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NO328807B1 - Nytt suksinatsalt av O-desmetyl-venlafaxine, fremgangsmate for fremstilling av disse, farmasoytisk preparat omfattende slike samt anvendelse av slike for fremstilling av medikament for behandling av sykdom - Google Patents

Nytt suksinatsalt av O-desmetyl-venlafaxine, fremgangsmate for fremstilling av disse, farmasoytisk preparat omfattende slike samt anvendelse av slike for fremstilling av medikament for behandling av sykdom Download PDF

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Publication number
NO328807B1
NO328807B1 NO20033538A NO20033538A NO328807B1 NO 328807 B1 NO328807 B1 NO 328807B1 NO 20033538 A NO20033538 A NO 20033538A NO 20033538 A NO20033538 A NO 20033538A NO 328807 B1 NO328807 B1 NO 328807B1
Authority
NO
Norway
Prior art keywords
venlafaxine
desmethyl
succinate
monosuccinate
compound according
Prior art date
Application number
NO20033538A
Other languages
English (en)
Norwegian (no)
Other versions
NO20033538L (no
NO20033538D0 (no
Inventor
Beat Theodor Weber
Anthony Francis Hadfield
Syed Muzafar Shah
Michael William Winkley
Karen Wiggins Sutherland
James Andrew Provost
Aeri Park
Rex Alwyn Shipplet
Brenton William Russell
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26952945&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO328807(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of NO20033538L publication Critical patent/NO20033538L/no
Publication of NO20033538D0 publication Critical patent/NO20033538D0/no
Publication of NO328807B1 publication Critical patent/NO328807B1/no

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C55/00Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
    • C07C55/02Dicarboxylic acids
    • C07C55/10Succinic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
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    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
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    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
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    • A61P25/00Drugs for disorders of the nervous system
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    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
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    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse
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    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
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    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/64Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
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    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
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    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
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  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
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  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Anesthesiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Psychology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO20033538A 2001-02-12 2003-08-11 Nytt suksinatsalt av O-desmetyl-venlafaxine, fremgangsmate for fremstilling av disse, farmasoytisk preparat omfattende slike samt anvendelse av slike for fremstilling av medikament for behandling av sykdom NO328807B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26821401P 2001-02-12 2001-02-12
US29796301P 2001-06-13 2001-06-13
PCT/US2002/004103 WO2002064543A2 (en) 2001-02-12 2002-02-11 Novel succinate salt of o-desmethyl-venlafaxine

Publications (3)

Publication Number Publication Date
NO20033538L NO20033538L (no) 2003-08-11
NO20033538D0 NO20033538D0 (no) 2003-08-11
NO328807B1 true NO328807B1 (no) 2010-05-18

Family

ID=26952945

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20033538A NO328807B1 (no) 2001-02-12 2003-08-11 Nytt suksinatsalt av O-desmetyl-venlafaxine, fremgangsmate for fremstilling av disse, farmasoytisk preparat omfattende slike samt anvendelse av slike for fremstilling av medikament for behandling av sykdom

Country Status (30)

Country Link
US (5) US6673838B2 (es)
EP (3) EP1360169B2 (es)
JP (1) JP4220243B2 (es)
KR (1) KR100875610B1 (es)
CN (2) CN100567253C (es)
AR (2) AR032671A1 (es)
AT (1) ATE369330T1 (es)
AU (1) AU2002250058B2 (es)
BR (1) BR0207157A (es)
CA (2) CA2666611A1 (es)
CY (1) CY1106952T1 (es)
DE (1) DE60221642T3 (es)
DK (1) DK1360169T3 (es)
EA (1) EA011451B1 (es)
ES (1) ES2290281T5 (es)
HN (1) HN2002000030A (es)
HU (1) HUP0303128A3 (es)
IL (4) IL157340A0 (es)
MX (1) MXPA03007043A (es)
NO (1) NO328807B1 (es)
NZ (1) NZ539791A (es)
PA (1) PA8539901A1 (es)
PE (1) PE20020877A1 (es)
PL (2) PL211788B1 (es)
PT (1) PT1360169E (es)
SI (1) SI1360169T1 (es)
TW (1) TWI318201B (es)
UY (1) UY27175A1 (es)
WO (1) WO2002064543A2 (es)
ZA (1) ZA200307116B (es)

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CN1955159B (zh) * 2005-06-17 2010-11-24 山东绿叶制药有限公司 用于阻断5-羟色胺以及去甲基肾上腺素再摄取的化合物,其制备方法及其用途
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CN1332946C (zh) * 2005-10-21 2007-08-22 中国人民解放军军事医学科学院放射与辐射医学研究所 作用于中枢神经系统的前药
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