NO883229L - Nye benzimidazolderivater, fremgangsmaate for deres fremstilling og farmasoeytisk preparat inneholdende slike derivater. - Google Patents

Nye benzimidazolderivater, fremgangsmaate for deres fremstilling og farmasoeytisk preparat inneholdende slike derivater.

Info

Publication number: NO883229L
Authority: NO; Norway
Prior art keywords: derivatives; procedures; new; preparation; benzimidazold
Prior art date: 1986-11-21

Application number

NO88883229A

Other languages

English (en)

Other versions

NO173998B (no

NO883229D0 (no

NO173998C (no

Inventor

Tomas Boerje Alminger

Rolf Axel Bergman

Hans Bundegaard

Per Lennart Lindberg

Gunnel Elisabeth Sunden

Original Assignee

Haessle Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-11-21

Filing date

1988-07-20

Publication date

1988-09-16

1986-11-21 Priority claimed from SE8604998A external-priority patent/SE8604998D0/xx

1986-12-23 Priority claimed from SE8605551A external-priority patent/SE8605551D0/xx

1987-10-16 Priority claimed from SE8704049A external-priority patent/SE8704049D0/xx

1988-07-20 Application filed by Haessle Ab filed Critical Haessle Ab

1988-07-20 Publication of NO883229D0 publication Critical patent/NO883229D0/no

1988-09-16 Publication of NO883229L publication Critical patent/NO883229L/no

1993-11-22 Publication of NO173998B publication Critical patent/NO173998B/no

1994-03-02 Publication of NO173998C publication Critical patent/NO173998C/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

NO883229A 1986-11-21 1988-07-20 Analogifremgangsmaate for fremstilling av terapeutisk aktive benzimidazolderivater NO173998C (no)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
SE8604998A SE8604998D0 (sv)	1986-11-21	1986-11-21	Novel pharmacological compounds
SE8605551A SE8605551D0 (sv)	1986-12-23	1986-12-23	Novel pharmacological compounds
SE8704049A SE8704049D0 (sv)	1987-10-16	1987-10-16	Novel pharmacological compounds
PCT/SE1987/000546 WO1988003921A1 (en)	1986-11-21	1987-11-20	New benzimidazole derivatives a process for production thereof and a pharmaceutical composition containing the same

Publications (4)

Publication Number	Publication Date
NO883229D0 NO883229D0 (no)	1988-07-20
NO883229L true NO883229L (no)	1988-09-16
NO173998B NO173998B (no)	1993-11-22
NO173998C NO173998C (no)	1994-03-02

Family

ID=27355365

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO883229A NO173998C (no)	1986-11-21	1988-07-20	Analogifremgangsmaate for fremstilling av terapeutisk aktive benzimidazolderivater

Country Status (24)

Country	Link
EP (3)	EP0332647A1 (no)
JP (1)	JPH02500744A (no)
KR (1)	KR890700125A (no)
AT (1)	ATE84032T1 (no)
AU (1)	AU612129B2 (no)
DE (1)	DE3783356T2 (no)
DK (1)	DK365488D0 (no)
EG (1)	EG18379A (no)
ES (1)	ES2052603T3 (no)
FI (1)	FI892454A7 (no)
GR (1)	GR3007385T3 (no)
HU (1)	HU204814B (no)
IE (2)	IE940326L (no)
IL (1)	IL84504A (no)
IS (1)	IS1565B (no)
LV (1)	LV10954B (no)
MY (1)	MY101784A (no)
NO (1)	NO173998C (no)
NZ (2)	NZ222495A (no)
PL (1)	PL157655B1 (no)
PT (1)	PT86186B (no)
RU (1)	RU2062778C1 (no)
WO (1)	WO1988003921A1 (no)
YU (1)	YU47116B (no)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE8801907D0 (sv) *	1988-05-20	1988-05-20	Haessle Ab	Novel pharmacological compounds
WO1990003373A1 (fr) *	1988-09-20	1990-04-05	Hisamitsu Pharmaceutical Co., Inc.	NOUVEAUX DERIVES DE DIBENZ[b,e]OXEPINE
EG19302A (en) *	1988-12-22	1994-11-30	Haessle Ab	Compound with gastric acid inhibitory effect and process for its preparation
SE8804629D0 (sv) *	1988-12-22	1988-12-22	Ab Haessle	New therapeutically active compounds
US5049674A (en) *	1989-12-20	1991-09-17	Aktiebolaget Hassle	Therapeutically active fluoro substituted benzimidazoles
US4965269A (en) *	1989-12-20	1990-10-23	Ab Hassle	Therapeutically active chloro substituted benzimidazoles
US5274099A (en) *	1989-12-20	1993-12-28	Aktiebolaget Hassle	Therapeutically active fluoro substituted benzimidazoles
SE9002206D0 (sv)	1990-06-20	1990-06-20	Haessle Ab	New compounds
ATE184602T1 (de) *	1990-06-20	1999-10-15	Astra Ab	Dialkoxypyridinylbenzimidazolderivate, verfahren zur herstellung und ihre pharmazeutische verwendung
EP0481764B1 (en) *	1990-10-17	2000-03-29	Takeda Chemical Industries, Ltd.	Pyridine derivatives, their production and use
SE9103776D0 (sv) *	1991-12-19	1991-12-19	Astra Ab	New compounds
US5376665A (en) *	1992-05-21	1994-12-27	Otsuka Pharmaceutical Factory, Inc.	Phosphonic diester derivatives
AU6556894A (en) *	1993-05-18	1994-12-12	Upjohn Company, The	Bisphosphonate esters for treating gastric disorders
US6875872B1 (en)	1993-05-28	2005-04-05	Astrazeneca	Compounds
SE508669C2 (sv) *	1996-04-26	1998-10-26	Astra Ab	Nytt förfarande
AU6551198A (en) *	1997-05-30	1998-12-30	Dr. Reddy's Research Foundation	Novel benzimidazole derivatives as antiulcer agents, process for their preparation and pharmaceutical compositions containing them
EP1051181B1 (en) *	1997-12-31	2004-03-17	The University Of Kansas	Water soluble prodrugs of tertiary amine containing drugs and methods of making thereof
ZA9810765B (en) *	1998-05-28	1999-08-06	Ranbaxy Lab Ltd	Stable oral pharmaceutical composition containing a substituted pyridylsulfinyl benzimidazole.
AU2583901A (en)	1999-12-17	2001-06-25	Ariad Pharmaceuticals, Inc.	Proton pump inhibitors
US20040039027A1 (en) *	2000-10-12	2004-02-26	Keiji Kamiyama	Benzimidazole compounds, process for producing the same and use thereof
WO2003027098A1 (en) *	2001-09-25	2003-04-03	Takeda Chemical Industries, Ltd.	Benzimidazole compound, process for producing the same, and use thereof
KR100822981B1 (ko) *	2002-07-19	2008-04-16	윈스턴 파마슈티컬즈, 엘엘씨	벤즈이미다졸 유도체 및 이들의 프로톤 펌프 억제제의프로드럭으로서의 이용
GB0400781D0 (en) *	2004-01-14	2004-02-18	Novartis Ag	Organic compounds
PT1781619E (pt) *	2004-08-27	2011-11-04	Esteve Labor Dr	Inibidores do recetor sigma
WO2007014846A1 (en) *	2005-07-28	2007-02-08	Intervet International B.V.	Novel benzimidazole (thio) carbamates with antiparasitic activity and the synthesis thereof
CA3000985C (en)	2014-10-14	2023-01-31	The Board Of Trustees Of The Leland Stanford Junior University	Method for treating neurodegenerative diseases
EP3390367B1 (en)	2015-12-15	2020-09-09	The Board of Trustees of the Leland Stanford Junior University	Method for preventing and/or treating aging-associated cognitive impairment and neuroinflammation
SG11202101285YA (en)	2018-08-06	2021-03-30	Univ Leland Stanford Junior	2-arylbenzimidazoles as ppargc1a activators for treating neurodegenerative diseases
JP7409383B2 (ja) *	2019-08-20	2024-01-09	小野薬品工業株式会社	Ｓ１ｐ５受容体作動活性を有する化合物の塩および結晶形

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE418966B (sv)	1974-02-18	1981-07-06	Haessle Ab	Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv)	1974-05-16	1981-01-26	Haessle Ab	Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (no)	1977-09-19	1981-07-25	Hoffmann La Roche
SE7804231L (sv)	1978-04-14	1979-10-15	Haessle Ab	Magsyrasekretionsmedel
JPS5836312B2 (ja) *	1978-08-21	1983-08-08	日本電信電話株式会社	通信用平衡ケ−ブル線路の障害位置測定方式
JPS5687818A (en) *	1979-12-19	1981-07-16	Ishikawajima Harima Heavy Ind Co Ltd	Reflex type position detector
US4359465A (en)	1980-07-28	1982-11-16	The Upjohn Company	Methods for treating gastrointestinal inflammation
CH644116A5 (de)	1980-08-21	1984-07-13	Hoffmann La Roche	Imidazolderivate.
JPS57137860A (en) *	1981-02-20	1982-08-25	Sumitomo Electric Ind Ltd	Optical tachometer
JPS5999597A (ja) *	1982-11-30	1984-06-08	株式会社東芝	光学測定装置
SE8300736D0 (sv) *	1983-02-11	1983-02-11	Haessle Ab	Novel pharmacologically active compounds
JPS6020051U (ja) *	1983-07-19	1985-02-12	三洋電機株式会社	カセツト収納装置
AU568441B2 (en) *	1984-09-24	1987-12-24	Upjohn Company, The	2-(pyridylalkenesulfinyl) benzimidazole derivatives
IL76839A (en) *	1984-10-31	1988-08-31	Byk Gulden Lomberg Chem Fab	Picoline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
SE8505112D0 (sv) *	1985-10-29	1985-10-29	Haessle Ab	Novel pharmacological compounds

1987
- 1987-11-10 NZ NZ222495A patent/NZ222495A/en unknown
- 1987-11-10 NZ NZ234564A patent/NZ234564A/en unknown
- 1987-11-17 IL IL8450487A patent/IL84504A/en not_active IP Right Cessation
- 1987-11-19 EG EG669/87A patent/EG18379A/xx active
- 1987-11-19 IE IE940326A patent/IE940326L/xx unknown
- 1987-11-19 IE IE312587A patent/IE61178B1/en not_active IP Right Cessation
- 1987-11-19 IS IS3284A patent/IS1565B/is unknown
- 1987-11-20 PT PT86186A patent/PT86186B/pt not_active IP Right Cessation
- 1987-11-20 FI FI892454A patent/FI892454A7/fi not_active Application Discontinuation
- 1987-11-20 AT AT87850362T patent/ATE84032T1/de not_active IP Right Cessation
- 1987-11-20 AU AU83302/87A patent/AU612129B2/en not_active Ceased
- 1987-11-20 WO PCT/SE1987/000546 patent/WO1988003921A1/en not_active Ceased
- 1987-11-20 RU SU874614294A patent/RU2062778C1/ru active
- 1987-11-20 YU YU211087A patent/YU47116B/sh unknown
- 1987-11-20 MY MYPI87003072A patent/MY101784A/en unknown
- 1987-11-20 DE DE8787850362T patent/DE3783356T2/de not_active Expired - Fee Related
- 1987-11-20 EP EP87908006A patent/EP0332647A1/en active Pending
- 1987-11-20 EP EP87850362A patent/EP0279149B1/en not_active Expired - Lifetime
- 1987-11-20 JP JP63500255A patent/JPH02500744A/ja active Pending
- 1987-11-20 HU HU876196A patent/HU204814B/hu not_active IP Right Cessation
- 1987-11-20 EP EP92108817A patent/EP0510719A1/en not_active Withdrawn
- 1987-11-20 ES ES87850362T patent/ES2052603T3/es not_active Expired - Lifetime
- 1987-11-21 PL PL1987268927A patent/PL157655B1/pl unknown
1988
- 1988-07-01 DK DK365488A patent/DK365488D0/da not_active Application Discontinuation
- 1988-07-20 NO NO883229A patent/NO173998C/no unknown
- 1988-07-20 KR KR1019880700859A patent/KR890700125A/ko not_active Ceased
1993
- 1993-03-16 GR GR930400598T patent/GR3007385T3/el unknown
- 1993-12-23 LV LVP-93-1371A patent/LV10954B/en unknown

Also Published As

Publication number	Publication date
PT86186A (en)	1987-12-01
GR3007385T3 (no)	1993-07-30
LV10954A (lv)	1995-12-20
IE873125L (en)	1988-05-21
KR890700125A (ko)	1989-03-02
JPH02500744A (ja)	1990-03-15
PL157655B1 (pl)	1992-06-30
EP0279149A2 (en)	1988-08-24
IS1565B (is)	1994-12-13
YU47116B (sh)	1994-12-28
EG18379A (en)	1992-11-30
MY101784A (en)	1992-01-17
IL84504A (en)	1994-10-07
EP0279149A3 (en)	1988-08-31
ES2052603T3 (es)	1994-07-16
NO173998B (no)	1993-11-22
DK365488A (da)	1988-07-01
PL268927A1 (en)	1989-01-23
IE940326L (en)	1988-05-21
WO1988003921A1 (en)	1988-06-02
ATE84032T1 (de)	1993-01-15
IE61178B1 (en)	1994-10-05
EP0510719A1 (en)	1992-10-28
HUT51269A (en)	1990-04-28
NZ222495A (en)	1991-04-26
NZ234564A (en)	1991-04-26
YU211087A (en)	1988-12-31
NO883229D0 (no)	1988-07-20
AU8330287A (en)	1988-06-16
RU2062778C1 (ru)	1996-06-27
DE3783356D1 (de)	1993-02-11
HU204814B (en)	1992-02-28
FI892454L (fi)	1989-05-19
IS3284A7 (is)	1988-05-22
LV10954B (en)	1996-08-20
DK365488D0 (da)	1988-07-01
EP0332647A1 (en)	1989-09-20
NO173998C (no)	1994-03-02
FI892454A0 (fi)	1989-05-19
DE3783356T2 (de)	1993-04-15
EP0279149B1 (en)	1992-12-30
PT86186B (pt)	1990-08-31
AU612129B2 (en)	1991-07-04
FI892454A7 (fi)	1989-05-19

Publication	Publication Date	Title
NO883229D0 (no)	1988-07-20	Nye benzimidazolderivater, fremgangsmaate for deres fremstilling og farmasoeytisk preparat inneholdende slike derivater.
FI872864A0 (fi)	1987-06-29	Menetelmä farmaseuttisesti aktiivisten bentsimidatsolijohdannaisten valmistamiseksi
BG60102B2 (bg)	1993-10-29	Метод за получаване на 5-флуор-2(((4-циклопропил- метокси-2-пиридинил)метил)тионил)-1н-бензимидазол
SE8300736D0 (sv)	1983-02-11	Novel pharmacologically active compounds
DE3583916D1 (de)	1991-10-02	Waessrige arzneiformulierungen des piroxicammonohydrats.
SE8404065D0 (sv)	1984-08-10	Novel biologically active compounds
DK122191A (da)	1991-06-24	Benzimidazolderivat og fysiologisk acceptable salte heraf samt fremgangsmaade til fremstilling af samme
SE8600658D0 (sv)	1986-02-14	Novel composition of matter
SE8704049D0 (sv)	1987-10-16	Novel pharmacological compounds
JO1519B1 (en)	1989-01-25	New compounds (new benzimidazole derivatives are effective as ulcers)