[go: up one dir, main page]

NO324949B1 - Fremgangsmate for fremstilling av dibenzo[b,f]azepiner - Google Patents

Fremgangsmate for fremstilling av dibenzo[b,f]azepiner

Info

Publication number
NO324949B1
NO324949B1 NO20023575A NO20023575A NO324949B1 NO 324949 B1 NO324949 B1 NO 324949B1 NO 20023575 A NO20023575 A NO 20023575A NO 20023575 A NO20023575 A NO 20023575A NO 324949 B1 NO324949 B1 NO 324949B1
Authority
NO
Norway
Prior art keywords
azepines
dibenzo
preparation
Prior art date
Application number
NO20023575A
Other languages
English (en)
Norwegian (no)
Other versions
NO20023575L (no
NO20023575D0 (no
Inventor
Peter Fuenfschilling
Daniel Kaufmann
Olivier Lohse
Ulrich Beutler
Werner Zaugg
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9885081&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO324949(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NO20023575L publication Critical patent/NO20023575L/no
Publication of NO20023575D0 publication Critical patent/NO20023575D0/no
Publication of NO324949B1 publication Critical patent/NO324949B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
    • C07D223/26—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a double bond between positions 10 and 11
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/30—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/26—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
    • C07C271/28—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring to a carbon atom of a non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
    • C07D223/28—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a single bond between positions 10 and 11

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Epoxy Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
NO20023575A 2000-02-07 2002-07-26 Fremgangsmate for fremstilling av dibenzo[b,f]azepiner NO324949B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0002740.9A GB0002740D0 (en) 2000-02-07 2000-02-07 Organic compounds
PCT/EP2001/001330 WO2001056992A2 (en) 2000-02-07 2001-02-07 Dibenzo (b,f) azepine intermediates

Publications (3)

Publication Number Publication Date
NO20023575L NO20023575L (no) 2002-07-26
NO20023575D0 NO20023575D0 (no) 2002-07-26
NO324949B1 true NO324949B1 (no) 2008-01-14

Family

ID=9885081

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20023575A NO324949B1 (no) 2000-02-07 2002-07-26 Fremgangsmate for fremstilling av dibenzo[b,f]azepiner

Country Status (33)

Country Link
US (1) US7112673B2 (es)
EP (2) EP1265868B1 (es)
JP (1) JP4859322B2 (es)
KR (5) KR20020071033A (es)
CN (2) CN100455572C (es)
AR (2) AR029442A1 (es)
AT (2) ATE427938T1 (es)
AU (1) AU767724B2 (es)
BR (1) BR0107922A (es)
CA (3) CA2639210C (es)
CO (1) CO5271705A1 (es)
CY (1) CY1111567T1 (es)
CZ (1) CZ301572B6 (es)
DE (2) DE60144456D1 (es)
DK (1) DK2067772T3 (es)
ES (2) ES2324900T3 (es)
GB (1) GB0002740D0 (es)
HU (1) HU229420B1 (es)
IL (3) IL150613A0 (es)
MX (1) MXPA02007629A (es)
MY (1) MY136474A (es)
NO (1) NO324949B1 (es)
NZ (1) NZ520329A (es)
PE (1) PE20011078A1 (es)
PL (2) PL214039B1 (es)
PT (2) PT1265868E (es)
RU (1) RU2303591C2 (es)
SI (1) SI2067772T1 (es)
SK (1) SK287217B6 (es)
TR (1) TR200201655T2 (es)
TW (1) TWI284638B (es)
WO (1) WO2001056992A2 (es)
ZA (1) ZA200206219B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1302464A1 (en) * 2001-10-09 2003-04-16 Max India Limited Process for preparation of 10-methoxycarbamazepine
CA2407173C (en) 2001-10-09 2009-09-29 Max India Limited Process for the preparation of 10-methoxycarbamazepine
EP1513816A4 (en) 2002-06-14 2009-12-16 Taro Pharmaceuticals Usa Inc PROCESS FOR THE PRODUCTION OF 5H-DIBENZ (B, F) AZEPINE-5-CARBOXAMIDE
ITMI20040452A1 (it) 2004-03-09 2004-06-09 Clariant Lsm Italia Spa Processo per la preparazione di oxcarbazepina
PT1928454E (pt) 2005-05-10 2014-12-04 Intermune Inc Derivativos da piridona para modulação do sistema de proteína quinase ativada pelo stress
US7722898B2 (en) * 2006-04-26 2010-05-25 Supernus Pharmaceuticals, Inc. Modified-release preparations containing oxcarbazepine and derivatives thereof
US20090082335A1 (en) * 2007-09-26 2009-03-26 Protia, Llc Deuterium-enriched oxcarbazepine
EP2296653B1 (en) 2008-06-03 2016-01-27 Intermune, Inc. Compounds and methods for treating inflammatory and fibrotic disorders
EP2900640A1 (en) 2012-09-26 2015-08-05 Ranbaxy Laboratories Limited Process for the preparation of oxcarbazepine and its use as intermediate in the preparation of eslicarbazepine acetate
AR092742A1 (es) 2012-10-02 2015-04-29 Intermune Inc Piridinonas antifibroticas
CA2923835C (en) 2013-09-11 2022-11-29 The Administrators Of The Tulane Educational Fund Novel anthranilic amides and the use thereof
WO2015153683A1 (en) 2014-04-02 2015-10-08 Intermune, Inc. Anti-fibrotic pyridinones

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4847374A (en) * 1987-01-27 1989-07-11 Ciba-Geigy Corporation Process for the manufacture of N,N-(Dibenzohexatrienylene)ureas
DE4305502A1 (de) * 1993-02-23 1994-08-25 Basf Ag Ortho-substituierte 2-Methoxyiminophenylessigsäuremethylamide
IT1272897B (it) * 1995-01-13 1997-07-01 I F C Iniziative Finanziaarie Processo per la produzione di 10-oxo-10,11-diidro-sh- -dibenz(b,f) azepin-5-carbossiammide
US6355680B1 (en) * 1996-02-20 2002-03-12 Exocell, Inc. Albumin-binding compounds that prevent nonenzymatic glycation and that may be used for treatment of glycation-related pathologies
IT1283594B1 (it) * 1996-04-12 1998-04-22 Trifarma Srl Derivati della 5h-dibenz- (b,f)-azepin-5-carbossiammide, loro preparazione e uso come sostanze ad azione medicinale
AU756586C (en) * 1997-07-01 2004-01-29 Warner-Lambert Company 2-(4-bromo or 4-iodo phenylamino) benzoic acid derivatives and their use as MEK inhibitors
US6048856A (en) 1997-12-17 2000-04-11 Novo Nordisk A/S Heterocyclic compounds

Also Published As

Publication number Publication date
BR0107922A (pt) 2002-10-22
IL150613A0 (en) 2003-02-12
DE60138271D1 (de) 2009-05-20
PT1265868E (pt) 2009-07-15
MXPA02007629A (es) 2002-12-13
CN1244563C (zh) 2006-03-08
NZ520329A (en) 2003-11-28
PE20011078A1 (es) 2001-11-16
NO20023575L (no) 2002-07-26
KR20020071033A (ko) 2002-09-11
US20030032800A1 (en) 2003-02-13
JP4859322B2 (ja) 2012-01-25
JP2003521536A (ja) 2003-07-15
PT2067772E (pt) 2011-07-13
ES2324900T3 (es) 2009-08-19
IL188183A (en) 2011-02-28
KR20080003016A (ko) 2008-01-04
US7112673B2 (en) 2006-09-26
CA2724295C (en) 2011-07-26
PL217225B1 (pl) 2014-06-30
HUP0300243A2 (hu) 2003-06-28
SI2067772T1 (sl) 2011-08-31
PL356404A1 (en) 2004-06-28
CZ301572B6 (cs) 2010-04-21
TWI284638B (en) 2007-08-01
NO20023575D0 (no) 2002-07-26
KR100931753B1 (ko) 2009-12-14
EP2067772B1 (en) 2011-04-13
RU2303591C2 (ru) 2007-07-27
RU2002123334A (ru) 2004-01-10
ATE505459T1 (de) 2011-04-15
AU767724B2 (en) 2003-11-20
MY136474A (en) 2008-10-31
WO2001056992A3 (en) 2002-01-24
CA2724295A1 (en) 2001-08-09
HUP0300243A3 (en) 2005-07-28
IL150613A (en) 2010-05-17
AU4237301A (en) 2001-08-14
EP2067772A3 (en) 2009-08-19
ATE427938T1 (de) 2009-04-15
PL392476A1 (pl) 2010-11-22
KR101216285B1 (ko) 2012-12-28
KR20080103608A (ko) 2008-11-27
GB0002740D0 (en) 2000-03-29
HK1052501A1 (en) 2003-09-19
ES2363490T3 (es) 2011-08-05
CA2639210C (en) 2011-05-03
SK11262002A3 (sk) 2003-02-04
DK2067772T3 (da) 2011-07-18
CO5271705A1 (es) 2003-04-30
CN1721409A (zh) 2006-01-18
ZA200206219B (en) 2003-04-04
CZ20022676A3 (cs) 2002-11-13
DE60144456D1 (de) 2011-05-26
TR200201655T2 (tr) 2002-11-21
AR079237A2 (es) 2012-01-04
KR20100018069A (ko) 2010-02-16
PL214039B1 (pl) 2013-06-28
WO2001056992A2 (en) 2001-08-09
SK287217B6 (sk) 2010-03-08
KR100966209B1 (ko) 2010-06-25
CA2639210A1 (en) 2001-08-09
KR20090102882A (ko) 2009-09-30
EP2067772A2 (en) 2009-06-10
AR029442A1 (es) 2003-06-25
EP1265868B1 (en) 2009-04-08
CN1394204A (zh) 2003-01-29
CA2395601C (en) 2010-01-05
CA2395601A1 (en) 2001-08-09
HU229420B1 (en) 2013-12-30
EP1265868A2 (en) 2002-12-18
CN100455572C (zh) 2009-01-28
CY1111567T1 (el) 2015-10-07

Similar Documents

Publication Publication Date Title
NO20030012L (no) Fremgangsmåte for fremstilling av substituerte oktanoylamider
GB2356199B (en) Process for the preparation of pure citalopram
HU0103291D0 (en) Process for the preparation of citalopram
ZA200110179B (en) Process for the preparation of pure citalopram.
NO324949B1 (no) Fremgangsmate for fremstilling av dibenzo[b,f]azepiner
AU2001281275A1 (en) Processes for the preparation of oligonucleotides
DK1958938T3 (da) Fremgangsmåde til fremstilling af 10,11-dihydro-10-oxo-5H-dibenz[b,f]azepin-5-carboxamid
IL187126A0 (en) Process for the preparation of 4 - haloalkylnicotinonitriles
NO20025423L (no) Fremgangsmate for fremstilling av Citalopram
NO20030515D0 (no) Fremgangsmåte for fremstilling av dinapsolin
NO20021118D0 (no) Fremgangsmåte for fremstilling av citalopram
NO20020059D0 (no) Fremgangsmåte for fremstilling av dibenzotiazepinderivater
AU2002229648A1 (en) A process for the preparation of citalopram
IL150897A0 (en) Process for the preparation of acetyl-amidiniophenylalanyl cyclohexylglycyl-pyridinioalaninamides
NO20023702L (no) Fremgangsmåte for fremstilling av 5-arylnikotinaldehyder
IL190807A0 (en) Process for the preparation of 2-aminoethylpyridines
IL137364A (en) Process for the preparation of 6,6-dimethylhept-1-en-4-yn-3-ol
HUP0101447A3 (en) Process for the preparation of 5h-dibenz[b,f]azepine of high purity
HUP0301648A3 (en) Process for the preparation of 9-amino substituted 9,10-dihydropyrrolo [2,1-b][1,3]benzotiazepines
GB0012249D0 (en) Process for the preparation of 11-oxaprostaglandins
GB2359811B (en) Process for the preparation of pure citalopram
TR199900688A3 (tr) 4-amino-1-metil-3-n-propilpirazol 5-karboksamid hazirlanmasi için proses.
GB0012996D0 (en) Process for the preparation of endo-5-norbornene-2-ol
HU0003616D0 (en) Process for the preparation of pyridyl-ketone
GB0028881D0 (en) Process for the preparation of endo-5-norbornene-2-ol

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees