NO924857L - 17-spirofuran-3'-yliden-steroider - Google Patents

17-spirofuran-3'-yliden-steroider

Info

Publication number: NO924857L
Authority: NO; Norway
Prior art keywords: lower alkyl; spirofuran; hydrogen; ylidene; steroid
Prior art date: 1991-12-20

Application number

NO92924857A

Other languages

English (en)

Other versions

NO924857D0 (no

NO302525B1 (no

Inventor

Johannes Antonius Mar Hamersma

Everardus Otto Maria Orlemans

Original Assignee

Akzo Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-12-20

Filing date

1992-12-15

Publication date

1993-06-21

1992-12-15 Application filed by Akzo Nv filed Critical Akzo Nv

1992-12-15 Publication of NO924857D0 publication Critical patent/NO924857D0/no

1993-06-21 Publication of NO924857L publication Critical patent/NO924857L/no

1998-03-16 Publication of NO302525B1 publication Critical patent/NO302525B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/36—Antigestagens
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
- C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

NO924857A 1991-12-20 1992-12-15 17-spirofuran-3'-yliden-steroider NO302525B1 (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP91203366		1991-12-20

Publications (3)

Publication Number	Publication Date
NO924857D0 NO924857D0 (no)	1992-12-15
NO924857L true NO924857L (no)	1993-06-21
NO302525B1 NO302525B1 (no)	1998-03-16

Family

ID=8208088

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO924857A NO302525B1 (no)	1991-12-20	1992-12-15	17-spirofuran-3'-yliden-steroider

Country Status (16)

Country	Link
US (1)	US5292878A (no)
EP (1)	EP0549041B1 (no)
JP (1)	JP3462515B2 (no)
KR (1)	KR100287513B1 (no)
AT (1)	ATE128983T1 (no)
AU (1)	AU655858B2 (no)
CA (1)	CA2084431C (no)
DE (1)	DE69205405T2 (no)
DK (1)	DK0549041T3 (no)
ES (1)	ES2081040T3 (no)
FI (1)	FI104178B1 (no)
GR (1)	GR3018630T3 (no)
MX (1)	MX9207394A (no)
NO (1)	NO302525B1 (no)
NZ (1)	NZ245520A (no)
ZA (1)	ZA929315B (no)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2100514C (en) *	1992-07-29	2005-03-29	Johannes A. M. Hamersma	17-spiromethylene steroids
BR9814136A (pt)	1997-11-14	2000-10-03	Akzo Nobel Nv	Conjunto contraceptivo, processos de fabricação do mesmo e de tratamento de sangramento, usos de anti-progestogênio, de progestogênio e de anti-progestogênio, e, de um composto.
US6020328A (en) *	1998-03-06	2000-02-01	Research Triangle Institute	20-keto-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties
ATE473759T1 (de)	1998-05-22	2010-07-15	Univ Leland Stanford Junior	Bifunktionelle moleküle sowie darauf basierende therapien.
US6262042B1 (en)	1998-05-29	2001-07-17	Research Triangle Institute	17β-amino and hydroxylamino-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties
US5962444A (en) *	1998-05-29	1999-10-05	Research Triangle Institute	17β-nitro-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties
CN1349405A (zh) *	1999-04-29	2002-05-15	阿克佐诺贝尔公司	抗结合孕激素在联合疗法中的应用
US6043235A (en) *	1999-07-21	2000-03-28	Research Triangle Institute	11β-aryl-17, 17-spirothiolane-substituted steroids
US7426602B2 (en) *	2004-01-08	2008-09-16	Topside Research, Llc	Switch for bus optimization
TW200531977A (en)	2004-03-25	2005-10-01	Akzo Nobel Nv	Progesterone receptor modulators
CN101287411B (zh)	2005-04-28	2013-03-06	普罗秋斯生物医学公司	药物信息系统及其用途
WO2007035716A2 (en)	2005-09-16	2007-03-29	Raptor Pharmaceutical Inc.	Compositions comprising receptor-associated protein (rap) variants specific for cr-containing proteins and uses thereof
ATE453660T1 (de) *	2006-02-17	2010-01-15	Janssen Pharmaceutica Nv	17-phosphor-steroid-derivate als progesteron- rezeptormodulatoren
EP1989217B1 (en)	2006-02-17	2012-06-27	Janssen Pharmaceutica N.V.	11-phosphorous steroid derivatives useful as progesterone receptor modulators
ES2643318T3 (es)	2006-10-24	2017-11-22	Repros Therapeutics Inc.	Composiciones y métodos para suprimir la proliferación endometrial
TWI539953B (zh)	2008-04-28	2016-07-01	瑞波若斯治療學公司	用於治療乳癌之組成物和方法
HUE059078T2 (hu)	2009-02-20	2022-10-28	Enhanx Biopharm Inc	Glutation-alapú hatóanyagszállító rendszer
US8673968B2 (en) *	2009-04-06	2014-03-18	Evestra, Inc.	Progesterone antagonists
KR101909711B1 (ko)	2009-05-06	2018-12-19	라보라토리 스킨 케어, 인크.	활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
CN101926806A (zh) *	2009-06-24	2010-12-29	天津金耀集团有限公司	一种17磷类雌甾化合物在制备紧急避孕药物中的应用
EP2550288A1 (en)	2010-03-22	2013-01-30	Repros Therapeutics Inc.	Compositions and methods for non-toxic delivery of antiprogestins
WO2011157443A1 (en)	2010-06-17	2011-12-22	N.V. Organon	(11b,17a)-11-(4-(2-11c-acetyl)phenyl)-17,23-epoxy-19,24-dinorchola-4,9,20-trien-3-one
US9096641B2 (en)	2013-06-05	2015-08-04	Evestra, Inc.	Imidazolyl progesterone antagonists

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3461090D1 (en) *	1983-02-18	1986-12-04	Schering Ag	11-beta-aryl-estradienes, process for their preparation and pharmaceutical compositions containing them
FR2596395B1 (fr) *	1986-03-26	1989-05-26	Roussel Uclaf	Nouveaux steroides comportant un cycle spirannique en position 17, leur procede de preparation, leur application comme medicaments et les compositions les renfermant
DE3761308D1 (de) *	1986-07-23	1990-02-08	Akzo Nv	18-phenylestrane-derivate.
IE60780B1 (en) *	1987-01-23	1994-08-10	Akzo Nv	New 11-aryl steroid derivatives
ES2045082T3 (es) *	1987-04-24	1994-01-16	Akzo Nv	Un metodo para la preparacion de nuevos derivados 11-arilestrano y 11-arilpregnano.
ES2053714T3 (es) *	1987-12-12	1994-08-01	Akzo Nv	Proceso para la preparacion de 11-arilesteroides.

1992
- 1992-12-01 ZA ZA929315A patent/ZA929315B/xx unknown
- 1992-12-03 CA CA002084431A patent/CA2084431C/en not_active Expired - Fee Related
- 1992-12-11 AU AU30093/92A patent/AU655858B2/en not_active Ceased
- 1992-12-15 AT AT92203923T patent/ATE128983T1/de not_active IP Right Cessation
- 1992-12-15 DE DE69205405T patent/DE69205405T2/de not_active Expired - Fee Related
- 1992-12-15 NO NO924857A patent/NO302525B1/no unknown
- 1992-12-15 EP EP92203923A patent/EP0549041B1/en not_active Expired - Lifetime
- 1992-12-15 DK DK92203923.5T patent/DK0549041T3/da active
- 1992-12-15 ES ES92203923T patent/ES2081040T3/es not_active Expired - Lifetime
- 1992-12-17 KR KR1019920024581A patent/KR100287513B1/ko not_active Expired - Fee Related
- 1992-12-17 MX MX9207394A patent/MX9207394A/es not_active IP Right Cessation
- 1992-12-18 NZ NZ245520A patent/NZ245520A/en unknown
- 1992-12-18 FI FI925790A patent/FI104178B1/fi active
- 1992-12-18 JP JP33883092A patent/JP3462515B2/ja not_active Expired - Fee Related
- 1992-12-21 US US07/994,039 patent/US5292878A/en not_active Expired - Lifetime
1996
- 1996-01-10 GR GR960400050T patent/GR3018630T3/el unknown

Also Published As

Publication number	Publication date
US5292878A (en)	1994-03-08
MX9207394A (es)	1993-07-30
NO924857D0 (no)	1992-12-15
NO302525B1 (no)	1998-03-16
GR3018630T3 (en)	1996-04-30
ZA929315B (en)	1993-05-24
AU3009392A (en)	1993-06-24
EP0549041B1 (en)	1995-10-11
DE69205405D1 (de)	1995-11-16
AU655858B2 (en)	1995-01-12
ES2081040T3 (es)	1996-02-16
HK1002033A1 (en)	1998-07-24
NZ245520A (en)	1995-02-24
CA2084431A1 (en)	1993-06-21
EP0549041A1 (en)	1993-06-30
JP3462515B2 (ja)	2003-11-05
KR100287513B1 (ko)	2001-05-02
FI925790L (fi)	1993-06-21
CA2084431C (en)	2003-04-08
DE69205405T2 (de)	1996-05-09
FI104178B (fi)	1999-11-30
ATE128983T1 (de)	1995-10-15
DK0549041T3 (da)	1996-01-29
JPH05255380A (ja)	1993-10-05
FI104178B1 (fi)	1999-11-30
FI925790A0 (fi)	1992-12-18

Publication	Publication Date	Title
FI104178B1 (fi)	1999-11-30	17-spirofuran-3'-ylideenisteroidit
DE69416306D1 (de)	1999-03-11	Sphingoglycolipid und verwendung davon
BR1100621A (pt)	1999-12-07	Compostos
FI955108A0 (fi)	1995-10-26	Steroideja, jotka sisältävät 17-spiromtyleenilaktoni- tai laktoliryhmän
ATE229968T1 (de)	2003-01-15	Diagnostisches mittel zur glykostoffwechselfunktion
NO940777D0 (no)	1994-03-04	Anvendelse av et pregnanderivat
FI821486A0 (fi)	1982-04-28	4'-halogensubstituerade sakkarosderivater
EP0424194A3 (en)	1991-09-25	Benzanilides
CS742082A2 (en)	1985-08-15	Zpusob vyroby substituovanych thiazolidinylesteru mineralnich kyselin
FR2362148A1 (fr)	1978-03-17	Composes silices polyethyleniques
FR2501676B1 (no)	1985-05-17
ATE73136T1 (de)	1992-03-15	Verfahren zur herstellung von 6alpha, 9alphadifluor-11beta, 17alpha-dihydroxy-16alpha-methyl4-pregnen-3,20-dion und dessen derivate.
IL117497A0 (en)	1996-07-23	17-Difluoromethylene estratriene derivatives and pharmaceutical compositions containing the same
DE69106459D1 (de)	1995-02-16	2-Acyloxy-4-morpholinyl-Anthracyclin.
FR2493846B1 (no)	1983-01-21
DE69615814D1 (de)	2001-11-15	Uch-15-verbindungen
YU49004B (sh)	2003-04-30	LANOSTA-7,9-DIEN-3Гџ, 32-DIOL I POSTUPAK ZA NJEGOVO DOBIJANJE
IT8603380A1 (it)	1987-10-04	Ventilatore perfezionato per l'areazione di ambienti chiusi