NO903314L - Fremgangsmaate for fremstilling av nye peptidaseinhibitorer - Google Patents
Fremgangsmaate for fremstilling av nye peptidaseinhibitorerInfo
- Publication number
- NO903314L NO903314L NO90903314A NO903314A NO903314L NO 903314 L NO903314 L NO 903314L NO 90903314 A NO90903314 A NO 90903314A NO 903314 A NO903314 A NO 903314A NO 903314 L NO903314 L NO 903314L
- Authority
- NO
- Norway
- Prior art keywords
- procedure
- preparation
- peptidase inhibitors
- new
- new peptidase
- Prior art date
Links
- 239000000137 peptide hydrolase inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/16—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/18—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by doubly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38562489A | 1989-07-26 | 1989-07-26 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO903314D0 NO903314D0 (no) | 1990-07-25 |
| NO903314L true NO903314L (no) | 1991-01-28 |
Family
ID=23522200
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO90903314A NO903314L (no) | 1989-07-26 | 1990-07-25 | Fremgangsmaate for fremstilling av nye peptidaseinhibitorer |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0410411A3 (no) |
| JP (1) | JPH0386852A (no) |
| KR (1) | KR910002896A (no) |
| CN (1) | CN1049016A (no) |
| AR (1) | AR248143A1 (no) |
| AU (1) | AU632836B2 (no) |
| CA (1) | CA2021660A1 (no) |
| FI (1) | FI94420C (no) |
| HU (1) | HU209931B (no) |
| IE (1) | IE902700A1 (no) |
| IL (1) | IL95168A (no) |
| NO (1) | NO903314L (no) |
| PT (1) | PT94811A (no) |
| ZA (1) | ZA905737B (no) |
Families Citing this family (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6008217A (en) * | 1995-12-20 | 1999-12-28 | Vertex Pharmaceuticals Incorporated | Inhibitors of interleukin-1β converting enzyme |
| US6204261B1 (en) | 1995-12-20 | 2001-03-20 | Vertex Pharmaceuticals Incorporated | Inhibitors of interleukin-1β Converting enzyme inhibitors |
| US5874424A (en) * | 1995-12-20 | 1999-02-23 | Vertex Pharmaceuticals Incorporated | Inhibitors of interleukin-1β converting enzyme |
| US5391705A (en) * | 1991-03-15 | 1995-02-21 | Merrell Dow Pharmaceuticals Inc. | Polyfluorinated tripeptide thrombin inhibitors |
| EP0503203A1 (en) * | 1991-03-15 | 1992-09-16 | Merrell Dow Pharmaceuticals Inc. | Novel thrombin inhibitors |
| JP3442075B2 (ja) * | 1991-05-23 | 2003-09-02 | メレルファーマス−テイカルズ インコーポレイテッド | 結合組織分解を防止するためのカテプシンｇとエラスターゼの阻害剤 |
| JP3228347B2 (ja) * | 1991-06-25 | 2001-11-12 | 三菱化学株式会社 | シクロプロペノン誘導体 |
| US5478811A (en) * | 1991-08-22 | 1995-12-26 | Merrell Dow Pharmaceuticals Inc. | Orally-active elastase inhibitors |
| US5714470A (en) * | 1991-08-22 | 1998-02-03 | Merrell Pharmaceuticals, Inc. | Orally-active elastase inhibitors |
| EP0644892A1 (en) * | 1992-06-12 | 1995-03-29 | Pfizer Inc. | Inhibitors of angiotensin i chymase(s) including human heart chymase |
| KR100244418B1 (ko) * | 1992-06-18 | 2000-02-01 | 슈테펜엘.네스비트 | 트롬빈 억제제 |
| WO1994028012A1 (en) * | 1993-05-28 | 1994-12-08 | Warner-Lambert Company | Hydroxamate inhibitors of endothelin converting enzyme |
| US5977074A (en) * | 1993-10-01 | 1999-11-02 | Merrell Pharmaceuticals, Inc. | Inhibitors of β-amyloid protein production |
| PT721449E (pt) * | 1993-10-01 | 2002-06-28 | Merrell Pharma Inc | Inibidores da producao da proteina beta-amiloide |
| US5436229A (en) * | 1994-03-04 | 1995-07-25 | Eli Lilly And Company | Bisulfite adducts of arginine aldehydes |
| US5707966A (en) * | 1994-03-04 | 1998-01-13 | Eli Lilly And Company | Antithrombotic agents |
| ZA951618B (en) * | 1994-03-04 | 1996-08-27 | Lilly Co Eli | Antithrombotic agents |
| US5885967A (en) * | 1994-03-04 | 1999-03-23 | Eli Lilly And Company | Antithrombotic agents |
| US5484772A (en) * | 1994-03-04 | 1996-01-16 | Eli Lilly And Company | Antithrombotic agents |
| CA2143533A1 (en) * | 1994-03-04 | 1995-09-05 | Kenneth D. Kurz | Antithrombotic agents |
| US5488037A (en) * | 1994-03-04 | 1996-01-30 | Eli Lilly And Company | Antithrombotic agents |
| US5726159A (en) * | 1994-03-04 | 1998-03-10 | Eli Lilly And Company | Antithrombotic agents |
| US5439888A (en) * | 1994-03-04 | 1995-08-08 | Eli Lilly And Company | Antithrombotic agents |
| US5705487A (en) * | 1994-03-04 | 1998-01-06 | Eli Lilly And Company | Antithrombotic agents |
| US5602101A (en) * | 1994-03-04 | 1997-02-11 | Eli Lilly And Company | Antithrombotic agents |
| DK0762887T3 (da) * | 1994-06-02 | 2002-01-14 | Merrell Pharma Inc | Acylerede enolderivater som prodrugs for elastase-hæmmere |
| ATE246708T1 (de) * | 1994-06-02 | 2003-08-15 | Aventis Pharma Inc | Elatase-inhibitoren |
| AU690986B2 (en) * | 1994-06-02 | 1998-05-07 | Merrell Pharmaceuticals Inc. | Perfluoroalkyl ketone inhibitors of elastase and processes for making the same |
| US5756466A (en) * | 1994-06-17 | 1998-05-26 | Vertex Pharmaceuticals, Inc. | Inhibitors of interleukin-1β converting enzyme |
| US6420522B1 (en) | 1995-06-05 | 2002-07-16 | Vertex Pharmaceuticals Incorporated | Inhibitors of interleukin-1β converting enzyme |
| US5847135A (en) * | 1994-06-17 | 1998-12-08 | Vertex Pharmaceuticals, Incorporated | Inhibitors of interleukin-1β converting enzyme |
| US5716929A (en) * | 1994-06-17 | 1998-02-10 | Vertex Pharmaceuticals, Inc. | Inhibitors of interleukin-1β converting enzyme |
| DE4421052A1 (de) | 1994-06-17 | 1995-12-21 | Basf Ag | Neue Thrombininhibitoren, ihre Herstellung und Verwendung |
| US5863902A (en) * | 1995-01-06 | 1999-01-26 | Sibia Neurosciences, Inc. | Methods of treating neurodegenerative disorders using protease inhibitors |
| US5804560A (en) * | 1995-01-06 | 1998-09-08 | Sibia Neurosciences, Inc. | Peptide and peptide analog protease inhibitors |
| MX9706069A (es) * | 1995-02-17 | 1997-10-31 | Basf Ag | Nuevos inhibidores de la trombina. |
| US5710130A (en) * | 1995-02-27 | 1998-01-20 | Eli Lilly And Company | Antithrombotic agents |
| US5914319A (en) * | 1995-02-27 | 1999-06-22 | Eli Lilly And Company | Antithrombotic agents |
| US6046169A (en) * | 1995-06-07 | 2000-04-04 | Cor Therapeutics, Inc. | Inhibitors of factor XA |
| US6022861A (en) * | 1995-06-07 | 2000-02-08 | Cor Therapeutics, Inc. | Ketoheterocyclic inhibitors of factor Xa |
| US5919765A (en) * | 1995-06-07 | 1999-07-06 | Cor Therapeutics, Inc. | Inhibitors of factor XA |
| US6211154B1 (en) | 1995-06-07 | 2001-04-03 | Cor Therapeutics, Inc. | Ketoheterocyclic inhibitors of factor Xa |
| US6069130A (en) | 1995-06-07 | 2000-05-30 | Cor Therapeutics, Inc. | Ketoheterocyclic inhibitors of factor Xa |
| US5721214A (en) * | 1995-06-07 | 1998-02-24 | Cor Therapeutics, Inc. | Inhibitors of factor Xa |
| US6069232A (en) * | 1995-10-02 | 2000-05-30 | Hoechst Marion Roussel, Inc. | Polyfluoroalkyl tryptophan tripeptide thrombin inhibitors |
| GB9524267D0 (en) * | 1995-11-28 | 1996-01-31 | Isis Innovation | Enzyme inhibitor and method |
| US5948886A (en) * | 1996-11-20 | 1999-09-07 | Hoechst Marion Roussel, Inc. | Acylated enol derivatives of α-ketoesters and α-ketoamides |
| US6172044B1 (en) | 1995-12-01 | 2001-01-09 | Aventis Pharmaceuticals Inc. | Acylated enol derivative of α-ketoesters and α-ketoamides |
| US5843904A (en) * | 1995-12-20 | 1998-12-01 | Vertex Pharmaceuticals, Inc. | Inhibitors of interleukin-1βconverting enzyme |
| US5739354A (en) * | 1996-03-26 | 1998-04-14 | Hoechst Marion Roussel, Inc. | Process for the preparation of N-methyl-D-phenylalanyl-N- 1- 3- (aminoiminomethyl)amino!propyl!-3,3-difluoro-2-oxohexyl!-L-prolinamide |
| US6245743B1 (en) | 1996-06-05 | 2001-06-12 | Cor Therapeutics, Inc. | Inhibitors of factor Xa |
| US6291640B1 (en) * | 1996-12-27 | 2001-09-18 | Boehringer Ingelheim Ltd. | Peptidomimetic inhibitors of the human cytomegalovirus protease |
| CA2317761A1 (en) | 1998-01-26 | 1999-07-29 | Basf Aktiengesellschaft | Thrombin inhibitors |
| ES2244178T3 (es) | 1998-03-09 | 2005-12-01 | Vertex Pharmaceuticals Incorporated | Derivados de 1,2-diazepan como inhibidores de la enzima convertidora de interleuquina-1 beta. |
| EP2261235A3 (en) | 1998-03-19 | 2011-04-20 | Vertex Pharmaceuticals Incorporated | Inhibitors of caspases |
| AUPP508798A0 (en) * | 1998-08-05 | 1998-08-27 | Biotech Australia Pty Limited | Method of treating psoriasis |
| AU2320300A (en) | 1999-01-28 | 2000-08-18 | Chugai Seiyaku Kabushiki Kaisha | Substituted phenethylamine derivatives |
| PE20011350A1 (es) | 2000-05-19 | 2002-01-15 | Vertex Pharma | PROFARMACO DE UN INHIBIDOR DE ENZIMA CONVERTIDORA DE INTERLEUCINA-1ß (ICE) |
| KR20040100835A (ko) | 2001-02-15 | 2004-12-02 | 킹 파머슈티칼스 리서치 앤드 디벨로프먼트 아이엔씨 | 안정된 제약및 갑상선 내분비 호르몬 구성물 및 그제조방법 |
| US7101569B2 (en) | 2001-08-14 | 2006-09-05 | Franz G Andrew | Methods of administering levothyroxine pharmaceutical compositions |
| EP2290098A1 (en) | 2002-01-28 | 2011-03-02 | Ambion, Inc. | Preparing crude biological extracts using protease, suitable for preparing cDNA |
| US7531570B2 (en) | 2004-05-27 | 2009-05-12 | Vertex Pharmaceuticals Incorporated | Treatment of diseases using ICE inhibitors |
| JP2007006315A (ja) | 2005-06-27 | 2007-01-11 | Konica Minolta Business Technologies Inc | 画像形成装置及び両面原稿の読み取り方法 |
| US7964350B1 (en) | 2007-05-18 | 2011-06-21 | Applied Biosystems, Llc | Sample preparation for in situ nucleic acid analysis |
| EP2955233A1 (en) * | 2008-12-19 | 2015-12-16 | Life Technologies Corporation | Proteinase K inhibitors, methods and compositions therefor |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0371179A1 (en) * | 1988-10-28 | 1990-06-06 | Merrell Dow Pharmaceuticals Inc. | Novel analogs of peptidase substrates |
| GB8910550D0 (en) * | 1989-05-08 | 1989-06-21 | Ici America Inc | Substituted amides |
| GB8910547D0 (en) * | 1989-05-08 | 1989-06-21 | Ici America Inc | Substituted ketones |
-
1990
- 1990-07-20 ZA ZA905737A patent/ZA905737B/xx unknown
- 1990-07-20 CA CA002021660A patent/CA2021660A1/en not_active Abandoned
- 1990-07-23 HU HU904585A patent/HU209931B/hu not_active IP Right Cessation
- 1990-07-23 IL IL9516890A patent/IL95168A/en not_active IP Right Cessation
- 1990-07-23 AU AU59742/90A patent/AU632836B2/en not_active Ceased
- 1990-07-24 PT PT94811A patent/PT94811A/pt not_active Application Discontinuation
- 1990-07-25 IE IE270090A patent/IE902700A1/en unknown
- 1990-07-25 JP JP2195110A patent/JPH0386852A/ja active Pending
- 1990-07-25 NO NO90903314A patent/NO903314L/no unknown
- 1990-07-25 CN CN90104871A patent/CN1049016A/zh active Pending
- 1990-07-25 EP EP19900114250 patent/EP0410411A3/en not_active Withdrawn
- 1990-07-26 AR AR90317471A patent/AR248143A1/es active
- 1990-07-26 KR KR1019900011366A patent/KR910002896A/ko not_active Ceased
- 1990-07-26 FI FI903737A patent/FI94420C/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU632836B2 (en) | 1993-01-14 |
| HU209931B (en) | 1994-12-28 |
| CA2021660A1 (en) | 1991-01-27 |
| FI903737A0 (fi) | 1990-07-26 |
| JPH0386852A (ja) | 1991-04-11 |
| FI94420C (fi) | 1995-09-11 |
| EP0410411A2 (en) | 1991-01-30 |
| CN1049016A (zh) | 1991-02-06 |
| HU904585D0 (en) | 1990-12-28 |
| PT94811A (pt) | 1991-03-20 |
| IE902700A1 (en) | 1991-02-27 |
| FI94420B (fi) | 1995-05-31 |
| EP0410411A3 (en) | 1991-12-27 |
| AU5974290A (en) | 1991-01-31 |
| KR910002896A (ko) | 1991-02-26 |
| AR248143A1 (es) | 1995-06-30 |
| IL95168A (en) | 1995-10-31 |
| HUT54177A (en) | 1991-01-28 |
| ZA905737B (en) | 1991-05-29 |
| NO903314D0 (no) | 1990-07-25 |
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