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NO904114L - Pyrimidin-4,6-dikarboksylsyrediamider samt fremgangsmaate for fremstilling derav. - Google Patents

Pyrimidin-4,6-dikarboksylsyrediamider samt fremgangsmaate for fremstilling derav.

Info

Publication number
NO904114L
NO904114L NO90904114A NO904114A NO904114L NO 904114 L NO904114 L NO 904114L NO 90904114 A NO90904114 A NO 90904114A NO 904114 A NO904114 A NO 904114A NO 904114 L NO904114 L NO 904114L
Authority
NO
Norway
Prior art keywords
pyrimidine
diamids
procedures
preparing
dicarboxylic acid
Prior art date
Application number
NO90904114A
Other languages
English (en)
Other versions
NO904114D0 (no
Inventor
Ekkehard Baader
Martin Bickel
Volkmar Guenzler-Pukall
Stephan Henke
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO904114D0 publication Critical patent/NO904114D0/no
Publication of NO904114L publication Critical patent/NO904114L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cephalosporin Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Dental Preparations (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO90904114A 1989-09-21 1990-09-20 Pyrimidin-4,6-dikarboksylsyrediamider samt fremgangsmaate for fremstilling derav. NO904114L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3931432A DE3931432A1 (de) 1989-09-21 1989-09-21 Pyrimidin-4,6-dicarbonsaeurediamide, verfahren zu deren herstellung sowie verwendung derselben sowie arzneimittel auf basis dieser verbindungen

Publications (2)

Publication Number Publication Date
NO904114D0 NO904114D0 (no) 1990-09-20
NO904114L true NO904114L (no) 1991-03-22

Family

ID=6389833

Family Applications (1)

Application Number Title Priority Date Filing Date
NO90904114A NO904114L (no) 1989-09-21 1990-09-20 Pyrimidin-4,6-dikarboksylsyrediamider samt fremgangsmaate for fremstilling derav.

Country Status (22)

Country Link
US (1) US5130317A (no)
EP (1) EP0418797B1 (no)
JP (1) JPH03240776A (no)
KR (1) KR910006241A (no)
AT (1) ATE110369T1 (no)
AU (2) AU633142B2 (no)
CA (1) CA2025799A1 (no)
CZ (1) CZ458390A3 (no)
DD (1) DD295835A5 (no)
DE (2) DE3931432A1 (no)
DK (1) DK0418797T3 (no)
ES (1) ES2062239T3 (no)
FI (1) FI904604A7 (no)
HU (2) HU207853B (no)
IE (1) IE903403A1 (no)
IL (1) IL95740A (no)
LV (1) LV10441A (no)
NO (1) NO904114L (no)
PL (1) PL164989B1 (no)
PT (1) PT95375A (no)
RU (1) RU1836359C (no)
ZA (1) ZA907535B (no)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3930696A1 (de) * 1989-09-14 1991-03-28 Hoechst Ag Gallensaeurederivate, verfahren zu ihrer herstellung, verwendung als arzneimittel
ATE178666T1 (de) * 1992-01-13 1999-04-15 Hercules Inc Wärmeverbindbare fasern für wiederstandsfähige vliesstoffe
SG50447A1 (en) 1993-06-24 1998-07-20 Hercules Inc Skin-core high thermal bond strength fiber on melt spin system
IL116430A (en) * 1994-12-19 2000-08-13 Hercules Inc Process for preparing a polypropylene containing fiber
US5968965A (en) * 1996-01-30 1999-10-19 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
DOP2002000332A (es) 2001-02-14 2002-08-30 Warner Lambert Co Inhibidores de piridina de metaloproteinasas de la matriz
DOP2002000333A (es) 2001-02-14 2002-09-30 Warner Lambert Co Derivados de acido isoftalico como inhibidores de metaloproteinasas de la matriz
WO2002064571A1 (en) * 2001-02-14 2002-08-22 Warner-Lambert Company Llc Pyrimidine matrix metalloproteinase inhibitors
US6924276B2 (en) 2001-09-10 2005-08-02 Warner-Lambert Company Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors
MXPA04002537A (es) 2001-10-12 2004-05-31 Warner Lambert Co Alquinos como inhibidores de metaloproteinasa de matriz.
US6933298B2 (en) 2001-12-08 2005-08-23 Aventis Pharma Deutschland Gmbh Pyridine-2,4-dicarboxylic acid diamides and pyrimidine-4,6-dicarboxylic acid diamides and the use thereof for selectively inhibiting collagenases
DE10160357A1 (de) * 2001-12-08 2003-06-18 Aventis Pharma Gmbh Verwendung von Pyridin-2,4-dicarbonsäurediamiden und Pyrimidin-4,6-dicarbonsäurediamiden zur selektiven Inhibierung von Kollagenasen
CA2494014A1 (en) * 2002-08-13 2004-02-19 Warner-Lambert Company Llc Monocyclic derivatives as matrix metalloproteinase inhibitors
PA8578101A1 (es) * 2002-08-13 2004-05-07 Warner Lambert Co Derivados de heterobiarilo como inhibidores de metaloproteinasa de la matriz
AU2003249539A1 (en) * 2002-08-13 2004-02-25 Warner-Lambert Company Llc Cyclic compounds containing zinc binding groups as matrix metalloproteinase inhibitors
DE60313350T2 (de) * 2002-08-13 2008-01-03 Warner-Lambert Company Llc Pyrimidin-2,4-dion-derivate als matrix-metalloproteinase-hemmer
EP1394159A1 (fr) * 2002-08-13 2004-03-03 Warner-Lambert Company LLC Nouveaux dérivés de thiophène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent
US7166609B2 (en) * 2002-11-02 2007-01-23 Sanofi-Aventis Deutschland Gmbh Pyrimidine-4,6-dicarboxylic acid diamides for selectively inhibiting collagenases
PT1560815E (pt) * 2002-11-02 2008-04-07 Sanofi Aventis Deutschland Novas diamidas do ácido pirimidino-4,6-dicarboxílico para a inibição selectiva de colagenases
DE10251019A1 (de) * 2002-11-02 2004-05-19 Aventis Pharma Deutschland Gmbh Neue Pyrimidin-4,6-dicarbonsäurediamide zur selektiven Inhibierung von Kollagenasen
DE10300017A1 (de) * 2003-01-03 2004-07-15 Aventis Pharma Deutschland Gmbh Selektive MMP 13 Inhibitoren
US20050004111A1 (en) * 2003-01-03 2005-01-06 Aventis Pharma Deutschland Gmbh Selective MMP-13 inhibitors
WO2005016926A1 (en) * 2003-08-19 2005-02-24 Warner-Lambert Company Llc Pyrido [3,4-d] pyrimidine derivatives as matrix metalloproteinase-13 inhibitors
CA2635580A1 (en) * 2005-12-30 2007-07-12 Alantos Pharmaceuticals Holding, Inc. Substituted bis-amide metalloprotease inhibitors
EA020548B1 (ru) 2008-12-19 2014-12-30 Бёрингер Ингельхайм Интернациональ Гмбх Циклические пиримидин-4-карбоксамиды в качестве антагонистов рецептора ccr2, предназначенные для лечения воспаления, астмы и хозл

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0112617B1 (en) * 1982-11-04 1986-12-30 Imperial Chemical Industries Plc Process for the extraction of metal values and novel metal extractants
US4962109A (en) * 1985-12-23 1990-10-09 Imperial Chemical Industries Plc Insecticidally and acaricidally active pyrimidine esters and intermediates therefor
WO1988000237A1 (en) * 1986-06-27 1988-01-14 Damon Biotech, Inc. Covalent membranes
DE3703959A1 (de) * 1987-02-10 1988-08-18 Hoechst Ag Pyridin-2,4- und 2,5-dicarbonsaeureamide, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen
AU4951690A (en) * 1988-12-30 1990-08-01 David M. Anderson Stabilized microporous materials and hydrogel materials

Also Published As

Publication number Publication date
ATE110369T1 (de) 1994-09-15
AU635326B2 (en) 1993-03-18
HU207853B (en) 1993-06-28
EP0418797A2 (de) 1991-03-27
IL95740A0 (en) 1991-06-30
HU906007D0 (en) 1991-03-28
KR910006241A (ko) 1991-04-27
AU6269990A (en) 1991-04-11
EP0418797A3 (en) 1991-05-08
ZA907535B (en) 1991-06-26
ES2062239T3 (es) 1994-12-16
IE903403A1 (en) 1991-04-10
DK0418797T3 (da) 1995-01-02
LV10441A (lv) 1995-02-20
AU6269890A (en) 1991-04-11
HU210822A9 (en) 1995-08-28
NO904114D0 (no) 1990-09-20
FI904604A0 (fi) 1990-09-19
HUT55002A (en) 1991-04-29
AU633142B2 (en) 1993-01-21
PT95375A (pt) 1991-05-22
CA2025799A1 (en) 1991-03-22
CZ458390A3 (en) 1995-01-18
FI904604A7 (fi) 1991-03-22
DE3931432A1 (de) 1991-04-04
PL164989B1 (en) 1994-10-31
IL95740A (en) 1994-07-31
US5130317A (en) 1992-07-14
EP0418797B1 (de) 1994-08-24
JPH03240776A (ja) 1991-10-28
DE59006893D1 (de) 1994-09-29
RU1836359C (ru) 1993-08-23
DD295835A5 (de) 1991-11-14
PL286972A1 (en) 1991-10-21

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