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NO873568L - Alfa-alkyl-4-amino-kinolinmetanoler og 1-(4-aralkylamino-3-kinolinyl)alkanoler, samt fremgangsmaate for fremstilling derav. - Google Patents

Alfa-alkyl-4-amino-kinolinmetanoler og 1-(4-aralkylamino-3-kinolinyl)alkanoler, samt fremgangsmaate for fremstilling derav.

Info

Publication number
NO873568L
NO873568L NO873568A NO873568A NO873568L NO 873568 L NO873568 L NO 873568L NO 873568 A NO873568 A NO 873568A NO 873568 A NO873568 A NO 873568A NO 873568 L NO873568 L NO 873568L
Authority
NO
Norway
Prior art keywords
loweralkyl
hydrogen
quinolinmethanols
aralkylamino
alkanols
Prior art date
Application number
NO873568A
Other languages
English (en)
Norwegian (no)
Other versions
NO873568D0 (no
Inventor
Richard Charles Effland
Joseph Thomas Klein
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of NO873568D0 publication Critical patent/NO873568D0/no
Publication of NO873568L publication Critical patent/NO873568L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Quinoline Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO873568A 1986-08-25 1987-08-24 Alfa-alkyl-4-amino-kinolinmetanoler og 1-(4-aralkylamino-3-kinolinyl)alkanoler, samt fremgangsmaate for fremstilling derav. NO873568L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/899,584 US4789678A (en) 1986-08-25 1986-08-25 Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds

Publications (2)

Publication Number Publication Date
NO873568D0 NO873568D0 (no) 1987-08-24
NO873568L true NO873568L (no) 1988-02-26

Family

ID=25411249

Family Applications (1)

Application Number Title Priority Date Filing Date
NO873568A NO873568L (no) 1986-08-25 1987-08-24 Alfa-alkyl-4-amino-kinolinmetanoler og 1-(4-aralkylamino-3-kinolinyl)alkanoler, samt fremgangsmaate for fremstilling derav.

Country Status (19)

Country Link
US (1) US4789678A (de)
EP (1) EP0258755B1 (de)
JP (1) JPS6360968A (de)
KR (1) KR880002834A (de)
AT (2) ATE67189T1 (de)
AU (1) AU589029B2 (de)
CA (1) CA1297111C (de)
DE (1) DE3772905D1 (de)
DK (1) DK441187A (de)
ES (1) ES2029812T3 (de)
FI (1) FI86299C (de)
GR (1) GR3003299T3 (de)
HU (1) HU199425B (de)
IL (1) IL83629A (de)
NO (1) NO873568L (de)
NZ (1) NZ221543A (de)
PH (1) PH25571A (de)
PT (1) PT85583B (de)
ZA (1) ZA876254B (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2581382B1 (fr) * 1985-05-06 1987-06-26 Sanofi Sa Derives n-(quinolyl) glycinamides, leur procede de preparation et leur application therapeutique en tant que psychotropes
GB8610981D0 (en) * 1986-05-06 1986-06-11 Ici America Inc Quinoline amides
GB8621425D0 (en) * 1986-09-05 1986-10-15 Smith Kline French Lab Compounds
US4743601A (en) * 1987-07-13 1988-05-10 Hoechst-Roussel Pharmaceuticals Inc. Dihydro-1,4-oxazino(2,3-C)quinolines
US4942168A (en) * 1987-07-13 1990-07-17 Hoechst-Roussel Pharmaceuticals Inc. Hydroxyquinoline amines, and method of enhancing memory in mammals
GB8804445D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804443D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
EP0361489A3 (de) * 1988-09-30 1991-06-12 Chugai Seiyaku Kabushiki Kaisha 3,4-Diaminochinolin- und Pyridinverbindungen
CA2011086A1 (en) * 1989-03-17 1990-09-17 Karl-Heinz Geiss 2-alkyl-4-arylmethylaminoquinolines, the use thereof and drugs prepared therefrom
US4916135A (en) * 1989-05-08 1990-04-10 Hoechst Roussel Pharmaceuticals Inc. N-heteroaryl-4-quinolinamines
GB8918265D0 (en) * 1989-08-10 1989-09-20 Smithkline Beckman Intercredit Compounds
US5110815A (en) * 1990-12-03 1992-05-05 Hoechst-Roussel Pharmaceuticals Inc. 5-amino-5,6,7,8-tetrahydroquinolines and related compounds and pharmaceutical use
GB9122051D0 (en) * 1991-10-17 1991-11-27 Univ Nottingham Medicines
US5493027A (en) * 1993-01-22 1996-02-20 Board Of Regents, The University Of Texas System Anticonvulsive agents and uses thereof
RU2247125C2 (ru) * 1999-09-22 2005-02-27 Авентис Фарма Дойчланд Гмбх Конъюгаты 4-бензиламинохинолинов с желчной кислотой и их гетероаналоги, способ их получения и лекарственные средства на основе этих соединений
CA2691450A1 (en) * 2007-08-22 2009-02-26 Abbott Gmbh & Co. Kg 4-benzylaminoquinolines, pharmaceutical compositions containing them, and their use in therapy
MX2010010773A (es) 2008-04-01 2011-04-11 Abbott Gmbh & Co Kg Tetrahidroisoquinolinas, composiciones farmaceuticas que las contienen y su uso en terapia.
AR075442A1 (es) 2009-02-16 2011-03-30 Abbott Gmbh & Co Kg Derivados de aminotetralina, composiciones farmaceuticas que las contienen y sus usos en terapia
US9051280B2 (en) 2010-08-13 2015-06-09 AbbVie Deutschland GmbH & Co. KG Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy
US8883839B2 (en) 2010-08-13 2014-11-11 Abbott Laboratories Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy
US8877794B2 (en) 2010-08-13 2014-11-04 Abbott Laboratories Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy
US8846743B2 (en) 2010-08-13 2014-09-30 Abbott Laboratories Aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy
US9045459B2 (en) 2010-08-13 2015-06-02 AbbVie Deutschland GmbH & Co. KG Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy
US9309200B2 (en) 2011-05-12 2016-04-12 AbbVie Deutschland GmbH & Co. KG Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy
TW201319049A (zh) 2011-08-05 2013-05-16 Abbott Gmbh & Co Kg 胺基□唍、胺基硫□唍及胺基－１，２，３，４－四氫喹啉衍生物，包含彼等之醫藥組合物及彼等於治療之用途
CN104011028A (zh) 2011-11-18 2014-08-27 艾伯维德国有限责任两合公司 N-取代的氨基苯并环庚烯、氨基四氢化萘、氨基茚满和苯烷基胺衍生物、包含所述衍生物的药物组合物及其在治疗中的用途
US9365512B2 (en) 2012-02-13 2016-06-14 AbbVie Deutschland GmbH & Co. KG Isoindoline derivatives, pharmaceutical compositions containing them, and their use in therapy
US9656955B2 (en) 2013-03-15 2017-05-23 Abbvie Inc. Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy
US9650334B2 (en) 2013-03-15 2017-05-16 Abbvie Inc. Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy
EP3057958B1 (de) 2013-10-17 2019-05-01 AbbVie Deutschland GmbH & Co. KG Aminotetralin- und aminoindanderivate, pharmazeutische zusammensetzungen damit und deren verwendung in der therapie
CN105992764A (zh) 2013-10-17 2016-10-05 艾伯维德国有限责任两合公司 氨基色满、氨基硫代色满及氨基-1,2,3,4-四氢喹啉衍生物，包含其的药物组合物及其在治疗中的用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2785165A (en) * 1953-12-22 1957-03-12 Abbott Lab Preparation of 4-aminoquinoline
US3391146A (en) * 1964-11-10 1968-07-02 Bristol Myers Co Nu-substituted carbamates and thiocarbamates of 2-quinolinemethanols
US4180670A (en) * 1977-02-02 1979-12-25 John Wyeth & Brother Limited Amino pyridine derivatives
FR2498187A1 (fr) * 1981-01-16 1982-07-23 Rhone Poulenc Sante Procede de preparation d'amino-4 chloro-7 quinoleines
US4631286A (en) * 1984-10-25 1986-12-23 Hoechst-Roussel Pharmaceuticals Inc. 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds
US4695573A (en) * 1984-10-25 1987-09-22 Hoechst-Roussel Pharmaceuticals Inc. 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds
EP0179383B1 (de) * 1984-10-25 1991-05-29 Hoechst-Roussel Pharmaceuticals Incorporated 9-Amino-1,2,3,4-tetrahydroacridin-1-ol und verwandte Verbindungen, Verfahren zu ihrer Herstellung und Verwendung als Arzneimittel
GB8621425D0 (en) * 1986-09-05 1986-10-15 Smith Kline French Lab Compounds
US4816456A (en) * 1986-10-01 1989-03-28 Summers William K Administration of monoamine acridines in cholinergic neuronal deficit states

Also Published As

Publication number Publication date
DE3772905D1 (de) 1991-10-17
DK441187D0 (da) 1987-08-24
US4789678A (en) 1988-12-06
IL83629A0 (en) 1988-01-31
HUT45503A (en) 1988-07-28
EP0258755B1 (de) 1991-09-11
JPS6360968A (ja) 1988-03-17
ZA876254B (en) 1988-04-27
AU7734387A (en) 1988-02-25
FI873631A0 (fi) 1987-08-21
GR3003299T3 (en) 1993-02-17
PT85583B (pt) 1990-05-31
ATE67189T1 (de) 1991-09-15
AU589029B2 (en) 1989-09-28
FI873631A7 (fi) 1988-02-26
FI86299B (fi) 1992-04-30
KR880002834A (ko) 1988-05-11
HU199425B (en) 1990-02-28
EP0258755A1 (de) 1988-03-09
IL83629A (en) 1992-02-16
FI86299C (fi) 1992-08-10
PH25571A (en) 1991-08-08
DK441187A (da) 1988-02-26
ES2029812T3 (es) 1992-10-01
NZ221543A (en) 1990-09-26
AT388729B (de) 1989-08-25
NO873568D0 (no) 1987-08-24
PT85583A (en) 1987-09-01
ATA260187A (de) 1989-01-15
CA1297111C (en) 1992-03-10

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