NO892861L - Fremgangsmaate ved syntese av levodopa. - Google Patents
Fremgangsmaate ved syntese av levodopa.Info
- Publication number
- NO892861L NO892861L NO89892861A NO892861A NO892861L NO 892861 L NO892861 L NO 892861L NO 89892861 A NO89892861 A NO 89892861A NO 892861 A NO892861 A NO 892861A NO 892861 L NO892861 L NO 892861L
- Authority
- NO
- Norway
- Prior art keywords
- levodopa
- synthesis
- procedure
- Prior art date
Links
- WTDRDQBEARUVNC-LURJTMIESA-N L-DOPA Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-LURJTMIESA-N 0.000 title 1
- WTDRDQBEARUVNC-UHFFFAOYSA-N L-Dopa Natural products OC(=O)C(N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-UHFFFAOYSA-N 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 229960004502 levodopa Drugs 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/30—Preparation of optical isomers
- C07C227/34—Preparation of optical isomers by separation of optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
- C07C255/42—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being further bound to other hetero atoms
- C07C255/43—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being further bound to other hetero atoms the carbon skeleton being further substituted by singly-bound oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8821322A IT1226902B (it) | 1988-07-12 | 1988-07-12 | Processo per la sintesi del levodopa |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO892861D0 NO892861D0 (no) | 1989-07-11 |
| NO892861L true NO892861L (no) | 1990-01-15 |
| NO174293B NO174293B (no) | 1994-01-03 |
| NO174293C NO174293C (no) | 1994-04-13 |
Family
ID=11180092
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO892861A NO174293C (no) | 1988-07-12 | 1989-07-11 | Fremgangsmåte og mellomprodukter ved syntese av levodopa |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4962223A (no) |
| EP (1) | EP0357565B1 (no) |
| JP (1) | JP2507069B2 (no) |
| KR (1) | KR960004185B1 (no) |
| AR (1) | AR248267A1 (no) |
| AT (1) | ATE111439T1 (no) |
| AU (1) | AU615083B2 (no) |
| CA (1) | CA1338672C (no) |
| DD (1) | DD284674A5 (no) |
| DE (1) | DE68918207T2 (no) |
| DK (1) | DK172106B1 (no) |
| ES (1) | ES2063837T3 (no) |
| FI (1) | FI101534B1 (no) |
| HU (1) | HU203318B (no) |
| IE (1) | IE65956B1 (no) |
| IL (1) | IL90844A0 (no) |
| IT (1) | IT1226902B (no) |
| NO (1) | NO174293C (no) |
| NZ (1) | NZ229910A (no) |
| PL (1) | PL160103B1 (no) |
| PT (1) | PT91144B (no) |
| YU (1) | YU47907B (no) |
| ZA (1) | ZA895255B (no) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5459145A (en) * | 1988-01-19 | 1995-10-17 | Pfizer Inc. | Calcium independent camp phosphodiesterase inhibitor antidepressant |
| IT1226903B (it) * | 1988-07-12 | 1991-02-21 | Mini Ricerca Scient Tecnolog | Processo per la sintesi di aminoacidi otticamente attivi |
| US5395935A (en) * | 1992-05-08 | 1995-03-07 | Pfizer Inc. | Endo-bicyclo[2.2.1]heptan-2-ol and derived pharmaceutical agents |
| DE19502967A1 (de) * | 1995-01-31 | 1996-08-01 | Basf Ag | Verfahren zur Racemattrennung von 2-Aryl-2-omega-alkylaminoalkannitrilen |
| JP3634207B2 (ja) * | 1999-09-14 | 2005-03-30 | 独立行政法人科学技術振興機構 | 光学活性なα−アミノニトリル並びにα−アミノ酸類の製造方法 |
| US20040002615A1 (en) * | 2002-06-28 | 2004-01-01 | Allen David Robert | Preparation of chiral amino-nitriles |
| US20040180086A1 (en) * | 2002-10-11 | 2004-09-16 | Zebunnissa Ramtoola | Gastro-retentive levodopa delivery form |
| DE10261807A1 (de) | 2002-12-19 | 2004-07-01 | Turicum Drug Development Ag | Deuterierte Catecholaminderivate sowie diese Verbindungen enthaltende Arzneimittel |
| WO2004069146A2 (en) * | 2003-02-07 | 2004-08-19 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | L-dopa amide derivatives and uses thereof |
| UA97795C2 (uk) | 2006-02-17 | 2012-03-26 | Бьордз Фарма Гмбх Бероліна Інновейтів Ресерч Унд Девелопмент Сервісіз | Дейтеровані похідні катехоламіну і медикаменти, що містять згадані сполуки |
| US10258585B2 (en) | 2014-03-13 | 2019-04-16 | Neuroderm, Ltd. | DOPA decarboxylase inhibitor compositions |
| HRP20201948T1 (hr) | 2014-03-13 | 2021-01-22 | Neuroderm Ltd | Pripravci inhibitora dopa-dekarbokilaze |
| DK3856196T3 (da) | 2018-09-28 | 2024-02-19 | Univ Griffith | Phenylpropionsyrederivater til modulation af patogen aktivitet |
| US11331293B1 (en) | 2020-11-17 | 2022-05-17 | Neuroderm, Ltd. | Method for treatment of Parkinson's disease |
| US11213502B1 (en) | 2020-11-17 | 2022-01-04 | Neuroderm, Ltd. | Method for treatment of parkinson's disease |
| US11844754B2 (en) | 2020-11-17 | 2023-12-19 | Neuroderm, Ltd. | Methods for treatment of Parkinson's disease |
| US12161612B2 (en) | 2023-04-14 | 2024-12-10 | Neuroderm, Ltd. | Methods and compositions for reducing symptoms of Parkinson's disease |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA504449A (en) * | 1954-07-20 | C. Britton Edgar | Alpha-amino-beta-alkoxy-butyronitriles and method of making same | |
| BE638485A (no) * | 1962-10-11 | |||
| US3845076A (en) * | 1971-04-20 | 1974-10-29 | Sagami Chem Res | Method of preparing aldehydes |
| JPS4920305A (no) * | 1972-06-21 | 1974-02-22 | ||
| HU165026B (no) * | 1972-08-11 | 1974-06-28 | ||
| US4072698A (en) * | 1976-12-02 | 1978-02-07 | The Upjohn Company | Resolution of aminonitriles |
| YU93877A (en) * | 1977-04-08 | 1982-06-30 | Krka | Process for the resolution of racemic alpha-aminonitrils |
| IL59048A (en) * | 1979-12-27 | 1984-01-31 | Plantex Ltd | Process for the preparation of alpha-amino-3-phenyl-propionitriles and novel benzylidene amino acetonitriles as intermediates therefor |
| DE3002543A1 (de) * | 1980-01-25 | 1981-07-30 | Basf Ag, 6700 Ludwigshafen | 4-tert.-butoxyphenylglycinnitril sowie verfahren zur herstellung von d-(-)- und l-(+)-4-hydroxyphenylglycin |
| JPS56115749A (en) * | 1980-02-18 | 1981-09-11 | Sagami Chem Res Center | Dopa derivative |
| JPS61275253A (ja) * | 1985-05-30 | 1986-12-05 | Nippon Kayaku Co Ltd | ３−（３，４−ジヒドロキシフエニル）−２−メチルアラニンの製造法 |
| FR2614626B1 (fr) * | 1987-04-30 | 1989-07-21 | Ranoux Claude | Conteneur pour fecondation des ovocytes et replacement des embryons chez l'homme et l'animal |
-
1988
- 1988-07-12 IT IT8821322A patent/IT1226902B/it active
-
1989
- 1989-07-03 US US07/375,131 patent/US4962223A/en not_active Expired - Fee Related
- 1989-07-03 IL IL90844A patent/IL90844A0/xx not_active IP Right Cessation
- 1989-07-07 ES ES89830316T patent/ES2063837T3/es not_active Expired - Lifetime
- 1989-07-07 AT AT89830316T patent/ATE111439T1/de not_active IP Right Cessation
- 1989-07-07 DE DE68918207T patent/DE68918207T2/de not_active Expired - Fee Related
- 1989-07-07 EP EP89830316A patent/EP0357565B1/en not_active Expired - Lifetime
- 1989-07-11 ZA ZA895255A patent/ZA895255B/xx unknown
- 1989-07-11 DD DD89330685A patent/DD284674A5/de not_active IP Right Cessation
- 1989-07-11 HU HU893486A patent/HU203318B/hu not_active IP Right Cessation
- 1989-07-11 NZ NZ229910A patent/NZ229910A/en unknown
- 1989-07-11 IE IE222789A patent/IE65956B1/en not_active IP Right Cessation
- 1989-07-11 FI FI893368A patent/FI101534B1/fi not_active IP Right Cessation
- 1989-07-11 NO NO892861A patent/NO174293C/no not_active IP Right Cessation
- 1989-07-11 PL PL89280528A patent/PL160103B1/pl unknown
- 1989-07-11 DK DK342489A patent/DK172106B1/da not_active IP Right Cessation
- 1989-07-11 AR AR89314355A patent/AR248267A1/es active
- 1989-07-12 JP JP1180152A patent/JP2507069B2/ja not_active Expired - Lifetime
- 1989-07-12 CA CA000605420A patent/CA1338672C/en not_active Expired - Fee Related
- 1989-07-12 KR KR1019890009905A patent/KR960004185B1/ko not_active Expired - Fee Related
- 1989-07-12 AU AU38057/89A patent/AU615083B2/en not_active Ceased
- 1989-07-12 PT PT91144A patent/PT91144B/pt not_active IP Right Cessation
- 1989-07-12 YU YU139989A patent/YU47907B/sh unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |
Free format text: LAPSED IN JANUARY 2001 |