NO800447L - Derivater av difenylhydantoin, farmasoeytiske preparater inneholdende slike preparater, samt fremgangsmaate til fremstilling av de aktive forbindelser - Google Patents
Derivater av difenylhydantoin, farmasoeytiske preparater inneholdende slike preparater, samt fremgangsmaate til fremstilling av de aktive forbindelserInfo
- Publication number
- NO800447L NO800447L NO800447A NO800447A NO800447L NO 800447 L NO800447 L NO 800447L NO 800447 A NO800447 A NO 800447A NO 800447 A NO800447 A NO 800447A NO 800447 L NO800447 L NO 800447L
- Authority
- NO
- Norway
- Prior art keywords
- difenyl
- hydantoin
- procedures
- derivatives
- preparation
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title 2
- 150000001875 compounds Chemical class 0.000 title 1
- WJRBRSLFGCUECM-UHFFFAOYSA-N hydantoin Chemical compound O=C1CNC(=O)N1 WJRBRSLFGCUECM-UHFFFAOYSA-N 0.000 title 1
- 229940091173 hydantoin Drugs 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 239000000470 constituent Substances 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 230000000506 psychotropic effect Effects 0.000 abstract 2
- MPAFAYXEPQCBPP-UHFFFAOYSA-N 1-phenylimidazolidine-2,4-dione Chemical class O=C1NC(=O)CN1C1=CC=CC=C1 MPAFAYXEPQCBPP-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- MDFFNEOEWAXZRQ-UHFFFAOYSA-N aminyl Chemical compound [NH2] MDFFNEOEWAXZRQ-UHFFFAOYSA-N 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000004043 oxo group Chemical group O=* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000446 sulfanediyl group Chemical group *S* 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/74—Two oxygen atoms, e.g. hydantoin with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7904209A FR2449448B1 (fr) | 1979-02-20 | 1979-02-20 | Composition pharmaceutique comprenant un derive de phenylhydantoine, derives mis en oeuvre et leur preparation |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO800447L true NO800447L (no) | 1980-08-21 |
| NO152047B NO152047B (no) | 1985-04-15 |
| NO152047C NO152047C (no) | 1985-07-24 |
Family
ID=9222166
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO800447A NO152047C (no) | 1979-02-20 | 1980-02-19 | Analogifremgangsmaate for fremstilling av terapeutisk virksom 5-(paradeuterofenyl)-5-fenylhydantoin |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4304782A (no) |
| EP (1) | EP0015038B1 (no) |
| JP (1) | JPS55133362A (no) |
| AT (1) | ATE10804T1 (no) |
| CA (1) | CA1139672A (no) |
| DE (1) | DE3069813D1 (no) |
| DK (1) | DK71780A (no) |
| ES (1) | ES488788A0 (no) |
| FI (1) | FI71556C (no) |
| FR (1) | FR2449448B1 (no) |
| NO (1) | NO152047C (no) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07106837B2 (ja) * | 1989-01-31 | 1995-11-15 | シャープ株式会社 | シート状体の循環式供給装置 |
| USRE35956E (en) * | 1991-01-09 | 1998-11-10 | Roussel Uclaf | Phenylimidazolidines having antiandrogenic activity |
| US5411981A (en) * | 1991-01-09 | 1995-05-02 | Roussel Uclaf | Phenylimidazolidines having antiandrogenic activity |
| JPH04297461A (ja) * | 1991-03-27 | 1992-10-21 | Otsuka Pharmaceut Factory Inc | ２−チオヒダントイン誘導体 |
| CN1087725C (zh) * | 1994-03-25 | 2002-07-17 | 同位素技术有限公司 | 用氘代方法增强药物效果 |
| US6334997B1 (en) * | 1994-03-25 | 2002-01-01 | Isotechnika, Inc. | Method of using deuterated calcium channel blockers |
| WO1999048876A1 (en) * | 1998-03-20 | 1999-09-30 | Warner-Lambert Company | Crystalline sodium phenytoin monohydrate |
| JP2002507610A (ja) * | 1998-03-25 | 2002-03-12 | ブリストル−マイヤーズ スクイブ カンパニー | イミダゾロン食欲抑制薬：ｉｉｉ．ヘテロアリール誘導体 |
| DE10214228A1 (de) * | 2002-03-22 | 2003-10-02 | Bdd Group Holding Ag Zug | Deuterierte substitutierte Indole sowie diese Verbindungen enthaltende Arzneimittel |
| NZ548209A (en) * | 2003-12-19 | 2009-07-31 | Univ California | Methods and materials for assessing prostate cancer thearapies |
| US7718684B2 (en) * | 2004-02-24 | 2010-05-18 | The Regents Of The University Of California | Methods and materials for assessing prostate cancer therapies and compounds |
| US7709517B2 (en) * | 2005-05-13 | 2010-05-04 | The Regents Of The University Of California | Diarylhydantoin compounds |
| SI2656841T1 (sl) | 2006-03-27 | 2016-11-30 | The Regents Of The University Of California | Modulator androgenih receptorjev za zdravljanje raka prostate in bolezni, povezanih z androgenimi receptorji |
| EP3020706A1 (en) | 2006-03-29 | 2016-05-18 | The Regents Of The University Of California | Diarylthiohydantoin compounds useful for the treatment of a hyperproliferative disorder |
| AR069039A1 (es) | 2007-10-26 | 2009-12-23 | Univ California | Compuestos de diarilhidantoina, composicion farmaceutica, proceso de obtencion del compuesto, utiles para desordenes hiperproliferativos |
| LT3124481T (lt) | 2010-02-16 | 2018-06-11 | Aragon Pharmaceuticals, Inc. | Androgeno receptorių moduliatoriai ir jų panaudojimas |
| AU2013323861C1 (en) | 2012-09-26 | 2024-05-02 | Aragon Pharmaceuticals, Inc. | Anti-androgens for the treatment of non-metastatic castrate-resistant prostate cancer |
| JOP20200097A1 (ar) | 2013-01-15 | 2017-06-16 | Aragon Pharmaceuticals Inc | معدل مستقبل أندروجين واستخداماته |
| TWI726969B (zh) | 2016-01-11 | 2021-05-11 | 比利時商健生藥品公司 | 用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物 |
| CN111479560A (zh) | 2017-10-16 | 2020-07-31 | 阿拉贡药品公司 | 用于治疗非转移性去势难治性前列腺癌的抗雄激素 |
-
1979
- 1979-02-20 FR FR7904209A patent/FR2449448B1/fr not_active Expired
-
1980
- 1980-02-18 AT AT80200137T patent/ATE10804T1/de not_active IP Right Cessation
- 1980-02-18 EP EP80200137A patent/EP0015038B1/fr not_active Expired
- 1980-02-18 DE DE8080200137T patent/DE3069813D1/de not_active Expired
- 1980-02-19 CA CA000346003A patent/CA1139672A/en not_active Expired
- 1980-02-19 DK DK71780A patent/DK71780A/da not_active Application Discontinuation
- 1980-02-19 NO NO800447A patent/NO152047C/no unknown
- 1980-02-20 US US06/122,903 patent/US4304782A/en not_active Expired - Lifetime
- 1980-02-20 FI FI800502A patent/FI71556C/fi not_active IP Right Cessation
- 1980-02-20 ES ES488788A patent/ES488788A0/es active Granted
- 1980-02-20 JP JP2034780A patent/JPS55133362A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FI71556B (fi) | 1986-10-10 |
| DK71780A (da) | 1980-08-21 |
| JPS55133362A (en) | 1980-10-17 |
| ATE10804T1 (de) | 1985-01-15 |
| DE3069813D1 (en) | 1985-01-31 |
| FI71556C (fi) | 1987-01-19 |
| EP0015038B1 (fr) | 1984-12-19 |
| EP0015038A1 (fr) | 1980-09-03 |
| NO152047B (no) | 1985-04-15 |
| NO152047C (no) | 1985-07-24 |
| US4304782A (en) | 1981-12-08 |
| CA1139672A (en) | 1983-01-18 |
| FR2449448B1 (fr) | 1983-05-27 |
| ES8200011A1 (es) | 1981-10-16 |
| FR2449448A1 (fr) | 1980-09-19 |
| ES488788A0 (es) | 1981-10-16 |
| FI800502A7 (fi) | 1980-08-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO800447L (no) | Derivater av difenylhydantoin, farmasoeytiske preparater inneholdende slike preparater, samt fremgangsmaate til fremstilling av de aktive forbindelser | |
| ES2137169T3 (es) | Nuevos derivados de tiazolilbenzofurano, procedimientos para su preparacion y composicion farmaceutica que los contiene. | |
| DK38982A (da) | Fremgangsmaade til fremstilling af 2-penemforbindelser | |
| NO921835D0 (no) | Fremgangsmaate for fremstilling av amidinofenylalaninderivat samt anvendelse derav | |
| HUP9801356A2 (hu) | Triciklusos (2-hidroxi-2-metil-3,3,3-trifluor-propanoil)-amino-benzoxepin-, -benzotiepin-, -benzocikloheptén-, -indén-származékok és az ezeket tartalmazó gyógyszerkészítmények | |
| SE7704256L (sv) | Nya substituerade fluoracylresorcin for lekemedel, kosmetika och pesticider samt forfarande for framstellning derav | |
| EA199801028A1 (ru) | Применение производных п-аминофенола для проготовления фармацевтических композиций, используемых при лечении нейродегенеративных заболеваний | |
| NO177995C (no) | Analogifremgangsmåte for fremstilling av terapeutisk aktive 1,3-dioksanderivater | |
| DK435583D0 (da) | Fremgangsmade til fremstilling af heterocykliske derivater af cyklobutan | |
| DK601683A (da) | Dialkylaminoalkoxybenzylalkoholderivater | |
| ES2032217T3 (es) | Nuevos derivados n-(23-vinblastinoil del acido 1-amino-metilfosfonico, sus procedimientos de preparacion y las composiciones farmaceuticas que los contienen. | |
| SE8303719L (sv) | Eburnan-oximderivat, forfarande for framstellning derav samt farmaceutiska kompositioner innehallande dessa foreningar | |
| NO803547L (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive 2-fenylamino-imidazolin-derivater | |
| SE7403176L (no) | ||
| ES491915A0 (es) | Procedimiento para la preparacion de derivados de xantina | |
| AU579416B2 (en) | 3-Amino-2,3-dihydro-1-benzoxepine-compounds and methods for their preparation and pharmaceutical preparations containing these compounds | |
| GB2014849A (en) | Compositions containing an anti- depressant and a tranquiliser | |
| SE8303718L (sv) | E-homo-enurnanderivat, forfarande for framstellning derav samt farmaceutiska kompositioner innehallande dessa foreningar | |
| GB2022583A (en) | New ionic polyiodo benzene derivatives useful as X-ray contrast media | |
| BR9706491A (pt) | Compostos de elipticina processo para a sua preparação e composições farmacêuticas contendo os mesmos |