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NO910201D0 - Borsyreaddukter av rheniumdioksim og technetium-99 m- dioksimkomplekser inneholdende en biologisk aktiv gruppe. - Google Patents

Borsyreaddukter av rheniumdioksim og technetium-99 m- dioksimkomplekser inneholdende en biologisk aktiv gruppe.

Info

Publication number
NO910201D0
NO910201D0 NO910201A NO910201A NO910201D0 NO 910201 D0 NO910201 D0 NO 910201D0 NO 910201 A NO910201 A NO 910201A NO 910201 A NO910201 A NO 910201A NO 910201 D0 NO910201 D0 NO 910201D0
Authority
NO
Norway
Prior art keywords
dioxym
dioxim
technetium
rhenium
boric acid
Prior art date
Application number
NO910201A
Other languages
English (en)
Other versions
NO910201L (no
Inventor
Adrian D Nunn
Karen E Linder
Silvia Jurisson
William C Eckelman
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of NO910201D0 publication Critical patent/NO910201D0/no
Publication of NO910201L publication Critical patent/NO910201L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J51/00Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0474Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0478Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0497Organic compounds conjugates with a carrier being an organic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005Compounds without a metal-carbon linkage
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/025Boronic and borinic acid compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO91910201A 1990-01-18 1991-01-17 Borsyreaddukter av rheniumdioksim og technetium-99 m- dioksimkomplekser inneholdende en biokjemisk aktiv gruppe. NO910201L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US46688490A 1990-01-18 1990-01-18

Publications (2)

Publication Number Publication Date
NO910201D0 true NO910201D0 (no) 1991-01-17
NO910201L NO910201L (no) 1991-07-19

Family

ID=23853463

Family Applications (1)

Application Number Title Priority Date Filing Date
NO91910201A NO910201L (no) 1990-01-18 1991-01-17 Borsyreaddukter av rheniumdioksim og technetium-99 m- dioksimkomplekser inneholdende en biokjemisk aktiv gruppe.

Country Status (18)

Country Link
US (1) US5387409A (no)
EP (1) EP0441491A1 (no)
JP (1) JPH04212099A (no)
KR (1) KR100191568B1 (no)
CN (3) CN1034078C (no)
AU (2) AU651076B2 (no)
CA (1) CA2034042C (no)
FI (1) FI910274A7 (no)
HU (1) HU910155D0 (no)
IE (1) IE910133A1 (no)
IL (1) IL96946A (no)
MX (1) MX24177A (no)
MY (1) MY105482A (no)
NO (1) NO910201L (no)
NZ (1) NZ236789A (no)
PT (1) PT96518B (no)
YU (1) YU26691A (no)
ZA (1) ZA91300B (no)

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WO1995009844A1 (en) * 1993-10-04 1995-04-13 Board Of Regents, The University Of Texas System Rapid synthesis and use of 18f-fluoromisonidazole and analogs
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US8909325B2 (en) * 2000-08-21 2014-12-09 Biosensors International Group, Ltd. Radioactive emission detector equipped with a position tracking system and utilization thereof with medical systems and in medical procedures
WO2005119025A2 (en) 2004-06-01 2005-12-15 Spectrum Dynamics Llc Radioactive-emission-measurement optimization to specific body structures
US8565860B2 (en) * 2000-08-21 2013-10-22 Biosensors International Group, Ltd. Radioactive emission detector equipped with a position tracking system
US8489176B1 (en) 2000-08-21 2013-07-16 Spectrum Dynamics Llc Radioactive emission detector equipped with a position tracking system and utilization thereof with medical systems and in medical procedures
SI2301587T1 (sl) 2002-03-01 2014-11-28 Dyax Corp. KDR in VEGF/KDR vezavni peptidi in njihova uporaba pri diagnozi
US7261876B2 (en) 2002-03-01 2007-08-28 Bracco International Bv Multivalent constructs for therapeutic and diagnostic applications
US20050100963A1 (en) * 2002-03-01 2005-05-12 Dyax Corporation KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
US7794693B2 (en) 2002-03-01 2010-09-14 Bracco International B.V. Targeting vector-phospholipid conjugates
US7211240B2 (en) * 2002-03-01 2007-05-01 Bracco International B.V. Multivalent constructs for therapeutic and diagnostic applications
US8623822B2 (en) * 2002-03-01 2014-01-07 Bracco Suisse Sa KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
US20040204646A1 (en) * 2002-11-04 2004-10-14 V-Target Technologies Ltd. Intracorporeal-imaging head
US7226577B2 (en) 2003-01-13 2007-06-05 Bracco Imaging, S. P. A. Gastrin releasing peptide compounds
AU2004217894B2 (en) 2003-03-03 2010-07-15 Bracco International B.V. Peptides that specifically bind HGF receptor (cMet) and uses thereof
SG144160A1 (en) * 2003-07-24 2008-07-29 Bracco Imaging Spa Stable radiopharmaceutical compositions and methods for their preparation
WO2006051531A2 (en) * 2004-11-09 2006-05-18 Spectrum Dynamics Llc Radioimaging
US9040016B2 (en) * 2004-01-13 2015-05-26 Biosensors International Group, Ltd. Diagnostic kit and methods for radioimaging myocardial perfusion
US8586932B2 (en) * 2004-11-09 2013-11-19 Spectrum Dynamics Llc System and method for radioactive emission measurement
WO2006054296A2 (en) * 2004-11-17 2006-05-26 Spectrum Dynamics Llc Methods of detecting prostate cancer
US7968851B2 (en) 2004-01-13 2011-06-28 Spectrum Dynamics Llc Dynamic spect camera
WO2007010534A2 (en) * 2005-07-19 2007-01-25 Spectrum Dynamics Llc Imaging protocols
US9470801B2 (en) * 2004-01-13 2016-10-18 Spectrum Dynamics Llc Gating with anatomically varying durations
CN1981210A (zh) * 2004-01-13 2007-06-13 光谱动力学有限责任公司 多维图像重构
US8571881B2 (en) 2004-11-09 2013-10-29 Spectrum Dynamics, Llc Radiopharmaceutical dispensing, administration, and imaging
US9943274B2 (en) 2004-11-09 2018-04-17 Spectrum Dynamics Medical Limited Radioimaging using low dose isotope
US8423125B2 (en) * 2004-11-09 2013-04-16 Spectrum Dynamics Llc Radioimaging
US9316743B2 (en) 2004-11-09 2016-04-19 Biosensors International Group, Ltd. System and method for radioactive emission measurement
US8615405B2 (en) 2004-11-09 2013-12-24 Biosensors International Group, Ltd. Imaging system customization using data from radiopharmaceutical-associated data carrier
WO2008059489A2 (en) 2006-11-13 2008-05-22 Spectrum Dynamics Llc Radioimaging applications of and novel formulations of teboroxime
US8837793B2 (en) 2005-07-19 2014-09-16 Biosensors International Group, Ltd. Reconstruction stabilizer and active vision
US8894974B2 (en) * 2006-05-11 2014-11-25 Spectrum Dynamics Llc Radiopharmaceuticals for diagnosis and therapy
EP2097438B1 (en) 2006-12-11 2015-08-26 Bracco Imaging S.p.A Fibrin binding peptide conjugates for diagnostic and therapeutic applications
WO2008075362A2 (en) * 2006-12-20 2008-06-26 Spectrum Dynamics Llc A method, a system, and an apparatus for using and processing multidimensional data
US8521253B2 (en) * 2007-10-29 2013-08-27 Spectrum Dynamics Llc Prostate imaging
EP2147684A1 (en) 2008-07-22 2010-01-27 Bracco Imaging S.p.A Diagnostic Agents Selective Against Metalloproteases
WO2010107832A1 (en) 2009-03-17 2010-09-23 Bracco Imaging Spa Lhrh-ii peptide analogs
US8338788B2 (en) 2009-07-29 2012-12-25 Spectrum Dynamics Llc Method and system of optimized volumetric imaging
CN102030797B (zh) * 2009-09-24 2013-03-20 中国科学院上海应用物理研究所 锝标记雌二醇类衍生物及其参照化合物及其制备方法、应用和其中间体
WO2015171543A1 (en) 2014-05-05 2015-11-12 California Institute Of Technology Mutant akt-specific capture agents, compositions, and methods of using and making
IL256833B2 (en) 2015-07-15 2025-07-01 California Inst Of Techn IL-17F-specific binding agents, compositions and methods of use and preparation
BR112018015143A2 (en) 2016-02-09 2018-12-18 Bracco Suisse Sa recombinant chimeric protein for selectin targeting
US20170319722A1 (en) 2016-04-04 2017-11-09 Indi Molecular, Inc. Cd8-specific capture agents, compositions, and methods of using and making
EP3519425B1 (en) 2016-09-29 2024-02-28 Indi Molecular, Inc. Compositions for detection, inhibition and imaging of indoleamine 2,3-dioxygenase 1 (ido1) and methods of making and using same
US11358982B2 (en) 2016-11-01 2022-06-14 Ohio State Innovation Foundation Methods for the iodination of biomolecules
EP3638687A1 (en) 2017-06-15 2020-04-22 Indi Molecular, Inc. Il-17f and il-17a-specific capture agents, compositions, and methods of using and making
CN107674098B (zh) * 2017-06-26 2021-12-07 中国医学科学院阜外医院 一类含芳基硼酸的99mTc配合物及其药盒配方和应用
WO2020097531A1 (en) 2018-11-08 2020-05-14 Indi Molecular, Inc. Theranostic capture agents, compositions, and methods of using and making
WO2020186091A1 (en) 2019-03-12 2020-09-17 Indi Molecular, Inc. Cross-linked epitopes and methods of use thereof
WO2020236969A1 (en) 2019-05-20 2020-11-26 Indi Molecular, Inc. Compositions and methods relating to detection, inhibition, and imaging of indoleamine 2,3-dioxygenase 1 (ido1)
EP3972646A4 (en) 2019-05-20 2023-06-14 Ohio State Innovation Foundation Apohemoglobin-haptoglobin complexes and methods of using thereof
US11414460B2 (en) 2019-07-19 2022-08-16 Institute For Systems Biology KRAS-specific capture agents, compositions, and methods of making and using
CN111377968B (zh) * 2020-03-09 2023-07-25 中国医学科学院阜外医院 一类含芳基硼酸的99mTc(Ⅲ)配合物及其药盒配方和应用
WO2022098745A1 (en) 2020-11-03 2022-05-12 Indi Molecular, Inc. Compositions, delivery systems, and methods useful in tumor therapy
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CN115197261B (zh) * 2022-07-06 2024-05-03 重庆医科大学 噁二氮杂硼衍生物的合成方法

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US3920995A (en) 1973-05-04 1975-11-18 Squibb & Sons Inc Radioactive material generator
US4431627A (en) * 1980-06-03 1984-02-14 Research Corporation Gamma-emitting receptor-binding 3-quinuclidinyl glycolates; methods of preparation thereof and imaging and assay methods utilizing same
US4705849A (en) * 1985-04-15 1987-11-10 E. R. Squibb & Sons, Inc. Boronic acid adducts of technetium-99m dioxime complexes
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CN1022562C (zh) * 1989-04-08 1993-10-27 中国人民解放军第二军医大学 一种消瘤药——甲硝唑氨酸的合成方法

Also Published As

Publication number Publication date
AU6938591A (en) 1991-07-25
KR910014385A (ko) 1991-08-31
US5387409A (en) 1995-02-07
FI910274A0 (fi) 1991-01-18
CN1120437A (zh) 1996-04-17
FI910274L (fi) 1991-07-19
MX24177A (es) 1993-12-01
IL96946A0 (en) 1992-03-29
IE910133A1 (en) 1991-07-31
EP0441491A1 (en) 1991-08-14
YU26691A (sh) 1994-05-10
AU7914794A (en) 1995-02-16
PT96518B (pt) 1998-06-30
FI910274A7 (fi) 1991-07-19
HU910155D0 (en) 1991-08-28
CN1111621A (zh) 1995-11-15
CA2034042C (en) 1999-08-17
JPH04212099A (ja) 1992-08-03
CN1054070A (zh) 1991-08-28
CN1034078C (zh) 1997-02-19
MY105482A (en) 1994-10-31
AU651076B2 (en) 1994-07-14
ZA91300B (en) 1991-11-27
NO910201L (no) 1991-07-19
CA2034042A1 (en) 1991-07-19
NZ236789A (en) 1995-03-28
KR100191568B1 (ko) 1999-06-15
PT96518A (pt) 1991-10-15
IL96946A (en) 1995-12-08

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