NO921000D0 - Hydrazonderivater, fremgangsmaate for fremstilling derav samt anvendelse derav - Google Patents
Hydrazonderivater, fremgangsmaate for fremstilling derav samt anvendelse deravInfo
- Publication number
- NO921000D0 NO921000D0 NO921000A NO921000A NO921000D0 NO 921000 D0 NO921000 D0 NO 921000D0 NO 921000 A NO921000 A NO 921000A NO 921000 A NO921000 A NO 921000A NO 921000 D0 NO921000 D0 NO 921000D0
- Authority
- NO
- Norway
- Prior art keywords
- alkyl
- hydrogen
- independently
- benzyl
- so2nr
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 150000007857 hydrazones Chemical class 0.000 title 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 8
- 229910052739 hydrogen Inorganic materials 0.000 abstract 8
- 239000001257 hydrogen Substances 0.000 abstract 8
- 150000002431 hydrogen Chemical class 0.000 abstract 6
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 5
- 150000001875 compounds Chemical class 0.000 abstract 4
- 229910052736 halogen Inorganic materials 0.000 abstract 4
- 150000002367 halogens Chemical class 0.000 abstract 4
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 4
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 2
- 125000003627 8 membered carbocyclic group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 229920006395 saturated elastomer Polymers 0.000 abstract 2
- 125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical compound O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 208000015114 central nervous system disease Diseases 0.000 abstract 1
- 239000003257 excitatory amino acid Substances 0.000 abstract 1
- 230000002461 excitatory amino acid Effects 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/40—Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/60—Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Holo Graphy (AREA)
- Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/670,061 US5164404A (en) | 1991-03-15 | 1991-03-15 | Hydrazone derivatives and their use |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO921000D0 true NO921000D0 (no) | 1992-03-13 |
| NO921000L NO921000L (no) | 1992-09-16 |
| NO180191B NO180191B (no) | 1996-11-25 |
| NO180191C NO180191C (no) | 1997-03-05 |
Family
ID=24688827
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO921000A NO180191C (no) | 1991-03-15 | 1992-03-13 | Hydrazonderivater, farmasöytiske preparater derav samt anvendelse av hydrazonforbindelser for fremstilling av et medikament |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5164404A (no) |
| EP (1) | EP0503349B1 (no) |
| JP (1) | JP3407896B2 (no) |
| KR (1) | KR100192641B1 (no) |
| AT (1) | ATE116639T1 (no) |
| AU (1) | AU643877B2 (no) |
| CA (1) | CA2062853A1 (no) |
| DE (1) | DE69201068T2 (no) |
| DK (1) | DK0503349T3 (no) |
| ES (1) | ES2069330T3 (no) |
| FI (1) | FI103276B (no) |
| GR (1) | GR3015671T3 (no) |
| IE (1) | IE66111B1 (no) |
| NO (1) | NO180191C (no) |
| NZ (1) | NZ241752A (no) |
| ZA (1) | ZA921328B (no) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9109007D0 (en) * | 1991-04-26 | 1991-06-12 | Merck Sharp & Dohme | Therapeutic method |
| AU655643B2 (en) * | 1991-07-09 | 1995-01-05 | Neurosearch A/S | Novel isatineoxime derivatives, their preparation and use |
| DK69693D0 (da) * | 1993-06-14 | 1993-06-14 | Neurosearch As | Farven lilla |
| US5565580A (en) * | 1994-01-27 | 1996-10-15 | Neurosearch A/S | Glutamate Antagonists |
| US5773434A (en) * | 1995-08-30 | 1998-06-30 | Gary A. Rogers | Facilitation of AMPA receptor-mediated synaptic transmission in brain as a treatment for schizophrenia |
| KR19980050063A (ko) * | 1996-12-20 | 1998-09-15 | 이덕림 | 신규한 하이드라존 유도체 |
| AR016551A1 (es) * | 1997-07-30 | 2001-07-25 | Smithkline Beecham Corp | Derivados de 2-oxindol, composiciones farmaceuticas que los comprenden y el uso de los mismos para la manufactura de medicamentos |
| AR016384A1 (es) * | 1997-07-30 | 2001-07-04 | Smithkline Beecham Corp | Inhibidores de caspasas, composiciones farmaceuticas que comprenden dichos inhibidores de caspasas y uso de los inhibidores de caspasas para prepararun medicamento util para el tratamiento de apoptosis y desordenes asociados con excesiva actividad de la convertosa il-1 beta. |
| GB9718913D0 (en) | 1997-09-05 | 1997-11-12 | Glaxo Group Ltd | Substituted oxindole derivatives |
| ATE249828T1 (de) | 1998-03-06 | 2003-10-15 | Astrazeneca Ab | Verwendung von isatin- und oxindolderivaten zur herstellung von arzeneimittel für die behandlung von mykobakteriellen erkrankungen |
| GB9904933D0 (en) | 1999-03-04 | 1999-04-28 | Glaxo Group Ltd | Compounds |
| US6624171B1 (en) | 1999-03-04 | 2003-09-23 | Smithkline Beecham Corporation | Substituted aza-oxindole derivatives |
| US6492398B1 (en) | 1999-03-04 | 2002-12-10 | Smithkline Beechman Corporation | Thiazoloindolinone compounds |
| AU7625500A (en) * | 1999-09-30 | 2001-04-30 | Smithkline Beecham Corporation | Caspases and apoptosis |
| US6620818B1 (en) | 2000-03-01 | 2003-09-16 | Smithkline Beecham Corporation | Method for reducing the severity of side effects of chemotherapy and/or radiation therapy |
| US6589504B1 (en) * | 2000-09-22 | 2003-07-08 | Pharmacia & Upjohn Company | Compounds and methods for diagnosing and treating amyloid-related conditions |
| US7186745B2 (en) | 2001-03-06 | 2007-03-06 | Astrazeneca Ab | Indolone derivatives having vascular damaging activity |
| CN100569076C (zh) * | 2004-05-12 | 2009-12-16 | 拜尔作物科学有限公司 | 植物生长调节作用 |
| WO2005118551A2 (en) * | 2004-05-28 | 2005-12-15 | Ligand Pharmaceuticals Inc. | Thrombopoietin activity modulating compounds and methods |
| NZ554662A (en) * | 2004-10-25 | 2008-11-28 | Ligand Pharm Inc | Thrombopoietin activity modulating compounds and methods |
| EP2338492A1 (en) | 2009-12-24 | 2011-06-29 | Universidad del Pais Vasco | Methods and compositions for the treatment of alzheimer |
| CN115304536B (zh) * | 2022-07-26 | 2023-09-22 | 合肥工业大学 | 一种吲哚啉-2-酮化合物衍生物的制备及用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3966900A (en) | 1969-03-12 | 1976-06-29 | Airwick Industries, Inc. | Evaporator system comprising a stabilized pesticidal phosphoric acid ester and method for stabilizing such ester enclosed in an evaporator |
| DE2314242A1 (de) * | 1973-03-22 | 1974-09-26 | Bayer Ag | Neue 3-substituierte 2-oxo-4-hydroxy1,2,3,4-tetrahydrochinazolin-4-carbonsaeurehydrazide |
| US4780477A (en) * | 1985-06-08 | 1988-10-25 | Kissei Pharmaceutical Co., Ltd. | Isatin compositions having anti-ulcer activities |
| US4988710A (en) * | 1989-08-25 | 1991-01-29 | Washington University | Aryl-cycloalkyl-alkanolamines for treatment of cholinergic neurotoxins |
| IE69677B1 (en) * | 1989-12-11 | 1996-10-02 | Neurosearch As | Isatine derivatives their preparation and use |
-
1991
- 1991-03-15 US US07/670,061 patent/US5164404A/en not_active Expired - Fee Related
-
1992
- 1992-02-24 AT AT92103104T patent/ATE116639T1/de not_active IP Right Cessation
- 1992-02-24 DE DE69201068T patent/DE69201068T2/de not_active Expired - Fee Related
- 1992-02-24 DK DK92103104.3T patent/DK0503349T3/da active
- 1992-02-24 ZA ZA921328A patent/ZA921328B/xx unknown
- 1992-02-24 EP EP92103104A patent/EP0503349B1/en not_active Expired - Lifetime
- 1992-02-24 ES ES92103104T patent/ES2069330T3/es not_active Expired - Lifetime
- 1992-02-26 NZ NZ241752A patent/NZ241752A/en unknown
- 1992-02-26 AU AU11225/92A patent/AU643877B2/en not_active Ceased
- 1992-02-28 IE IE920643A patent/IE66111B1/en not_active IP Right Cessation
- 1992-03-11 FI FI921049A patent/FI103276B/fi not_active IP Right Cessation
- 1992-03-12 CA CA002062853A patent/CA2062853A1/en not_active Abandoned
- 1992-03-13 JP JP05553192A patent/JP3407896B2/ja not_active Expired - Fee Related
- 1992-03-13 NO NO921000A patent/NO180191C/no not_active IP Right Cessation
- 1992-03-13 KR KR1019920004115A patent/KR100192641B1/ko not_active Expired - Fee Related
-
1995
- 1995-04-03 GR GR950400815T patent/GR3015671T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US5164404A (en) | 1992-11-17 |
| IE920643A1 (en) | 1992-09-23 |
| GR3015671T3 (en) | 1995-07-31 |
| FI921049L (fi) | 1992-09-16 |
| NO180191B (no) | 1996-11-25 |
| AU643877B2 (en) | 1993-11-25 |
| AU1122592A (en) | 1992-09-17 |
| DE69201068T2 (de) | 1995-05-11 |
| FI103276B1 (fi) | 1999-05-31 |
| FI103276B (fi) | 1999-05-31 |
| DE69201068D1 (de) | 1995-02-16 |
| ES2069330T3 (es) | 1995-05-01 |
| NO921000L (no) | 1992-09-16 |
| CA2062853A1 (en) | 1992-09-16 |
| FI921049A0 (fi) | 1992-03-11 |
| ATE116639T1 (de) | 1995-01-15 |
| JPH0578350A (ja) | 1993-03-30 |
| IE66111B1 (en) | 1995-12-13 |
| KR920017650A (ko) | 1992-10-21 |
| ZA921328B (en) | 1992-11-25 |
| DK0503349T3 (da) | 1995-05-08 |
| EP0503349B1 (en) | 1995-01-04 |
| KR100192641B1 (ko) | 1999-06-15 |
| JP3407896B2 (ja) | 2003-05-19 |
| NZ241752A (en) | 1994-05-26 |
| EP0503349A1 (en) | 1992-09-16 |
| NO180191C (no) | 1997-03-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO921000L (no) | Hydrazonderivater, fremgangsmaate for fremstilling derav samt anvendelse derav | |
| DK46789D0 (da) | 3-indolpyrodruesyrederivater og farmaceutisk anvendelse deraf | |
| DE3263734D1 (en) | Derivatives of 1-aryl-2-aminomethyl-cyclopropane-carboxamides (z), their preparation and their use as medicines in the treatment of disorders of the central nervous system | |
| DK0432648T3 (da) | Isatinderivater, deres fremstilling og anvendelse | |
| HUP0002830A2 (hu) | Indol- és 2,3-dihidroindol-származékok, előállításuk és gyógyászati alkalmazásuk | |
| ES2157565T3 (es) | N-azacicloalquilalquildibenzotiofenocarboxamidas: ligandos especificos de un subtipo de receptor de la dopamina. | |
| DE69705210D1 (de) | Krampflösende, enantiomere aminosäure-derivate | |
| DE3852935D1 (de) | Substituierte Alpha-Aminosäuren mit pharmazeutischer Aktivität. | |
| ES2341958T3 (es) | Derivados de 2-aminobenzoilo. | |
| ATE229953T1 (de) | Naphtho-imidazo(1,2-a)pyridin derivate, deren herstellung und deren verwendung in der behandlung von störungen des zentralnervensystems | |
| DK0633262T3 (da) | Hidtil ukendte isatinoximderivater samt fremstilling og anvendelse heraf | |
| DE69827706D1 (de) | 5-(Heteroaryl)alkyl)-3-oxo-pyrido(1,2-a)benzimidazol-4-carboxamid (PBI) Derivate zur Behandlung von Störungen des zentralen Nervensystems | |
| DE68915595D1 (de) | Verwendung von Isoxazolinonen als cerebro-aktive Medikamente. | |
| TH30603A (th) | สารประกอบแบบใหม่ | |
| IT8509443A0 (it) | Interforometro per spettroscopia dell'ultravioletto e visibile del tipo trasformata di fourier, senza parti mobili |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |