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DK0695755T3 - Pyrrolocarbazoler - Google Patents

Pyrrolocarbazoler

Info

Publication number
DK0695755T3
DK0695755T3 DK95111472T DK95111472T DK0695755T3 DK 0695755 T3 DK0695755 T3 DK 0695755T3 DK 95111472 T DK95111472 T DK 95111472T DK 95111472 T DK95111472 T DK 95111472T DK 0695755 T3 DK0695755 T3 DK 0695755T3
Authority
DK
Denmark
Prior art keywords
lower alkyl
pyrrolocarbazoles
hydrogen
heteroaryl
chem
Prior art date
Application number
DK95111472T
Other languages
English (en)
Inventor
Chris Allen Broka
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK0695755T3 publication Critical patent/DK0695755T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06Peri-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK95111472T 1994-08-04 1995-07-21 Pyrrolocarbazoler DK0695755T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28604394A 1994-08-04 1994-08-04

Publications (1)

Publication Number Publication Date
DK0695755T3 true DK0695755T3 (da) 1999-06-28

Family

ID=23096813

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95111472T DK0695755T3 (da) 1994-08-04 1995-07-21 Pyrrolocarbazoler

Country Status (29)

Country Link
US (1) US5721267A (da)
EP (1) EP0695755B1 (da)
JP (1) JP2672290B2 (da)
KR (1) KR100326790B1 (da)
CN (1) CN1051551C (da)
AT (1) ATE172463T1 (da)
AU (1) AU692563B2 (da)
BR (1) BR9503536A (da)
CA (1) CA2155148A1 (da)
CO (1) CO4410329A1 (da)
CZ (1) CZ288583B6 (da)
DE (1) DE69505470T2 (da)
DK (1) DK0695755T3 (da)
ES (1) ES2123873T3 (da)
FI (1) FI111258B (da)
HU (1) HU225567B1 (da)
IL (1) IL114785A (da)
MA (1) MA23639A1 (da)
MY (1) MY117092A (da)
NO (1) NO304833B1 (da)
NZ (1) NZ272687A (da)
PE (1) PE34996A1 (da)
PL (1) PL180801B1 (da)
RU (1) RU2162089C2 (da)
SA (1) SA95160203B1 (da)
TR (1) TR199500954A1 (da)
TW (1) TW403652B (da)
UY (1) UY24010A1 (da)
ZA (1) ZA956327B (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1283203B1 (it) * 1996-03-07 1998-04-16 Ausimont Spa Composizioni estinguenti la fiamma
US6020298A (en) * 1997-03-05 2000-02-01 Ausimont S.P.A. Solvent cleaning agents including additives of the formula Rf -CFX-L containing perfluoroalkylenic units
DE19744257B4 (de) * 1997-10-07 2004-04-15 Zentaris Gmbh Beta-Carboline und deren Verwendung zur Behandlung von malignen und anderen, auf pathologischen Zellproliferationen beruhenden Erkrankungen
US7122679B2 (en) * 2000-05-09 2006-10-17 Cephalon, Inc. Multicyclic compounds and the use thereof
WO2003051883A1 (en) * 2001-12-18 2003-06-26 Kyowa Hakko Kogyo Co., Ltd. Indole derivative
CA2483496A1 (en) * 2002-04-26 2003-11-06 Warner-Lambert Company Llc Inhibitors of checkpoint kinases (wee1 and chk1)
US7094798B1 (en) 2002-04-26 2006-08-22 Pfizer Inc Inhibitors of checkpoint kinases (Wee1 and Chk1)
JP2012051804A (ja) * 2008-12-26 2012-03-15 Kyoto Univ Eg5阻害剤
RU2404983C1 (ru) * 2009-06-08 2010-11-27 Федеральное Государственное Образовательное Учреждение Высшего Профессионального Образования "Южный Федеральный Университет" СПОСОБ ПОЛУЧЕНИЯ 2-R1-6-R2-5-АРИЛ-ПИРРОЛО[3,4-с]КАРБАЗОЛ-1,3(2Н,6Н)-ДИОНОВ
AU2010259588B2 (en) * 2009-06-10 2015-05-28 Chugai Seiyaku Kabushiki Kaisha Tetracyclic compound
CA2808210C (en) 2010-08-20 2019-10-01 Chugai Seiyaku Kabushiki Kaisha Tetracyclic compounds having alk inhibitory activity and compositions thereof
RU2648818C2 (ru) 2012-09-25 2018-03-28 Чугаи Сейяку Кабусики Кайся Ингибитор ret
KR101577098B1 (ko) 2012-11-20 2015-12-14 주식회사 두산 유기 화합물 및 이를 포함하는 유기 전계 발광 소자
US10350214B2 (en) 2014-04-25 2019-07-16 Chugai Seiyaku Kabushiki Kaisha Preparation containing tetracyclic compound at high dose
RU2016146119A (ru) 2014-04-25 2018-05-29 Чугаи Сейяку Кабусики Кайся Новый кристалл тетрациклического соединения
TWI718102B (zh) 2014-08-08 2021-02-11 日商中外製藥股份有限公司 4環性化合物的非晶質體
AU2016207431B2 (en) 2015-01-16 2021-05-06 Chugai Seiyaku Kabushiki Kaisha Combination drug
JP7167171B2 (ja) 2018-09-04 2022-11-08 中外製薬株式会社 4環性化合物の製造方法
KR102509614B1 (ko) * 2022-08-09 2023-03-13 김학수 부직포 패널 제조방법 및 제조장치

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8611762D0 (en) * 1986-05-14 1986-06-25 Wellcome Found Polycyclic biocidal compounds
US4785085A (en) * 1986-11-21 1988-11-15 Bristol-Myers Company Rebeccamycin analogs
NZ227850A (en) * 1988-02-10 1991-11-26 Hoffmann La Roche Indole substituted pyrrole derivatives; preparatory process and medicaments for use against inflammatory immunological, bronchopulmonary or vascular disorders
DE3833008A1 (de) * 1988-09-29 1990-04-05 Goedecke Ag Pyrrolocarbozol-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel
MC2096A1 (fr) * 1989-02-23 1991-02-15 Hoffmann La Roche Pyrroles substitues
US5166204A (en) * 1989-11-01 1992-11-24 Toyama Chemical Co., Ltd. Isoindole derivatives and salts thereof and antitumor agent comprising the same
DE4005969A1 (de) * 1990-02-26 1991-08-29 Boehringer Mannheim Gmbh Neue trisubstituierte pyrrole, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
DE4217964A1 (de) * 1992-05-30 1993-12-02 Goedecke Ag Indolocarbazol-Imide und deren Verwendung
AU678435B2 (en) * 1993-05-10 1997-05-29 F. Hoffmann-La Roche Ag Substituted pyrroles
DE69409641T2 (de) * 1993-05-28 1998-11-26 Cephalon, Inc., West Chester, Pa. Anwendung von indolocarbazol-derivaten zur behandlung von prostataerkrankungen

Also Published As

Publication number Publication date
EP0695755B1 (en) 1998-10-21
IL114785A0 (en) 1995-11-27
CO4410329A1 (es) 1997-01-09
HU9502270D0 (en) 1995-09-28
KR960007592A (ko) 1996-03-22
AU692563B2 (en) 1998-06-11
ES2123873T3 (es) 1999-01-16
NO953052D0 (no) 1995-08-03
FI111258B (fi) 2003-06-30
TR199500954A1 (tr) 1996-10-21
SA95160203B1 (ar) 2005-07-31
PE34996A1 (es) 1996-10-01
AU2722095A (en) 1996-02-15
CZ199795A3 (en) 1996-02-14
CA2155148A1 (en) 1996-02-05
HK1012341A1 (en) 1999-07-30
CZ288583B6 (cs) 2001-07-11
KR100326790B1 (ko) 2002-07-27
NO953052L (no) 1996-02-05
US5721267A (en) 1998-02-24
IL114785A (en) 1998-06-15
ZA956327B (en) 1996-02-04
RU2162089C2 (ru) 2001-01-20
PL309874A1 (en) 1996-02-05
DE69505470T2 (de) 1999-05-12
HUT73437A (en) 1996-07-29
MY117092A (en) 2004-05-31
JPH0859666A (ja) 1996-03-05
DE69505470D1 (de) 1998-11-26
MA23639A1 (fr) 1996-04-01
EP0695755A1 (en) 1996-02-07
NZ272687A (en) 1997-04-24
FI953710L (fi) 1996-02-05
BR9503536A (pt) 1996-06-04
FI953710A0 (fi) 1995-08-03
CN1123280A (zh) 1996-05-29
HU225567B1 (en) 2007-03-28
ATE172463T1 (de) 1998-11-15
UY24010A1 (es) 2000-12-29
TW403652B (en) 2000-09-01
CN1051551C (zh) 2000-04-19
NO304833B1 (no) 1999-02-22
JP2672290B2 (ja) 1997-11-05
PL180801B1 (pl) 2001-04-30

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