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NO950374D0 - Terfenadinmetabolitter og deres optisk rene isomerer for behandling av allergiske sykdommer - Google Patents

Terfenadinmetabolitter og deres optisk rene isomerer for behandling av allergiske sykdommer

Info

Publication number
NO950374D0
NO950374D0 NO950374A NO950374A NO950374D0 NO 950374 D0 NO950374 D0 NO 950374D0 NO 950374 A NO950374 A NO 950374A NO 950374 A NO950374 A NO 950374A NO 950374 D0 NO950374 D0 NO 950374D0
Authority
NO
Norway
Prior art keywords
treatment
optically pure
allergic diseases
pure isomers
terfenadine metabolites
Prior art date
Application number
NO950374A
Other languages
English (en)
Other versions
NO310644B1 (no
NO950374L (no
Inventor
James W Young
Nancy M Gray
Raymond L Woosley
Yiwang Chen
Original Assignee
Sepracor Inc
Univ Georgetown
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27129882&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO950374(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sepracor Inc, Univ Georgetown filed Critical Sepracor Inc
Publication of NO950374D0 publication Critical patent/NO950374D0/no
Publication of NO950374L publication Critical patent/NO950374L/no
Publication of NO310644B1 publication Critical patent/NO310644B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Epoxy Compounds (AREA)
NO19950374A 1992-08-03 1995-02-01 Anvendelse av terfenadinmetabolitt og dens optisk rene isomerer for fremstilling av et farmasöytisk preparat forbehandling av allergisk rhinitt NO310644B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92418292A 1992-08-03 1992-08-03
US92415692A 1992-08-03 1992-08-03
PCT/US1993/007260 WO1994003170A1 (en) 1992-08-03 1993-08-03 Terfenadine metabolites and their optically pure isomers for treating allergic disorders

Publications (3)

Publication Number Publication Date
NO950374D0 true NO950374D0 (no) 1995-02-01
NO950374L NO950374L (no) 1995-03-29
NO310644B1 NO310644B1 (no) 2001-08-06

Family

ID=27129882

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19950374A NO310644B1 (no) 1992-08-03 1995-02-01 Anvendelse av terfenadinmetabolitt og dens optisk rene isomerer for fremstilling av et farmasöytisk preparat forbehandling av allergisk rhinitt

Country Status (24)

Country Link
US (1) US5375693A (no)
EP (4) EP1214937B1 (no)
JP (6) JP3041954B2 (no)
KR (1) KR950702420A (no)
AT (3) ATE322899T1 (no)
AU (3) AU675240B2 (no)
BR (1) BR9306841A (no)
CA (1) CA2141572C (no)
CZ (1) CZ27495A3 (no)
DE (5) DE701443T1 (no)
DK (3) DK0701443T4 (no)
ES (3) ES2257757T3 (no)
FI (1) FI950467L (no)
GB (1) GB2284351B (no)
GR (3) GR960300024T1 (no)
HK (1) HK1045806B (no)
HU (1) HU226242B1 (no)
NO (1) NO310644B1 (no)
PL (1) PL174373B1 (no)
PT (2) PT815860E (no)
RO (1) RO116043B1 (no)
RU (1) RU2167657C2 (no)
SK (1) SK12495A3 (no)
WO (1) WO1994003170A1 (no)

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CA2134211C (en) * 1992-05-11 1999-06-29 James K. Woodward Use of terfenadine derivatives as antihistaminics in a hepatically impaired patient
DK0701443T4 (da) 1992-08-03 2000-12-18 Sepracor Inc Terfenadinmetabolitter og deres optisk rene isomerer til behandling af allergiske lidelser
US20020007068A1 (en) 1999-07-16 2002-01-17 D'ambra Thomas E. Piperidine derivatives and process for their production
DK1369409T3 (da) * 1993-06-24 2006-08-14 Amr Technology Inc Fremgangsmåde til fremstilling af forbindelser, der er anvendelige som mellemprodukter
WO1995010278A1 (en) * 1993-10-15 1995-04-20 Hoechst Marion Roussel, Inc. Treatment of allergic disorders with terfenadine carboxylate
US20030045722A1 (en) * 1994-05-18 2003-03-06 Henton Daniel R. Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof
EP1178041A1 (en) 1994-05-18 2002-02-06 Aventis Pharmaceuticals Inc. Process for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives
US5455049A (en) * 1995-01-04 1995-10-03 Ascent Pharmaceuticals, Inc. Terfenadine oral powder
KR100405116B1 (ko) 1995-02-28 2004-02-05 아벤티스 파마슈티칼스 인크. 피페리디노알칸올화합물에대한약제학적조성물
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US5906747A (en) * 1995-11-13 1999-05-25 Biosepra Inc. Separation of molecules from dilute solutions using composite chromatography media having high dynamic sorptive capacity at high flow rates
US6486177B2 (en) 1995-12-04 2002-11-26 Celgene Corporation Methods for treatment of cognitive and menopausal disorders with D-threo methylphenidate
US5908850A (en) * 1995-12-04 1999-06-01 Celgene Corporation Method of treating attention deficit disorders with d-threo methylphenidate
US5733756A (en) * 1996-01-05 1998-03-31 Celgene Corporation Lactams and processes for stereoselective enrichment of lactams, amides, and esters
US5837284A (en) 1995-12-04 1998-11-17 Mehta; Atul M. Delivery of multiple doses of medications
US6355656B1 (en) 1995-12-04 2002-03-12 Celgene Corporation Phenidate drug formulations having diminished abuse potential
US5922736A (en) * 1995-12-04 1999-07-13 Celegene Corporation Chronic, bolus administration of D-threo methylphenidate
US6153754A (en) 1995-12-21 2000-11-28 Albany Molecular Research, Inc. Process for production of piperidine derivatives
US6201124B1 (en) 1995-12-21 2001-03-13 Albany Molecular Research, Inc. Process for production of piperidine derivatives
ES2124167B1 (es) * 1996-06-04 1999-09-16 Espanola Prod Quimicos Nuevos derivados del bencimidazol con actividad antihistaminica.
US5925761A (en) * 1997-02-04 1999-07-20 Sepracor Inc. Synthesis of terfenadine and derivatives
US6962997B1 (en) * 1997-05-22 2005-11-08 Celgene Corporation Process and intermediates for resolving piperidyl acetamide steroisomers
PT998272E (pt) * 1997-08-26 2003-09-30 Aventis Pharma Inc Composicao farmaceutica para combinacao do descongestionante piperidinoalcanol
US6194431B1 (en) * 1998-04-14 2001-02-27 Paul D. Rubin Methods and compositions using terfenadine metabolites in combination with leukotriene inhibitors
DE19913862C2 (de) * 1999-03-26 2003-04-10 Forschungszentrum Juelich Gmbh Verfahren zur biokatalysierten Umsetzung schlecht wasserlöslicher Substanzen
DE10007203A1 (de) * 2000-02-17 2001-08-23 Asta Medica Ag Neue Kombination nichtsedierender Antihistaminika mit Substanzen, die die Leukotrienwirkung beeinflussen, zur Behandlung der Rhinitis/Konjunktivitis
US6613907B2 (en) 2000-11-08 2003-09-02 Amr Technology, Inc. Process for the production of piperidine derivatives with microorganisms
AU2002305162A1 (en) * 2001-04-09 2002-10-21 Teva Pharmaceutical Industries Ltd. Polymorphs of fexofenadine hydrochloride
US20030021849A1 (en) * 2001-04-09 2003-01-30 Ben-Zion Dolitzky Polymorphs of fexofenadine hydrochloride
IL159266A0 (en) * 2001-06-18 2004-06-01 Reddys Lab Ltd Dr Crystalline forms of fexofenadine and processes for the preparation thereof
WO2003020274A1 (en) * 2001-08-30 2003-03-13 Aventis Pharmaceuticals Inc. Treatment of atopic dermatitis
AU2003248657A1 (en) * 2002-06-10 2003-12-22 Teva Pharmaceutical Industries Ltd. Polymorphic form xvi of fexofenadine hydrochloride
TWI326214B (en) * 2002-07-17 2010-06-21 Avanir Pharmaceuticals Inc Pharmaceutical compositions comprising dextromethorphan and quinidine for the treatment of neurological disorders
RU2238081C1 (ru) * 2003-07-14 2004-10-20 Открытое акционерное общество "Московская фармацевтическая фабрика" Средство антиконгестивного действия
US20050026890A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an antihistamine for treatment of asthma or chronic obstructive pulmonary disease
TW200517114A (en) 2003-10-15 2005-06-01 Combinatorx Inc Methods and reagents for the treatment of immunoinflammatory disorders
JP4515121B2 (ja) 2004-03-15 2010-07-28 東芝テック株式会社 ワイヤドットプリンタヘッド及びワイヤドットプリンタ
JP4473021B2 (ja) 2004-03-22 2010-06-02 東芝テック株式会社 窒化層形成方法、磁気回路形成部材、アーマチュア、ワイヤドットプリンタヘッド及びワイヤドットプリンタ
MXPA06012281A (es) * 2004-04-26 2007-07-18 Teva Pharma Formas cristalinas de clorhidrato de fexofenadina y procesos para su preparacion.
US20050239830A1 (en) * 2004-04-26 2005-10-27 Vikram Khetani Methods of diminishing co-abuse potential
US7498345B2 (en) 2004-09-17 2009-03-03 Albany Molecular Research, Inc. Process for production of piperidine derivatives
US7498443B2 (en) 2004-09-17 2009-03-03 Albany Molecular Research, Inc. Process for production of carebastine
JP2008514641A (ja) * 2004-09-28 2008-05-08 テバ ファーマシューティカル インダストリーズ リミティド 結晶形フェキソフェナジン、およびその調製方法
NZ555842A (en) * 2004-12-09 2010-10-29 Celgene Corp Treatment of various conditions of patients with Tourette syndrome, tics, or a family history thereof sing D-threo methylphenidate free from other isomers
EP2218442A1 (en) 2005-11-09 2010-08-18 CombinatoRx, Inc. Methods, compositions, and kits for the treatment of ophthalmic disorders
AU2008287285B2 (en) * 2007-04-13 2013-05-16 Southern Research Institute Anti-angiogenic agents and methods of use
US20090076080A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched fexofenadine
WO2014052836A2 (en) 2012-09-27 2014-04-03 Dunman Paul M Methods and compositions for treating infection
AU2016235484B2 (en) 2015-03-26 2021-02-18 Jacqueline M. Iversen Methods and compositions to inhibit symptoms associated with veisalgia
DE102017130361A1 (de) 2017-12-18 2019-07-04 Lsp Innovative Automotive Systems Gmbh Statorzahn und Stator mit guter elektrischer Isolierung und gleichzeitig sehr hoher Wärmeleitfähigkeit zur Leistungssteigerung von Elektromotoren

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US4254129A (en) † 1979-04-10 1981-03-03 Richardson-Merrell Inc. Piperidine derivatives
US4552899A (en) † 1984-04-09 1985-11-12 Analgesic Associates Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs
US4829064A (en) † 1987-06-08 1989-05-09 Analgesic Associates Cough/cold mixtures comprising non-sedating antihistamine drugs
US4996061A (en) † 1987-10-07 1991-02-26 Merrell Dow Pharmaceuticals Inc. Pharmaceutical composition for piperidinoalkanol-decongestant combination
US4929605A (en) * 1987-10-07 1990-05-29 Merrell Dow Pharmaceuticals Inc. Pharmaceutical composition for piperidinoalkanol derivatives
EP0635004B1 (en) * 1992-04-10 2002-07-17 Merrell Pharmaceuticals Inc. 4-diphenylmethyl piperidine derivatives and process for their preparation
CA2134211C (en) * 1992-05-11 1999-06-29 James K. Woodward Use of terfenadine derivatives as antihistaminics in a hepatically impaired patient
DK0701443T4 (da) * 1992-08-03 2000-12-18 Sepracor Inc Terfenadinmetabolitter og deres optisk rene isomerer til behandling af allergiske lidelser
DK1369409T3 (da) * 1993-06-24 2006-08-14 Amr Technology Inc Fremgangsmåde til fremstilling af forbindelser, der er anvendelige som mellemprodukter
EP0705245B1 (en) * 1993-06-25 2003-01-02 Merrell Pharmaceuticals Inc. Novel intermediates for the preparation of antihistaminic 4-diphenylmethyl/diphenylmethoxy piperidine derivatives
CA2128820A1 (en) * 1993-07-27 1995-01-28 Walter G. Gowan, Jr. Rapidly disintegrating pharmaceutical dosage form and process for preparation thereof
CA2128821A1 (en) * 1993-07-27 1995-01-28 Dilip J. Gole Freeze-dried pharmaceutical dosage form and process for separation thereof
WO1995010278A1 (en) * 1993-10-15 1995-04-20 Hoechst Marion Roussel, Inc. Treatment of allergic disorders with terfenadine carboxylate

Also Published As

Publication number Publication date
GR3026530T3 (en) 1998-07-31
GB2284351A (en) 1995-06-07
JP2000086513A (ja) 2000-03-28
AU4798693A (en) 1994-03-03
HU226242B1 (en) 2008-07-28
JP2000086514A (ja) 2000-03-28
GR960300024T1 (en) 1996-05-31
CA2141572A1 (en) 1994-02-17
DK0701443T4 (da) 2000-12-18
WO1994003170A1 (en) 1994-02-17
DK0815860T3 (da) 2006-08-14
NO310644B1 (no) 2001-08-06
JP2000086516A (ja) 2000-03-28
HK1045806B (en) 2008-03-14
DE69316660T2 (de) 1998-05-07
JP3288661B2 (ja) 2002-06-04
GB2284351B (en) 1996-11-27
RU95107881A (ru) 1996-11-27
FI950467A0 (fi) 1995-02-02
ES2284740T3 (es) 2007-11-16
RU2167657C2 (ru) 2001-05-27
AU675240B2 (en) 1997-01-30
EP1214937A3 (en) 2002-10-30
ATE162399T1 (de) 1998-02-15
ES2086270T3 (es) 1998-03-01
EP0815860B1 (en) 2006-04-12
HK1045806A1 (en) 2002-12-13
JP3041954B2 (ja) 2000-05-15
HUT71889A (en) 1996-02-28
ATE322899T1 (de) 2006-04-15
PL307339A1 (en) 1995-05-15
RO116043B1 (ro) 2000-10-30
JP3288662B2 (ja) 2002-06-04
SK12495A3 (en) 1997-01-08
EP0815860A2 (en) 1998-01-07
CZ27495A3 (en) 1996-09-11
FI950467A7 (fi) 1995-03-31
DE701443T1 (de) 1997-01-30
JP3288660B2 (ja) 2002-06-04
AU7182296A (en) 1997-01-30
PT1214937E (pt) 2007-07-25
DE69334145T2 (de) 2008-01-24
DK0701443T3 (da) 1998-02-09
PT815860E (pt) 2006-08-31
ES2086270T1 (es) 1996-07-01
ES2086270T5 (es) 2001-02-01
US5375693A (en) 1994-12-27
DE69334008T2 (de) 2006-10-19
EP1214937B1 (en) 2007-05-30
BR9306841A (pt) 1998-12-08
DE9320925U1 (de) 1995-08-31
GR3035417T3 (en) 2001-05-31
DE69316660D1 (de) 1998-02-26
NO950374L (no) 1995-03-29
JPH08500348A (ja) 1996-01-16
EP1214937A2 (en) 2002-06-19
CA2141572C (en) 2001-02-06
JP2000086515A (ja) 2000-03-28
EP0815860A3 (en) 1998-01-14
KR950702420A (ko) 1995-07-29
EP0701443B1 (en) 1998-01-21
PL174373B1 (pl) 1998-07-31
DE69334008D1 (de) 2006-05-24
HU9500313D0 (en) 1995-03-28
JP2000086512A (ja) 2000-03-28
ATE363283T1 (de) 2007-06-15
EP0701443B2 (en) 2000-11-22
DK1214937T3 (da) 2007-09-17
DE69334145D1 (de) 2007-07-12
FI950467L (fi) 1995-03-31
EP1688142A1 (en) 2006-08-09
EP0701443A1 (en) 1996-03-20
GB9502183D0 (en) 1995-03-22
JP3037697B2 (ja) 2000-04-24
ES2257757T3 (es) 2006-08-01
AU1842999A (en) 1999-04-29
DE69316660T3 (de) 2001-04-05

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