NO328807B1 - Nytt suksinatsalt av O-desmetyl-venlafaxine, fremgangsmate for fremstilling av disse, farmasoytisk preparat omfattende slike samt anvendelse av slike for fremstilling av medikament for behandling av sykdom - Google Patents
Nytt suksinatsalt av O-desmetyl-venlafaxine, fremgangsmate for fremstilling av disse, farmasoytisk preparat omfattende slike samt anvendelse av slike for fremstilling av medikament for behandling av sykdom Download PDFInfo
- Publication number
- NO328807B1 NO328807B1 NO20033538A NO20033538A NO328807B1 NO 328807 B1 NO328807 B1 NO 328807B1 NO 20033538 A NO20033538 A NO 20033538A NO 20033538 A NO20033538 A NO 20033538A NO 328807 B1 NO328807 B1 NO 328807B1
- Authority
- NO
- Norway
- Prior art keywords
- venlafaxine
- desmethyl
- succinate
- monosuccinate
- compound according
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
- C07C55/02—Dicarboxylic acids
- C07C55/10—Succinic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Physical Education & Sports Medicine (AREA)
- Anesthesiology (AREA)
- Gynecology & Obstetrics (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Child & Adolescent Psychology (AREA)
- Psychology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26821401P | 2001-02-12 | 2001-02-12 | |
| US29796301P | 2001-06-13 | 2001-06-13 | |
| PCT/US2002/004103 WO2002064543A2 (en) | 2001-02-12 | 2002-02-11 | Novel succinate salt of o-desmethyl-venlafaxine |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20033538L NO20033538L (no) | 2003-08-11 |
| NO20033538D0 NO20033538D0 (no) | 2003-08-11 |
| NO328807B1 true NO328807B1 (no) | 2010-05-18 |
Family
ID=26952945
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20033538A NO328807B1 (no) | 2001-02-12 | 2003-08-11 | Nytt suksinatsalt av O-desmetyl-venlafaxine, fremgangsmate for fremstilling av disse, farmasoytisk preparat omfattende slike samt anvendelse av slike for fremstilling av medikament for behandling av sykdom |
Country Status (30)
| Country | Link |
|---|---|
| US (5) | US6673838B2 (es) |
| EP (3) | EP1360169B2 (es) |
| JP (1) | JP4220243B2 (es) |
| KR (1) | KR100875610B1 (es) |
| CN (2) | CN100567253C (es) |
| AR (2) | AR032671A1 (es) |
| AT (1) | ATE369330T1 (es) |
| AU (1) | AU2002250058B2 (es) |
| BR (1) | BR0207157A (es) |
| CA (2) | CA2666611A1 (es) |
| CY (1) | CY1106952T1 (es) |
| DE (1) | DE60221642T3 (es) |
| DK (1) | DK1360169T3 (es) |
| EA (1) | EA011451B1 (es) |
| ES (1) | ES2290281T5 (es) |
| HN (1) | HN2002000030A (es) |
| HU (1) | HUP0303128A3 (es) |
| IL (4) | IL157340A0 (es) |
| MX (1) | MXPA03007043A (es) |
| NO (1) | NO328807B1 (es) |
| NZ (1) | NZ539791A (es) |
| PA (1) | PA8539901A1 (es) |
| PE (1) | PE20020877A1 (es) |
| PL (2) | PL211788B1 (es) |
| PT (1) | PT1360169E (es) |
| SI (1) | SI1360169T1 (es) |
| TW (1) | TWI318201B (es) |
| UY (1) | UY27175A1 (es) |
| WO (1) | WO2002064543A2 (es) |
| ZA (1) | ZA200307116B (es) |
Families Citing this family (115)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20010075419A (ko) | 1998-10-30 | 2001-08-09 | 에가시라 구니오 | 안정성이 우수한 아스파르탐 유도체 결정의 결정 석출법 |
| US6342533B1 (en) | 1998-12-01 | 2002-01-29 | Sepracor, Inc. | Derivatives of (−)-venlafaxine and methods of preparing and using the same |
| CZ20013607A3 (cs) * | 1999-04-06 | 2002-06-12 | Sepracor Inc. | Farmaceutický prostředek |
| HN2002000030A (es) * | 2001-02-12 | 2004-06-07 | Wyeth Corp | Nueva sal succinato de o-desmetil-venlafaxina |
| US20050244498A1 (en) * | 2001-09-14 | 2005-11-03 | Biovail Laboratories, Inc. | Modified-release compositions of at least one form of venlafaxine |
| UA80543C2 (en) | 2001-12-04 | 2007-10-10 | Wyeth Corp | Method for the preparation of o-desmethylvenlafaxine |
| WO2003082261A1 (en) * | 2002-03-28 | 2003-10-09 | Synthon B.V. | Extended release venlafaxine formulations |
| KR20050013125A (ko) * | 2002-06-10 | 2005-02-02 | 와이어쓰 | O-데스메틸-벤라팍신의 신규한 포르메이트 염 |
| WO2004019948A1 (en) * | 2002-08-29 | 2004-03-11 | Arachnova Therapeutics Ltd. | New therapeutic uses of (4-(2-fluorophenyl)-6-methyl-2-(1-piperazinyl) thieno[2,3-d]pyrimidine |
| US7345096B2 (en) * | 2002-10-15 | 2008-03-18 | Wyeth | Use of norepinephrine reuptake modulators for preventing and treating vasomotor symptoms |
| US7429565B2 (en) | 2003-04-25 | 2008-09-30 | Gilead Sciences, Inc. | Antiviral phosphonate analogs |
| JP2004359665A (ja) * | 2003-05-30 | 2004-12-24 | Rohm & Haas Co | 生体利用性増強剤を含有する治療組成物 |
| US7402698B2 (en) | 2003-10-14 | 2008-07-22 | Wyeth | Secondary amino-and cycloamino-cycloalkanol derivatives and methods of their use |
| US7524846B2 (en) | 2003-10-14 | 2009-04-28 | Wyeth | Arylalkyl- and cycloalkylalkyl-piperazine derivatives and methods of their use |
| US7491723B2 (en) | 2003-10-14 | 2009-02-17 | Wyeth | Alkanol and cycloalkanol-amine derivatives and methods of their use |
| US7365076B2 (en) | 2003-10-14 | 2008-04-29 | Wyeth | Substituted aryl cycloalkanol derivatives and methods of their use |
| US7550485B2 (en) | 2003-10-14 | 2009-06-23 | Wyeth | Substituted N-heterocycle derivatives and methods of their use |
| US7419980B2 (en) | 2003-10-14 | 2008-09-02 | Wyeth | Fused-aryl and heteroaryl derivatives and methods of their use |
| US7531543B2 (en) | 2003-10-14 | 2009-05-12 | Wyeth | Phenylpiperazine cycloalkanol derivatives and methods of their use |
| KR20060132891A (ko) * | 2004-02-06 | 2006-12-22 | 와이어쓰 | 다중미립자 o-데스메틸벤라팍신 염 및 그의 용도 |
| US7414052B2 (en) | 2004-03-30 | 2008-08-19 | Wyeth | Phenylaminopropanol derivatives and methods of their use |
| US7517899B2 (en) | 2004-03-30 | 2009-04-14 | Wyeth | Phenylaminopropanol derivatives and methods of their use |
| US7439280B2 (en) * | 2004-04-06 | 2008-10-21 | Basf Corporation | Lignocellulosic composite material and method for preparing the same |
| JP2008507550A (ja) * | 2004-07-22 | 2008-03-13 | ワイス | 神経系障害及び状態の処置方法 |
| KR20070045278A (ko) * | 2004-07-22 | 2007-05-02 | 와이어쓰 | 신경계 질환 및 장애의 치료 방법 |
| MX2007000851A (es) * | 2004-07-22 | 2007-03-26 | Wyeth Corp | Procedimiento para el tratamiento de trastornos y dolencias del sistema nervioso. |
| HRP20070078A2 (hr) | 2004-07-27 | 2007-05-31 | Gilead Sciences | Fosfonatni analozi spojeva koji inhibiraju hiv |
| WO2006094083A1 (en) * | 2005-02-28 | 2006-09-08 | Penwest Pharmaceuticals Co. | Controlled release venlafaxine formulations |
| KR20070116607A (ko) * | 2005-03-31 | 2007-12-10 | 와이어쓰 | O-데스메틸벤라팍신 및 바제독시펜의 조합 산물 및 이의용도 |
| CN1955159B (zh) * | 2005-06-17 | 2010-11-24 | 山东绿叶制药有限公司 | 用于阻断5-羟色胺以及去甲基肾上腺素再摄取的化合物,其制备方法及其用途 |
| MX2008000249A (es) * | 2005-07-06 | 2008-03-18 | Sepracor Inc | Combinaciones de eszopiclona y o-desmetilvenlafaxina y metodos de tratamiento de menopausia y trastornos del estado de animo, ansiedad y cognitivos. |
| US7687520B2 (en) * | 2005-07-15 | 2010-03-30 | Wyeth Llc | Serotonin and norepinephrine reuptake inhibitors and uses thereof |
| RU2007149183A (ru) * | 2005-07-15 | 2009-08-20 | Вайет (Us) | Высокоселективный двойной ингибитор обратного захвата серотонина и норэпинефрина и его применение |
| US7595340B2 (en) * | 2005-07-15 | 2009-09-29 | Wyeth | Serotonin and norepinephrine reuptake inhibitor and uses thereof |
| CA2615474A1 (en) * | 2005-07-21 | 2007-02-01 | Wyeth | Method for treating nervous system disorders and conditions |
| GT200600397A (es) * | 2005-09-07 | 2007-08-28 | Formulas topicas conteniendo o-desmetil venlafaxina (odv) o sus sales | |
| GT200600396A (es) * | 2005-09-07 | 2007-04-23 | Dispositivos para la aplicacion de medicamentos transdermicos conteniendo o-desmetil venlafaxina (odv) o sus sales | |
| CN1332946C (zh) * | 2005-10-21 | 2007-08-22 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 作用于中枢神经系统的前药 |
| EP2998288B1 (en) | 2005-12-01 | 2022-08-24 | ACADIA Pharmaceuticals Inc. | Substituted phenethylamines with serotoninergic and/or norepinephrinergic activity |
| AU2006322057A1 (en) * | 2005-12-05 | 2007-06-14 | Wyeth | Process for selective synthesis of enantiomers of substituted 1-(2-amino-1-phenyl-ethyl)-cyclohexanols |
| EP1973866A1 (en) | 2005-12-20 | 2008-10-01 | Synthon B.V. | Process for making desvenlafaxine |
| JP2008546718A (ja) | 2006-04-17 | 2008-12-25 | テバ ファーマシューティカル インダストリーズ リミティド | 実質的に純粋なo−デスメチルベンラファキシン及びその調製方法。 |
| MX2007016179A (es) | 2006-04-17 | 2008-03-11 | Teva Pharma | Formas cristalinas de o-desmetilvenlafaxina. |
| PT2020996E (pt) * | 2006-05-16 | 2012-02-20 | Gilead Sciences Inc | Método e composições para tratar neoplasias malignas hematológicas |
| CA2656166A1 (en) * | 2006-07-26 | 2008-01-31 | Teva Pharmaceutical Industries Ltd. | Processes for the synthesis of o-desmethylvenlafaxine |
| US20090137846A1 (en) * | 2006-07-26 | 2009-05-28 | Valerie Niddam-Hildesheim | Processes for the synthesis of O-Desmethylvenlafaxine |
| US20080221356A1 (en) * | 2006-07-26 | 2008-09-11 | Valerie Niddam-Hildesheim | Processes for the synthesis of O-desmethylvenlafaxine |
| JP2008546850A (ja) * | 2006-07-26 | 2008-12-25 | テバ ファーマシューティカル インダストリーズ リミティド | O−デスメチルベンラファキシンの合成方法 |
| US20090069601A1 (en) * | 2006-07-26 | 2009-03-12 | Valerie Niddam-Hildesheim | Processes for the synthesis of O-desmethylvenlafaxine |
| ES2334765B1 (es) * | 2006-08-04 | 2010-12-20 | Medichem, S.A. | Proceso mejorado para sintetizar la base libre de la desvenlafaxina ysales o solvatos de la misma. |
| US20100035994A1 (en) * | 2006-08-08 | 2010-02-11 | Gore Vinayak G | Novel hydrate form of o-desmethyl venlafaxine succinate |
| US20100063160A1 (en) * | 2006-10-18 | 2010-03-11 | Merck Development Centre Private Limited | Polymorphs of o-desmethyl venlafaxine succinate |
| RU2009112105A (ru) * | 2006-10-25 | 2010-11-27 | Вайет (Us) | Выделенные гидрокси- и n-оксидные метаболиты и производные о-дезметилвенлафаксина и способы лечения |
| CN101611029B (zh) * | 2006-12-21 | 2014-09-10 | 辉瑞产品公司 | 2-((4-(1-甲基-4-(吡啶-4-基)-1h-吡唑-3-基)苯氧基)甲基)喹啉的琥珀酸盐 |
| WO2009027766A2 (en) * | 2006-12-22 | 2009-03-05 | Medichem, S.A. | New crystalline solid forms of o-desvenlafaxine base |
| US7820716B2 (en) * | 2007-01-08 | 2010-10-26 | Mai De Ltd | Crystalline polymorphs of desvenlafaxine succinate and their preparations |
| AR064987A1 (es) * | 2007-01-22 | 2009-05-06 | Medichem Sa | Proceso mejorado para sintetizar desvenlafaxina como base libre y sales o solvatos de la misma |
| AU2008211711A1 (en) * | 2007-01-31 | 2008-08-07 | Generics [Uk] Limited | Process for the preparation of O-desmethyl venlafaxine |
| US20090005457A1 (en) | 2007-02-21 | 2009-01-01 | Michael Sizensky | Solid forms comprising (-)-O-desmethylvenlafaxine and uses thereof |
| WO2008110338A1 (en) * | 2007-03-09 | 2008-09-18 | Synthon B.V. | Polymorph of desvenlafaxine succinate |
| WO2008112313A2 (en) * | 2007-03-14 | 2008-09-18 | Teva Pharmaceutical Industries Ltd. | Processes for preparing solid states of o-desmethylvenlafaxine succinate |
| DK2125698T3 (en) | 2007-03-15 | 2016-11-07 | Auspex Pharmaceuticals Inc | Deuterated d9-VENLAFAXINE |
| US20090012182A1 (en) * | 2007-06-15 | 2009-01-08 | Alexandr Jegorov | Crystal forms of O-desmethylvenlafaxine succinate |
| CA2692738A1 (en) * | 2007-07-12 | 2009-01-15 | Dr. Reddy's Laboratories, Ltd. | O-desmethylvenlafaxine |
| WO2009010990A2 (en) * | 2007-07-16 | 2009-01-22 | Matrix Laboratories Limited | Process for the preparation of o-desmethylvenlafaxine succinate polymorphic forms |
| WO2009017813A1 (en) * | 2007-08-02 | 2009-02-05 | Teva Pharmaceutical Industries Ltd. | O-desmethyl venlafaxine saccharinate |
| US20090076162A1 (en) * | 2007-09-17 | 2009-03-19 | Protia, Llc | Deuterium-enriched desvenlafaxine |
| US20100330172A1 (en) * | 2007-10-16 | 2010-12-30 | Alphapharm Pty Ltd | Controlled-release pharmaceutical formulation |
| EP2212275A2 (en) * | 2007-10-22 | 2010-08-04 | Actavis Group PTC EHF | Solid forms of (±)-o-desmethylvenlafaxine salts |
| CA2703647A1 (en) | 2007-10-26 | 2009-04-30 | Generics [Uk] Limited | Process for preparing o-desmethylvenlafaxine |
| US8063250B2 (en) * | 2007-11-26 | 2011-11-22 | Teva Pharmaceutical Industries, Ltd. | Crystal forms of O-desmethylvenlafaxine fumarate |
| EP2085377A1 (en) * | 2008-01-29 | 2009-08-05 | LEK Pharmaceuticals D.D. | Novel salts of O-desmethyl-venlafaxine |
| WO2009114685A2 (en) * | 2008-03-12 | 2009-09-17 | Dr. Reddy's Laboratories Ltd. | O-desmethylvenlafaxine salts |
| WO2009118758A2 (en) * | 2008-03-24 | 2009-10-01 | Sun Pharmaceutical Industries Ltd. | Novel crystalline forms of desvenlafaxine succinate |
| IN2008CH00818A (es) * | 2008-04-01 | 2009-10-09 | Actavis Group Ptc Ehf | |
| KR100965527B1 (ko) * | 2008-05-08 | 2010-06-23 | 제일약품주식회사 | 신규(4-(2-(디메틸아미노)-1-(1-하이드록시사이클로헥실)에틸)페녹시)포스페이트 또는 이의 약학적으로 허용가능한 염,이의 제조방법 및 이를 유효성분으로 함유하는 중추신경계질환 예방 및 치료용 조성물 |
| EP2119696A1 (en) | 2008-05-16 | 2009-11-18 | Krka | Preparation of O-desmethylvenlafaxine salts |
| EP2119695A1 (en) * | 2008-05-16 | 2009-11-18 | Krka | Preparation of O-desmethylvenlafaxine salts |
| EP2297087A2 (en) * | 2008-06-16 | 2011-03-23 | Teva Pharmaceutical Industries Ltd. | Solid states of o-desmethylvenlaf axine salts |
| PT2307435E (pt) * | 2008-07-08 | 2012-09-19 | Gilead Sciences Inc | Sais de compostos inibidores de vih |
| US20100016638A1 (en) * | 2008-07-21 | 2010-01-21 | Zdenko Hamersak | Method for preparation of o-desmethylvenlafaxine using polythiolates |
| US20110263718A1 (en) * | 2008-07-30 | 2011-10-27 | Generics [Uk] Limited | Process for the preparation of o-desmethylvenlafaxine |
| KR101041960B1 (ko) * | 2008-08-14 | 2011-06-16 | 주식회사 루미맥스테크놀러지 | 파워 led를 구비하는 램프 장치 |
| EP2191822A1 (en) | 2008-11-26 | 2010-06-02 | LEK Pharmaceuticals d.d. | Controlled release pharmaceutical compositions comprising O-desmethyl-venlafaxine |
| CZ2008756A3 (cs) * | 2008-11-27 | 2010-03-24 | Zentiva, A. S. | Zpusob prípravy desvenlafaxinu a jeho solí |
| ES2343050B1 (es) * | 2008-12-16 | 2011-06-14 | Chemo Iberica, S.A. | Procedimiento para la preparacion de desvenlafaxina y sus sales de adicion de acido farmaceuticamente aceptables. |
| CZ200969A3 (cs) * | 2009-02-06 | 2010-06-30 | Zentiva, K.S. | Nové soli desvenlafaxinu a zpusob jejich prípravy |
| CZ2009454A3 (cs) | 2009-07-15 | 2010-11-10 | Zentiva, K. S. | Zpusob prípravy desvenlafaxinu a jeho solí |
| AU2010272377A1 (en) | 2009-07-16 | 2012-01-19 | Cipla Limited | Process for the preparation of O-desmethyl venlafaxine and intermediate for use therein |
| US20110098506A1 (en) * | 2009-10-26 | 2011-04-28 | Intas Pharmaceuticals Limited | Method of preparing o-desmethylvenlafaxine |
| US8754261B2 (en) | 2009-12-16 | 2014-06-17 | Pharmathen S.A. | Process for the preparation of O-desmethyl-venlafaxine and salts thereof |
| US20110184067A1 (en) * | 2010-01-25 | 2011-07-28 | Intas Pharmaceuticals Ltd. | O-desmethylvenlafaxine succinate polymorph & process for preparing thereof |
| CA2795023A1 (en) | 2010-03-29 | 2011-10-06 | Pliva Hrvatska D.O.O. | Crystal forms of o-desmethylvenlafaxine fumarate |
| WO2011121475A2 (en) | 2010-03-31 | 2011-10-06 | Wockhardt Limited | Modified release dosage form comprising desvenlafaxine or salts thereof |
| CZ303249B6 (cs) | 2010-04-06 | 2012-06-20 | Zentiva, K.S. | Zpusob výroby 4-(2-(substituovaných)-1-(1-hydroxycyklohexyl)ethyl)fenolu O-demethylací jejich methyletheru pomocí nepáchnoucích aromatických thiolu |
| CN102212014B (zh) * | 2010-04-09 | 2013-12-25 | 江苏豪森医药集团有限公司 | O-去甲基-文拉法辛的谷氨酸盐的晶型、其制备方法及其在医药上的应用 |
| CA2788526A1 (en) | 2010-05-14 | 2011-11-17 | Alembic Limited | Extended release formulations of desvenlafaxine base |
| CN102249936B (zh) * | 2010-05-19 | 2014-09-17 | 江苏豪森医药集团有限公司 | O-去甲基文拉法辛盐酸盐的水合物及其制备方法 |
| EP2621891B1 (en) | 2010-10-01 | 2019-11-06 | Shan Dong Luye Pharmaceutical Co., Ltd. | Polymorphs of 4-[2-dimethylamino-1-(1-hydroxycyclohexyl)ethyl]phenyl 4-methylbenzoate hydrochloride, methods for preparing the same and use of the same |
| US8933123B2 (en) | 2010-10-08 | 2015-01-13 | Cadila Healthcare Limited | Polymorphic forms of O-desmethyl-venlafaxine succinate |
| EP2685966A1 (en) | 2011-03-17 | 2014-01-22 | Lupin Limited | Controlled release pharmaceutical compositions of selective serotonin reuptake inhibitor |
| WO2012140577A1 (en) | 2011-04-12 | 2012-10-18 | Lupin Limited | Modified release pharmaceutical compositions of desvenlafaxine |
| US8481596B2 (en) | 2011-06-08 | 2013-07-09 | Lupin Limited | Polymomorph of desvenlafaxine benzoate |
| TW201422255A (zh) * | 2012-10-24 | 2014-06-16 | Onyx Therapeutics Inc | 用於蛋白酶體抑制劑之調整釋放製劑 |
| CN104666291A (zh) * | 2013-11-26 | 2015-06-03 | 山东绿叶制药有限公司 | 去甲基文拉法辛苯甲酸酯类化合物在制备改善性功能障碍药物中的应用 |
| CN104352469A (zh) * | 2014-11-20 | 2015-02-18 | 哈尔滨圣吉药业股份有限公司 | 一种琥珀酸去甲文拉法辛缓释片及其制备方法 |
| CN106146323B (zh) * | 2015-04-03 | 2021-05-25 | 石药集团中奇制药技术(石家庄)有限公司 | 一种琥珀酸去甲文拉法辛一水合物新晶型及制备方法 |
| MX367362B (es) | 2016-06-29 | 2019-08-16 | Alparis Sa De Cv | Nuevas formas solidas de desvenlafaxina. |
| WO2018146529A1 (en) * | 2017-02-09 | 2018-08-16 | R L Finechem Private Limited | A process for preparation of1-[2-(dimethylamino)-1-(4-hydroxyphenyl) ethyl]-cyclohexanol and salts thereof |
| CN107082745A (zh) * | 2017-04-21 | 2017-08-22 | 上海华源医药科技发展有限公司 | 一种改进的ⅰ型去甲文拉法辛琥珀酸盐的生产方法 |
| AU2018301395B2 (en) * | 2017-07-11 | 2024-11-14 | Universal Stabilization Technologies, Inc. | Method for Preserving Biological Materials |
| WO2019027920A1 (en) | 2017-08-01 | 2019-02-07 | Gilead Sciences, Inc. | CRYSTALLINE FORMS OF ETHYL ((S) - (((((2R, 5R) -5- (6-AMINO-9H-PURIN-9-YL) -4-FLUORO-2,5-DIHYDROFURAN-2-YL) OXY ) METHYL) (PHENOXY) PHOSPHORYL) -L-ALANINATE (GS-9131) FOR THE TREATMENT OF VIRAL INFECTIONS |
| TWI805601B (zh) | 2017-08-11 | 2023-06-21 | 南韓商愛茉莉太平洋股份有限公司 | 醫藥組成物及抑制其形成結晶的方法 |
| KR102518632B1 (ko) | 2018-04-18 | 2023-04-06 | (주)아모레퍼시픽 | (r)-n-[1-(3,5-다이플루오로-4-메테인설폰일아미노-페닐)-에틸]-3-(2-프로필-6-트라이플루오로메틸-피리딘-3-일)-아크릴아마이드를 함유하는 약학 조성물 |
| TR201820634A2 (tr) | 2018-12-27 | 2020-07-21 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Desvenlafaksi̇ni̇n kati oral farmasöti̇k kompozi̇syonlari |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3536809A (en) | 1969-02-17 | 1970-10-27 | Alza Corp | Medication method |
| US3598123A (en) | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
| US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
| US4008719A (en) | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
| US4535186A (en) | 1983-04-19 | 1985-08-13 | American Home Products Corporation | 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives |
| IE56324B1 (en) * | 1982-12-13 | 1991-06-19 | American Home Prod | Phenethylamine derivatives and intermediates therefor |
| US4761501A (en) | 1983-10-26 | 1988-08-02 | American Home Products Corporation | Substituted phenylacetamides |
| IE58110B1 (en) | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
| US5073543A (en) | 1988-07-21 | 1991-12-17 | G. D. Searle & Co. | Controlled release formulations of trophic factors in ganglioside-lipsome vehicle |
| GB8902209D0 (en) | 1989-02-01 | 1989-03-22 | Wyeth John And Brother Limited | Preparation of cyclohexanol derivatives and novel thioamide intermediates |
| IT1229203B (it) | 1989-03-22 | 1991-07-25 | Bioresearch Spa | Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative. |
| US5120548A (en) | 1989-11-07 | 1992-06-09 | Merck & Co., Inc. | Swelling modulated polymeric drug delivery device |
| US5733566A (en) | 1990-05-15 | 1998-03-31 | Alkermes Controlled Therapeutics Inc. Ii | Controlled release of antiparasitic agents in animals |
| US5580578A (en) | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
| JPH07508281A (ja) | 1992-06-23 | 1995-09-14 | セプラコア インコーポレーテッド | 光学的に純粋な(+)シブトラミンを用いるうつ病およびその他の障害を治療する方法ならびに組成物 |
| CA2138998A1 (en) | 1992-06-23 | 1994-01-06 | James W. Young | Methods and compositions for treating depression and other disorders using optically pure(-) sibutramine |
| US5591767A (en) | 1993-01-25 | 1997-01-07 | Pharmetrix Corporation | Liquid reservoir transdermal patch for the administration of ketorolac |
| ES2304041T3 (es) | 1993-06-28 | 2008-09-01 | Wyeth | Nuevos tratamientos que utilizan derivados de fenetilamina. |
| TW344661B (en) * | 1993-11-24 | 1998-11-11 | Lilly Co Eli | Pharmaceutical composition for treatment of incontinence |
| DE69529109T2 (de) † | 1994-02-14 | 2003-04-30 | Wyeth, Madison | Venlafaxin und seine Analoga zum Herbeiführen einer Verbesserung der kognitiven Funktionen |
| US5594586A (en) * | 1994-05-02 | 1997-01-14 | The United States Of America As Represented By The Secretary Of The Air Force | Photorefractive limiting quadratic processor |
| IT1270594B (it) | 1994-07-07 | 1997-05-07 | Recordati Chem Pharm | Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida |
| US5506270A (en) * | 1995-01-30 | 1996-04-09 | American Home Products Corporation | Venlafaxine in the treatment of hypothalamic amenorrhea in non-depressed women |
| US5554383A (en) | 1995-04-06 | 1996-09-10 | Trustees Of Tufts College | Veterinary method for clinically modifying the behavior of dogs exhibiting canine affective aggression |
| US6274171B1 (en) | 1996-03-25 | 2001-08-14 | American Home Products Corporation | Extended release formulation of venlafaxine hydrochloride |
| EP0912577A2 (en) † | 1996-05-21 | 1999-05-06 | THE UNITED STATES OF AMERICA, as represented by the Secretary of the Department of Health and Human Services | Novel methods of o-demethylation and n-deprotection |
| EP2042161A1 (en) † | 1997-10-01 | 2009-04-01 | Novadel Pharma Inc. | Propellant-free spray composition comprising anti-emetic agent |
| US6342533B1 (en) | 1998-12-01 | 2002-01-29 | Sepracor, Inc. | Derivatives of (−)-venlafaxine and methods of preparing and using the same |
| US6197828B1 (en) | 1998-12-01 | 2001-03-06 | Sepracor, Inc. | Derivatives of (+)-venlafaxine and methods of preparing and using the same |
| CZ20013607A3 (cs) | 1999-04-06 | 2002-06-12 | Sepracor Inc. | Farmaceutický prostředek |
| WO2000072827A2 (en) † | 1999-05-27 | 2000-12-07 | Acusphere, Inc. | Porous drug matrices and methods of manufacture thereof |
| US20020022662A1 (en) | 1999-06-15 | 2002-02-21 | American Home Products Corporation | Enantiomers of O-desmethyl venlafaxine |
| AU5738700A (en) * | 1999-06-15 | 2001-01-02 | American Home Products Corporation | Enantiomers of o-desmethyl venlafaxine |
| HN2002000030A (es) * | 2001-02-12 | 2004-06-07 | Wyeth Corp | Nueva sal succinato de o-desmetil-venlafaxina |
| UA80543C2 (en) * | 2001-12-04 | 2007-10-10 | Wyeth Corp | Method for the preparation of o-desmethylvenlafaxine |
| KR20050013125A (ko) | 2002-06-10 | 2005-02-02 | 와이어쓰 | O-데스메틸-벤라팍신의 신규한 포르메이트 염 |
| TWI306092B (en) | 2003-03-11 | 2009-02-11 | Wyeth Corp | Process for preparation of phenethylamine derivatives |
| KR20060132891A (ko) | 2004-02-06 | 2006-12-22 | 와이어쓰 | 다중미립자 o-데스메틸벤라팍신 염 및 그의 용도 |
-
2002
- 2002-02-11 HN HN2002000030A patent/HN2002000030A/es unknown
- 2002-02-11 NZ NZ539791A patent/NZ539791A/en not_active IP Right Cessation
- 2002-02-11 SI SI200230609T patent/SI1360169T1/sl unknown
- 2002-02-11 US US10/073,743 patent/US6673838B2/en not_active Expired - Lifetime
- 2002-02-11 CN CNB028081129A patent/CN100567253C/zh not_active Expired - Lifetime
- 2002-02-11 CA CA002666611A patent/CA2666611A1/en not_active Abandoned
- 2002-02-11 PE PE2002000105A patent/PE20020877A1/es active IP Right Grant
- 2002-02-11 EP EP02718949.7A patent/EP1360169B2/en not_active Expired - Lifetime
- 2002-02-11 PL PL364605A patent/PL211788B1/pl unknown
- 2002-02-11 CA CA002436668A patent/CA2436668C/en not_active Expired - Lifetime
- 2002-02-11 PT PT02718949T patent/PT1360169E/pt unknown
- 2002-02-11 JP JP2002564477A patent/JP4220243B2/ja not_active Expired - Lifetime
- 2002-02-11 HU HU0303128A patent/HUP0303128A3/hu unknown
- 2002-02-11 AT AT02718949T patent/ATE369330T1/de active
- 2002-02-11 DE DE60221642.7T patent/DE60221642T3/de not_active Expired - Lifetime
- 2002-02-11 EA EA200300873A patent/EA011451B1/ru not_active IP Right Cessation
- 2002-02-11 EP EP07014868A patent/EP1864967A1/en not_active Withdrawn
- 2002-02-11 ES ES02718949.7T patent/ES2290281T5/es not_active Expired - Lifetime
- 2002-02-11 BR BR0207157-6A patent/BR0207157A/pt not_active Application Discontinuation
- 2002-02-11 IL IL15734002A patent/IL157340A0/xx unknown
- 2002-02-11 KR KR1020037010561A patent/KR100875610B1/ko not_active Expired - Lifetime
- 2002-02-11 MX MXPA03007043A patent/MXPA03007043A/es active IP Right Grant
- 2002-02-11 WO PCT/US2002/004103 patent/WO2002064543A2/en not_active Ceased
- 2002-02-11 DK DK02718949T patent/DK1360169T3/da active
- 2002-02-11 PL PL396568A patent/PL212943B1/pl unknown
- 2002-02-11 EP EP10177304A patent/EP2319826A1/en not_active Withdrawn
- 2002-02-11 AU AU2002250058A patent/AU2002250058B2/en not_active Expired
- 2002-02-11 CN CN200910206182A patent/CN101671260A/zh active Pending
- 2002-02-12 AR ARP020100463A patent/AR032671A1/es not_active Application Discontinuation
- 2002-02-13 UY UY27175A patent/UY27175A1/es active IP Right Grant
- 2002-02-14 PA PA20028539901A patent/PA8539901A1/es unknown
- 2002-02-15 TW TW091102559A patent/TWI318201B/zh not_active IP Right Cessation
-
2003
- 2003-08-11 NO NO20033538A patent/NO328807B1/no not_active IP Right Cessation
- 2003-08-11 IL IL157340A patent/IL157340A/en active IP Right Grant
- 2003-09-04 US US10/654,756 patent/US20040044241A1/en not_active Abandoned
- 2003-09-11 ZA ZA2003/07116A patent/ZA200307116B/en unknown
-
2004
- 2004-11-10 US US10/985,292 patent/US7026508B2/en not_active Expired - Fee Related
-
2006
- 2006-01-18 US US11/334,223 patent/US7291347B2/en not_active Expired - Lifetime
-
2007
- 2007-08-20 US US11/841,638 patent/US20090018208A1/en not_active Abandoned
- 2007-10-22 CY CY20071101362T patent/CY1106952T1/el unknown
-
2009
- 2009-08-05 IL IL200255A patent/IL200255A/en active IP Right Grant
-
2010
- 2010-11-18 IL IL209444A patent/IL209444A/en active IP Right Grant
-
2011
- 2011-07-01 AR ARP110102372A patent/AR082076A2/es not_active Application Discontinuation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO328807B1 (no) | Nytt suksinatsalt av O-desmetyl-venlafaxine, fremgangsmate for fremstilling av disse, farmasoytisk preparat omfattende slike samt anvendelse av slike for fremstilling av medikament for behandling av sykdom | |
| AU2002250058A1 (en) | Novel succinate salt of O-desmethyl-venlafaxine | |
| JP4445853B2 (ja) | 新規o−デスメチルベンラファクシンギ酸塩 | |
| US20180071230A1 (en) | Formulations, salts and polymorphs of transnorsertraline and uses thereof | |
| HK1057885B (en) | Succinate salt of o-desmethyl-venlafaxine | |
| HK1111679A (en) | Method for preparing o-desmethyl-venlafaxine | |
| AU2007203410A1 (en) | Novel succinate salt of o-desmethyl-venlafaxine |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |