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NO934566L - Imidazole derivatives, process for their preparation and pharmaceutical preparation thereof - Google Patents

Imidazole derivatives, process for their preparation and pharmaceutical preparation thereof

Info

Publication number
NO934566L
NO934566L NO934566A NO934566A NO934566L NO 934566 L NO934566 L NO 934566L NO 934566 A NO934566 A NO 934566A NO 934566 A NO934566 A NO 934566A NO 934566 L NO934566 L NO 934566L
Authority
NO
Norway
Prior art keywords
preparation
alkyl group
imidazole derivatives
derivatives
branched
Prior art date
Application number
NO934566A
Other languages
Norwegian (no)
Other versions
NO934566D0 (en
Inventor
Gerard Cremer
Jean-Claude Muller
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of NO934566D0 publication Critical patent/NO934566D0/en
Publication of NO934566L publication Critical patent/NO934566L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

3-(kinolin-6-yl-metyl)-4H-imidazol-4-on-derivater med formelen (I) hvor R1 er en rettkjedet eller forgrenet (C2-CS)alkylgruppe, R2 eller R3 er, uavhengig av hverandre, enten et hydrogenatom eller en rettkjedet eller forgrenet (C^-Cj)alkylgruppe eller en (CH2)n-arylgruppe hvor n = O til 3, eller R2 og R3 kan sammen med imidazolringen danne en spirocyklo(C3-C8)alkyl- gruppe, såvel som deres addisjonssalter med farmasøytisk tålbare syrer og baser. Derivatene har terapautisk anvendelse.3- (quinolin-6-yl-methyl) -4H-imidazol-4-one derivatives of formula (I) wherein R 1 is a straight-chain or branched (C 2 -C 6) alkyl group, R 2 or R 3 are, independently of each other, either a hydrogen atom or a straight chain or branched (C 1 -C 2) alkyl group or a (CH 2) n-aryl group where n = O to 3, or R 2 and R 3 can together with the imidazole ring form a spirocyclo (C 3 -C 8) alkyl group, as well as their addition salts with pharmaceutically tolerable acids and bases. The derivatives have therapeutic application.

NO934566A 1992-12-14 1993-12-13 Imidazole derivatives, process for their preparation and pharmaceutical preparation thereof NO934566L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9215038A FR2699174B1 (en) 1992-12-14 1992-12-14 Derivatives of 3- (quinoline-6-yl-methyl) -4H-imidazol-4-one, their preparation and their therapeutic use.

Publications (2)

Publication Number Publication Date
NO934566D0 NO934566D0 (en) 1993-12-13
NO934566L true NO934566L (en) 1994-06-15

Family

ID=9436560

Family Applications (1)

Application Number Title Priority Date Filing Date
NO934566A NO934566L (en) 1992-12-14 1993-12-13 Imidazole derivatives, process for their preparation and pharmaceutical preparation thereof

Country Status (17)

Country Link
EP (1) EP0604259A1 (en)
JP (1) JP2548511B2 (en)
KR (1) KR940014386A (en)
CN (1) CN1095378A (en)
AU (1) AU5233893A (en)
CA (1) CA2111302A1 (en)
CZ (1) CZ273293A3 (en)
FI (1) FI935575A7 (en)
FR (1) FR2699174B1 (en)
HU (1) HUT69701A (en)
IL (1) IL108011A0 (en)
MX (1) MX9307834A (en)
NO (1) NO934566L (en)
NZ (1) NZ250441A (en)
PL (1) PL301461A1 (en)
SK (1) SK141193A3 (en)
ZA (1) ZA939333B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2716196B1 (en) * 1994-02-16 1996-04-05 Synthelabo 8- [2- (1H-tetrazol-5-yl) phenyl] quinoline derivatives, their preparation and their therapeutic use.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2683819B1 (en) * 1991-10-28 1994-02-11 Synthelabo QUINOLEIN DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR THERAPEUTIC APPLICATION.
US5478832A (en) * 1992-05-08 1995-12-26 The Green Cross Corporation Quinoline compounds

Also Published As

Publication number Publication date
KR940014386A (en) 1994-07-18
NO934566D0 (en) 1993-12-13
FR2699174A1 (en) 1994-06-17
FI935575A0 (en) 1993-12-13
MX9307834A (en) 1995-01-31
ZA939333B (en) 1994-08-25
EP0604259A1 (en) 1994-06-29
FI935575L (en) 1994-06-15
IL108011A0 (en) 1994-04-12
CZ273293A3 (en) 1994-07-13
PL301461A1 (en) 1994-06-27
NZ250441A (en) 1995-04-27
AU5233893A (en) 1994-06-23
CN1095378A (en) 1994-11-23
FR2699174B1 (en) 1995-01-20
CA2111302A1 (en) 1994-06-15
JP2548511B2 (en) 1996-10-30
HUT69701A (en) 1995-09-28
JPH06199841A (en) 1994-07-19
HU9303560D0 (en) 1994-04-28
FI935575A7 (en) 1994-06-15
SK141193A3 (en) 1995-02-08

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