[go: up one dir, main page]

NO934300D0 - Pyrrolidin- og tiazolidinderivater, deres fremstilling samt medikamenter inneholdende forbindelsene - Google Patents

Pyrrolidin- og tiazolidinderivater, deres fremstilling samt medikamenter inneholdende forbindelsene

Info

Publication number
NO934300D0
NO934300D0 NO934300A NO934300A NO934300D0 NO 934300 D0 NO934300 D0 NO 934300D0 NO 934300 A NO934300 A NO 934300A NO 934300 A NO934300 A NO 934300A NO 934300 D0 NO934300 D0 NO 934300D0
Authority
NO
Norway
Prior art keywords
compounds
preparation
pyrrolidine
medicaments containing
thiazolidine derivatives
Prior art date
Application number
NO934300A
Other languages
English (en)
Other versions
NO180166C (no
NO934300L (no
NO180166B (no
Inventor
Marc Capet
Claude Cotrell
Claude Guyon
Michel Joannic
Franco Manfre
Gerard Roussel
Marie-Christine Du-Broeucq
Michel Cheve
Gilles Dutruc-Rosset
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of NO934300D0 publication Critical patent/NO934300D0/no
Publication of NO934300L publication Critical patent/NO934300L/no
Publication of NO180166B publication Critical patent/NO180166B/no
Publication of NO180166C publication Critical patent/NO180166C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Analytical Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO934300A 1991-07-10 1993-11-26 Pyrrolidin- og tiazolidinderivater samt medikamenter inneholdende forbindelsene NO180166C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9108675A FR2678938B1 (fr) 1991-07-10 1991-07-10 Derives de pyrrolidine, leur preparation et les medicaments les contenant.
PCT/FR1992/000626 WO1993001167A1 (fr) 1991-07-10 1992-07-03 Derives de pyrrolidine et thiazolidine, leur preparation et les medicaments les contenant

Publications (4)

Publication Number Publication Date
NO934300D0 true NO934300D0 (no) 1993-11-26
NO934300L NO934300L (no) 1993-11-26
NO180166B NO180166B (no) 1996-11-18
NO180166C NO180166C (no) 1997-02-26

Family

ID=9414933

Family Applications (1)

Application Number Title Priority Date Filing Date
NO934300A NO180166C (no) 1991-07-10 1993-11-26 Pyrrolidin- og tiazolidinderivater samt medikamenter inneholdende forbindelsene

Country Status (23)

Country Link
US (1) US5610144A (no)
EP (2) EP0593639B1 (no)
JP (1) JP3034043B2 (no)
KR (1) KR100234927B1 (no)
AT (1) ATE120732T1 (no)
AU (1) AU662345B2 (no)
BR (1) BR1100717A (no)
CA (1) CA2102697C (no)
CZ (1) CZ283602B6 (no)
DE (1) DE69201956T2 (no)
DK (1) DK0593639T3 (no)
ES (1) ES2071510T3 (no)
FI (1) FI105190B (no)
FR (1) FR2678938B1 (no)
HU (1) HU223470B1 (no)
IE (1) IE66331B1 (no)
NO (1) NO180166C (no)
NZ (1) NZ243514A (no)
PL (5) PL171054B1 (no)
RU (1) RU2118316C1 (no)
SK (1) SK1694A3 (no)
WO (1) WO1993001167A1 (no)
ZA (1) ZA925128B (no)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2695641B1 (fr) * 1992-09-11 1994-11-25 Rhone Poulenc Rorer Sa (Amino-3 phényl)-1 éthanesulfonate d'hydroquinine optiquement actif, sa préparation et son utilisation.
FR2700167B1 (fr) * 1993-01-07 1995-02-03 Rhone Poulenc Rorer Sa Dérivés de pyrrolidine et thiazolidine, leur préparation et les médicaments les contenant.
FR2700168B1 (fr) * 1993-01-07 1995-02-03 Rhone Poulenc Rorer Sa Dérivés de thiazolidine, leur préparation et les médicaments les contenant.
FR2700166B1 (fr) * 1993-01-07 1995-02-17 Rhone Poulenc Rorer Sa Dérivés de pyrrolidine, leur préparation et les médicaments les contenant.
FR2700165B1 (fr) * 1993-01-07 1995-02-17 Rhone Poulenc Rorer Sa Dérivés de pyrrolidine, leur préparation et les médicaments les contenant.
US5744485A (en) * 1994-03-25 1998-04-28 Vertex Pharmaceuticals Incorporated Carbamates and ureas as modifiers of multi-drug resistance
FR2721314B1 (fr) * 1994-06-20 1996-07-19 Rhone Poulenc Rorer Sa Dérivés de pyrrolidine, leur préparation et les médicaments les contenant.
FR2721608B1 (fr) * 1994-06-22 1996-07-19 Rhone Poulenc Rorer Sa Dérivés de thiazolidine, leur préparation et les médicaments les contenant.
FR2734724B1 (fr) * 1995-06-01 1997-07-04 Rhone Poulenc Rorer Sa Application de derives de pyrrolidine a la preparation de medicaments destines au traitement de l'alcoolisme
ATE205477T1 (de) 1995-06-06 2001-09-15 Pfizer Substituierte n-(indol-2-carbonyl)-amide und derivate als glycogen phosphorylase inhibitoren
KR100241643B1 (ko) * 1995-06-06 2000-03-02 디. 제이. 우드 당뇨병치료제인 치환된 N-(인돌-2-카르보닐)-β-알라님아미드 및 그의 유도체
FR2744361B1 (fr) * 1996-02-07 1998-02-27 Rhone Poulenc Rorer Sa Application de derives de pyrrolidine a la preparation de medicaments destines au traitement de l'abus de drogues ou de substances donnant lieu a des pharmacomanies ou a un usage excessif
TW442449B (en) 1996-07-04 2001-06-23 Hoechst Ag Process for preparing 1,2-dichloroethane by direct chlorination
IT1300055B1 (it) * 1998-04-17 2000-04-05 Boehringer Ingelheim Italia Eterocicli con anello a 5 termini difenil-sostituiti loro procedimento di preparazione e loro impiego come farmici
YU26700A (sh) * 1999-05-24 2002-06-19 Pfizer Products Inc. Postupak za cis-1-(2-(4-(6-metoksi-2-fenil-1,2,3,4- tetrahidronaftalen-1-il)fenoksi)etil)pirolidin
AU2001268607A1 (en) 2000-06-21 2002-01-02 Bristol-Myers Squibb Company Piperidine amides as modulators of chemokine receptor activity
US6277877B1 (en) * 2000-08-15 2001-08-21 Pfizer, Inc. Substituted n-(indole-2-carbonyl)glycinamides and derivates as glycogen phosphorylase inhibitors
CN101307046B (zh) * 2000-10-30 2012-08-15 詹森药业有限公司 三肽酶抑制剂
US7105556B2 (en) 2001-05-30 2006-09-12 Bristol-Myers Squibb Company Conformationally constrained analogs useful as antidiabetic and antiobesity agents and method
WO2004026822A2 (en) * 2002-09-19 2004-04-01 Abbott Laboratories Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-iv (dpp-iv)
US7238724B2 (en) 2002-09-19 2007-07-03 Abbott Laboratories Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV)
US7262207B2 (en) 2002-09-19 2007-08-28 Abbott Laboratories Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV)
US6846836B2 (en) 2003-04-18 2005-01-25 Bristol-Myers Squibb Company N-substituted phenylurea inhibitors of mitochondrial F1F0 ATP hydrolase
US7230002B2 (en) 2004-02-03 2007-06-12 Glenmark Pharmaceuticals Ltd. Dipeptidyl peptidase IV inhibitors; processes for their preparation and compositions thereof
JP2007522247A (ja) * 2004-02-11 2007-08-09 ザ オハイオ ステート ユニバーシティー リサーチ ファウンデーション 細胞増殖の阻害を示すアナログ、それを作製する方法およびその使用
WO2007086584A1 (ja) * 2006-01-30 2007-08-02 Meiji Seika Kaisha, Ltd. 新規ＦａｂＫおよびＦａｂＩ／Ｋ阻害剤
WO2008011499A1 (en) * 2006-07-20 2008-01-24 Abbott Laboratories Synthesis of (2s,5r)-5-ethynyl-1-{n-(4-methyl-1-(4-carboxy-pyridin-2-yl)piperidin-4-yl)glycyl}pyrrolidine-2-carbonitrile
US8247438B2 (en) 2008-02-27 2012-08-21 Neuropill, Inc. Methods for treating schizophrenia
CN101407502B (zh) * 2008-11-21 2010-12-22 南京大学 一类n-(叔丁氧基羰基)噻唑烷酸类化合物及其制法和用途
DE102009004204A1 (de) * 2009-01-09 2010-07-15 Christian-Albrechts-Universität Zu Kiel Verfahren zur verbesserten Bioaktivierung von Arzneistoffen
SI2513053T1 (en) * 2009-12-18 2018-02-28 Ogeda Sa Pyrrolidine carboxylic acid derivatives as G-protein-coupled receptor 43 agonists (GPR43), pharmaceutical composition and methods for use in the treatment of metabolic disorders
US9249181B2 (en) 2010-09-13 2016-02-02 Amylin Pharmaceuticals, Llc C-terminal amidation of polypeptides
MX2016006975A (es) 2013-11-27 2016-10-12 Euroscreen Sa Compuestos, composicion farmaceutica y metodos para su uso en el tratamiento de enfermedades inflamatorias.
CN107430127B (zh) 2015-01-24 2020-08-28 中央研究院 癌症标记及其使用方法
CN115768747A (zh) * 2020-06-10 2023-03-07 艾匹克治疗公司 (2s,5r)-5-(2-氯苯基)-1-(2′-甲氧基-[1,1′-联苯基]-4-羰基)吡咯烷-2-羧酸的合成

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH362072A (de) * 1957-03-19 1962-05-31 Ciba Geigy Verfahren zur Herstellung neuer Acylpiperidine
US4499102A (en) * 1979-12-13 1985-02-12 Santen Pharmaceutical Co., Ltd. Thiazolidine and pyrrolidine compounds and pharmaceutical compositions containing them
DE3272505D1 (en) * 1981-03-09 1986-09-18 Merck & Co Inc Substituted thiazolidine carboxylic acid analogs and derivatives as antihypertensives
DE3332633A1 (de) * 1983-09-09 1985-04-04 Luitpold-Werk Chemisch-pharmazeutische Fabrik GmbH & Co, 8000 München Substituierte carbonsaeurederivate, verfahren zu ihrer herstellung, und arzneimittel
AU629376B2 (en) * 1989-08-04 1992-10-01 Mitsubishi Chemical Corporation 1-phenylalkyl-3-phenylurea derivatives
US5258405A (en) * 1990-03-12 1993-11-02 Yamanouchi Pharmaceutical Co., Ltd. Urea derivatives and salts thereof in method for inhibiting the ACAT enzyme

Also Published As

Publication number Publication date
FI940072A0 (fi) 1994-01-07
ATE120732T1 (de) 1995-04-15
AU662345B2 (en) 1995-08-31
FR2678938A1 (fr) 1993-01-15
FI940072L (fi) 1994-01-07
CZ4994A3 (en) 1994-04-13
US5610144A (en) 1997-03-11
FI105190B (fi) 2000-06-30
IE66331B1 (en) 1995-12-27
DE69201956D1 (de) 1995-05-11
NO180166C (no) 1997-02-26
PL171094B1 (pl) 1997-03-28
BR1100717A (pt) 2000-03-14
DK0593639T3 (da) 1995-07-03
EP0527069A1 (fr) 1993-02-10
KR100234927B1 (ko) 2000-02-01
HUT70403A (en) 1995-10-30
NZ243514A (en) 1995-03-28
JPH06509331A (ja) 1994-10-20
PL171054B1 (pl) 1997-02-28
HU223470B1 (hu) 2004-07-28
ES2071510T3 (es) 1995-06-16
DE69201956T2 (de) 1995-11-30
HU9400061D0 (en) 1994-05-30
RU2118316C1 (ru) 1998-08-27
CA2102697C (fr) 2003-09-30
AU2327592A (en) 1993-02-11
WO1993001167A1 (fr) 1993-01-21
PL171112B1 (pl) 1997-03-28
PL171333B1 (pl) 1997-04-30
IE922244A1 (en) 1993-01-13
CZ283602B6 (cs) 1998-05-13
NO934300L (no) 1993-11-26
EP0593639A1 (fr) 1994-04-27
ZA925128B (en) 1993-04-28
NO180166B (no) 1996-11-18
EP0593639B1 (fr) 1995-04-05
CA2102697A1 (fr) 1993-01-11
JP3034043B2 (ja) 2000-04-17
SK1694A3 (en) 1994-12-07
FR2678938B1 (fr) 1993-10-08
PL171095B1 (pl) 1997-03-28

Similar Documents

Publication Publication Date Title
NO934300L (no) Pyrrolidin- og tiazolidinderivater, deres fremstilling samt medikamenter inneholdende forbindelsene
NO921835D0 (no) Fremgangsmaate for fremstilling av amidinofenylalaninderivat samt anvendelse derav
FI914928A0 (fi) Hydroximetyl (metylencyklopentyl) puriner och -pyrimidiner.
SE8900727D0 (sv) Piperazinderivat och dess salt foerfarande foer framstaellning daerav samt farmaceutisk komposition som innehaaller detsamma som aktiv komponent
FI935360A0 (fi) Guanidinalkyl-1,1-bifosfonsyraderivat, foerfarande foer deras framstaellning samt deras anvaendning
ATE84413T1 (de) Arzneimittel, enthaltend di-tert.butylhydroxyphenyl-derivatesowie neue derivate.
DK324185D0 (da) 2-substituerede 1,3-propylidendiphosphonatderivater, deres fremstilling og farmaceutiske praeparater med indhold deraf
DK297385D0 (da) Carbapenemer med externt alkyleret mono- eller bicyclisk heteroarylalkylthiosubstituent samt laegemiddel indeholdende saadanne forbindelser
DK297485D0 (da) Carbapenemer med kvaternaere heteroarylalkylthio 2-substituenter samt laegemiddel indeholdende saadanne forbindelser
AU654125B2 (en) Novel diphenylthyazole derivative
ES2123728T3 (es) Derivados de pirrolo-pirazina de actividad 5-ht3.
DK284588D0 (da) Beta-lactam-forbindelser, deres fremstilling og anvendelse som laegemidler.
ES2098517T3 (es) Derivados de 1,2,4-tiadiazino(3,4-b)benzotiazol, su preparacion y los medicamentos que los contienen.
YU47723B (sh) Postupak za dobivanje derivata 2-imino-3-heterocikloalkilbenzotiazolina
SE8601963D0 (sv) O-sulfated beta-lactam hydroxamic acids
ES2093051T3 (es) Purinil- y pirimidil-tetrahidrofuranos.
DK0418990T3 (da) 13-brom- og 13,14-dibrom-ergoliner, deres fremstilling og anvendelse i lægemidler
DK656889A (da) Azabicykliske derivater
DK0631777T3 (da) Anvendelse af beta-naphtoquinonderivater til hæmning af blodpladesammenklumpning
ATE60048T1 (de) Aminoverbindungen und diese enthaltende fungizide.
ATE119394T1 (de) Verwendung von myricetin-3-0-beta-d-glucuronid als arzneimittel.
DK0478941T3 (da) Lægemidler indeholdende substituerede 2-cyclohexen-1-yl-amin-derivater og deres anvendelse til bekæmpelse af sygdomme
ATE92069T1 (de) 4-substituierte 10-cyanmethylenpyrrolo(4,3-e>benzo-azepine.
NO901418L (no) Cefalosporinderivater og deres fremstilling.
DK0583806T3 (da) Acrylderivater af 2-thiazolylpyrroler med fungicid aktivitet

Legal Events

Date Code Title Description
MK1K Patent expired