NO934700L - Abrin varianter, abrin immunotoksiner og farmasoeytiske blandinger inneholdende disse - Google Patents
Abrin varianter, abrin immunotoksiner og farmasoeytiske blandinger inneholdende disseInfo
- Publication number
- NO934700L NO934700L NO934700A NO934700A NO934700L NO 934700 L NO934700 L NO 934700L NO 934700 A NO934700 A NO 934700A NO 934700 A NO934700 A NO 934700A NO 934700 L NO934700 L NO 934700L
- Authority
- NO
- Norway
- Prior art keywords
- abrin
- immunotoxins
- variants
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
- 108010066676 Abrin Proteins 0.000 title abstract 3
- 239000002596 immunotoxin Substances 0.000 title abstract 3
- 231100000608 immunotoxin Toxicity 0.000 title abstract 3
- 229940051026 immunotoxin Drugs 0.000 title abstract 3
- 230000002637 immunotoxin Effects 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 229930186900 holotoxin Natural products 0.000 abstract 2
- 108090001090 Lectins Proteins 0.000 abstract 1
- 102000004856 Lectins Human genes 0.000 abstract 1
- 231100000742 Plant toxin Toxicity 0.000 abstract 1
- 230000027455 binding Effects 0.000 abstract 1
- 239000002523 lectin Substances 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 239000003123 plant toxin Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
- C07K14/42—Lectins, e.g. concanavalin, phytohaemagglutinin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
- A61K47/6817—Toxins
- A61K47/6819—Plant toxins
- A61K47/6821—Plant heterodimeric toxins, e.g. abrin or modeccin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
- A61K47/6817—Toxins
- A61K47/6819—Plant toxins
- A61K47/6825—Ribosomal inhibitory proteins, i.e. RIP-I or RIP-II, e.g. Pap, gelonin or dianthin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Chemical & Material Sciences (AREA)
- Botany (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919113475A GB9113475D0 (en) | 1991-06-21 | 1991-06-21 | Chemical compound |
| PCT/EP1992/001419 WO1993000367A1 (fr) | 1991-06-21 | 1992-06-20 | Variantes d'abrine et immunotoxines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO934700D0 NO934700D0 (no) | 1993-12-20 |
| NO934700L true NO934700L (no) | 1993-12-20 |
Family
ID=10697123
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO934700A NO934700L (no) | 1991-06-21 | 1993-12-20 | Abrin varianter, abrin immunotoksiner og farmasoeytiske blandinger inneholdende disse |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0590011A1 (fr) |
| JP (1) | JPH06510525A (fr) |
| GB (1) | GB9113475D0 (fr) |
| NO (1) | NO934700L (fr) |
| WO (1) | WO1993000367A1 (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994002174A1 (fr) * | 1992-07-28 | 1994-02-03 | Toray Industries, Inc. | Immunocomplexe |
| KR20090073255A (ko) * | 2006-10-27 | 2009-07-02 | 트르스티스 오브 보스톤 유니버시티 | 질병, 악성 종양 및 장애를 치료하기 위한 표적화 분열 생체 분자성 접합체, 및 그의 생성 방법 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2575160B1 (fr) * | 1984-12-21 | 1987-03-20 | Sanofi Sa | Composes ionophores carboxyliques monovalents |
| JPH02502251A (ja) * | 1987-11-13 | 1990-07-26 | ヘルマン カーティンガー | ヒトのモノクローン性抗hiv‐1‐抗体 |
-
1991
- 1991-06-21 GB GB919113475A patent/GB9113475D0/en active Pending
-
1992
- 1992-06-20 JP JP5501328A patent/JPH06510525A/ja active Pending
- 1992-06-20 WO PCT/EP1992/001419 patent/WO1993000367A1/fr not_active Ceased
- 1992-06-20 EP EP92913131A patent/EP0590011A1/fr not_active Withdrawn
-
1993
- 1993-12-20 NO NO934700A patent/NO934700L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0590011A1 (fr) | 1994-04-06 |
| NO934700D0 (no) | 1993-12-20 |
| WO1993000367A1 (fr) | 1993-01-07 |
| GB9113475D0 (en) | 1991-08-07 |
| JPH06510525A (ja) | 1994-11-24 |
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