NO934792D0 - Xantinderivater - Google Patents
XantinderivaterInfo
- Publication number
- NO934792D0 NO934792D0 NO934792A NO934792A NO934792D0 NO 934792 D0 NO934792 D0 NO 934792D0 NO 934792 A NO934792 A NO 934792A NO 934792 A NO934792 A NO 934792A NO 934792 D0 NO934792 D0 NO 934792D0
- Authority
- NO
- Norway
- Prior art keywords
- lower alkyl
- independently represent
- chem
- represent hydrogen
- hydroxy
- Prior art date
Links
- LRFVTYWOQMYALW-UHFFFAOYSA-N 9H-xanthine Chemical class O=C1NC(=O)NC2=C1NC=N2 LRFVTYWOQMYALW-UHFFFAOYSA-N 0.000 title abstract 2
- 229940083747 low-ceiling diuretics xanthine derivative Drugs 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 229910052739 hydrogen Inorganic materials 0.000 abstract 6
- 239000001257 hydrogen Substances 0.000 abstract 6
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 150000002431 hydrogen Chemical class 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP34411692 | 1992-12-24 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO934792D0 true NO934792D0 (no) | 1993-12-23 |
| NO934792L NO934792L (no) | 1994-06-27 |
| NO300925B1 NO300925B1 (no) | 1997-08-18 |
Family
ID=18366763
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO934792A NO300925B1 (no) | 1992-12-24 | 1993-12-23 | Xantinderivater |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5670498A (no) |
| EP (1) | EP0607607B1 (no) |
| AT (1) | ATE143019T1 (no) |
| CA (1) | CA2112031A1 (no) |
| DE (1) | DE69304883T2 (no) |
| NO (1) | NO300925B1 (no) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE218139T1 (de) * | 1994-02-23 | 2002-06-15 | Kyowa Hakko Kogyo Kk | Xanthin-derivate |
| WO1999012546A1 (en) * | 1997-09-05 | 1999-03-18 | Kyowa Hakko Kogyo Co., Ltd. | Remedial agent for neural degeneration |
| US6403567B1 (en) * | 1999-06-22 | 2002-06-11 | Cv Therapeutics, Inc. | N-pyrazole A2A adenosine receptor agonists |
| USRE47351E1 (en) | 1999-06-22 | 2019-04-16 | Gilead Sciences, Inc. | 2-(N-pyrazolo)adenosines with application as adenosine A2A receptor agonists |
| US6815446B1 (en) | 1999-08-31 | 2004-11-09 | Vanderbilt University | Selective antagonists of A2B adenosine receptors |
| AU7962000A (en) * | 1999-10-29 | 2001-05-14 | Kyowa Hakko Kogyo Co. Ltd. | Us0027324for eating disorders |
| CA2671940A1 (en) | 2000-02-23 | 2001-08-30 | Cv Therapeutics, Inc. | Identification of partial agonists of the a2a adenosine receptor |
| US20050020915A1 (en) * | 2002-07-29 | 2005-01-27 | Cv Therapeutics, Inc. | Myocardial perfusion imaging methods and compositions |
| KR20050026546A (ko) * | 2002-07-29 | 2005-03-15 | 씨브이 쎄러퓨틱스, 인코포레이티드 | Ａ2ａ 수용체 작용제를 이용한 심근 관류 조영 |
| US8470801B2 (en) | 2002-07-29 | 2013-06-25 | Gilead Sciences, Inc. | Myocardial perfusion imaging methods and compositions |
| US7148229B2 (en) * | 2003-02-19 | 2006-12-12 | Hoffman-La Roche Inc. | Sulfonamide substituted xanthine derivatives |
| TWI346114B (en) * | 2003-09-29 | 2011-08-01 | Method for stabilization of diarylvinylene compounds | |
| US7763625B2 (en) * | 2004-01-28 | 2010-07-27 | Kyowa Hakko Kirin Co., Ltd. | Agents for treating migraine |
| WO2006044856A2 (en) | 2004-10-20 | 2006-04-27 | Cv Therapeuitics, Inc. | Use of a2a adenosine receptor agonists |
| KR101494125B1 (ko) * | 2006-02-03 | 2015-02-16 | 길리애드 사이언시즈, 인코포레이티드 | Ａ2ａ-아데노신 수용체 효능제 및 이의 다형체의 제조 방법 |
| CA2662278C (en) * | 2006-09-01 | 2011-11-22 | Cv Therapeutics, Inc. | Methods and compositions for increasing patient tolerability during myocardial imaging methods |
| US20090081120A1 (en) * | 2006-09-01 | 2009-03-26 | Cv Therapeutics, Inc. | Methods and Compositions for Increasing Patient Tolerability During Myocardial Imaging Methods |
| JP2011502101A (ja) * | 2006-09-29 | 2011-01-20 | ギリアード・パロ・アルト・インコーポレイテッド | 肺疾患の病歴を有する患者における心筋画像化法 |
| US20080267861A1 (en) * | 2007-01-03 | 2008-10-30 | Cv Therapeutics, Inc. | Myocardial Perfusion Imaging |
| US8871751B2 (en) * | 2008-01-18 | 2014-10-28 | The Board Of Trustees Of The University Of Illinois | Compositions and methods relating to nuclear hormone and steroid hormone receptors including inhibitors of estrogen receptor alpha-mediated gene expression and inhibition of breast cancer |
| MX2011003168A (es) * | 2008-09-29 | 2011-05-19 | Gilead Sciences Inc | Combinaciones de un agente de control de cantidad y un antagonista del receptor a-2-alfa para utilizarse en metodos de tomografia computarizada de detectores multiples. |
| CN110981876B (zh) * | 2018-12-21 | 2021-10-01 | 广东东阳光药业有限公司 | 8-取代的苯乙烯基黄嘌呤衍生物及其用途 |
| US20220202822A1 (en) * | 2019-04-24 | 2022-06-30 | Sunshine Lake Pharma Co., Ltd. | 8-substituted aryl vinyl xanthine derivatives and uses thereof |
| CN111018856B (zh) * | 2019-12-12 | 2021-10-01 | 广东东阳光药业有限公司 | 8-取代的苯乙烯基黄嘌呤衍生物及其用途 |
| CN111072663B (zh) * | 2019-12-12 | 2021-10-01 | 广东东阳光药业有限公司 | 8-取代的苯乙烯基黄嘌呤衍生物及其用途 |
| CA3170917A1 (en) * | 2020-03-10 | 2021-09-16 | Mark Williams | Purine compounds for treating disorders |
| CN113248505B (zh) * | 2021-06-09 | 2021-09-21 | 南京安杰新生物医药有限公司 | 伊曲茶碱去甲基杂质的制备方法 |
| US20250353849A1 (en) * | 2021-12-03 | 2025-11-20 | Marvel Biotechnology | Purine compounds for treating disorders |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4452788A (en) * | 1982-04-21 | 1984-06-05 | Warner-Lambert Company | Substituted 8-phenylxanthines |
| GB8510758D0 (en) * | 1985-04-27 | 1985-06-05 | Wellcome Found | Compounds |
| EP0423805B1 (en) * | 1989-10-20 | 2000-08-23 | Kyowa Hakko Kogyo Kabushiki Kaisha | Condensed purine derivatives |
| ATE176470T1 (de) * | 1990-10-18 | 1999-02-15 | Kyowa Hakko Kogyo Kk | Xanthinderivate |
-
1993
- 1993-12-21 CA CA002112031A patent/CA2112031A1/en not_active Abandoned
- 1993-12-23 AT AT93120842T patent/ATE143019T1/de not_active IP Right Cessation
- 1993-12-23 EP EP93120842A patent/EP0607607B1/en not_active Expired - Lifetime
- 1993-12-23 NO NO934792A patent/NO300925B1/no not_active IP Right Cessation
- 1993-12-23 DE DE69304883T patent/DE69304883T2/de not_active Expired - Fee Related
-
1995
- 1995-09-13 US US08/527,497 patent/US5670498A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69304883T2 (de) | 1997-05-15 |
| NO934792L (no) | 1994-06-27 |
| CA2112031A1 (en) | 1994-06-25 |
| ATE143019T1 (de) | 1996-10-15 |
| US5670498A (en) | 1997-09-23 |
| EP0607607A1 (en) | 1994-07-27 |
| DE69304883D1 (de) | 1996-10-24 |
| NO300925B1 (no) | 1997-08-18 |
| EP0607607B1 (en) | 1996-09-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |