[go: up one dir, main page]

NO910201L - Borsyreaddukter av rheniumdioksim og technetium-99 m- dioksimkomplekser inneholdende en biokjemisk aktiv gruppe. - Google Patents

Borsyreaddukter av rheniumdioksim og technetium-99 m- dioksimkomplekser inneholdende en biokjemisk aktiv gruppe.

Info

Publication number
NO910201L
NO910201L NO91910201A NO910201A NO910201L NO 910201 L NO910201 L NO 910201L NO 91910201 A NO91910201 A NO 91910201A NO 910201 A NO910201 A NO 910201A NO 910201 L NO910201 L NO 910201L
Authority
NO
Norway
Prior art keywords
technetium
boric acid
dioxym
dioxim
rhenium
Prior art date
Application number
NO91910201A
Other languages
English (en)
Norwegian (no)
Other versions
NO910201D0 (no
Inventor
Adrian D Nunn
Karen E Linder
Silvia Jurisson
William C Eckelman
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of NO910201D0 publication Critical patent/NO910201D0/no
Publication of NO910201L publication Critical patent/NO910201L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005—Compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO91910201A 1990-01-18 1991-01-17 Borsyreaddukter av rheniumdioksim og technetium-99 m- dioksimkomplekser inneholdende en biokjemisk aktiv gruppe. NO910201L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US46688490A 1990-01-18 1990-01-18

Publications (2)

Publication Number Publication Date
NO910201D0 NO910201D0 (no) 1991-01-17
NO910201L true NO910201L (no) 1991-07-19

Family

ID=23853463

Family Applications (1)

Application Number Title Priority Date Filing Date
NO91910201A NO910201L (no) 1990-01-18 1991-01-17 Borsyreaddukter av rheniumdioksim og technetium-99 m- dioksimkomplekser inneholdende en biokjemisk aktiv gruppe.

Country Status (18)

Country Link
US (1) US5387409A (fr)
EP (1) EP0441491A1 (fr)
JP (1) JPH04212099A (fr)
KR (1) KR100191568B1 (fr)
CN (3) CN1034078C (fr)
AU (2) AU651076B2 (fr)
CA (1) CA2034042C (fr)
FI (1) FI910274A7 (fr)
HU (1) HU910155D0 (fr)
IE (1) IE910133A1 (fr)
IL (1) IL96946A (fr)
MX (1) MX24177A (fr)
MY (1) MY105482A (fr)
NO (1) NO910201L (fr)
NZ (1) NZ236789A (fr)
PT (1) PT96518B (fr)
YU (1) YU26691A (fr)
ZA (1) ZA91300B (fr)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5256394A (en) * 1991-10-23 1993-10-26 Boron Biologicals, Inc. Radiological imaging method, and contrast media reagents therefor
US6359120B1 (en) 1991-10-29 2002-03-19 Bracco International B.V. Rhenium and technetium complexes containing a hypoxia-localizing moiety
US5808091A (en) * 1991-10-29 1998-09-15 Bracco International B.V. Rhenium and technetium complexes containing a hypoxia localizing moiety
FR2690443B1 (fr) * 1992-04-10 1995-06-30 Wallone Region Marquage des hormones par le rhenium et le technetium.
US5608110A (en) * 1993-06-15 1997-03-04 Bracco International B.V. Heteroatom-bearing ligands and metal complexes thereof
WO1995009844A1 (fr) * 1993-10-04 1995-04-13 Board Of Regents, The University Of Texas System Synthese rapide et utilisation de 18f-fluoromisonidazole et d'analogues
WO1995019338A1 (fr) * 1994-01-12 1995-07-20 Bracco International B.V. Ligands et leurs complexes metalliques
AU696788B2 (en) * 1994-06-27 1998-09-17 Neutron Therapies Inc. Boron-containing hormone analogs and methods of their use in imaging or killing cells having hormone receptors
KR100430061B1 (ko) * 2000-03-21 2004-05-03 재단법인 아산사회복지재단 글루코스 유도체에 방사성 동위원소가 표지된 착화합물 및이를 생산하기 위한 조성물이 포함된 키트
US8909325B2 (en) * 2000-08-21 2014-12-09 Biosensors International Group, Ltd. Radioactive emission detector equipped with a position tracking system and utilization thereof with medical systems and in medical procedures
WO2005119025A2 (fr) 2004-06-01 2005-12-15 Spectrum Dynamics Llc Optimisation de la mesure d'emissions radioactives dans des structures corporelles specifiques
US8565860B2 (en) * 2000-08-21 2013-10-22 Biosensors International Group, Ltd. Radioactive emission detector equipped with a position tracking system
US8489176B1 (en) 2000-08-21 2013-07-16 Spectrum Dynamics Llc Radioactive emission detector equipped with a position tracking system and utilization thereof with medical systems and in medical procedures
SI2301587T1 (sl) 2002-03-01 2014-11-28 Dyax Corp. KDR in VEGF/KDR vezavni peptidi in njihova uporaba pri diagnozi
US7261876B2 (en) 2002-03-01 2007-08-28 Bracco International Bv Multivalent constructs for therapeutic and diagnostic applications
US20050100963A1 (en) * 2002-03-01 2005-05-12 Dyax Corporation KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
US7794693B2 (en) 2002-03-01 2010-09-14 Bracco International B.V. Targeting vector-phospholipid conjugates
US7211240B2 (en) * 2002-03-01 2007-05-01 Bracco International B.V. Multivalent constructs for therapeutic and diagnostic applications
US8623822B2 (en) * 2002-03-01 2014-01-07 Bracco Suisse Sa KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
US20040204646A1 (en) * 2002-11-04 2004-10-14 V-Target Technologies Ltd. Intracorporeal-imaging head
US7226577B2 (en) 2003-01-13 2007-06-05 Bracco Imaging, S. P. A. Gastrin releasing peptide compounds
AU2004217894B2 (en) 2003-03-03 2010-07-15 Bracco International B.V. Peptides that specifically bind HGF receptor (cMet) and uses thereof
SG144160A1 (en) * 2003-07-24 2008-07-29 Bracco Imaging Spa Stable radiopharmaceutical compositions and methods for their preparation
WO2006051531A2 (fr) * 2004-11-09 2006-05-18 Spectrum Dynamics Llc Radio-imagerie
US9040016B2 (en) * 2004-01-13 2015-05-26 Biosensors International Group, Ltd. Diagnostic kit and methods for radioimaging myocardial perfusion
US8586932B2 (en) * 2004-11-09 2013-11-19 Spectrum Dynamics Llc System and method for radioactive emission measurement
WO2006054296A2 (fr) * 2004-11-17 2006-05-26 Spectrum Dynamics Llc Methodes pour detecter le cancer de la prostate
US7968851B2 (en) 2004-01-13 2011-06-28 Spectrum Dynamics Llc Dynamic spect camera
WO2007010534A2 (fr) * 2005-07-19 2007-01-25 Spectrum Dynamics Llc Protocoles d'imagerie
US9470801B2 (en) * 2004-01-13 2016-10-18 Spectrum Dynamics Llc Gating with anatomically varying durations
CN1981210A (zh) * 2004-01-13 2007-06-13 光谱动力学有限责任公司 多维图像重构
US8571881B2 (en) 2004-11-09 2013-10-29 Spectrum Dynamics, Llc Radiopharmaceutical dispensing, administration, and imaging
US9943274B2 (en) 2004-11-09 2018-04-17 Spectrum Dynamics Medical Limited Radioimaging using low dose isotope
US8423125B2 (en) * 2004-11-09 2013-04-16 Spectrum Dynamics Llc Radioimaging
US9316743B2 (en) 2004-11-09 2016-04-19 Biosensors International Group, Ltd. System and method for radioactive emission measurement
US8615405B2 (en) 2004-11-09 2013-12-24 Biosensors International Group, Ltd. Imaging system customization using data from radiopharmaceutical-associated data carrier
WO2008059489A2 (fr) 2006-11-13 2008-05-22 Spectrum Dynamics Llc Application à la radioimagerie de nouvelles formules de téboroxime
US8837793B2 (en) 2005-07-19 2014-09-16 Biosensors International Group, Ltd. Reconstruction stabilizer and active vision
US8894974B2 (en) * 2006-05-11 2014-11-25 Spectrum Dynamics Llc Radiopharmaceuticals for diagnosis and therapy
EP2097438B1 (fr) 2006-12-11 2015-08-26 Bracco Imaging S.p.A Conjugues peptidiques se liant a la fibrine pour des applications de diagnostic et therapeutiques
WO2008075362A2 (fr) * 2006-12-20 2008-06-26 Spectrum Dynamics Llc Procédé, système et appareil pour utiliser et traiter des données multidimensionnelles
US8521253B2 (en) * 2007-10-29 2013-08-27 Spectrum Dynamics Llc Prostate imaging
EP2147684A1 (fr) 2008-07-22 2010-01-27 Bracco Imaging S.p.A Agents de diagnostics sélectifs contre les métalloprotéases
WO2010107832A1 (fr) 2009-03-17 2010-09-23 Bracco Imaging Spa Analogues peptidiques de la lhrh-ii
US8338788B2 (en) 2009-07-29 2012-12-25 Spectrum Dynamics Llc Method and system of optimized volumetric imaging
CN102030797B (zh) * 2009-09-24 2013-03-20 中国科学院上海应用物理研究所 锝标记雌二醇类衍生物及其参照化合物及其制备方法、应用和其中间体
WO2015171543A1 (fr) 2014-05-05 2015-11-12 California Institute Of Technology Agents de capture mutants spécifiques d'akt, compositions et procédés d'utilisation et de préparation associés
IL256833B2 (en) 2015-07-15 2025-07-01 California Inst Of Techn IL-17F-specific binding agents, compositions and methods of use and preparation
BR112018015143A2 (en) 2016-02-09 2018-12-18 Bracco Suisse Sa recombinant chimeric protein for selectin targeting
US20170319722A1 (en) 2016-04-04 2017-11-09 Indi Molecular, Inc. Cd8-specific capture agents, compositions, and methods of using and making
EP3519425B1 (fr) 2016-09-29 2024-02-28 Indi Molecular, Inc. Compositions pour la détection, l'inhibition et l'imagerie de l'indoléamine 2,3-dioxygénase 1 (ido1) et leurs méthodes de production et d'utilisation
US11358982B2 (en) 2016-11-01 2022-06-14 Ohio State Innovation Foundation Methods for the iodination of biomolecules
EP3638687A1 (fr) 2017-06-15 2020-04-22 Indi Molecular, Inc. Agents de capture spécifiques d'il-17f et il-17a, compositions et procédés d'utilisation et de production
CN107674098B (zh) * 2017-06-26 2021-12-07 中国医学科学院阜外医院 一类含芳基硼酸的99mTc配合物及其药盒配方和应用
WO2020097531A1 (fr) 2018-11-08 2020-05-14 Indi Molecular, Inc. Agents de capture théranostiques, compositions et procédés d'utilisation et de fabrication
WO2020186091A1 (fr) 2019-03-12 2020-09-17 Indi Molecular, Inc. Épitopes réticulés et leurs méthodes d'utilisation
WO2020236969A1 (fr) 2019-05-20 2020-11-26 Indi Molecular, Inc. Compositions et procédés se rapportant à la détection, à l'inhibition et à l'imagerie de l'indoléamine 2,3-dioxygénase 1 (ido1)
EP3972646A4 (fr) 2019-05-20 2023-06-14 Ohio State Innovation Foundation Complexes d'apohémoglobine-haptoglobine et leurs procédés d'utilisation
US11414460B2 (en) 2019-07-19 2022-08-16 Institute For Systems Biology KRAS-specific capture agents, compositions, and methods of making and using
CN111377968B (zh) * 2020-03-09 2023-07-25 中国医学科学院阜外医院 一类含芳基硼酸的99mTc(Ⅲ)配合物及其药盒配方和应用
WO2022098745A1 (fr) 2020-11-03 2022-05-12 Indi Molecular, Inc. Compositions, systèmes d'administration et méthodes utiles dans la thérapie antitumorale
WO2022098743A1 (fr) 2020-11-03 2022-05-12 Indi Molecular, Inc. Compositions, imagerie et procédés thérapeutiques ciblant le récepteur 1 de folate (folr1)
CN115197261B (zh) * 2022-07-06 2024-05-03 重庆医科大学 噁二氮杂硼衍生物的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3369121A (en) 1966-04-06 1968-02-13 Squibb & Sons Inc Radioactive package and container therefor
US3920995A (en) 1973-05-04 1975-11-18 Squibb & Sons Inc Radioactive material generator
US4431627A (en) * 1980-06-03 1984-02-14 Research Corporation Gamma-emitting receptor-binding 3-quinuclidinyl glycolates; methods of preparation thereof and imaging and assay methods utilizing same
US4705849A (en) * 1985-04-15 1987-11-10 E. R. Squibb & Sons, Inc. Boronic acid adducts of technetium-99m dioxime complexes
US4871836A (en) 1987-10-13 1989-10-03 E. R. Squibb & Sons, Inc. Boronic acid adducts of rhenium and radioactive isotopes of rhenium dioxime complexes
CN1022562C (zh) * 1989-04-08 1993-10-27 中国人民解放军第二军医大学 一种消瘤药——甲硝唑氨酸的合成方法

Also Published As

Publication number Publication date
AU6938591A (en) 1991-07-25
KR910014385A (ko) 1991-08-31
US5387409A (en) 1995-02-07
FI910274A0 (fi) 1991-01-18
CN1120437A (zh) 1996-04-17
FI910274L (fi) 1991-07-19
MX24177A (es) 1993-12-01
IL96946A0 (en) 1992-03-29
IE910133A1 (en) 1991-07-31
EP0441491A1 (fr) 1991-08-14
YU26691A (sh) 1994-05-10
AU7914794A (en) 1995-02-16
PT96518B (pt) 1998-06-30
FI910274A7 (fi) 1991-07-19
HU910155D0 (en) 1991-08-28
CN1111621A (zh) 1995-11-15
CA2034042C (fr) 1999-08-17
JPH04212099A (ja) 1992-08-03
CN1054070A (zh) 1991-08-28
CN1034078C (zh) 1997-02-19
MY105482A (en) 1994-10-31
AU651076B2 (en) 1994-07-14
NO910201D0 (no) 1991-01-17
ZA91300B (en) 1991-11-27
CA2034042A1 (fr) 1991-07-19
NZ236789A (en) 1995-03-28
KR100191568B1 (ko) 1999-06-15
PT96518A (pt) 1991-10-15
IL96946A (en) 1995-12-08

Similar Documents

Publication Publication Date Title
NO910201L (no) Borsyreaddukter av rheniumdioksim og technetium-99 m- dioksimkomplekser inneholdende en biokjemisk aktiv gruppe.
DE69226197D1 (de) Hämoglobine als arzneimittelabgabesystem
ATE76401T1 (de) Durch estergruppen substituierte diamindithiole und davon abgeleitete radioaktiv markierte komplexe.
AU6129090A (en) Chelating agents for forming complexes with radioactive isotopes, metal complexes thereof and use thereof in diagnosis and therapy
DE3370935D1 (en) Stable radiographic imaging agents
NZ215513A (en) Boronic acid adducts of technetium-99m dioxime complexes and use as imaging agents
DK568788A (da) Boronsyreaddukter af rheniumdioximkomplekser
WO1997010852A3 (fr) Agents de chelation amidosulfoniques sulfures bifonctionnels du type xsns pour isotopes radioactifs
GB1305035A (fr)
GB2128612B (en) Improvements in or relating to imaging agents
TR22871A (tr) Birden fazla aktif bilesen ihtiva eden piretroid terkipleri
ATE134988T1 (de) Neue vorangeordnete sechszähnige liganden verwendbar in röntgenologischen bildformenden wirkstoffen
JO1072B1 (en) Antihypertensive therapeutic agents
SE7610681L (sv) Trijodanilider
SU945426A1 (ru) Система автоматического управлени исполнительными органами угледобывающей машины
SE8704066D0 (sv) Sterila geler
GB1470393A (en) Drug for the treatment of radiation sickness
IT8421010V0 (it) Mobile per macchine per cucire di larghezza uguale a quest'ultima e presentante l'antina anteriore conformata ad l con lati disuguali.
JO1497B1 (en) A new remedy for baldness and all hair diseases