NO882226L - Fibrinolytiske proteiner. - Google Patents

Fibrinolytiske proteiner.

Info

Publication number: NO882226L
Authority: NO; Norway
Prior art keywords: fibrinolytic proteins; fibrinolytic; proteins
Prior art date: 1987-05-22

Application number

NO882226A

Other languages

English (en)

Other versions

NO882226D0 (no

Inventor

Eileen R Mulvihill

Donald C Foster

Patrick J O'hara

Anur Ashok Kumar

Donald D Rao

Margaret Y Insley

Original Assignee

Zymogenetics Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-05-22

Filing date

1988-05-20

Publication date

1988-11-23

1988-05-20 Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc

1988-05-20 Publication of NO882226D0 publication Critical patent/NO882226D0/no

1988-11-23 Publication of NO882226L publication Critical patent/NO882226L/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
- C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21069—Protein C activated (3.4.21.69)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Medicinal Chemistry (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
General Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Biotechnology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Microbiology (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Gastroenterology & Hepatology (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Enzymes And Modification Thereof (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)

NO882226A 1987-05-22 1988-05-20 Fibrinolytiske proteiner. NO882226L (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US5341187A	1987-05-22	1987-05-22

Publications (2)

Publication Number	Publication Date
NO882226D0 NO882226D0 (no)	1988-05-20
NO882226L true NO882226L (no)	1988-11-23

Family

ID=21984041

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO882226A NO882226L (no)	1987-05-22	1988-05-20	Fibrinolytiske proteiner.

Country Status (7)

Country	Link
EP (1)	EP0292009A1 (no)
JP (1)	JPS6463379A (no)
KR (1)	KR880013978A (no)
AU (1)	AU626147B2 (no)
DK (1)	DK275788A (no)
FI (1)	FI882407A7 (no)
NO (1)	NO882226L (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5079159A (en) *	1983-12-27	1992-01-07	Genetics Institute, Inc.	Method for making tissue plasminogen activator
US5714372A (en) *	1985-04-22	1998-02-03	Genentech, Inc.	Tissue plasminogen activator variants
US5736134A (en) *	1985-04-22	1998-04-07	Genentech, In.C	Tissue plasminogen activator variants
US5756093A (en) *	1985-04-22	1998-05-26	Genentech, Inc.	Tissue plasminogen activator variants
US5262170A (en) *	1988-09-02	1993-11-16	Genentech, Inc.	Tissue plasminogen activator having zymogenic or fibrin specific properties and substituted at amino acid positions 296-299, DNA molecules encoding them, vectors, and host cells
US5108901A (en) *	1988-09-02	1992-04-28	Genentech, Inc.	Tissue plasminogen activator having zymogenic or fibrin specific properties
US5258180A (en) *	1988-09-02	1993-11-02	Genetech, Inc.	Tissue plasminogen activator having fibrin specific properties and deletion of amino acids 466-970, compositions and methods of treatment
US5714145A (en) *	1988-09-02	1998-02-03	Genentech, Inc.	Tissue plasminogen activator having zymogenic or fibrin specific properties
US5550042A (en) *	1989-03-06	1996-08-27	The Board Of Regents Of The University Of Texas System	Serine protease mutants of the chymotrypsin superfamily resistant to inhibition by their cognate inhibitors and genes encoding the same and serine protease inhibitor mutants and genes encoding the same
ATE226636T1 (de) *	1989-03-06	2002-11-15	Univ Texas	Serpin-resistenter t-pa; mutanten; gene
US5866413A (en) *	1989-03-06	1999-02-02	Board Of Regents Of The University Of Texas System	Pai-1 mutants
US5190756A (en) *	1989-12-01	1993-03-02	Genentech, Inc.	Methods and materials for expression of human plasminogen variant
US5087572A (en) *	1989-12-01	1992-02-11	Genentech, Inc.	Dna encoding human plasminogen modified at the cleavage site
GB8927722D0 (en) *	1989-12-07	1990-02-07	British Bio Technology	Proteins and nucleic acids
US5242688A (en) *	1990-12-24	1993-09-07	Eli Lilly And Company	Method of treating thromboembolic disorders by administration of diglycosylated t-pa variants
AU670774B2 (en) *	1991-12-16	1996-08-01	Genentech Inc.	Novel tissue plasminogen activator variants
AU665979B2 (en) *	1991-12-16	1996-01-25	Genentech Inc.	t-PA substitution variants with improved fibrin-specificity
WO1993024635A1 (en) *	1992-06-03	1993-12-09	Genentech, Inc.	Tissue plasminogen activator glycosylation variants with improved therapeutic properties
WO1997038087A2 (en)	1996-04-05	1997-10-16	Chiron Corporation	Alphaviral vector with reduced inhibition of cellular macromolecular synthesis
US6706504B1 (en)	1996-11-12	2004-03-16	The Scripps Research Institute	Tissue type plasminogen activator (t-PA) variants: compositions and methods of use
RU2006100035A (ru) *	2003-06-11	2006-08-27	Шеринг Акциенгезельшафт (De)	Новые модифицированные кориновые молекулы, имеющие замещенные активирующие последовательности, и их применение

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0125254A1 (en) *	1982-10-28	1984-11-21	Beecham Group Plc	Enzyme derivatives and their use in the treatment of thrombosis
US4753879A (en) *	1984-08-27	1988-06-28	Biogen N.V.	Modified tissue plasminogen activators
DE3588149T2 (de) *	1984-10-01	1997-10-09	Genzyme Corp	Rekombinante DNS-Verfahren und dadurch hergestellte Produkte
GB2173804B (en) *	1985-04-22	1989-07-05	Genentech Inc	Human tissue plasminogen activator mutants, methods and intermediates therefor, and compositions using such mutants
GB8513358D0 (en) *	1985-05-28	1985-07-03	Wellcome Found	Formulation
US4916071A (en) *	1985-08-14	1990-04-10	American Home Products Corporation	Poly-kringle plasminogen activator
ATE74379T1 (de) *	1985-12-23	1992-04-15	Chiron Corp	Peptidplasminogenaktivatoren.
DK43387A (da) *	1986-01-29	1987-07-30	Beecham Group Plc	Fibrinolytisk enzym
DE3789664T3 (de) *	1986-01-31	2004-09-16	Genetics Institute, LLC, Cambridge	Neue thrombolytische proteine.
GB8608020D0 (en) *	1986-04-02	1986-05-08	Beecham Group Plc	Compounds

1988
- 1988-05-20 NO NO882226A patent/NO882226L/no unknown
- 1988-05-20 EP EP88108148A patent/EP0292009A1/en not_active Withdrawn
- 1988-05-20 FI FI882407A patent/FI882407A7/fi not_active Application Discontinuation
- 1988-05-20 DK DK275788A patent/DK275788A/da not_active Application Discontinuation
- 1988-05-23 JP JP63125612A patent/JPS6463379A/ja active Pending
- 1988-05-23 AU AU16528/88A patent/AU626147B2/en not_active Expired
- 1988-05-24 KR KR1019880006071A patent/KR880013978A/ko not_active Withdrawn

Also Published As

Publication number	Publication date
JPS6463379A (en)	1989-03-09
FI882407L (fi)	1988-11-23
FI882407A0 (fi)	1988-05-20
KR880013978A (ko)	1988-12-22
NO882226D0 (no)	1988-05-20
DK275788A (da)	1989-02-03
DK275788D0 (da)	1988-05-20
AU626147B2 (en)	1992-07-23
EP0292009A1 (en)	1988-11-23
AU1652888A (en)	1988-11-24
FI882407A7 (fi)	1988-11-23

Publication	Publication Date	Title
FI884993L (fi)	1989-05-01	Polypeptider.
DE3880632D1 (de)	1993-06-03	Kuevette.
DE3881291D1 (de)	1993-07-01	Sehapparat.
DE3862564D1 (de)	1991-05-29	Erdanker.
FI77952B (fi)	1989-01-31	Ljusbaogsrelae.
DE3867976D1 (de)	1992-03-05	Polymergebundene antioxydationsmittel.
NO881658L (no)	1988-10-17	Biofunksjonelle proteiner.
NO882226L (no)	1988-11-23	Fibrinolytiske proteiner.
DE3883705D1 (de)	1993-10-07	Alkenylbicyclohexane.
DE3876873D1 (de)	1993-02-04	Weblitzenuebergabevorrichtung.
DE3785663D1 (de)	1993-06-03	Loetgeraet.
DE3876304D1 (de)	1993-01-14	Polysilacylobutasilazane.
DE3882446D1 (de)	1993-08-26	Polydisilacyclobutasilazane.
FI882283L (fi)	1988-11-17	Proteiner med tnf-verkan.
FI880697A0 (fi)	1988-02-15	Manoeverdon foer elektriskt block.
NO881384L (no)	1988-10-03	Peptider.
NO885108L (no)	1989-05-18	Peptider.
DE3888991D1 (de)	1994-05-19	Aminokohlenwasserstoff-substituierte Ketoximosilane.
DE3870513D1 (de)	1992-06-04	Tennisball.
DE3879348D1 (de)	1993-04-22	Fm-cw-radargeraet.
DE3877421D1 (de)	1993-02-25	Polyamidbenzazole.
FI77055B (fi)	1988-09-30	Vaermegradient-inkubator.
DE3862309D1 (de)	1991-05-16	Aminomethyltetrahydrofurane.
DE3878970D1 (de)	1993-04-15	Praeparative chromatographiesaeule.
FI883943L (fi)	1989-03-08	Modifierade plasminogen-aktivatorer.