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NO800931L - Fremgangsmaate for fremstilling av merkapto-acyldipeptider - Google Patents

Fremgangsmaate for fremstilling av merkapto-acyldipeptider

Info

Publication number
NO800931L
NO800931L NO800931A NO800931A NO800931L NO 800931 L NO800931 L NO 800931L NO 800931 A NO800931 A NO 800931A NO 800931 A NO800931 A NO 800931A NO 800931 L NO800931 L NO 800931L
Authority
NO
Norway
Prior art keywords
acyldipeptides
procedure
preparing mercapto
mercapto
preparing
Prior art date
Application number
NO800931A
Other languages
English (en)
Other versions
NO150360C (no
NO150360B (no
Inventor
Miguel A Ondetti
Josip Pluscec
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of NO800931L publication Critical patent/NO800931L/no
Publication of NO150360B publication Critical patent/NO150360B/no
Publication of NO150360C publication Critical patent/NO150360C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06052—Val-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06165—Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
NO800931A 1979-04-02 1980-03-31 Analogifremgangsmaate for fremstilling av terapeutisk aktive merkaptoacyldipeptider NO150360C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2570179A 1979-04-02 1979-04-02

Publications (3)

Publication Number Publication Date
NO800931L true NO800931L (no) 1980-10-03
NO150360B NO150360B (no) 1984-06-25
NO150360C NO150360C (no) 1984-10-03

Family

ID=21827594

Family Applications (1)

Application Number Title Priority Date Filing Date
NO800931A NO150360C (no) 1979-04-02 1980-03-31 Analogifremgangsmaate for fremstilling av terapeutisk aktive merkaptoacyldipeptider

Country Status (22)

Country Link
JP (1) JPS55133345A (no)
AT (1) AT373577B (no)
AU (1) AU537592B2 (no)
BE (1) BE882601A (no)
CH (1) CH645092A5 (no)
DE (1) DE3012140A1 (no)
DK (1) DK140480A (no)
ES (1) ES8104200A1 (no)
FR (1) FR2453135A1 (no)
GB (1) GB2045771B (no)
GR (1) GR67752B (no)
HU (1) HU181087B (no)
IE (1) IE49653B1 (no)
IT (1) IT1147332B (no)
LU (1) LU82316A1 (no)
NL (1) NL8001675A (no)
NO (1) NO150360C (no)
NZ (1) NZ193142A (no)
PH (1) PH22024A (no)
PT (1) PT71044A (no)
SE (1) SE8002512L (no)
ZA (1) ZA801527B (no)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5692848A (en) * 1979-12-27 1981-07-27 Dainippon Pharmaceut Co Ltd Preparation of 1- 3-lower alaknoylthio-2-methylpropanoyl prolylphenylalanine
JPS56139455A (en) 1980-04-02 1981-10-30 Santen Pharmaceut Co Ltd Sulfur-containing acylaminoacid
US4336950A (en) * 1980-09-08 1982-06-29 John Zepkowski Sled
US4462943A (en) * 1980-11-24 1984-07-31 E. R. Squibb & Sons, Inc. Carboxyalkyl amino acid derivatives of various substituted prolines
JPS57142967A (en) * 1981-02-27 1982-09-03 Dainippon Pharmaceut Co Ltd N-(acylthioalkanoyloxy)succinimide and its use
US4512979A (en) * 1981-03-23 1985-04-23 Merck & Co., Inc. Dipeptides containing thialysine and related amino acids as antihypertensives
US4382081A (en) * 1981-06-12 1983-05-03 E. R. Squibb & Sons, Inc. Inhibitors of mammalian collagenase
IT1195287B (it) * 1981-11-05 1988-10-12 Ausonia Farma Srl Derivato tiazolico,procedimento per la sua preparazione e relative composizioni farmaceutiche
US4434151A (en) * 1982-11-08 1984-02-28 Medi-Physics, Inc. Bifunctional chelating agents
DE3243369A1 (de) * 1982-11-24 1984-05-24 Basf Ag, 6700 Ludwigshafen Bis-(benzoylthio)-carbonsaeuren, ihre herstellung und verwendung zur herstellung von wirkstoffen
US4642355A (en) * 1984-02-24 1987-02-10 Otsuka Pharmaceutical Factory, Inc. Proline derivatives
US4560506A (en) * 1984-05-25 1985-12-24 E. R. Squibb & Sons, Inc. Mercaptocycloalkylcarbonyl and mercaptoarylcarbonyl dipeptides
DE3432307A1 (de) * 1984-09-03 1986-04-10 Boehringer Ingelheim KG, 6507 Ingelheim Aminosaeurederivate, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
DE3436569A1 (de) * 1984-10-05 1986-04-10 Boehringer Ingelheim KG, 6507 Ingelheim Aminosaeurederivate, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
US4894437A (en) * 1985-11-15 1990-01-16 The Upjohn Company Novel renin inhibiting polypeptide analogs containing S-aryl-D- or L- or DL-cysteinyl, 3-(arylthio)lactic acid or 3-(arylthio)alkyl moieties
WO1987002986A1 (en) * 1985-11-15 1987-05-21 The Upjohn Company Novel renin inhibiting polypeptide analogs containing s-aryl-d- or l- or dl-cysteinyl, 3-(arylthio)lactic acid or 3-(arylthio)alkyl moieties
JPH0662671B2 (ja) * 1986-01-17 1994-08-17 株式会社大塚製薬工場 プロリン誘導体
EP0500989B1 (en) * 1991-02-27 1998-12-09 Lacer, S.A. N-(alpha-substituted-pyridinyl) carbonyl dipeptide antihypertensive agents
FR2679564A1 (fr) * 1991-07-23 1993-01-29 Inst Nat Sante Rech Med Nouveaux acylmercaptoalcanoldipeptides, leur preparation et les compositions qui les contiennent.
US5504080A (en) * 1992-10-28 1996-04-02 Bristol-Myers Squibb Co. Benzo-fused lactams
GB9310075D0 (en) * 1993-05-17 1993-06-30 Fujisawa Pharmaceutical Co New mercapto-amide derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same
US7390789B2 (en) * 2005-09-13 2008-06-24 William H Simmons Thio-containing inhibitors of aminopeptidase P, and compositions thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS559058A (en) * 1978-07-06 1980-01-22 Dainippon Pharmaceut Co Ltd 1-(3-mercapto-2-methylpropanoyl)prolyl amino acid derivative

Also Published As

Publication number Publication date
LU82316A1 (fr) 1980-12-16
JPS55133345A (en) 1980-10-17
IE49653B1 (en) 1985-11-13
GR67752B (no) 1981-09-18
ES490166A0 (es) 1981-04-01
CH645092A5 (de) 1984-09-14
IT8021110A0 (it) 1980-04-01
FR2453135B1 (no) 1983-06-17
SE8002512L (sv) 1980-10-03
DK140480A (da) 1980-10-03
AU5638080A (en) 1980-10-09
NZ193142A (en) 1984-08-24
NL8001675A (nl) 1980-10-06
PH22024A (en) 1988-05-13
ATA179480A (de) 1983-06-15
ES8104200A1 (es) 1981-04-01
GB2045771B (en) 1983-01-26
NO150360C (no) 1984-10-03
HU181087B (en) 1983-05-30
FR2453135A1 (fr) 1980-10-31
PT71044A (en) 1980-05-01
AT373577B (de) 1984-02-10
IT1147332B (it) 1986-11-19
DE3012140A1 (de) 1980-10-23
NO150360B (no) 1984-06-25
AU537592B2 (en) 1984-07-05
IE800638L (en) 1980-10-02
GB2045771A (en) 1980-11-05
ZA801527B (en) 1981-03-25
BE882601A (fr) 1980-10-02

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