasminogenaktivator-derivat
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US5196404B1 (en) *	1989-08-18	1996-09-10	Biogen Inc	Inhibitors of thrombin
US5240913A (en) *	1989-08-18	1993-08-31	Biogen, Inc.	Inhibitors of thrombin
US5049132A (en) *	1990-01-08	1991-09-17	Cordis Corporation	Balloon catheter for delivering therapeutic agents
US5189019A (en) *	1990-04-23	1993-02-23	Merck & Co., Inc.	Antistasin derived anticoagulant protein
US5242810A (en) *	1990-12-07	1993-09-07	Biogen, Inc.	Bifunctional inhibitors of thrombin and platelet activation
US5242688A (en) *	1990-12-24	1993-09-07	Eli Lilly And Company	Method of treating thromboembolic disorders by administration of diglycosylated t-pa variants
DK0580685T3 (da) †	1991-04-16	1996-03-04	Boehringer Mannheim Gmbh	Farmaceutisk emballageenhed indeholdende plasminogenaktivatorer til flerfoldig bolusindgift
ES2107041T3 (es) †	1992-06-03	1997-11-16	Genentech Inc	Variantes de activador de plasminogeno tisular obtenidos por glicosilacion, que presentan propiedades terapeuticas.
GB9303275D0 (en) *	1993-02-18	1993-04-07	Ciba Geigy Ag	Pharmaceutical compositions
IT1266561B1 (it) *	1993-07-22	1997-01-09	Mini Ricerca Scient Tecnolog	Analoghi di un polipeptide anti-trombinico e procedimento per la loro preparazione

1994
- 1994-03-25 US US08/217,618 patent/US5510330A/en not_active Expired - Lifetime
1995
- 1995-03-22 PL PL95316449A patent/PL182165B1/pl not_active IP Right Cessation
- 1995-03-22 EP EP98102473A patent/EP0850648A3/en not_active Ceased
- 1995-03-22 UA UA96104031A patent/UA41398C2/uk unknown
- 1995-03-22 KR KR1019960705381A patent/KR100366982B1/ko not_active Expired - Fee Related
- 1995-03-22 MX MX9603925A patent/MX9603925A/es not_active IP Right Cessation
- 1995-03-22 RU RU96119944/14A patent/RU2166326C2/ru not_active IP Right Cessation
- 1995-03-22 CA CA002186390A patent/CA2186390A1/en not_active Abandoned
- 1995-03-22 WO PCT/EP1995/001061 patent/WO1995026202A1/en not_active Ceased
- 1995-03-22 BR BR9507189A patent/BR9507189A/pt not_active Application Discontinuation
- 1995-03-22 AT AT95912261T patent/ATE167631T1/de active
- 1995-03-22 CZ CZ962795A patent/CZ279596A3/cs unknown
- 1995-03-22 NZ NZ282417A patent/NZ282417A/en not_active IP Right Cessation
- 1995-03-22 DK DK95912261T patent/DK0751785T4/da active
- 1995-03-22 ES ES95912261T patent/ES2119411T5/es not_active Expired - Lifetime
- 1995-03-22 EP EP95912261A patent/EP0751785B2/en not_active Expired - Lifetime
- 1995-03-22 CN CN95192275A patent/CN1090029C/zh not_active Expired - Fee Related
- 1995-03-22 JP JP7519775A patent/JPH09510439A/ja active Pending
- 1995-03-22 DE DE69503120T patent/DE69503120T3/de not_active Expired - Lifetime
- 1995-03-22 AU AU19511/95A patent/AU702470B2/en not_active Ceased
1996
- 1996-09-24 NO NO19964007A patent/NO316584B1/no not_active IP Right Cessation
- 1996-09-24 FI FI963802A patent/FI120182B/fi not_active IP Right Cessation

Also Published As

Publication number	Publication date
DK0751785T4 (da)	2002-04-15
CN1090029C (zh)	2002-09-04
MX9603925A (es)	1997-04-30
NZ282417A (en)	1998-02-26
CZ279596A3 (cs)	1998-01-14
DE69503120D1 (de)	1998-07-30
FI963802A0 (fi)	1996-09-24
DE69503120T2 (de)	1998-11-12
ES2119411T5 (es)	2002-08-01
AU702470B2 (en)	1999-02-25
PL182165B1 (pl)	2001-11-30
EP0850648A2 (en)	1998-07-01
ES2119411T3 (es)	1998-10-01
PL316449A1 (en)	1997-01-20
KR100366982B1 (ko)	2003-08-02
JPH09510439A (ja)	1997-10-21
BR9507189A (pt)	1997-09-09
ATE167631T1 (de)	1998-07-15
NO316584B1 (no)	2004-03-01
EP0751785B1 (en)	1998-06-24
FI963802L (fi)	1996-09-24
RU2166326C2 (ru)	2001-05-10
EP0751785A1 (en)	1997-01-08
FI120182B (fi)	2009-07-31
DK0751785T3 (da)	1999-04-06
UA41398C2 (uk)	2001-09-17
DE69503120T3 (de)	2003-08-14
CA2186390A1 (en)	1995-10-05
US5510330A (en)	1996-04-23
CN1144489A (zh)	1997-03-05
WO1995026202A1 (en)	1995-10-05
NO964007D0 (no)	1996-09-24
EP0751785B2 (en)	2001-12-19
AU1951195A (en)	1995-10-17
EP0850648A3 (en)	2004-03-31

Publication	Publication Date	Title
NO964007L (no)	1996-11-25	Kombinasjoner av trombolytisk aktive proteiner og antikoagulanter samt anvendelse derav
ES2168302T3 (es)	2002-06-16	Tratamiento de trastornos y estados neuromusculares con toxina botulinica de serotipo e.
CZ285522B6 (cs)	1999-08-11	Farmaceutický prostředek pro snížení koncentrace glukosy v krvi
ES2143641T3 (es)	2000-05-16	Expresion en superficie de una enzima en la terapia genica a base de promedicamentos.
ATE358176T1 (de)	2007-04-15	Menschliche dnase
CY1113355T1 (el)	2016-06-22	Χρηση θεραπειας νευροτοξινης για θεραπευτικη αγωγη ουρολογικων και σχετικων διαταραχων
DE69524864D1 (de)	2002-02-07	4-amino-derivate der mycophenolsäure mit immun suppressiver wirkung
IT8819693A0 (it)	1988-03-08	Apparecchio atto ad operare, in modo pressoche' istantaneo, la distruzione completa dell'ago di siringhe per iniezione, subito dopo il loro impiego.
DK0839026T3 (da)	2002-01-21	Micellære polyether-blokcopolymerkompositioner til målretning af biologiske midler
DE69233760D1 (de)	2009-06-25	Inhibitoren der menschlichen Elastase von Neutrophilen
CY1107314T1 (el)	2012-11-21	Μεθοδος θεpαπευτικης αγωγης ασθενων προσβεβλημενων με σκληρυνση κατα πλακας χρησιμοποιωντας συναινετικη ιντepφepονη
NO972391D0 (no)	1997-05-26	2-substituerte 1,2,5-tiadiazolidin-3-on 1,1-dioksider og preparater og metoder for anvendelse derav
ATE173627T1 (de)	1998-12-15	Medizinische zusammensetzung
NO994165L (no)	1999-10-25	Anvendelse av deskarboetoksyloratadin for fremstilling av et medikament for behandling av urininkontinens, reisesyke og svimmelhet
DE69008513D1 (de)	1994-06-01	Pharmazeutische formulierung von plasminogenaktivatorproteinen.
EP0671414A4 (en)	1995-11-15	ANTITHROMBOTIC.
FI953565A7 (fi)	1995-07-26	Uusi antikoagulanttikofaktoriaktiivisuus
TR199903192T2 (xx)	2000-05-22	Eritropoetin, de�i�tirilmi� hemoglobin i�eren farmasotik kombine m�stahzarlar.
PT88539A (pt)	1988-10-01	Stabilisierung von therapeutisch wirksamen proteinen in pharmazeutischen zubereitungen
DK34687D0 (da)	1987-01-22	Laegemiddel til nasal anvendelse, dets fremstilling og anvendelse
ATE187890T1 (de)	2000-01-15	Ligandgerichtete enzyme-prodrug therapie
ATE143809T1 (de)	1996-10-15	Placentaextrakt und verfahren zu seiner herstellung
DE3773322D1 (de)	1991-10-31	Pharmazeutische zubereitungen mit heilender aktivitaet.
BR6802637U (pt)	1990-08-07	Cheque personalizado,com garantias de autenticidade, utilizavel pelos estabelecimentos de segmento farmaceutico e seu desenvolvimento operacional
EA199800820A1 (ru)	1999-02-25	Способ лечения злоупотребления лекарственными средствами

Legal Events

Date	Code	Title	Description
2010-04-06	CREP	Change of representative	Representative=s name: ZACCO NORWAY AS, POSTBOKS 2003 VIKA
2013-10-28	MM1K	Lapsed by not paying the annual fees